Page last updated: 2024-10-21

3-methylcholanthrene and Neuroblastoma

3-methylcholanthrene has been researched along with Neuroblastoma in 6 studies

Methylcholanthrene: A carcinogen that is often used in experimental cancer studies.
3-methylcholanthrene : A pentacyclic ortho- and peri-fused polycyclic arene consisting of a dihydrocyclopenta[ij]tetraphene ring system with a methyl substituent at the 3-position.

Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)

Research Excerpts

ExcerptRelevanceReference
"The models discussed include brain tumors produced by local implants of carcinogenic hydrocarbons and by the administration of resorptive N-nitroso compounds, some of the cell lines derived from the latter, tumors resulting from the intracerebral inoculation of oncogenic viruses, and the differentiating neuroepithelial component of a transplantable mouse teratoma."2.36Correlation of animal brain tumor models with human neuro-oncology. ( Rubinstein, LJ, 1977)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19906 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rubinstein, LJ1
Stahn, R1
Rose, S1
Sanborn, S1
West, G1
Herschman, H1
Leibowitz, S1
Schwartz, RS1
Angel Basombrío, M1
Hellström, IE1
Hellström, KE1
Pierce, GE1
Shats, VIa1

Reviews

4 reviews available for 3-methylcholanthrene and Neuroblastoma

ArticleYear
Correlation of animal brain tumor models with human neuro-oncology.
    National Cancer Institute monograph, 1977, Volume: 46

    Topics: Animals; Brain Neoplasms; Cell Differentiation; Cell Line; Disease Models, Animal; Glioma; Humans; M

1977
Malignancy as a complication of immunosuppressive therapy.
    Advances in internal medicine, 1971, Volume: 17

    Topics: Animals; Antibiotics, Antineoplastic; Antibody Formation; Antigens, Neoplasm; Breast Neoplasms; Burk

1971
The immunology of cancer.
    Journal of oral pathology, 1973, Volume: 2, Issue:5

    Topics: Animals; Antibodies, Neoplasm; Antigen-Antibody Complex; Antigens, Neoplasm; Breast Neoplasms; Colon

1973
[Blood lymphocytes in cancer].
    Tsitologiia, 1972, Volume: 14, Issue:1

    Topics: Animals; Antigens, Neoplasm; Benz(a)Anthracenes; Child; Female; Fibrosarcoma; Humans; Lectins; Lymph

1972

Other Studies

2 other studies available for 3-methylcholanthrene and Neuroblastoma

ArticleYear
Effects of nerve growth factor administration of N-ethyl-N-nitrosourea carcinogenesis.
    Brain research, 1975, Oct-17, Volume: 96, Issue:2

    Topics: Animals; Brain Neoplasms; Cells, Cultured; Drug Interactions; Ethylnitrosourea; Female; Male; Methyl

1975
Cell-bound immune reactions against tumor specific transplantation antigens.
    Proceedings. Canadian Cancer Conference, 1969, Volume: 8

    Topics: Animals; Antigens; Child, Preschool; Colonic Neoplasms; Culture Techniques; Female; Gammaretrovirus;

1969