Page last updated: 2024-11-04

sanguinarine and Neuroblastoma

sanguinarine has been researched along with Neuroblastoma in 1 studies

benzophenanthridine alkaloid : A specific group of isoquinoline alkaloids that occur only in higher plants and are constituents mainly of the Papaveraceae family.

Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)

Research Excerpts

ExcerptRelevanceReference
"Sanguinarine treatment did not affect apoptototic gene expression but decreased levels of anti-apoptotic genes NOL3 and BCL2L2 in SH-SY5Y cells."5.40Promoting effects of sanguinarine on apoptotic gene expression in human neuroblastoma cells. ( Aktas, S; Altun, Z; Cecen, E; Ercetin, P; Olgun, N, 2014)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cecen, E1
Altun, Z1
Ercetin, P1
Aktas, S1
Olgun, N1

Other Studies

1 other study available for sanguinarine and Neuroblastoma

ArticleYear
Promoting effects of sanguinarine on apoptotic gene expression in human neuroblastoma cells.
    Asian Pacific journal of cancer prevention : APJCP, 2014, Volume: 15, Issue:21

    Topics: Apoptosis; Apoptosis Regulatory Proteins; Benzophenanthridines; Cell Line, Tumor; Cell Survival; Cis

2014