guanethidine has been researched along with Neuroblastoma in 2 studies
Guanethidine: An antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves. It is believed to act mainly by preventing the release of norepinephrine at nerve endings and causes depletion of norepinephrine in peripheral sympathetic nerve terminals as well as in tissues.
guanethidine : A member of the class of guanidines in which one of the hydrogens of the amino group has been replaced by a 2-azocan-1-ylethyl group.
guanethidine sulfate : A organic sulfate salt composed of two molecules of guanethidine and one of sulfuric acid.
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Babich, JW | 1 |
| Graham, W | 1 |
| Fischman, AJ | 1 |
| Burnstock, G | 1 |
1 review available for guanethidine and Neuroblastoma
| Article | Year |
|---|---|
Do some sympathetic neurones synthesize and release both noradrenaline and acetylcholine?
Topics: Acetylcholine; Acetylcholinesterase; Animals; Biological Evolution; Cats; Cells, Cultured; Estrogens | 1978 |
1 other study available for guanethidine and Neuroblastoma
| Article | Year |
|---|---|
Effect of adrenergic receptor ligands on metaiodobenzylguanidine uptake and storage in neuroblastoma cells.
Topics: 3-Iodobenzylguanidine; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agon | 1997 |