amphetamine has been researched along with Neuroblastoma in 9 studies
Amphetamine: A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is DEXTROAMPHETAMINE.
1-phenylpropan-2-amine : A primary amine that is isopropylamine in which a hydrogen attached to one of the methyl groups has been replaced by a phenyl group.
amphetamine : A racemate comprising equimolar amounts of (R)-amphetamine (also known as levamphetamine or levoamphetamine) and (S)-amphetamine (also known as dexamfetamine or dextroamphetamine.
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
Excerpt | Relevance | Reference |
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" The aim of the present study was to examine the effects of drugs (amphetamine, methylphenidate and atomoxetine) used in the treatment of attention deficit-hyperactivity disorder on the expression of this enzyme via reverse transcriptase-polymerase chain reaction in human neuroblastoma SH-SY5Y and human monocytic U-937 cells at concentrations of 50, 500 and 5,000 ng/ml." | 3.76 | Impact of psychostimulants and atomoxetine on the expression of 8-hydroxyguanine glycosylase 1 in human cells. ( Clement, HW; Gebhardt, S; Heiser, P; Hemmeter, UM; Kircher, T; Krieg, JC; Schmidt, AJ; Schulz, E, 2010) |
Timeframe | Studies, this research(%) | All Research% |
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pre-1990 | 1 (11.11) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 3 (33.33) | 29.6817 |
2010's | 4 (44.44) | 24.3611 |
2020's | 1 (11.11) | 2.80 |
Authors | Studies |
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Zhou, X | 1 |
Bouitbir, J | 1 |
Liechti, ME | 1 |
Krähenbühl, S | 1 |
Mancuso, RV | 1 |
Xilouri, M | 1 |
Brekk, OR | 1 |
Landeck, N | 1 |
Pitychoutis, PM | 1 |
Papasilekas, T | 1 |
Papadopoulou-Daifoti, Z | 1 |
Kirik, D | 1 |
Stefanis, L | 1 |
Hao, F | 1 |
Yang, C | 1 |
Chen, SS | 1 |
Wang, YY | 1 |
Zhou, W | 1 |
Hao, Q | 1 |
Lu, T | 1 |
Hoffer, B | 1 |
Zhao, LR | 1 |
Duan, WM | 1 |
Xu, QY | 1 |
Schmidt, AJ | 2 |
Krieg, JC | 2 |
Clement, HW | 2 |
Gebhardt, S | 2 |
Schulz, E | 2 |
Heiser, P | 2 |
Hemmeter, UM | 1 |
Kircher, T | 1 |
Mazei-Robison, MS | 1 |
Blakely, RD | 1 |
Kääriäinen, TM | 1 |
Piltonen, M | 1 |
Ossola, B | 1 |
Kekki, H | 1 |
Lehtonen, S | 1 |
Nenonen, T | 1 |
Lecklin, A | 1 |
Raasmaja, A | 1 |
Männistö, PT | 1 |
Klongpanichapak, S | 1 |
Phansuwan-Pujito, P | 1 |
Ebadi, M | 1 |
Govitrapong, P | 1 |
Zwiller, J | 1 |
Treska-Ciesielski, J | 1 |
Mack, G | 1 |
Mandel, P | 1 |
9 other studies available for amphetamine and Neuroblastoma
Article | Year |
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Topics: Adenosine Triphosphate; Amphetamine; Amphetamines; Apoptosis; Cell Differentiation; Cell Line, Tumor | 2020 |
Boosting chaperone-mediated autophagy in vivo mitigates α-synuclein-induced neurodegeneration.
Topics: alpha-Synuclein; Amphetamine; Analysis of Variance; Animals; Apomorphine; Autophagy; Cells, Cultured | 2013 |
Long-term protective effects of AAV9-mesencephalic astrocyte-derived neurotrophic factor gene transfer in parkinsonian rats.
Topics: Adenoviridae; Adrenergic Agents; Amphetamine; Animals; Cells, Cultured; Disease Models, Animal; Dopa | 2017 |
Impact of drugs approved for treating ADHD on the cell survival and energy metabolism: an in-vitro study in human neuronal and immune cells.
Topics: Adenosine Triphosphate; Adrenergic Uptake Inhibitors; Amphetamine; Atomoxetine Hydrochloride; Cell L | 2010 |
Impact of psychostimulants and atomoxetine on the expression of 8-hydroxyguanine glycosylase 1 in human cells.
Topics: Adrenergic Uptake Inhibitors; Amphetamine; Atomoxetine Hydrochloride; Cell Line; Central Nervous Sys | 2010 |
Expression studies of naturally occurring human dopamine transporter variants identifies a novel state of transporter inactivation associated with Val382Ala.
Topics: Alanine; Amphetamine; Animals; Biotinylation; Cattle; Cell Line; Chlorocebus aethiops; Cocaine; COS | 2005 |
Lack of robust protective effect of quercetin in two types of 6-hydroxydopamine-induced parkinsonian models in rats and dopaminergic cell cultures.
Topics: Amphetamine; Animals; Antioxidants; Apomorphine; Behavior, Animal; Cell Line, Tumor; Corpus Striatum | 2008 |
Melatonin inhibits amphetamine-induced increase in alpha-synuclein and decrease in phosphorylated tyrosine hydroxylase in SK-N-SH cells.
Topics: alpha-Synuclein; Amphetamine; Antioxidants; Cell Line, Tumor; Central Nervous System Stimulants; Dos | 2008 |
Uptake of noradrenaline by an adrenergic clone of neuroblastoma cells.
Topics: Amphetamine; Clone Cells; Desipramine; Imipramine; Kinetics; Neuroblastoma; Norepinephrine; Ouabain | 1975 |