Page last updated: 2024-10-17

cytosine and Neuroblastoma

cytosine has been researched along with Neuroblastoma in 7 studies

Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)

Research Excerpts

ExcerptRelevanceReference
"Neuroblastomas are childhood tumors with frequent fatal relapses after induction treatment, which is related to tumor evolution with additional genomic events."5.62Defects in 8-oxo-guanine repair pathway cause high frequency of C > A substitutions in neuroblastoma. ( Dolman, MEM; Drost, J; Ebus, ME; Essing, AHW; Hakkert, A; Helleday, T; Hoyng, LL; Koopmans, B; Koster, J; Molenaar, JJ; Molenaar, P; Oka, R; Schild, L; van Boxtel, R; van den Boogaard, ML; van Gerven, MR; Versteeg, R; Zwijnenburg, DA, 2021)
"Neuroblastomas are childhood tumors with frequent fatal relapses after induction treatment, which is related to tumor evolution with additional genomic events."1.62Defects in 8-oxo-guanine repair pathway cause high frequency of C > A substitutions in neuroblastoma. ( Dolman, MEM; Drost, J; Ebus, ME; Essing, AHW; Hakkert, A; Helleday, T; Hoyng, LL; Koopmans, B; Koster, J; Molenaar, JJ; Molenaar, P; Oka, R; Schild, L; van Boxtel, R; van den Boogaard, ML; van Gerven, MR; Versteeg, R; Zwijnenburg, DA, 2021)
"The results show that while tumors of the same histological type had similar 5-methylcytosine values, discrepancies existed between values obtained for fresh tumors and their corresponding cell lines."1.27Variable 5-methylcytosine levels in human tumor cell lines and fresh pediatric tumor explants. ( Bogenmann, E; Flatau, E; Jones, PA, 1983)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19903 (42.86)18.7374
1990's2 (28.57)18.2507
2000's0 (0.00)29.6817
2010's1 (14.29)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
van den Boogaard, ML1
Oka, R1
Hakkert, A1
Schild, L1
Ebus, ME1
van Gerven, MR1
Zwijnenburg, DA1
Molenaar, P1
Hoyng, LL1
Dolman, MEM1
Essing, AHW1
Koopmans, B1
Helleday, T1
Drost, J1
van Boxtel, R1
Versteeg, R1
Koster, J1
Molenaar, JJ1
Mariani, CJ1
Vasanthakumar, A1
Madzo, J1
Yesilkanal, A1
Bhagat, T1
Yu, Y1
Bhattacharyya, S1
Wenger, RH1
Cohn, SL1
Nanduri, J1
Verma, A1
Prabhakar, NR1
Godley, LA1
Oku, T1
Imanishi, J1
Kishida, T1
Flatau, E1
Bogenmann, E1
Jones, PA1
Ledoux, S1
Nalbantoglu, J1
Cashman, NR1
Puttfarcken, PS1
Manelli, AM1
Arneric, SP1
Donnelly-Roberts, DL1
Kappler, JW1

Other Studies

7 other studies available for cytosine and Neuroblastoma

ArticleYear
Defects in 8-oxo-guanine repair pathway cause high frequency of C > A substitutions in neuroblastoma.
    Proceedings of the National Academy of Sciences of the United States of America, 2021, 09-07, Volume: 118, Issue:36

    Topics: Adenine; Child; Cytosine; DNA Damage; DNA Glycosylases; DNA Repair; Female; Guanine; Guanosine; Huma

2021
TET1-mediated hydroxymethylation facilitates hypoxic gene induction in neuroblastoma.
    Cell reports, 2014, Jun-12, Volume: 7, Issue:5

    Topics: 5-Methylcytosine; Cell Hypoxia; Cell Line, Tumor; Cytosine; DNA Methylation; DNA-Binding Proteins; E

2014
Interferon counteracts pyrimidinone-induced hyporeactivity and the combined treatment has antitumor effect in mice.
    Gan, 1984, Volume: 75, Issue:7

    Topics: Animals; Cytosine; Drug Administration Schedule; Drug Therapy, Combination; Female; Interferon Induc

1984
Variable 5-methylcytosine levels in human tumor cell lines and fresh pediatric tumor explants.
    Cancer research, 1983, Volume: 43, Issue:10

    Topics: 5-Methylcytosine; Autoradiography; Cell Line; Cerebellar Neoplasms; Cytosine; DNA; Fibroblasts; Huma

1983
Amyloid precursor protein gene expression in neural cell lines: influence of DNA cytosine methylation.
    Brain research. Molecular brain research, 1994, Volume: 24, Issue:1-4

    Topics: Amyloid beta-Protein Precursor; Animals; Azacitidine; Cell Line; Cytosine; DNA, Neoplasm; Gene Expre

1994
Evidence for nicotinic receptors potentially modulating nociceptive transmission at the level of the primary sensory neuron: studies with F11 cells.
    Journal of neurochemistry, 1997, Volume: 69, Issue:3

    Topics: Analgesics, Non-Narcotic; Analysis of Variance; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cy

1997
The 5-methylcytosine content of DNA: tissue specificity.
    Journal of cellular physiology, 1971, Volume: 78, Issue:1

    Topics: Adrenal Gland Neoplasms; Animals; Carbon Isotopes; Cell Line; Chick Embryo; Clone Cells; Culture Tec

1971