maprotiline has been researched along with Neuroblastoma in 1 studies
Maprotiline: A bridged-ring tetracyclic antidepressant that is both mechanistically and functionally similar to the tricyclic antidepressants, including side effects associated with its use.
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Maprotiline is a tetracyclic antidepressant and possesses a highly selective norepinephrine reuptake ability." | 1.39 | Mechanism of maprotiline-induced apoptosis: role of [Ca2+](i), ERK, JNK and caspase-3 signaling pathways. ( Chang, CH; Chi, MC; Chou, CT; Jan, CR; Kuo, CC; Liao, WC; Lin, PY; Sheu, ML; Su, JA; Teng, CC, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jan, CR | 1 |
| Su, JA | 1 |
| Teng, CC | 1 |
| Sheu, ML | 1 |
| Lin, PY | 1 |
| Chi, MC | 1 |
| Chang, CH | 1 |
| Liao, WC | 1 |
| Kuo, CC | 1 |
| Chou, CT | 1 |
1 other study available for maprotiline and Neuroblastoma
| Article | Year |
|---|---|
Mechanism of maprotiline-induced apoptosis: role of [Ca2+](i), ERK, JNK and caspase-3 signaling pathways.
Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents, Second-Generation; Apoptosis; Calcium; | 2013 |