sorbitol has been researched along with Neuroblastoma in 13 studies
D-glucitol : The D-enantiomer of glucitol (also known as D-sorbitol).
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
| Excerpt | Relevance | Reference |
|---|---|---|
| " We used a human neuroblastoma cell line, SH-SY5Y, to investigate the effect of cilostazol, a specific cAMP phosphodiesterase inhibitor, on NO production and Na+, K+-ATPase activity." | 7.70 | Cilostazol, a cyclic AMP phosphodiesterase inhibitor, stimulates nitric oxide production and sodium potassium adenosine triphosphatase activity in SH-SY5Y human neuroblastoma cells. ( Inada, H; Onaya, T; Shindo, H; Tawata, M, 1999) |
| " Neuroblastoma cells were cultured for two weeks in media containing 30 mM glucose, fructose, galactose or mannose with or without 0." | 7.69 | Reduced Na+/K+ ATPase transport activity, resting membrane potential, and bradykinin-stimulated phosphatidylinositol synthesis by polyol accumulation in cultured neuroblastoma cells. ( Davidson, EP; Dunlap, JA; Stefani, MR; Yorek, MA, 1994) |
| "myo-Inositol accumulation and incorporation into phosphoinositides was decreased in neuroblastoma cells chronically exposed to medium containing 30 mmol/L glucose or 30 mmol/L galactose." | 7.68 | Reversal of hyperglycemic-induced defects in myo-inositol metabolism and Na+/K+ pump activity in cultured neuroblastoma cells by normalizing glucose levels. ( Davidson, EP; Dunlap, JA; Stefani, MR; Yorek, MA, 1993) |
| "Neuroblastoma cells were used to examine the effect of high concentrations of glucose or galactose and accumulation of polyols on the resting membrane potential." | 7.68 | Resting membrane potential in 41A3 mouse neuroblastoma cells. Effect of increased glucose and galactose concentrations. ( Dunlap, JA; Yorek, MA, 1991) |
| "Neuroblastoma cells were used to determine the effect of high carbohydrate and polyol levels on myo-inositol metabolism." | 7.67 | myo-Inositol metabolism in 41A3 neuroblastoma cells: effects of high glucose and sorbitol levels. ( Dunlap, JA; Ginsberg, BH; Yorek, MA, 1987) |
| "Neuroblastoma cells were used to determine the effect of sorbinil on myo-inositol metabolism in cells exposed to elevated levels of glucose in culture." | 7.67 | Effect of sorbinil on myo-inositol metabolism in cultured neuroblastoma cells exposed to increased glucose levels. ( Dunlap, JA; Ginsberg, BH; Yorek, MA, 1988) |
| " We used a human neuroblastoma cell line, SH-SY5Y, to investigate the effect of cilostazol, a specific cAMP phosphodiesterase inhibitor, on NO production and Na+, K+-ATPase activity." | 3.70 | Cilostazol, a cyclic AMP phosphodiesterase inhibitor, stimulates nitric oxide production and sodium potassium adenosine triphosphatase activity in SH-SY5Y human neuroblastoma cells. ( Inada, H; Onaya, T; Shindo, H; Tawata, M, 1999) |
| " Neuroblastoma cells were cultured for two weeks in media containing 30 mM glucose, fructose, galactose or mannose with or without 0." | 3.69 | Reduced Na+/K+ ATPase transport activity, resting membrane potential, and bradykinin-stimulated phosphatidylinositol synthesis by polyol accumulation in cultured neuroblastoma cells. ( Davidson, EP; Dunlap, JA; Stefani, MR; Yorek, MA, 1994) |
| "myo-Inositol accumulation and incorporation into phosphoinositides was decreased in neuroblastoma cells chronically exposed to medium containing 30 mmol/L glucose or 30 mmol/L galactose." | 3.68 | Reversal of hyperglycemic-induced defects in myo-inositol metabolism and Na+/K+ pump activity in cultured neuroblastoma cells by normalizing glucose levels. ( Davidson, EP; Dunlap, JA; Stefani, MR; Yorek, MA, 1993) |
| "Neuroblastoma cells were used to examine the effect of high concentrations of glucose or galactose and accumulation of polyols on the resting membrane potential." | 3.68 | Resting membrane potential in 41A3 mouse neuroblastoma cells. Effect of increased glucose and galactose concentrations. ( Dunlap, JA; Yorek, MA, 1991) |
| "Neuroblastoma cells were used to determine the effect of high carbohydrate and polyol levels on myo-inositol metabolism." | 3.67 | myo-Inositol metabolism in 41A3 neuroblastoma cells: effects of high glucose and sorbitol levels. ( Dunlap, JA; Ginsberg, BH; Yorek, MA, 1987) |
| "Neuroblastoma cells were used to determine the effect of sorbinil on myo-inositol metabolism in cells exposed to elevated levels of glucose in culture." | 3.67 | Effect of sorbinil on myo-inositol metabolism in cultured neuroblastoma cells exposed to increased glucose levels. ( Dunlap, JA; Ginsberg, BH; Yorek, MA, 1988) |
