n-acetylserotonin has been researched along with Neuroblastoma in 2 studies
N-acetylserotonin : An N-acylserotonin resulting from the formal condensation of the primary amino group of serotonin with the carboxy group of acetic acid.
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Normelatonin was more protective against hydrogen peroxide (H2O2) and glutamate-induced cell death in SK-N-MC cells compared to melatonin which was more effective to protect primary cerebellar granular neurons against the toxicity of H2O2, glutamate and N-methyl-D-aspartate when compared to normelatonin." | 1.30 | N-acetyl-serotonin (normelatonin) and melatonin protect neurons against oxidative challenges and suppress the activity of the transcription factor NF-kappaB. ( Behl, C; Lezoualc'h, F; Sparapani, M, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lezoualc'h, F | 1 |
| Sparapani, M | 1 |
| Behl, C | 1 |
| Pappolla, MA | 1 |
| Simovich, MJ | 1 |
| Bryant-Thomas, T | 1 |
| Chyan, YJ | 1 |
| Poeggeler, B | 1 |
| Dubocovich, M | 1 |
| Bick, R | 1 |
| Perry, G | 1 |
| Cruz-Sanchez, F | 1 |
| Smith, MA | 1 |
2 other studies available for n-acetylserotonin and Neuroblastoma
| Article | Year |
|---|---|
N-acetyl-serotonin (normelatonin) and melatonin protect neurons against oxidative challenges and suppress the activity of the transcription factor NF-kappaB.
Topics: Animals; Cell Survival; Cerebellar Nuclei; Electrophoresis, Polyacrylamide Gel; Glutamic Acid; Hydro | 1998 |
The neuroprotective activities of melatonin against the Alzheimer beta-protein are not mediated by melatonin membrane receptors.
Topics: 5-Methoxytryptamine; Amyloid beta-Peptides; Animals; Antioxidants; Cells, Cultured; Cyclic N-Oxides; | 2002 |