azacitidine has been researched along with Neuroblastoma in 51 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (5.88) | 18.7374 |
| 1990's | 3 (5.88) | 18.2507 |
| 2000's | 18 (35.29) | 29.6817 |
| 2010's | 24 (47.06) | 24.3611 |
| 2020's | 3 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Balasubramanian, N; Banerjee, T; Kulkarni, PG; Manjrekar, R; Sakharkar, A | 1 |
| Kedarinath, K; Parks, GD; Shiffer, EM | 1 |
| Kavoosi, F; Sanaei, M | 1 |
| Fell, SM; Holmberg, J; Kogner, P; Li, S; Nyman, U; Schlisio, S; Shi, Y; Södersten, E; Surova, O; Toskas, K; Westerlund, I | 1 |
| Bannert, S; Bender, S; Benner, A; Dreidax, D; Duffy, D; Ehemann, V; Fischer, M; Henrich, KO; Lindner, S; Oakes, CC; Pfister, S; Saadati, M; Schröder, C; Schulte, JH; Schwarzl, T; Westermann, F | 1 |
| Deng, Y; Guo, X; Li, T; Liu, L; Lu, X; Yu, G; Zhang, Y | 1 |
| Cao, JL; Peng, YN; Tang, LH; Wang, Y; Yan, M; Yu, LN; Zhou, XL | 1 |
| Agrawal, R; Gomez-Pinilla, F; Tyagi, E; Ying, Z; Zhuang, Y | 1 |
| Bai, F; Cheerva, AC; Diller, L; George, RE; Krishnadas, DK; Lucas, KG; Shusterman, S; Sullivan, JE | 1 |
| Ackley, A; Burdach, J; Clemson, M; Hart, J; Lenox, A; Morris, KV; Saayman, S; Vadie, N; Vogt, PK | 1 |
| Ackermann, S; Berthold, F; Dreidax, D; Engesser, A; Fischer, M; Henrich, KO; Hero, B; Hertwig, F; Ikram, F; Kahlert, Y; Kocak, H; Nürnberg, P; Roels, F; Volland, R; Westermann, F | 1 |
| Ginat, R; Maman, S; Meshel, T; Naftali, O; Sagi-Assif, O; Witz, IP | 1 |
| Cheng, L; Hou, Y; Luo, T; Wang, F; Wang, H; Xu, J | 1 |
| Banelli, B; Barbagallo, C; Barbagallo, D; Di Mauro, S; Di Pietro, C; Magro, G; Maugeri, M; Purrello, F; Purrello, M; Ragusa, M; Romani, M | 1 |
| Brodeur, GM; Fujita, T; Gotoh, T; Igarashi, J; Kim, J; Kolla, V; London, WB; Manne, J; Maris, JM; Okawa, ER; Pawel, BR; White, PS; Zhao, H | 1 |
| Combaret, V; De Paepe, A; Hoebeeck, J; Hoyoux, C; Laureys, G; Michels, E; Pattyn, F; Speleman, F; Vandesompele, J; Vermeulen, J; Yigit, N | 1 |
| Chang, WS; Chen, PY; Lai, YK; Wu, CW | 1 |
| Allemanni, G; Banelli, B; Bonassi, S; Borzì, L; Brigati, C; Casciano, I; Di Vinci, A; Mazzocco, K; Romani, M; Scaruffi, P; Tonini, GP | 1 |
| Albasanz, JL; Barrachina, M; Buira, SP; Dentesano, G; Ferrer, I; Martín, M; Moreno, J | 1 |
| Chlenski, A; Cohn, SL; Godley, LA; Guerrero, LJ; Ostler, KR; Salwen, HR; Tian, Y; Yang, Q | 1 |
| Adamson, PC; Blaney, SM; Diller, L; Finkelstein, D; George, RE; Ingle, AM; Krailo, M; Lahti, JM; Neuberg, D; Reid, JM; Zhu, K | 1 |
| Alcock, L; Bryan, K; Buckley, PG; Das, S; Koster, J; Stallings, RL; Versteeg, R; Watters, KM | 1 |
| Chen, A; Elliott, E; Ezra-Nevo, G; Neufeld-Cohen, A; Regev, L | 1 |
| Bao, L; Dunham, K; Lucas, K | 1 |
| Börner, C; Höllt, V; Kraus, J; Martella, E | 1 |
| Brown, KW; Charlet, J; Diederich, M; Schnekenburger, M | 1 |
| Ausserlechner, MJ; Fiegl, H; Geiger, K; Hagenbuchner, J; Kiechl-Kohlendorfer, U; Meister, B; Müller, T; Obexer, P; Rupp, M; Sergi, C | 1 |
