| Condition | Indicated | Relationship Strength | Studies | Trials |
|---|
Innate Inflammatory Response
[description not available] | 0 | 3.06 | 4 | 0 |
Inflammation
A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function. | 0 | 8.06 | 4 | 0 |
Plasmodium falciparum Malaria
[description not available] | 0 | 2.1 | 1 | 0 |
Malaria, Falciparum
Malaria caused by PLASMODIUM FALCIPARUM. This is the severest form of malaria and is associated with the highest levels of parasites in the blood. This disease is characterized by irregularly recurring febrile paroxysms that in extreme cases occur with acute cerebral, renal, or gastrointestinal manifestations. | 0 | 2.1 | 1 | 0 |
Carcinogenesis
The origin, production or development of cancer through genotypic and phenotypic changes which upset the normal balance between cell proliferation and cell death. Carcinogenesis generally requires a constellation of steps, which may occur quickly or over a period of many years. | 0 | 7.72 | 2 | 0 |
Colorectal Cancer
[description not available] | 0 | 2.72 | 2 | 0 |
Colorectal Neoplasms
Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI. | 0 | 2.72 | 2 | 0 |
Aging
The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time. | 0 | 2.31 | 1 | 0 |
Diabetes Mellitus
A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE. | 0 | 3.68 | 2 | 0 |
Age-Related Osteoporosis
[description not available] | 0 | 2.82 | 2 | 0 |
Osteoporosis
Reduction of bone mass without alteration in the composition of bone, leading to fractures. Primary osteoporosis can be of two major types: postmenopausal osteoporosis (OSTEOPOROSIS, POSTMENOPAUSAL) and age-related or senile osteoporosis. | 0 | 7.82 | 2 | 0 |
Benign Neoplasms, Brain
[description not available] | 0 | 2.6 | 1 | 0 |
Astrocytoma, Grade IV
[description not available] | 0 | 2.6 | 1 | 0 |
Brain Neoplasms
Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain. | 0 | 2.6 | 1 | 0 |
Glioblastoma
A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures. | 0 | 7.6 | 1 | 0 |
Neuroblastoma
A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51) | 0 | 7.6 | 1 | 0 |
Cancer of Colon
[description not available] | 0 | 2.59 | 2 | 0 |
Colonic Neoplasms
Tumors or cancer of the COLON. | 0 | 2.59 | 2 | 0 |
Infections, Helicobacter
[description not available] | 0 | 2.6 | 1 | 0 |
Helicobacter Infections
Infections with organisms of the genus HELICOBACTER, particularly, in humans, HELICOBACTER PYLORI. The clinical manifestations are focused in the stomach, usually the gastric mucosa and antrum, and the upper duodenum. This infection plays a major role in the pathogenesis of type B gastritis and peptic ulcer disease. | 0 | 2.6 | 1 | 0 |
Arrhythmia
[description not available] | 0 | 7.25 | 1 | 0 |
Cardiovascular Stroke
[description not available] | 0 | 2.25 | 1 | 0 |
Arrhythmias, Cardiac
Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction. | 0 | 2.25 | 1 | 0 |
Myocardial Infarction
NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION). | 0 | 7.25 | 1 | 0 |
Insulin Sensitivity
[description not available] | 0 | 2.25 | 1 | 0 |
Insulin Resistance
Diminished effectiveness of INSULIN in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent HYPERGLYCEMIA or KETOSIS. | 0 | 2.25 | 1 | 0 |
Body Weight
The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms. | 0 | 3.55 | 2 | 0 |
Disbacteriosis
[description not available] | 0 | 2.31 | 1 | 0 |
Obesity
A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY). | 0 | 3.55 | 2 | 0 |
Leucocythaemia
[description not available] | 0 | 2.31 | 1 | 0 |
Leukemia
A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006) | 0 | 2.31 | 1 | 0 |
Cardiometabolic Syndrome
