n(1)-methylnicotinamide has been researched along with Neuroblastoma in 2 studies
N(1)-methylnicotinamide: RN given refers to parent cpd
1-methylnicotinamide : A pyridinium ion comprising nicotinamide having a methyl group at the 1-position. It is a metabolite of nicotinamide which was initially considered to be biologically inactive but has emerged as an anti-thrombotic and anti-inflammatory agent.
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 2 (100.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Milani, ZH | 1 |
Ramsden, DB | 2 |
Parsons, RB | 2 |
Aravindan, S | 1 |
Kadampeswaran, A | 1 |
Evans, EA | 1 |
Sandhu, KK | 1 |
Levy, ER | 1 |
Thomas, MG | 1 |
Austen, BM | 1 |
2 other studies available for n(1)-methylnicotinamide and Neuroblastoma
Article | Year |
---|---|
Neuroprotective effects of nicotinamide N-methyltransferase and its metabolite 1-methylnicotinamide.
Topics: 2,4-Dinitrophenol; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Humans; Mitochondria; N | 2013 |
The expression of nicotinamide N-methyltransferase increases ATP synthesis and protects SH-SY5Y neuroblastoma cells against the toxicity of Complex I inhibitors.
Topics: 1-Methyl-4-phenylpyridinium; Adenosine Triphosphate; Cell Line, Tumor; Electron Transport Complex I; | 2011 |