| Carén, H; Djos, A; Kogner, P; Martinsson, T | 1 |
| De Preter, K; Decock, A; Hoebeeck, J; Ladenstein, R; Laureys, G; Noguera, R; Ongenaert, M; Schulte, JH; Speleman, F; Stallings, RL; Van Criekinge, W; Van Damme, A; Van Maerken, T; Van Peer, G; Vandesompele, J; Vermeulen, J | 1 |
| Krishnadas, DK; Lucas, K; Shapiro, T | 1 |
| Beck, MN; Bourloud, KB; Gross, N; Mühlethaler, A; Yan, P | 1 |
| Hirschfeld, S; Ho, PT; Pazdur, R; Smith, M | 1 |
| Cappabianca, L; Farina, AR; Gulino, A; Mackay, AR; Mantovani, R; Tacconelli, A | 1 |
| Chlenski, A; Cohn, SL; Liu, S; Salwen, HR; Tian, Y; Weinstein, J; Yang, QW | 1 |
| Chlenski, A; Cohn, SL; Hasan, C; Kersey, D; Liu, S; Perlman, EJ; Salwen, HR; Tian, Y; Yang, Q | 1 |
| Carpentieri, D; Flake, AW; Hayashi, S; Ikegaki, N; Kim, DY; Kung, B; Riceberg, JS; Robinson, ME; Tang, XX; Titus, TB | 1 |
| Allemanni, G; Banelli, B; Brignole, C; Casciano, I; Croce, M; De Ambrosis, A; di Vinci, A; Ferrini, S; Gelvi, I; Pagnan, G; Ponzoni, M; Romani, M | 1 |
| Debatin, KM; Fulda, S | 1 |
| Cohn, SL; Cornell, J; McArdle, L; Nair, PN; Stallings, RL | 1 |
| Higashi, M; Kinoshita, Y; Maehara, Y; Souzaki, R; Suita, S; Taguchi, T; Tajiri, T; Tatsuta, K | 1 |
| Carén, H; Ejeskär, K; Fransson, S; Kogner, P; Martinsson, T | 1 |
| Clark, GJ; Ekström, TJ; Farnebo, F; Geli, J; Juhlin, C; Kiss, N; Kogner, P; Lanner, F; Larsson, C; Natalishvili, N | 1 |
| Augusti-Tocco, G; Bartolucci, S; Carpinelli, P; Granata, F; Rossi, M | 1 |
| Cashman, NR; Ledoux, S; Nalbantoglu, J | 1 |
| Adachi, J; Hanada, R; Hayashi, Y; Nakajima, T; Ogawa, Y; Takita, J; Tanaka, T; Yamaguchi, N; Yamamoto, K; Yokota, J | 1 |
| Fukunishi, Y; Hayashizaki, Y; Held, WA; Itoh, M; Kawai, J; Komatsu, S; Muramatsu, M; Okazaki, Y; Shibata, K; Tateno, M | 1 |
| Brodeur, GM; Eggert, A; Grotzer, MA; Ho, R; Ikegaki, N; Wiewrodt, BR; Zuzak, TJ | 1 |
| Agathanggelou, A; Astuti, D; Cummins, C; Dahia, P; Dallol, A; Eng, C; Honorio, S; Kogner, P; Latif, F; Maher, ER; Martinsson, T; Neumann, HP; Voutilainen, R | 1 |
| Biedler, JL; Melera, PW; Michitsch, RW | 1 |
| Savio, T; Schwab, ME | 1 |
| Augusti-Tocco, G; Bartolucci, S; Estenoz, M; Longo, A; Momparler, RL; Rossi, M; Santoro, B | 1 |
1 review(s) available for azacitidine and Neuroblastoma
| Article | Year |
|---|---|
Regulatory approvals of pediatric oncology drugs: previous experience and new initiatives.
Topics: Antineoplastic Agents; Azacitidine; Child; Child, Preschool; Drug Approval; Humans; Leukemia, Myeloid, Acute; Methotrexate; Neuroblastoma; Osteosarcoma; Pediatrics; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Teniposide; United States; United States Food and Drug Administration; Vindesine | 2003 |
2 trial(s) available for azacitidine and Neuroblastoma
| Article | Year |
|---|---|
A phase I trial combining decitabine/dendritic cell vaccine targeting MAGE-A1, MAGE-A3 and NY-ESO-1 for children with relapsed or therapy-refractory neuroblastoma and sarcoma.
