Page last updated: 2024-10-17

3-hydroxybutyric acid and Neuroblastoma

3-hydroxybutyric acid has been researched along with Neuroblastoma in 5 studies

3-Hydroxybutyric Acid: BUTYRIC ACID substituted in the beta or 3 position. It is one of the ketone bodies produced in the liver.
3-hydroxybutyric acid : A straight-chain 3-hydroxy monocarboxylic acid comprising a butyric acid core with a single hydroxy substituent in the 3- position; a ketone body whose levels are raised during ketosis, used as an energy source by the brain during fasting in humans. Also used to synthesise biodegradable plastics.

Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)

Research Excerpts

ExcerptRelevanceReference
"SH-SY5Y cells (human neuroblastoma cell line) were exposed to an inhibitor (WZB117) of several types of glucose transporters."4.31GLUT inhibitor WZB117 induces cytotoxicity with increased production of amyloid-beta peptide in SH-SY5Y cells preventable by beta-hydroxybutyrate: implications in Alzheimer's disease. ( Chakrabarti, S; Chakrabarti, SS; Chandan, G; Ganguly, U; Pal, S; Saini, AK; Saini, RV; Singh, S, 2023)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19903 (60.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's2 (40.00)2.80

Authors

AuthorsStudies
Koppel, SJ2
Wilkins, HM2
Weidling, IW2
Wang, X2
Menta, BW2
Swerdlow, RH2
Chandan, G1
Ganguly, U1
Pal, S1
Singh, S1
Saini, RV1
Chakrabarti, SS1
Saini, AK1
Chakrabarti, S1
Patel, MS2
Russell, JJ1
Gershman, H1
Haney, PM1
Bolinger, L1
Raefsky, C1
Roeder, LM1
Poduslo, SE1
Tildon, JT1

Other Studies

5 other studies available for 3-hydroxybutyric acid and Neuroblastoma

ArticleYear
β-Hydroxybutyrate preferentially enhances neuron over astrocyte respiration while signaling cellular quiescence.
    Mitochondrion, 2023, Volume: 68

    Topics: 3-Hydroxybutyric Acid; Cell Line, Tumor; Humans; Ketone Bodies; Neuroblastoma; Neurons; Phosphatidyl

2023
β-Hydroxybutyrate preferentially enhances neuron over astrocyte respiration while signaling cellular quiescence.
    Mitochondrion, 2023, Volume: 68

    Topics: 3-Hydroxybutyric Acid; Cell Line, Tumor; Humans; Ketone Bodies; Neuroblastoma; Neurons; Phosphatidyl

2023
β-Hydroxybutyrate preferentially enhances neuron over astrocyte respiration while signaling cellular quiescence.
    Mitochondrion, 2023, Volume: 68

    Topics: 3-Hydroxybutyric Acid; Cell Line, Tumor; Humans; Ketone Bodies; Neuroblastoma; Neurons; Phosphatidyl

2023
β-Hydroxybutyrate preferentially enhances neuron over astrocyte respiration while signaling cellular quiescence.
    Mitochondrion, 2023, Volume: 68

    Topics: 3-Hydroxybutyric Acid; Cell Line, Tumor; Humans; Ketone Bodies; Neuroblastoma; Neurons; Phosphatidyl

2023
GLUT inhibitor WZB117 induces cytotoxicity with increased production of amyloid-beta peptide in SH-SY5Y cells preventable by beta-hydroxybutyrate: implications in Alzheimer's disease.
    Pharmacological reports : PR, 2023, Volume: 75, Issue:2

    Topics: 3-Hydroxybutyric Acid; Alzheimer Disease; Amyloid beta-Peptides; Animals; Cell Line, Tumor; Glucose;

2023
Ketone-body metabolism in glioma and neuroblastoma cells.
    Proceedings of the National Academy of Sciences of the United States of America, 1981, Volume: 78, Issue:11

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acetyl-CoA C-Acetyltransferase; Animals; Cell Line; Coenzyme A

1981
Turnover of succinyl-CoA:3-oxoacid CoA-transferase in glioma and neuroblastoma cells. Specific influence of acetoacetate in neuroblastoma cells.
    The Biochemical journal, 1984, Nov-15, Volume: 224, Issue:1

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Cell Line; Coenzyme A-Transferases; Electrophoresis,

1984
Utilization of ketone bodies and glucose by established neural cell lines.
    Journal of neuroscience research, 1982, Volume: 8, Issue:4

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Astrocytoma; Brain; Cell Line; Cells, Cultured; Gluco

1982