scutellarein has been researched along with Neuroblastoma* in 1 studies
1 other study(ies) available for scutellarein and Neuroblastoma
Article | Year |
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Synthesis and biological evaluation of scutellarein derivatives as neuroprotective agents via activating Nrf2/HO-1 pathway.
Oxidative stress has been considered as the main factor of neurodegenerative diseases. Activation of the Nrf2/HO-1 pathway, as one of the most crucial endogenous protection systems, was regarded as an effective strategy to against oxidative injury. Here, a series of phosphate esters or phosphonates of scutellarein derivatives were designed, synthesized and evaluated on SH-SY5Y cell lines to examine neuroprotective effects against H Topics: Apigenin; Apoptosis; Heme Oxygenase-1; Humans; Hydrogen Peroxide; Molecular Structure; Neuroblastoma; Neuroprotective Agents; NF-E2-Related Factor 2; Oxidative Stress; Signal Transduction | 2022 |