Page last updated: 2024-08-21

phenazocine and Neuroblastoma

phenazocine has been researched along with Neuroblastoma in 7 studies

*Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51) [MeSH]

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19904 (57.14)18.7374
1990's2 (28.57)18.2507
2000's1 (14.29)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Jacobson, AE; Klee, WA; Rice, KC; Shiotani, S1
Dayag, M; Gil-Ad, I; Levkovitz, Y; Shtaif, B; Weizman, A; Zeldich, E1
Dawson, G; McLawhon, RW; Miller, RJ; West, RE1
Gillard, J; Knight, AR; Middlemiss, DN; Wong, EH1
Bell, JA; London, ED; Spivak, CE; Su, TP; Wu, XZ1
Kushner, L; Zukin, RS; Zukin, SR1
Gundlach, AL; Largent, BL; Snyder, SH1

Other Studies

7 other study(ies) available for phenazocine and Neuroblastoma

ArticleYear
N-(2,4,5-Trihydroxyphenehtyl)normetazocine, a potential irreversible inhibitor of the narcotic receptor.
    Journal of medicinal chemistry, 1977, Volume: 20, Issue:5

    Topics: Adenylyl Cyclases; Analgesics, Opioid; Animals; Benzomorphans; Brain; Cyclazocine; Depression, Chemical; In Vitro Techniques; Male; Mice; Morphinans; Neoplasms, Experimental; Neuroblastoma; Norepinephrine; Protein Binding; Rats; Receptors, Opioid

1977
Characterization of phenothiazine-induced apoptosis in neuroblastoma and glioma cell lines: clinical relevance and possible application for brain-derived tumors.
    Journal of molecular neuroscience : MN, 2004, Volume: 22, Issue:3

    Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Calmodulin; Caspase 3; Caspases; Cell Division; Cell Line, Tumor; Cell Survival; DNA Fragmentation; Dose-Response Relationship, Drug; Fluphenazine; Glioma; Humans; Mice; Mice, Inbred ICR; Neuroblastoma; Phenazocine; Phenothiazines; Rats; Receptors, sigma; Thioridazine; Up-Regulation

2004
Distinct high-affinity binding sites for benzomorphan drugs and enkephalin in a neuroblastoma--brain hybrid cell line.
    Proceedings of the National Academy of Sciences of the United States of America, 1981, Volume: 78, Issue:7

    Topics: Analgesics, Opioid; Animals; Benzomorphans; Binding Sites; Binding, Competitive; Brain; Cell Line; Cyclazocine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; Hybrid Cells; Kinetics; Morphinans; Neuroblastoma; Phenazocine; Rats; Receptors, Opioid

1981
The human sigma site, which resembles that in NCB20 cells, may correspond to a low-affinity site in guinea pig brain.
    Neuroscience letters, 1991, Oct-14, Volume: 131, Issue:2

    Topics: Animals; Brain Chemistry; Cells, Cultured; Cerebral Cortex; Cricetinae; Cricetulus; Dopamine Agents; Guanidines; Guinea Pigs; Humans; Kinetics; Male; Mice; Neuroblastoma; Pentazocine; Phenazocine; Piperidines; Radioligand Assay; Receptors, Opioid; Receptors, sigma; Stereoisomerism; Tumor Cells, Cultured

1991
Electrophysiological and binding studies on intact NCB-20 cells suggest presence of a low affinity sigma receptor.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 257, Issue:1

    Topics: Animals; Cricetinae; Cricetulus; Hybrid Cells; Ligands; Mice; Neuroblastoma; Phenazocine; Piperidines; Potassium Channels; Receptors, Opioid; Receptors, sigma; Stereoisomerism; Tumor Cells, Cultured

1991
Characterization of opioid, sigma, and phencyclidine receptors in the neuroblastoma-brain hybrid cell line NCB-20.
    Molecular pharmacology, 1988, Volume: 34, Issue:5

    Topics: Animals; Brain Chemistry; Cell Line; Cricetinae; Hybrid Cells; Kinetics; Mice; Neuroblastoma; Phenazocine; Phencyclidine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Phencyclidine; Receptors, sigma

1988
Sigma receptors on NCB-20 hybrid neurotumor cells labeled with (+)[3H]SKF 10,047 and (+)[3H]3-PPP.
    European journal of pharmacology, 1986, May-13, Volume: 124, Issue:1-2

    Topics: Animals; Brain; Cells, Cultured; Cricetinae; Cricetulus; Hybrid Cells; Kinetics; Neuroblastoma; Phenazocine; Phencyclidine; Piperidines; Receptors, Opioid; Receptors, Opioid, delta; Stereoisomerism

1986