| "A characteristic hallmark of Alzheimer's disease brain is the presence of hyperphosphorylated tau; however, the mechanisms responsible for the aberrant tau phosphorylation are unknown." | 1.31 | Hyperosmotic stress-induced apoptosis and tau phosphorylation in human neuroblastoma cells. ( Johnson, GV; Stoothoff, WH, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (23.08) | 18.7374 |
| 1990's | 7 (53.85) | 18.2507 |
| 2000's | 3 (23.08) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yorek, MA | 6 |
| Dunlap, JA | 6 |
| Stefani, MR | 3 |
| Davidson, EP | 2 |
| Shindo, H | 2 |
| Thomas, TP | 1 |
| Larkin, DD | 1 |
| Karihaloo, AK | 1 |
| Inada, H | 2 |
| Onaya, T | 2 |
| Stevens, MJ | 1 |
| Greene, DA | 1 |
| Tawata, M | 1 |
| Jenkins, SM | 1 |
| Zinnerman, M | 1 |
| Garner, C | 1 |
| Johnson, GV | 3 |
| Stoothoff, WH | 1 |
| Chun, W | 1 |
| Lesort, M | 1 |
| Lee, M | 1 |
| Leeney, EM | 1 |
| Wiesinger, H | 1 |
| Thiess, U | 1 |
| Hamprecht, B | 1 |
| Ginsberg, BH | 2 |
| Cecile, JP | 1 |
| Fournier, A | 1 |
| Lelong, M | 1 |
| Bayart, M | 1 |
| Regnier, G | 1 |
13 other studies available for sorbitol and Neuroblastoma
| Article | Year |
|---|---|
Reduced Na+/K+ ATPase transport activity, resting membrane potential, and bradykinin-stimulated phosphatidylinositol synthesis by polyol accumulation in cultured neuroblastoma cells.
Topics: Animals; Bradykinin; Cell Line; Fructose; Galactose; Glucose; Inositol; Kinetics; Mannose; Membrane | 1994 |
Reversal of hyperglycemic-induced defects in myo-inositol metabolism and Na+/K+ pump activity in cultured neuroblastoma cells by normalizing glucose levels.
Topics: Animals; Biological Transport; Blood Glucose; Galactose; Glucose; Hyperglycemia; Inositol; Neuroblas | 1993 |
Modulation of basal nitric oxide-dependent cyclic-GMP production by ambient glucose, myo-inositol, and protein kinase C in SH-SY5Y human neuroblastoma cells.
Topics: Base Sequence; Cholinergic Fibers; Cyclic GMP; Diabetic Neuropathies; Glucose; Humans; Inositol; Mod | 1996 |
Cilostazol, a cyclic AMP phosphodiesterase inhibitor, stimulates nitric oxide production and sodium potassium adenosine triphosphatase activity in SH-SY5Y human neuroblastoma cells.
Topics: Cilostazol; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dexamethasone; Humans; Inositol; Isoqu | 1999 |
Modulation of tau phosphorylation and intracellular localization by cellular stress.
Topics: Anisomycin; Binding Sites; Cell Compartmentation; Cytoskeleton; Enzyme Activation; Epitopes; Humans; | 2000 |
Hyperosmotic stress-induced apoptosis and tau phosphorylation in human neuroblastoma cells.
Topics: Alzheimer Disease; Apoptosis; Brain; Calcium-Calmodulin-Dependent Protein Kinases; Cysteine Proteina | 2001 |
Mutant huntingtin aggregates do not sensitize cells to apoptotic stressors.
Topics: Apoptosis; Caspase 3; Caspases; Enzyme Activation; Enzyme Inhibitors; Humans; Huntingtin Protein; Hu | 2002 |
Resting membrane potential in 41A3 mouse neuroblastoma cells. Effect of increased glucose and galactose concentrations.
Topics: Animals; Galactose; Glucose; Indicators and Reagents; Inositol; Kinetics; Membrane Potentials; Mice; | 1991 |
Effect of fructose supplementation on sorbitol accumulation and myo-inositol metabolism in cultured neuroblastoma cells exposed to increased glucose concentrations.
Topics: Aldehyde Reductase; Animals; Biological Transport; Cell Line; Cycloheximide; Fructose; Glucose; Inos | 1990 |
Sorbitol pathway activity and utilization of polyols in astroglia-rich primary cultures.
Topics: Aldehyde Reductase; Animals; Astrocytes; Cell Division; Cells, Cultured; Culture Media; DNA Replicat | 1990 |
myo-Inositol metabolism in 41A3 neuroblastoma cells: effects of high glucose and sorbitol levels.
Topics: Animals; Cell Division; Cell Line; Choline; Ethanolamine; Ethanolamines; Glucose; Inositol; Kinetics | 1987 |
Effect of sorbinil on myo-inositol metabolism in cultured neuroblastoma cells exposed to increased glucose levels.
Topics: Animals; Cell Line; Fructose; Glucose; Imidazoles; Imidazolidines; Inositol; Kinetics; Mice; Neurobl | 1988 |
Phlebo-arterio-urography in the diagnosis of abdominal masses in children.
Topics: Abdominal Neoplasms; Angiography; Child; Child, Preschool; Diatrizoate; Female; Femoral Vein; Gangli | 1972 |