disulfiram has been researched along with Neuroblastoma in 4 studies
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Acetaminophen potentiates staurosporine-mediated neuroblastoma cell death." | 7.74 | Acetaminophen potentiates staurosporine-induced death in a human neuroblastoma cell line. ( Ceña, V; Posadas, I; Prieto-Lloret, J; Santos, P; Vellecco, V, 2007) |
| " So, these results suggest that an early production of DOPAL could produce delayed toxic effects on SH-SY5Y cells." | 5.32 | Toxicity of a treatment associating dopamine and disulfiram for catecholaminergic neuroblastoma SH-SY5Y cells: relationships with 3,4-dihydroxyphenylacetaldehyde formation. ( Bonnet, JJ; Costentin, J; Dingeval, MG; Janin, F; Legros, H, 2004) |
| "Acetaminophen potentiates staurosporine-mediated neuroblastoma cell death." | 3.74 | Acetaminophen potentiates staurosporine-induced death in a human neuroblastoma cell line. ( Ceña, V; Posadas, I; Prieto-Lloret, J; Santos, P; Vellecco, V, 2007) |
| " So, these results suggest that an early production of DOPAL could produce delayed toxic effects on SH-SY5Y cells." | 1.32 | Toxicity of a treatment associating dopamine and disulfiram for catecholaminergic neuroblastoma SH-SY5Y cells: relationships with 3,4-dihydroxyphenylacetaldehyde formation. ( Bonnet, JJ; Costentin, J; Dingeval, MG; Janin, F; Legros, H, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Beaudry, A | 1 |
| Jacques-Ricard, S | 1 |
| Darracq, A | 1 |
| Sgarioto, N | 1 |
| Garcia, A | 1 |
| García, TR | 1 |
| Lemieux, W | 1 |
| Béland, K | 1 |
| Haddad, E | 1 |
| Cordeiro, P | 1 |
| Duval, M | 1 |
| McGraw, S | 1 |
| Richer, C | 1 |
| Caron, M | 1 |
| Marois, F | 1 |
| St-Onge, P | 1 |
| Sinnett, D | 1 |
| Banquy, X | 1 |
| Raynal, NJ | 1 |
| Legros, H | 1 |
| Dingeval, MG | 1 |
| Janin, F | 1 |
| Costentin, J | 1 |
| Bonnet, JJ | 1 |
| Posadas, I | 1 |
| Vellecco, V | 1 |
| Santos, P | 1 |
| Prieto-Lloret, J | 1 |
| Ceña, V | 1 |
| Gjessing, LR | 1 |
| Nishimura, T | 1 |
| Borud, O | 1 |
4 other studies available for disulfiram and Neuroblastoma
| Article | Year |
|---|---|
Repurposing disulfiram, an alcohol-abuse drug, in neuroblastoma causes KAT2A downregulation and in vivo activity with a water/oil emulsion.
Topics: Alcohol Deterrents; Animals; Cell Line, Tumor; Child; Disulfiram; Down-Regulation; Drug Repositionin | 2023 |
Toxicity of a treatment associating dopamine and disulfiram for catecholaminergic neuroblastoma SH-SY5Y cells: relationships with 3,4-dihydroxyphenylacetaldehyde formation.
Topics: 3,4-Dihydroxyphenylacetic Acid; Catecholamines; Cell Line, Tumor; Cell Survival; Disulfiram; Dopamin | 2004 |
Acetaminophen potentiates staurosporine-induced death in a human neuroblastoma cell line.
Topics: Acetaminophen; Acetylcysteine; Antineoplastic Agents; Apoptosis; Caspase 3; Cell Line, Tumor; Cell S | 2007 |
Studies on urinary phenolic compounds in man. I. Excretion of p-hydroxy-mandelic acid by man.
Topics: Amino Acid Metabolism, Inborn Errors; Chromatography; Disulfiram; Humans; In Vitro Techniques; Mande | 1965 |