A cluster of symptoms that are risk factors for CARDIOVASCULAR DISEASES and TYPE 2 DIABETES MELLITUS. The major components not only include metabolic dysfunctions of METABOLIC SYNDROME but also HYPERTENSION, and ABDOMINAL OBESITY. | 0 | 3.09 | 1 | 0 |
Overweight
A status with BODY WEIGHT that is above certain standards. In the scale of BODY MASS INDEX, overweight is defined as having a BMI of 25.0-29.9 kg/m2. Overweight may or may not be due to increases in body fat (ADIPOSE TISSUE), hence overweight does not equal over fat. | 0 | 4.9 | 2 | 1 |
Cardiovascular Diseases
Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM. | 0 | 5.14 | 3 | 1 |
Metabolic Syndrome
A cluster of symptoms that are risk factors for CARDIOVASCULAR DISEASES and TYPE 2 DIABETES MELLITUS. The major components of metabolic syndrome include ABDOMINAL OBESITY; atherogenic DYSLIPIDEMIA; HYPERTENSION; HYPERGLYCEMIA; INSULIN RESISTANCE; a proinflammatory state; and a prothrombotic (THROMBOSIS) state. | 0 | 3.09 | 1 | 0 |
Alloxan Diabetes
[description not available] | 0 | 2.15 | 1 | 0 |
Cardiac Diseases
[description not available] | 0 | 2.15 | 1 | 0 |
Hyperglycemia, Postprandial
Abnormally high BLOOD GLUCOSE level after a meal. | 0 | 2.15 | 1 | 0 |
Heart Diseases
Pathological conditions involving the HEART including its structural and functional abnormalities. | 0 | 2.15 | 1 | 0 |
Hyperglycemia
Abnormally high BLOOD GLUCOSE level. | 0 | 2.15 | 1 | 0 |
B16 Melanoma
[description not available] | 0 | 7.15 | 1 | 0 |
Wasting Disease
[description not available] | 0 | 3.09 | 1 | 0 |
Atrophy, Muscle
[description not available] | 0 | 3.48 | 2 | 0 |
Cachexia
General ill health, malnutrition, and weight loss, usually associated with chronic disease. | 0 | 3.09 | 1 | 0 |
Muscular Atrophy
Derangement in size and number of muscle fibers occurring with aging, reduction in blood supply, or following immobilization, prolonged weightlessness, malnutrition, and particularly in denervation. | 0 | 3.48 | 2 | 0 |
Breast Cancer
[description not available] | 0 | 2.17 | 1 | 0 |
Breast Neoplasms
Tumors or cancer of the human BREAST. | 0 | 2.17 | 1 | 0 |
Atherogenesis
[description not available] | 0 | 2.57 | 2 | 0 |
Atheroma
[description not available] | 0 | 2.21 | 1 | 0 |
Atherosclerosis
A thickening and loss of elasticity of the walls of ARTERIES that occurs with formation of ATHEROSCLEROTIC PLAQUES within the ARTERIAL INTIMA. | 0 | 7.57 | 2 | 0 |
Hepatocellular Carcinoma
[description not available] | 0 | 7.21 | 1 | 0 |
Cancer of Liver
[description not available] | 0 | 2.21 | 1 | 0 |
Carcinoma, Hepatocellular
A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested. | 0 | 2.21 | 1 | 0 |
Liver Neoplasms
Tumors or cancer of the LIVER. | 0 | 2.21 | 1 | 0 |
Bacteremia
The presence of viable bacteria circulating in the blood. Fever, chills, tachycardia, and tachypnea are common acute manifestations of bacteremia. The majority of cases are seen in already hospitalized patients, most of whom have underlying diseases or procedures which render their bloodstreams susceptible to invasion. | 0 | 2.1 | 1 | 0 |
Cancer of Prostate
[description not available] | 0 | 2.1 | 1 | 0 |
Prostatic Neoplasms
Tumors or cancer of the PROSTATE. | 0 | 2.1 | 1 | 0 |
Liver Dysfunction
[description not available] | 0 | 2.11 | 1 | 0 |
Liver Diseases
Pathological processes of the LIVER. | 0 | 2.11 | 1 | 0 |
Acute Confusional Senile Dementia
[description not available] | 0 | 2.13 | 1 | 0 |
Disease Models, Animal
Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases. | 0 | 2.13 | 1 | 0 |
Alzheimer Disease
A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57) | 0 | 2.13 | 1 | 0 |
Urinary Tract Infections
Inflammatory responses of the epithelium of the URINARY TRACT to microbial invasions. They are often bacterial infections with associated BACTERIURIA and PYURIA. | 0 | 2.15 | 1 | 0 |