guaiacol has been researched along with Neuroblastoma in 4 studies
Guaiacol: An agent thought to have disinfectant properties and used as an expectorant. (From Martindale, The Extra Pharmacopoeia, 30th ed, p747)
methylcatechol : Any member of the class of catechols carrying one or more methyl substituents.
guaiacol : A monomethoxybenzene that consists of phenol with a methoxy substituent at the ortho position.
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Consequently, this reaction has long been used to measure tyrosine in tyrosinosis and tyrosinemia, homovanillic acid in neuroblastoma, and 5-hydroxy-3-indoleacetic acid in the carcinoid tumor." | 3.66 | The chemical basis and specificity of the nitrosonaphthol reaction. ( Knight, JA; Robertson, G; Wu, JT, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Coccini, T | 1 |
| Vecchio, S | 1 |
| Crevani, M | 1 |
| De Simone, U | 1 |
| Knight, JA | 1 |
| Robertson, G | 1 |
| Wu, JT | 1 |
| Vauquelin, G | 1 |
| Verheyden, R | 1 |
| Ebinger, G | 1 |
| Strosberg, AD | 1 |
| Rogers, LE | 1 |
| Lyon, GM | 1 |
| Porter, FS | 1 |
4 other studies available for guaiacol and Neuroblastoma
| Article | Year |
|---|---|
Cytotoxic Effects of 3,4-Catechol-PV (One Major MDPV Metabolite) on Human Dopaminergic SH-SY5Y Cells.
Topics: Antineoplastic Agents; Benzodioxoles; Caspase 3; Cell Differentiation; Cell Line, Tumor; Cell Size; | 2019 |
The chemical basis and specificity of the nitrosonaphthol reaction.
Topics: Amino Acid Metabolism, Inborn Errors; Carcinoid Tumor; Chemical Phenomena; Chemistry; Guaiacol; Homo | 1983 |
Diazotization of catecholamines and their analogs and metabolites for urinary screening tests: chemical aspects.
Topics: Aniline Compounds; Catecholamines; Chemical Phenomena; Chemistry; Diazonium Compounds; Guaiacol; Hyd | 1976 |
Spot test for vanillylmandelic acid and other guaiacols in urine of patients with neuroblastoma.
Topics: Catechols; Diet; False Positive Reactions; Guaiacol; Humans; Hydrazines; Methods; Neuroblastoma; Per | 1972 |