Topics: Adolescent; Antigens, Neoplasm; Azacitidine; Cancer Vaccines; Cell Proliferation; Cells, Cultured; Child; Child, Preschool; Combined Modality Therapy; Decitabine; Dendritic Cells; Feasibility Studies; Female; Humans; Male; Melanoma-Specific Antigens; Membrane Proteins; Neoplasm Proteins; Neuroblastoma; Peptide Fragments; Recurrence; Sarcoma; T-Lymphocytes; Treatment Outcome | 2015 |
Phase I study of decitabine with doxorubicin and cyclophosphamide in children with neuroblastoma and other solid tumors: a Children's Oncology Group study.
Topics: Adolescent; Adult; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Caspase 8; Child; Child, Preschool; Cyclophosphamide; Decitabine; DNA Methylation; Doxorubicin; Female; Fetal Hemoglobin; Gene Expression Profiling; Humans; Infant; Male; Melanoma-Specific Antigens; Neoplasm Proteins; Neoplasms; Neuroblastoma | 2010 |
48 other study(ies) available for azacitidine and Neuroblastoma
| Article | Year |
|---|---|
DNA Methylation-Mediated Mfn2 Gene Regulation in the Brain: A Role in Brain Trauma-Induced Mitochondrial Dysfunction and Memory Deficits.
Topics: Animals; Azacitidine; Brain; Brain Injuries, Traumatic; DNA; DNA Methylation; Glutamates; Male; Memory Disorders; Mitochondria; Neuroblastoma; Rats; Rats, Wistar | 2023 |
DNA methyltransferase inhibitor 5-azacytidine enhances neuroblastoma cell lysis by an oncolytic parainfluenza virus.
Topics: Apoptosis; Azacitidine; Caspases; Cell Line, Tumor; Enzyme Inhibitors; Humans; Methyltransferases; Neuroblastoma; Virus Diseases | 2023 |
The Effect of 5-aza,2'-deoxyCytidine (5 AZA CdR or Decitabine) on Extrinsic, Intrinsic, and JAK/STAT Pathways in Neuroblastoma and Glioblastoma Cells Lines.
Topics: Azacitidine; Cell Line; Cell Line, Tumor; Decitabine; Deoxycytidine; DNA Methylation; Glioblastoma; Humans; Janus Kinases; Neuroblastoma; Signal Transduction; STAT Transcription Factors | 2023 |
Combined epigenetic and differentiation-based treatment inhibits neuroblastoma tumor growth and links HIF2α to tumor suppression.
Topics: Animals; Azacitidine; Basic Helix-Loop-Helix Transcription Factors; Cell Proliferation; Chemotherapy, Adjuvant; Decitabine; Female; Genetic Therapy; Hypoxia-Inducible Factor 1, alpha Subunit; Mice; Mice, Nude; Neuroblastoma; Tretinoin | 2017 |
p19-INK4d inhibits neuroblastoma cell growth, induces differentiation and is hypermethylated and downregulated in MYCN-amplified neuroblastomas.
Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Azacitidine; Cell Differentiation; Cell Line, Tumor; Child; Child, Preschool; Cyclin-Dependent Kinase Inhibitor p19; Decitabine; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Humans; Infant; Infant, Newborn; Male; N-Myc Proto-Oncogene Protein; Neoplasm Staging; Nervous System Neoplasms; Neuroblastoma; Neurons; Nuclear Proteins; Oncogene Proteins; Signal Transduction; Survival Analysis; Tretinoin | 2014 |
[Expression of neprilysin gene is associated with methylation and histone modification on promoter in mouse neuroblastoma Neuro-2a cells].
Topics: Acetylation; Animals; Azacitidine; Blotting, Western; Cell Line, Tumor; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Histones; Hydroxamic Acids; Mice; Neprilysin; Neuroblastoma; Promoter Regions, Genetic; Protein Binding; Reverse Transcriptase Polymerase Chain Reaction | 2014 |
Increased methylation of the MOR gene proximal promoter in primary sensory neurons plays a crucial role in the decreased analgesic effect of opioids in neuropathic pain.
Topics: Animals; Azacitidine; Cell Line, Tumor; CpG Islands; Decitabine; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ganglia, Spinal; Gene Expression Regulation; Hyperalgesia; Methylation; Mice; Morphine; Neuralgia; Neuroblastoma; Pain Measurement; Pain Threshold; Promoter Regions, Genetic; Receptors, Opioid, mu; Sensory Receptor Cells; Spinal Cord | 2014 |
Interactive actions of Bdnf methylation and cell metabolism for building neural resilience under the influence of diet.
Topics: Animals; Anxiety; Azacitidine; Brain; Brain-Derived Neurotrophic Factor; Cell Line, Tumor; Decitabine; Diet, Fat-Restricted; Disease Models, Animal; Enzyme Inhibitors; Fatty Acids, Omega-3; Female; Male; Maze Learning; Methylation; Mice; Neuroblastoma; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Transcription Factors | 2015 |
MYCNOS functions as an antisense RNA regulating MYCN.
Topics: Azacitidine; Carrier Proteins; Cell Line, Tumor; DNA Helicases; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; Hydroxamic Acids; Models, Genetic; N-Myc Proto-Oncogene Protein; Neuroblastoma; Nuclear Proteins; Oncogene Proteins; Poly-ADP-Ribose Binding Proteins; Promoter Regions, Genetic; Protein Isoforms; Protein Synthesis Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA Helicases; RNA Recognition Motif Proteins; RNA, Antisense | 2015 |
Transcription factor activating protein 2 beta (TFAP2B) mediates noradrenergic neuronal differentiation in neuroblastoma.
Topics: Adolescent; Adrenergic Neurons; Adult; Azacitidine; Cell Cycle; Cell Differentiation; Cell Line, Tumor; Child; Child, Preschool; CpG Islands; Decitabine; DNA Methylation; Dopamine beta-Hydroxylase; Down-Regulation; Gene Knockdown Techniques; Humans; Infant; Infant, Newborn; N-Myc Proto-Oncogene Protein; Neuroblastoma; Nuclear Proteins; Oncogene Proteins; Prognosis; Promoter Regions, Genetic; Repressor Proteins; RNA, Small Interfering; Transcription Factor AP-2; Tretinoin; Tyrosine 3-Monooxygenase; Up-Regulation; Young Adult | 2016 |
PHOX2B is a suppressor of neuroblastoma metastasis.
Topics: Animals; Azacitidine; Biomarkers, Tumor; DNA Methylation; Homeodomain Proteins; Humans; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm, Residual; Neuroblastoma; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Transcription Factors | 2016 |
Expression Profiles of SIRT1 and APP Genes in Human Neuroblastoma SK-N-SH Cells Treated with Two Epigenetic Agents.
Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Azacitidine; Cell Line, Tumor; Cell Survival; Decitabine; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Humans; Hydroxamic Acids; Neuroblastoma; Peptide Fragments; RNA, Messenger; Sirtuin 1; Time Factors | 2016 |
Altered expression of miRNAs and methylation of their promoters are correlated in neuroblastoma.
Topics: Animals; Azacitidine; Cell Line, Tumor; Cell Proliferation; Computational Biology; CpG Islands; Databases, Genetic; Decitabine; DNA Methylation; DNA Modification Methylases; Enzyme Inhibitors; Epigenesis, Genetic; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Genetic Predisposition to Disease; High-Throughput Nucleotide Sequencing; Humans; Kaplan-Meier Estimate; Mice; MicroRNAs; Neuroblastoma; Phenotype; Prognosis; Promoter Regions, Genetic; Protein Interaction Maps; Signal Transduction; Time Factors | 2016 |
CHD5, a tumor suppressor gene deleted from 1p36.31 in neuroblastomas.
Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Cell Line, Tumor; Chromosomes, Human, Pair 1; Colony-Forming Units Assay; Decitabine; DNA Helicases; DNA Methylation; DNA Mutational Analysis; DNA, Antisense; Down-Regulation; Gene Deletion; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Mice; Mice, Nude; Neoplastic Stem Cells; Nerve Tissue Proteins; Neuroblastoma; Predictive Value of Tests; Prognosis; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Risk Factors; RNA, Messenger; Transfection; Transplantation, Heterologous; Up-Regulation | 2008 |
Aberrant methylation of candidate tumor suppressor genes in neuroblastoma.
Topics: Azacitidine; Child; Child, Preschool; Decitabine; DNA Methylation; Epigenesis, Genetic; Genes, Tumor Suppressor; Genome; Humans; Hydroxamic Acids; Infant; Neuroblastoma; Polymerase Chain Reaction; RNA, Messenger | 2009 |
c-Myc regulates the coordinated transcription of brain disease-related PDCD10-SERPINI1 bidirectional gene pair.
