Proteins > Protein-serine O-palmitoleoyltransferase porcupine
Page last updated: 2024-08-08 00:16:37
Protein-serine O-palmitoleoyltransferase porcupine
A protein-serine O-palmitoleoyltransferase porcupine that is encoded in the genome of mouse. [OMA:Q9JJJ7, PRO:DNx]
Synonyms
mPORC;
EC 2.3.1.250
Research
Bioassay Publications (5)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (3)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| lgk974 | Mus musculus (house mouse) | IC50 | 0.0007 | 3 | 3 |
| g007-lk | Mus musculus (house mouse) | IC50 | 0.0250 | 1 | 1 |
Drugs with Activation Measurements
Discovery and characterization of a potent Wnt and hedgehog signaling pathways dual inhibitor.European journal of medicinal chemistry, , Apr-10, Volume: 149, 2018
Discovery of Pyridinyl Acetamide Derivatives as Potent, Selective, and Orally Bioavailable Porcupine Inhibitors.ACS medicinal chemistry letters, , Jul-14, Volume: 7, Issue:7, 2016
Design, synthesis, and evaluation of novel porcupine inhibitors featuring a fused 3-ring system based on the 'reversed' amide scaffold.Bioorganic & medicinal chemistry, , 11-15, Volume: 24, Issue:22, 2016