| Condition | Indicated | Relationship Strength | Studies | Trials |
|---|
Acute Confusional Senile Dementia
[description not available] | 0 | 5.71 | 6 | 1 |
Alzheimer Disease
A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57) | 0 | 5.71 | 6 | 1 |
Injuries, Spinal Cord
[description not available] | 0 | 2.6 | 1 | 0 |
Spinal Cord Injuries
Penetrating and non-penetrating injuries to the spinal cord resulting from traumatic external forces (e.g., WOUNDS, GUNSHOT; WHIPLASH INJURIES; etc.). | 0 | 2.6 | 1 | 0 |
Idiopathic Parkinson Disease
[description not available] | 0 | 3.98 | 4 | 0 |
Parkinson Disease
A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75) | 0 | 3.98 | 4 | 0 |
Brain Hemorrhage, Cerebral
[description not available] | 0 | 3.14 | 1 | 0 |
Cerebral Hemorrhage
Bleeding into one or both CEREBRAL HEMISPHERES including the BASAL GANGLIA and the CEREBRAL CORTEX. It is often associated with HYPERTENSION and CRANIOCEREBRAL TRAUMA. | 0 | 8.14 | 1 | 0 |
Hematoma
A collection of blood outside the BLOOD VESSELS. Hematoma can be localized in an organ, space, or tissue. | 0 | 3.14 | 1 | 0 |
Innate Inflammatory Response
[description not available] | 0 | 3.51 | 7 | 0 |
Inflammation
A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function. | 0 | 3.51 | 7 | 0 |
Disease Models, Animal
Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases. | 0 | 3.22 | 5 | 0 |
Experimental Lung Inflammation
Inflammation of any part, segment or lobe, of the lung parenchyma. | 0 | 2.15 | 1 | 0 |
Infections, Staphylococcal
[description not available] | 0 | 2.15 | 1 | 0 |
Pneumonia
Infection of the lung often accompanied by inflammation. | 0 | 7.15 | 1 | 0 |
Staphylococcal Infections
Infections with bacteria of the genus STAPHYLOCOCCUS. | 0 | 2.15 | 1 | 0 |
Acute Liver Injury, Drug-Induced
[description not available] | 0 | 2.15 | 1 | 0 |
Chemical and Drug Induced Liver Injury
A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment. | 0 | 2.15 | 1 | 0 |
Depression, Endogenous
[description not available] | 0 | 2.15 | 1 | 0 |
Depressive Disorder
An affective disorder manifested by either a dysphoric mood or loss of interest or pleasure in usual activities. The mood disturbance is prominent and relatively persistent. | 0 | 2.15 | 1 | 0 |
MPTP Neurotoxicity Syndrome
[description not available] | 0 | 2.15 | 1 | 0 |
Delayed Effects, Prenatal Exposure
[description not available] | 0 | 2.17 | 1 | 0 |
Anesthesia
A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures. | 0 | 2.17 | 1 | 0 |
Pregnancy
The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH. | 0 | 2.77 | 3 | 0 |
Cognition Disorders
Disorders characterized by disturbances in mental processes related to learning, thinking, reasoning, and judgment. | 0 | 2.48 | 2 | 0 |
Academic Disorder, Developmental
[description not available] | 0 | 2.08 | 1 | 0 |
Age-Related Memory Disorders
[description not available] | 0 | 2.08 | 1 | 0 |
Learning Disabilities
Conditions characterized by a significant discrepancy between an individual's perceived level of intellect and their ability to acquire new language and other cognitive skills. These may result from organic or psychological conditions. Relatively common subtypes include DYSLEXIA, DYSCALCULIA, and DYSGRAPHIA. | 0 | 2.08 | 1 | 0 |
Memory Disorders
Disturbances in registering an impression, in the retention of an acquired impression, or in the recall of an impression. Memory impairments are associated with DEMENTIA; CRANIOCEREBRAL TRAUMA; ENCEPHALITIS; ALCOHOLISM (see also ALCOHOL AMNESTIC DISORDER); SCHIZOPHRENIA; and other conditions. | 0 | 2.08 | 1 | 0 |
Lung Injury, Acute
[description not available] | 0 | 2.52 | 2 | 0 |
Acute Lung Injury
A condition of lung damage that is characterized by bilateral pulmonary infiltrates (PULMONARY EDEMA) rich in NEUTROPHILS, and in the absence of clinical HEART FAILURE. This can represent a spectrum of pulmonary lesions, endothelial and epithelial, due to numerous factors (physical, chemical, or biological). | 0 | 7.52 | 2 | 0 |
Bone Loss, Osteoclastic
[description not available] | 0 | 2.53 | 2 | 0 |
Degenerative Diseases, Central Nervous System
[description not available] | 0 | 2.13 | 1 | 0 |
Neurodegenerative Diseases
Hereditary and sporadic conditions which are characterized by progressive nervous system dysfunction. These disorders are often associated with atrophy of the affected central or peripheral nervous system structures. | 0 | 2.13 | 1 | 0 |
Arthritis, Degenerative
[description not available] | 0 | 2.13 | 1 | 0 |
Osteoarthritis
A progressive, degenerative joint disease, the most common form of arthritis, especially in older persons. The disease is thought to result not from the aging process but from biochemical changes and biomechanical stresses affecting articular cartilage. In the foreign literature it is often called osteoarthrosis deformans. | 0 | 7.13 | 1 | 0 |
Blood Poisoning
[description not available] | 0 | 2.13 | 1 | 0 |
Sepsis
Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK. | 0 | 2.13 | 1 | 0 |
Acute Kidney Failure
[description not available] | 0 | 2.13 | 1 | 0 |
Acute Kidney Injury
Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions. | 0 | 7.13 | 1 | 0 |
Injury, Ischemia-Reperfusion
[description not available] | 0 | 2.07 | 1 | 0 |
Ischemia
A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION. | 0 | 2.07 | 1 | 0 |
Reperfusion Injury
Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA. | 0 | 2.07 | 1 | 0 |
Neuroblastoma
A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51) | 0 | 2.02 | 1 | 0 |