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hydrogen sulfide and Neuroblastoma

hydrogen sulfide has been researched along with Neuroblastoma in 15 studies

Hydrogen Sulfide: A flammable, poisonous gas with a characteristic odor of rotten eggs. It is used in the manufacture of chemicals, in metallurgy, and as an analytical reagent. (From Merck Index, 11th ed)
hydrogen sulfide : A sulfur hydride consisting of a single sulfur atom bonded to two hydrogen atoms. A highly poisonous, flammable gas with a characteristic odour of rotten eggs, it is often produced by bacterial decomposition of organic matter in the absence of oxygen.
thiol : An organosulfur compound in which a thiol group, -SH, is attached to a carbon atom of any aliphatic or aromatic moiety.

Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)

Research Excerpts

ExcerptRelevanceReference
"Hydrogen sulfide (H2S) has been demonstrated to have various effects on mitochondrial function."5.46Hydrogen sulfide inhibits mitochondrial fission in neuroblastoma N2a cells through the Drp1/ERK1/2 signaling pathway. ( Gao, D; Liu, M; Qiao, P; Yan, Y; Zhang, H; Zhao, F, 2017)
"Hydrogen sulfide (H2S) has been recently categorized as a gasotransmitter, and it may be involved in the pathology of Alzheimer's disease."5.42Hydrogen sulfide-induced processing of the amyloid precursor protein in SH-SY5Y human neuroblastoma cells involves the PI3-K/Akt signaling pathway. ( Gao, Y; Qiao, PF; Yan, Y; Zhang, H; Zhao, FL, 2015)
" A modified biotin switch assay in SH-SY5Y human neuroblastoma cells revealed that PTEN is S-sulfhydrated endogenously."3.81Endogenous S-sulfhydration of PTEN helps protect against modification by nitric oxide. ( Ohno, K; Okuda, K; Uehara, T, 2015)
" The present study was undertaken to investigate the effects of H(2)S on cell injury induced by rotenone, a commonly used toxin in establishing in vivo and in vitro Parkinson's disease (PD) models, in human-derived dopaminergic neuroblastoma cell line (SH-SY5Y)."3.75Hydrogen sulfide inhibits rotenone-induced apoptosis via preservation of mitochondrial function. ( Bian, JS; Hu, LF; Lu, M; Wong, PT; Wu, ZY, 2009)
"Hydrogen sulfide (H2S) has been recently categorized as a gasotransmitter, and it may be involved in the pathology of Alzheimer's disease."1.42Hydrogen sulfide-induced processing of the amyloid precursor protein in SH-SY5Y human neuroblastoma cells involves the PI3-K/Akt signaling pathway. ( Gao, Y; Qiao, PF; Yan, Y; Zhang, H; Zhao, FL, 2015)
"Hydrogen sulfide (H2S) is a well-known cytotoxic gas."1.32The novel neuromodulator hydrogen sulfide: an endogenous peroxynitrite 'scavenger'? ( Armstrong, JS; Cheung, NS; Chu, SH; Halliwell, B; Jia-Ling, S; Moore, PK; Whiteman, M; Wong, BS, 2004)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (20.00)29.6817
2010's11 (73.33)24.3611
2020's1 (6.67)2.80

Authors

AuthorsStudies
Liu, L1
Wang, J1
Wang, H1
Qiao, P1
Zhao, F1
Liu, M1
Gao, D1
Zhang, H2
Yan, Y2
Shimoji, M1
Hara, H1
Kamiya, T1
Okuda, K2
Adachi, T1
Xin, L1
Junhua, W1
Long, L1
Jun, Y1
Yang, X1
Jurkowska, H1
Wróbel, M2
Szlęzak, D1
Jasek-Gajda, E1
Nagpure, BV1
Bian, JS4
Yang, HY1
Wu, ZY2
Gao, Y1
Zhao, FL1
Qiao, PF1
Ohno, K1
Uehara, T1
Bronowicka-Adamska, P1
Bentke, A1
Hu, LF2
Lu, M2
Wong, PT1
Schreier, SM1
Muellner, MK1
Steinkellner, H1
Hermann, M1
Esterbauer, H1
Exner, M1
Gmeiner, BM1
Kapiotis, S1
Laggner, H1
Choo, CH1
Tan, BH1
Hu, G1
Whiteman, M1
Armstrong, JS1
Chu, SH1
Jia-Ling, S1
Wong, BS1
Cheung, NS1
Halliwell, B1
Moore, PK1
Umemura, K1
Kimura, H1

Other Studies

15 other studies available for hydrogen sulfide and Neuroblastoma

ArticleYear
Hydrogen sulfide alleviates oxidative stress injury and reduces apoptosis induced by MPP
    Molecular and cellular biochemistry, 2020, Volume: 472, Issue:1-2

    Topics: 1-Methyl-4-phenylpyridinium; Apoptosis; Caspase 3; Cell Survival; Gasotransmitters; Herbicides; Huma

2020
Hydrogen sulfide inhibits mitochondrial fission in neuroblastoma N2a cells through the Drp1/ERK1/2 signaling pathway.
    Molecular medicine reports, 2017, Volume: 16, Issue:1

    Topics: Adenosine Triphosphate; Cell Line, Tumor; Cell Survival; Dynamins; Gene Expression Regulation, Neopl

2017
Hydrogen sulfide ameliorates zinc-induced cell death in neuroblastoma SH-SY5Y cells.
    Free radical research, 2017, Volume: 51, Issue:11-12

    Topics: Cell Death; Humans; Hydrogen Sulfide; Neuroblastoma; Zinc

2017
Exogenous Hydrogen Sulfide Protects SH-SY5Y Cells from OGD/RInduced Injury.
    Current molecular medicine, 2017, Volume: 17, Issue:8

    Topics: Cell Survival; Gasotransmitters; Glucose; Humans; Hydrogen Sulfide; Neuroblastoma; Neuroprotective A

2017
New aspects of antiproliferative activity of 4-hydroxybenzyl isothiocyanate, a natural H
    Amino acids, 2018, Volume: 50, Issue:6

    Topics: Cell Line, Tumor; Cell Proliferation; Humans; Hydrogen Sulfide; Isothiocyanates; Neuroblastoma; Oxid

2018
Hydrogen sulfide inhibits A2A adenosine receptor agonist induced β-amyloid production in SH-SY5Y neuroblastoma cells via a cAMP dependent pathway.
    PloS one, 2014, Volume: 9, Issue:2

    Topics: Adenosine A2 Receptor Agonists; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precu

2014
Hydrogen sulfide inhibits opioid withdrawal-induced pain sensitization in rats by down-regulation of spinal calcitonin gene-related peptide expression in the spine.
    The international journal of neuropsychopharmacology, 2014, Volume: 17, Issue:9

    Topics: Adenylyl Cyclases; Analgesics, Opioid; Animals; Calcitonin Gene-Related Peptide; Cell Line, Tumor; C

2014
Hydrogen sulfide-induced processing of the amyloid precursor protein in SH-SY5Y human neuroblastoma cells involves the PI3-K/Akt signaling pathway.
    Cellular and molecular neurobiology, 2015, Volume: 35, Issue:2

    Topics: ADAM Proteins; ADAM10 Protein; ADAM17 Protein; Amyloid beta-Protein Precursor; Amyloid Precursor Pro

2015
Endogenous S-sulfhydration of PTEN helps protect against modification by nitric oxide.
    Biochemical and biophysical research communications, 2015, Jan-02, Volume: 456, Issue:1

    Topics: Biotin; Cell Line, Tumor; Cystathionine beta-Synthase; Cysteine; Humans; Hydrogen Sulfide; Mutagenes

2015
Hydrogen sulfide generation from l-cysteine in the human glioblastoma-astrocytoma U-87 MG and neuroblastoma SHSY5Y cell lines.
    Acta biochimica Polonica, 2017, Volume: 64, Issue:1

    Topics: Astrocytoma; Cell Line, Tumor; Cystathionine; Cystathionine beta-Synthase; Cystathionine gamma-Lyase

2017
Hydrogen sulfide inhibits rotenone-induced apoptosis via preservation of mitochondrial function.
    Molecular pharmacology, 2009, Volume: 75, Issue:1

    Topics: Apoptosis; Benzimidazoles; Carbocyanines; Cell Line, Tumor; Cell Survival; Fluorescent Dyes; Formaza

2009
Hydrogen sulfide scavenges the cytotoxic lipid oxidation product 4-HNE.
    Neurotoxicity research, 2010, Volume: 17, Issue:3

    Topics: Air Pollutants; Aldehydes; Analysis of Variance; Cell Line, Tumor; Cell Survival; Dose-Response Rela

2010
Hydrogen sulfide regulates intracellular pH in rat primary cultured glia cells.
    Neuroscience research, 2010, Volume: 66, Issue:1

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Air Pollutants; Analysis of Variance; Animals; Ani

2010
The novel neuromodulator hydrogen sulfide: an endogenous peroxynitrite 'scavenger'?
    Journal of neurochemistry, 2004, Volume: 90, Issue:3

    Topics: Cell Line; Cell Survival; Dose-Response Relationship, Drug; Free Radical Scavengers; Humans; Hydroge

2004
Hydrogen sulfide enhances reducing activity in neurons: neurotrophic role of H2S in the brain?
    Antioxidants & redox signaling, 2007, Volume: 9, Issue:11

    Topics: Animals; Astrocytes; Brain; Cell Line, Tumor; Cells, Cultured; Chlorocebus aethiops; COS Cells; Dose

2007