Page last updated: 2024-10-22

antipyrine and Neuroblastoma

antipyrine has been researched along with Neuroblastoma in 1 studies

Antipyrine: An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
antipyrine : A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2.

Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)

Research Excerpts

ExcerptRelevanceReference
"Edaravone treatment significantly elevated cell viability, reduced apoptotic rate, attenuated oxidative stress and improved mitochondrial membrane potential in N2a/Swe."5.38Protective effect of edaravone against Alzheimer's disease-relevant insults in neuroblastoma N2a cells. ( Gong, K; Gong, Y; Ma, T; Tang, P; Yan, Y; Zhang, L; Zhang, X; Zhao, N, 2012)
"Edaravone treatment significantly elevated cell viability, reduced apoptotic rate, attenuated oxidative stress and improved mitochondrial membrane potential in N2a/Swe."1.38Protective effect of edaravone against Alzheimer's disease-relevant insults in neuroblastoma N2a cells. ( Gong, K; Gong, Y; Ma, T; Tang, P; Yan, Y; Zhang, L; Zhang, X; Zhao, N, 2012)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yan, Y1
Gong, K1
Ma, T1
Zhang, L1
Zhao, N1
Zhang, X1
Tang, P1
Gong, Y1

Other Studies

1 other study available for antipyrine and Neuroblastoma

ArticleYear
Protective effect of edaravone against Alzheimer's disease-relevant insults in neuroblastoma N2a cells.
    Neuroscience letters, 2012, Dec-07, Volume: 531, Issue:2

    Topics: Alzheimer Disease; Animals; Antipyrine; Apoptosis; Blotting, Western; Cell Line, Tumor; Cell Surviva

2012