Topics: Apoptosis Regulatory Proteins; Azacitidine; Cell Line, Tumor; Chromatin Immunoprecipitation; Decitabine; DNA Methylation; Electrophoretic Mobility Shift Assay; Enzyme Inhibitors; Glioblastoma; Humans; Membrane Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Neuroblastoma; Neuropeptides; Neuroserpin; Promoter Regions, Genetic; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myc; Serpins; Transcriptional Activation | 2009 |
Outcome prediction and risk assessment by quantitative pyrosequencing methylation analysis of the SFN gene in advanced stage, high-risk, neuroblastic tumor patients.
Topics: 14-3-3 Proteins; Azacitidine; Biomarkers, Tumor; Cell Line, Tumor; Child; Child, Preschool; Cohort Studies; CpG Islands; DNA Methylation; DNA, Neoplasm; Exonucleases; Exoribonucleases; Female; Ganglioneuroblastoma; Ganglioneuroma; Humans; Infant; Kaplan-Meier Estimate; Male; Neoplasm Proteins; Neuroblastoma; Prognosis; Proportional Hazards Models; Risk; Risk Assessment; Sequence Analysis, DNA; Soft Tissue Neoplasms; Survivors | 2010 |
DNA methylation regulates adenosine A(2A) receptor cell surface expression levels.
Topics: Azacitidine; Cell Line; Chromatin Immunoprecipitation; DNA Methylation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression Regulation; HeLa Cells; Humans; Immunoprecipitation; Methyl-CpG-Binding Protein 2; Neuroblastoma; Protein Binding; Radioligand Assay; Receptor, Adenosine A2A; Receptors, Cell Surface; RNA, Messenger; S-Adenosylmethionine; Time Factors; Triazines; Triazoles; Tritium | 2010 |
Epigenetic alterations differ in phenotypically distinct human neuroblastoma cell lines.
Topics: Acetylation; Azacitidine; Cell Line, Tumor; Cell Proliferation; Cell Shape; Chromatin Immunoprecipitation; Decitabine; DNA Methylation; DNA Modification Methylases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Genotype; Histone Deacetylase Inhibitors; Histones; Humans; Neuroblastoma; Phenotype; Polymerase Chain Reaction; Promoter Regions, Genetic; Thrombospondin 1; Transfection; Valproic Acid | 2010 |
Genome-wide DNA methylation analysis of neuroblastic tumors reveals clinically relevant epigenetic events and large-scale epigenomic alterations localized to telomeric regions.
Topics: Azacitidine; DNA Methylation; Epigenesis, Genetic; Gene Dosage; Gene Expression Regulation, Neoplastic; Genome; Humans; Neuroblastoma; Polymerase Chain Reaction; Telomere | 2011 |
Resilience to social stress coincides with functional DNA methylation of the Crf gene in adult mice.
Topics: Analysis of Variance; Animals; Antidepressive Agents, Tricyclic; Avoidance Learning; Azacitidine; Cell Line, Tumor; Corticotropin-Releasing Hormone; Cyclic AMP; Decitabine; DNA Methylation; Enzyme Inhibitors; Gene Expression Regulation; Genetic Vectors; Green Fluorescent Proteins; Imipramine; Injections, Intraventricular; Male; Mice; Mice, Inbred C57BL; Microdissection; Naphthalenes; Neuroblastoma; Neurons; Oxepins; Paraventricular Hypothalamic Nucleus; RNA Interference; RNA, Messenger; Stress, Psychological | 2010 |
MAGE-A1, MAGE-A3, and NY-ESO-1 can be upregulated on neuroblastoma cells to facilitate cytotoxic T lymphocyte-mediated tumor cell killing.
