Page last updated: 2024-12-11
dehydroeffusol
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Description
dehydroeffusol: has anxiolytic and sedative effects, from Juncus effusus; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Related Flora
Flora | Rank | Flora Definition | Family | Family Definition |
---|---|---|---|---|
Juncus | genus | [no description available] | Juncaceae | [no description available] |
Cross-References
ID Source | ID |
---|---|
PubMed CID | 5316810 |
CHEMBL ID | 4758989 |
SCHEMBL ID | 23597741 |
MeSH ID | M0575607 |
Synonyms (12)
Synonym |
---|
FT-0665610 |
5-ethenyl-1-methylphenanthrene-2,7-diol |
dehydro effusol |
dehydroeffusol |
137319-34-7 |
DTXSID30415709 |
AKOS037515243 |
HY-N5058 |
CS-0032228 |
MS-23541 |
SCHEMBL23597741 |
CHEMBL4758989 |
Research Excerpts
Overview
Dhydroeffusol (DHE) is a phenanthrene compound that possesses anti-tumor activity. It is isolated from the Chinese medicinal plant Juncus effusus.
Excerpt | Reference | Relevance |
---|---|---|
"Dehydroeffusol (DHE) is a phenanthrene compound that possesses anti-tumor activity. " | ( Dehydroeffusol inhibits hypoxia-induced epithelial-mesenchymal transition in non-small cell lung cancer cells through the inactivation of Wnt/β-catenin pathway. Hou, T; Li, L; Wang, J; Wei, H; Zhang, F; Zhao, M, 2020) | 3.44 |
"Dehydroeffusol (DHE) is a phenanthrene isolated from the Chinese medicinal plant Juncus effusus. " | ( Shotgun Proteomics and Quantitative Pathway Analysis of the Mechanisms of Action of Dehydroeffusol, a Bioactive Phytochemical with Anticancer Activity from Juncus effusus. Cao, B; Chang, IS; Che, CM; Fung, YE; Kwong, WL; Lok, CN; Lum, CT; Sy, LK, 2018) | 2.15 |
"Dehydroeffusol is a naturally occurring phenanthrene isolated from Juncus effusus. " | ( Effects of dehydroeffusol on spasmogen-induced contractile responses of rat intestinal smooth muscles. Di, F; Huang, J; Li, P; Zhai, H, 2014) | 2.23 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Bioassays (2)
Assay ID | Title | Year | Journal | Article |
---|---|---|---|---|
AID1699005 | Antiproliferative activity against human SGC-7901 cells assessed as reduction in cell viability after 48 hrs by Alamar Blue assay | 2020 | Journal of natural products, 11-25, Volume: 83, Issue:11 | Oxidized Juncuenin B Analogues with Increased Antiproliferative Activity on Human Adherent Cell Lines: Semisynthesis and Biological Evaluation. |
AID1699006 | Antiproliferative activity against human AGS cells assessed as reduction in cell viability after 48 hrs by Alamar Blue assay | 2020 | Journal of natural products, 11-25, Volume: 83, Issue:11 | Oxidized Juncuenin B Analogues with Increased Antiproliferative Activity on Human Adherent Cell Lines: Semisynthesis and Biological Evaluation. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Research
Studies (9)
Timeframe | Studies, This Drug (%) | All Drugs % |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 7 (77.78) | 24.3611 |
2020's | 2 (22.22) | 2.80 |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 12.21
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.21) All Compounds (24.57) |
Study Types
Publication Type | This drug (%) | All Drugs (%) |
---|---|---|
Trials | 0 (0.00%) | 5.53% |
Reviews | 0 (0.00%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 9 (100.00%) | 84.16% |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |