Page last updated: 2024-12-11

dehydroeffusol

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

dehydroeffusol: has anxiolytic and sedative effects, from Juncus effusus; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

FloraRankFlora DefinitionFamilyFamily Definition
Juncusgenus[no description available]Juncaceae[no description available]

Cross-References

ID SourceID
PubMed CID5316810
CHEMBL ID4758989
SCHEMBL ID23597741
MeSH IDM0575607

Synonyms (12)

Synonym
FT-0665610
5-ethenyl-1-methylphenanthrene-2,7-diol
dehydro effusol
dehydroeffusol
137319-34-7
DTXSID30415709
AKOS037515243
HY-N5058
CS-0032228
MS-23541
SCHEMBL23597741
CHEMBL4758989

Research Excerpts

Overview

Dhydroeffusol (DHE) is a phenanthrene compound that possesses anti-tumor activity. It is isolated from the Chinese medicinal plant Juncus effusus.

ExcerptReferenceRelevance
"Dehydroeffusol (DHE) is a phenanthrene compound that possesses anti-tumor activity. "( Dehydroeffusol inhibits hypoxia-induced epithelial-mesenchymal transition in non-small cell lung cancer cells through the inactivation of Wnt/β-catenin pathway.
Hou, T; Li, L; Wang, J; Wei, H; Zhang, F; Zhao, M, 2020
)
3.44
"Dehydroeffusol (DHE) is a phenanthrene isolated from the Chinese medicinal plant Juncus effusus. "( Shotgun Proteomics and Quantitative Pathway Analysis of the Mechanisms of Action of Dehydroeffusol, a Bioactive Phytochemical with Anticancer Activity from Juncus effusus.
Cao, B; Chang, IS; Che, CM; Fung, YE; Kwong, WL; Lok, CN; Lum, CT; Sy, LK, 2018
)
2.15
"Dehydroeffusol is a naturally occurring phenanthrene isolated from Juncus effusus. "( Effects of dehydroeffusol on spasmogen-induced contractile responses of rat intestinal smooth muscles.
Di, F; Huang, J; Li, P; Zhai, H, 2014
)
2.23
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (2)

Assay IDTitleYearJournalArticle
AID1699005Antiproliferative activity against human SGC-7901 cells assessed as reduction in cell viability after 48 hrs by Alamar Blue assay2020Journal of natural products, 11-25, Volume: 83, Issue:11
Oxidized Juncuenin B Analogues with Increased Antiproliferative Activity on Human Adherent Cell Lines: Semisynthesis and Biological Evaluation.
AID1699006Antiproliferative activity against human AGS cells assessed as reduction in cell viability after 48 hrs by Alamar Blue assay2020Journal of natural products, 11-25, Volume: 83, Issue:11
Oxidized Juncuenin B Analogues with Increased Antiproliferative Activity on Human Adherent Cell Lines: Semisynthesis and Biological Evaluation.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (9)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's7 (77.78)24.3611
2020's2 (22.22)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.21

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.21 (24.57)
Research Supply Index2.30 (2.92)
Research Growth Index4.51 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.21)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other9 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]