Topics: Antigens, Neoplasm; Azacitidine; Cell Line, Tumor; Decitabine; Humans; Interferon-gamma; Melanoma-Specific Antigens; Membrane Proteins; Neoplasm Proteins; Neuroblastoma; T-Lymphocytes, Cytotoxic; Up-Regulation | 2011 |
Regulation of opioid and cannabinoid receptor genes in human neuroblastoma and T cells by the epigenetic modifiers trichostatin A and 5-aza-2'-deoxycytidine.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Cell Line, Tumor; Decitabine; Epigenesis, Genetic; Humans; Hydroxamic Acids; Jurkat Cells; Neuroblastoma; Real-Time Polymerase Chain Reaction; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Receptors, Opioid, mu; T-Lymphocytes | 2012 |
DNA demethylation increases sensitivity of neuroblastoma cells to chemotherapeutic drugs.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Azacitidine; Cell Culture Techniques; Cell Line, Tumor; Cell Survival; Decitabine; DNA Methylation; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Synergism; Epigenesis, Genetic; Humans; Neuroblastoma; Reverse Transcriptase Polymerase Chain Reaction | 2012 |
FOXO3/FKHRL1 is activated by 5-aza-2-deoxycytidine and induces silenced caspase-8 in neuroblastoma.
Topics: Apoptosis; Ataxia Telangiectasia Mutated Proteins; Azacitidine; Base Sequence; Caspase 8; Cell Cycle Proteins; Cell Line, Tumor; Cell Nucleus; Cyclic AMP Response Element-Binding Protein; Decitabine; DNA Methylation; DNA-Binding Proteins; Drug Screening Assays, Antitumor; Enzyme Activation; Enzyme Induction; Forkhead Box Protein O3; Forkhead Transcription Factors; Gene Expression Regulation, Neoplastic; Gene Silencing; HEK293 Cells; Humans; Neuroblastoma; Phosphorylation; Protein Serine-Threonine Kinases; Signal Transduction; TNF-Related Apoptosis-Inducing Ligand; Tumor Suppressor Proteins | 2012 |
The RASSF gene family members RASSF5, RASSF6 and RASSF7 show frequent DNA methylation in neuroblastoma.
Topics: Adaptor Proteins, Signal Transducing; Apoptosis Regulatory Proteins; Azacitidine; Base Sequence; Cell Line, Tumor; Child, Preschool; CpG Islands; DNA Methylation; Epigenesis, Genetic; Female; Gene Amplification; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Infant; Male; Monomeric GTP-Binding Proteins; N-Myc Proto-Oncogene Protein; Neoplasm Staging; Neuroblastoma; Nuclear Proteins; Oncogene Proteins; Prognosis; Transcription Factors | 2012 |
Genome-wide promoter methylation analysis in neuroblastoma identifies prognostic methylation biomarkers.
Topics: Azacitidine; Biomarkers, Tumor; Cell Line, Tumor; Chromogranins; Databases, Genetic; Decitabine; DNA Methylation; Epigenomics; Gene Expression Regulation, Neoplastic; Genome, Human; GTP-Binding Protein alpha Subunits, Gs; HCT116 Cells; High-Throughput Nucleotide Sequencing; Humans; Neuroblastoma; Promoter Regions, Genetic; Risk Factors; Sequence Analysis, DNA; Survival Analysis | 2012 |
Complete remission following decitabine/dendritic cell vaccine for relapsed neuroblastoma.
Topics: Azacitidine; Cancer Vaccines; Child; Decitabine; Dendritic Cells; Hematopoietic Stem Cell Transplantation; Humans; Male; Neuroblastoma; Recurrence; Remission Induction | 2013 |
Hypermethylation-mediated regulation of CD44 gene expression in human neuroblastoma.
Topics: Azacitidine; Bone Marrow Neoplasms; CpG Islands; Decitabine; DNA Methylation; DNA Modification Methylases; Exons; Gene Amplification; Gene Expression Regulation; Gene Silencing; Humans; Hyaluronan Receptors; Immunohistochemistry; N-Myc Proto-Oncogene Protein; Neoplasm Staging; Neuroblastoma; Nuclear Proteins; Oncogene Proteins; Promoter Regions, Genetic; Tumor Cells, Cultured | 2003 |
Reconstitution of TIMP-2 expression in SH-SY5Y neuroblastoma cells by 5-azacytidine is mediated transcriptionally by NF-Y through an inverted CCAAT site.
Topics: Antimetabolites, Antineoplastic; Azacitidine; CCAAT-Binding Factor; Child; DNA Methylation; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Genes, Regulator; Humans; Methyltransferases; Mutation; Neuroblastoma; Promoter Regions, Genetic; Protein Binding; Repressor Proteins; Tissue Inhibitor of Metalloproteinase-2; Transcription, Genetic; Tumor Cells, Cultured | 2003 |
Methylation-associated silencing of the thrombospondin-1 gene in human neuroblastoma.
