Page last updated: 2024-10-30

labetalol and Neuroblastoma

labetalol has been researched along with Neuroblastoma in 4 studies

Labetalol: A salicylamide derivative that is a non-cardioselective blocker of BETA-ADRENERGIC RECEPTORS and ALPHA-1 ADRENERGIC RECEPTORS.
labetalol : A diastereoisomeric mixture of approximately equal amounts of all four possible stereoisomers ((R,S)-labetolol, (S,R)-labetolol, (S,S)-labetalol and (R,R)-labetalol). It is an adrenergic antagonist used to treat high blood pressure.
2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl}benzamide : A member of the class of benzamides that is benzamide substituted by a hydroxy group at position 2 and by a 1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl group at position 5.

Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)

Research Excerpts

ExcerptRelevanceReference
"Preoperative alpha- and beta-adrenergic receptor block with phenoxybenzamine and labetalol, the intraoperative course of a 4-month-old infant with neuroblastoma and elevated catecholamines causing sweating, hypertension, and tachycardia, are presented."3.75Catecholamine-secreting neuroblastoma in a 4-month-old infant: perioperative management. ( Hernandez, MR; Seefelder, C; Shamberger, RC, 2009)
"Neonatal hypertension is increasingly recognized as dramatic improvements in neonatal intensive care, advancements in our understanding of neonatal physiology, and implementation of new therapies have led to improved survival of premature infants."2.61Neonatal hypertension: cases, causes, and clinical approach. ( Flynn, JT; Starr, MC, 2019)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's1 (25.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Starr, MC1
Flynn, JT1
Hernandez, MR1
Shamberger, RC2
Seefelder, C2
Pappas, L1
Plowman, PN1

Reviews

1 review available for labetalol and Neuroblastoma

ArticleYear
Neonatal hypertension: cases, causes, and clinical approach.
    Pediatric nephrology (Berlin, Germany), 2019, Volume: 34, Issue:5

    Topics: Administration, Intravenous; Antihypertensive Agents; Birth Weight; Blood Pressure; Blood Pressure D

2019

Other Studies

3 other studies available for labetalol and Neuroblastoma

ArticleYear
Catecholamine-secreting neuroblastoma in a 4-month-old infant: perioperative management.
    Journal of clinical anesthesia, 2009, Volume: 21, Issue:1

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Catecholamines; Female; Humans; Hypertens

2009
Giant, dopamine secreting thoracoabdominal neuroblastoma in a 2-year-old: rapid preoperative blockade with labetalol.
    Journal of pediatric hematology/oncology, 2010, Volume: 32, Issue:2

    Topics: Abdominal Neoplasms; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Antihypertensive Age

2010
Positive MIBG scanning at the time of relapse in neuroblastoma which was MIBG negative at diagnosis.
    The British journal of radiology, 1997, Volume: 70, Issue:837

    Topics: 3-Iodobenzylguanidine; Antihypertensive Agents; Drug Interactions; False Negative Reactions; Humans;

1997