Topics: Animals; Azacitidine; Cell Division; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Neuroblastoma; Promoter Regions, Genetic; Thrombospondin 1; Transcription, Genetic; Transplantation, Heterologous | 2003 |
Methylation-associated silencing of the heat shock protein 47 gene in human neuroblastoma.
Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Cell Line, Tumor; Collagen Type I; Collagen Type IV; Decitabine; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Heat-Shock Proteins; HSP47 Heat-Shock Proteins; Humans; Mice; Mice, Nude; Neuroblastoma; Oligonucleotide Array Sequence Analysis; Promoter Regions, Genetic; Up-Regulation | 2004 |
Favorable neuroblastoma genes and molecular therapeutics of neuroblastoma.
Topics: Animals; Antineoplastic Agents; Apoptosis; Azacitidine; Boronic Acids; Caspases; Decitabine; DNA; DNA Methylation; DNA Modification Methylases; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Mice; Mice, Nude; Mice, SCID; Neoplasm Proteins; Neuroblastoma; Phenylbutyrates; Proteasome Inhibitors; Transplantation, Heterologous; Tumor Cells, Cultured | 2004 |
Caspase-8 gene expression in neuroblastoma.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Caspase 8; Caspases; Cell Line, Tumor; CpG Islands; DNA; DNA Methylation; Gene Expression Regulation, Neoplastic; Humans; Interferon-gamma; Neuroblastoma; Promoter Regions, Genetic; RNA; Tretinoin | 2004 |
5-Aza-2'-deoxycytidine and IFN-gamma cooperate to sensitize for TRAIL-induced apoptosis by upregulating caspase-8.
Topics: Apoptosis; Apoptosis Regulatory Proteins; Azacitidine; Caspase 8; Caspases; Cell Line, Tumor; Cell Survival; Cerebellar Neoplasms; Decitabine; Gene Expression Regulation, Enzymologic; Humans; Interferon-gamma; Medulloblastoma; Membrane Glycoproteins; Neuroblastoma; Recombinant Proteins; TNF-Related Apoptosis-Inducing Ligand; Tumor Necrosis Factor-alpha | 2006 |
High-resolution analysis of 3p deletion in neuroblastoma and differential methylation of the SEMA3B tumor suppressor gene.
Topics: Adolescent; Antineoplastic Agents; Azacitidine; Base Sequence; Cell Differentiation; Cell Line; Cell Line, Tumor; Child; Child, Preschool; Chromosome Breakage; Chromosome Deletion; Chromosomes, Human, Pair 3; CpG Islands; Decitabine; DNA Methylation; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Infant; Membrane Glycoproteins; Molecular Sequence Data; Neuroblastoma; Nucleic Acid Hybridization; Reverse Transcriptase Polymerase Chain Reaction; Semaphorins; Tretinoin | 2007 |
High expressions of neuronatin isoforms in favorable neuroblastoma.
Topics: Azacitidine; Cell Line, Tumor; Decitabine; DNA Methylation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Genomic Imprinting; Humans; Infant; Membrane Proteins; Nerve Tissue Proteins; Neuroblastoma; Oligonucleotide Array Sequence Analysis; Prognosis; Protein Isoforms; RNA, Messenger; Up-Regulation | 2007 |
Genetic and epigenetic changes in the common 1p36 deletion in neuroblastoma tumours.
Topics: Adaptor Proteins, Signal Transducing; Azacitidine; Cell Line, Tumor; Chromosome Deletion; Chromosomes, Human, Pair 1; Class I Phosphatidylinositol 3-Kinases; Decitabine; DNA Methylation; DNA Mutational Analysis; DNA-Binding Proteins; DNA, Neoplasm; Exons; Genetic Variation; Histones; Humans; Hydroxamic Acids; Mutation; Neuroblastoma; Phosphatidylinositol 3-Kinases; Polymorphism, Genetic; Retinol-Binding Proteins, Cellular; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription Factors; Transcription, Genetic; Tumor Suppressor Proteins; Up-Regulation | 2007 |
Assessment of NORE1A as a putative tumor suppressor in human neuroblastoma.
Topics: Adaptor Proteins, Signal Transducing; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Azacitidine; Bromodeoxyuridine; Cell Line, Tumor; DNA Methylation; Down-Regulation; Ganglioneuroma; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Hydroxamic Acids; Monomeric GTP-Binding Proteins; Neuroblastoma; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2008 |
Antiproliferative effects and DNA hypomethylation by 5-aza-2'-deoxycytidine in human neuroblastoma cell lines.
Topics: Antigens, Differentiation; Antineoplastic Agents; Azacitidine; Brain Neoplasms; Cell Division; Decitabine; Deoxycytidine; Deoxycytidine Kinase; DNA-Cytosine Methylases; DNA, Neoplasm; Humans; Methylation; Neuroblastoma; Tumor Cells, Cultured | 1993 |
Amyloid precursor protein gene expression in neural cell lines: influence of DNA cytosine methylation.
Topics: Amyloid beta-Protein Precursor; Animals; Azacitidine; Cell Line; Cytosine; DNA, Neoplasm; Gene Expression; Gene Expression Regulation, Neoplastic; Methylation; Mice; Neuroblastoma; Restriction Mapping; RNA, Messenger; RNA, Ribosomal, 28S | 1994 |
The p16 (CDKN2A) gene is involved in the growth of neuroblastoma cells and its expression is associated with prognosis of neuroblastoma patients.
Topics: Azacitidine; Cell Division; Cyclin-Dependent Kinase Inhibitor p16; Decitabine; DNA Modification Methylases; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; Neuroblastoma; Prognosis; Tumor Cells, Cultured | 1998 |
Identification of a novel member of the snail/Gfi-1 repressor family, mlt 1, which is methylated and silenced in liver tumors of SV40 T antigen transgenic mice.
Topics: Amino Acid Sequence; Animals; Antigens, Polyomavirus Transforming; Antimetabolites, Antineoplastic; Azacitidine; Base Sequence; Decitabine; DNA Methylation; DNA-Binding Proteins; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Genome, Human; Humans; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Molecular Sequence Data; Neuroblastoma; Open Reading Frames; Promoter Regions, Genetic; Repressor Proteins; RNA, Messenger; Snail Family Transcription Factors; Transcription Factors; Zinc Fingers | 2001 |
Resistance to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in neuroblastoma cells correlates with a loss of caspase-8 expression.
Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Apoptosis Regulatory Proteins; Azacitidine; Caspase 10; Caspase 8; Caspase 9; Caspase Inhibitors; Caspases; Cysteine Proteinase Inhibitors; Decitabine; Dose-Response Relationship, Drug; Enzyme Inhibitors; GPI-Linked Proteins; Humans; Jurkat Cells; Membrane Glycoproteins; Methylation; Neuroblastoma; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Member 10c; Reverse Transcriptase Polymerase Chain Reaction; TNF-Related Apoptosis-Inducing Ligand; Tumor Necrosis Factor Decoy Receptors; Tumor Necrosis Factor-alpha | 2001 |
RASSF1A promoter region CpG island hypermethylation in phaeochromocytomas and neuroblastoma tumours.
Topics: Adrenal Gland Neoplasms; Alleles; Antimetabolites, Antineoplastic; Azacitidine; Base Sequence; Caspase 8; Caspase 9; Caspases; Chromosomes, Human, Pair 3; CpG Islands; DNA Methylation; DNA Mutational Analysis; Gene Deletion; Genes, Tumor Suppressor; Humans; Loss of Heterozygosity; Microsatellite Repeats; Molecular Sequence Data; Mutation; Neoplasm Proteins; Neuroblastoma; Phenotype; Pheochromocytoma; Prognosis; Promoter Regions, Genetic; Tumor Suppressor Proteins | 2001 |
Modulation of N-myc expression, but not tumorigenicity, accompanies phenotypic conversion of neuroblastoma cells in prolonged culture.
Topics: Azacitidine; Cell Line; Cell Transformation, Neoplastic; Gene Amplification; Gene Expression Regulation; Humans; Methylation; Neuroblastoma; Oncogenes; Phenotype; Time Factors; Tumor Cells, Cultured | 1988 |
Rat CNS white matter, but not gray matter, is nonpermissive for neuronal cell adhesion and fiber outgrowth.
Topics: Animals; Antibodies; Azacitidine; Cell Adhesion; Central Nervous System; Nerve Fibers; Neuroblastoma; Neurons; Periaqueductal Gray; Peripheral Nerves; Rats; Rats, Inbred Lew; Trout; Tumor Cells, Cultured | 1989 |
5-Aza-2'-deoxycytidine as inducer of differentiation and growth inhibition in mouse neuroblastoma cells.
Topics: Acetylcholinesterase; Animals; Azacitidine; Cell Differentiation; Cell Division; Cell Survival; Decitabine; DNA; Methylation; Mice; Neuroblastoma; Tumor Cells, Cultured | 1989 |