Page last updated: 2024-11-02

phloretin and Neuroblastoma

phloretin has been researched along with Neuroblastoma in 12 studies

Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)

Research Excerpts

ExcerptRelevanceReference
"Inositol uptake was studied in the rat CNS neuroblastoma B50 cell line."7.68Inositol metabolism during neuroblastoma B50 cell differentiation: effects of differentiating agents on inositol uptake. ( Reboulleau, CP, 1990)
"Inositol uptake was studied in the rat CNS neuroblastoma B50 cell line."3.68Inositol metabolism during neuroblastoma B50 cell differentiation: effects of differentiating agents on inositol uptake. ( Reboulleau, CP, 1990)
"Phloretin (PLT) is a phenolic compound reported possessing anti-inflammatory and antioxidant activities."1.91Neuroprotective Effect of Phloretin in Rotenone-Induced Mice Model of Parkinson's Disease: Modulating mTOR-NRF2-p62 Mediated Autophagy-Oxidative Stress Crosstalk. ( Khatri, DK; Kumar, R; Preeti, K; Shirgadwar, SM; Singh, SB, 2023)
"Phloretin is a type of dihydrochalcone that is primarily found in apples and has been reported to possess various potent biological activities, such as anticancer, antioxidant and anti-inflammatory effects."1.72Phloretin enhances autophagy by impairing AKT activation and inducing JNK-Beclin-1 pathway activation. ( Fan, C; Teng, J; Tian, Y; Zhang, Y; Zhao, X, 2022)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19905 (41.67)18.7374
1990's4 (33.33)18.2507
2000's1 (8.33)29.6817
2010's0 (0.00)24.3611
2020's2 (16.67)2.80

Authors

AuthorsStudies
Fan, C1
Zhang, Y1
Tian, Y1
Zhao, X1
Teng, J1
Shirgadwar, SM3
Kumar, R3
Preeti, K3
Khatri, DK3
Singh, SB3
Loveday, D1
Heacock, AM1
Fisher, SK1
Pandey, GN1
Davis, JM1
Saneto, RP2
Perez-Polo, JR2
Srivastava, SK1
Werrbach-Perez, K1
Wiese, TJ1
Dunlap, JA1
Yorek, MA1
Bachowska-Mac, M1
Nehlig, A1
Nałecz, MJ1
Nałecz, KA1
Nikolakopoulos, J1
Zachariah, C1
Mota de Freitas, D1
Stubbs, EB1
Ramasamy, R1
Castro, MC1
Geraldes, CF1
Ortmann, R1
Nutto, D1
Waldmeyer, J1
Reboulleau, CP1
Dunlop, ME1
Hill, MA1
Larkins, RG1

Reviews

1 review available for phloretin and Neuroblastoma

ArticleYear
Biology of the lithium ion.
    Advances in experimental medicine and biology, 1980, Volume: 127

    Topics: Animals; Biological Transport; Blood Platelets; Brain Chemistry; Cyclic AMP; Dose-Response Relations

1980

Other Studies

11 other studies available for phloretin and Neuroblastoma

ArticleYear
Phloretin enhances autophagy by impairing AKT activation and inducing JNK-Beclin-1 pathway activation.
    Experimental and molecular pathology, 2022, Volume: 127

    Topics: Apoptosis; Autophagy; Beclin-1; Cell Line, Tumor; Glioblastoma; Humans; Neuroblastoma; Phloretin; Pr

2022
Neuroprotective Effect of Phloretin in Rotenone-Induced Mice Model of Parkinson's Disease: Modulating mTOR-NRF2-p62 Mediated Autophagy-Oxidative Stress Crosstalk.
    Journal of Alzheimer's disease : JAD, 2023, Volume: 94, Issue:s1

    Topics: Animals; Antioxidants; Autophagy; Humans; Kelch-Like ECH-Associated Protein 1; Mice; Mice, Inbred C5

2023
Neuroprotective Effect of Phloretin in Rotenone-Induced Mice Model of Parkinson's Disease: Modulating mTOR-NRF2-p62 Mediated Autophagy-Oxidative Stress Crosstalk.
    Journal of Alzheimer's disease : JAD, 2023, Volume: 94, Issue:s1

    Topics: Animals; Antioxidants; Autophagy; Humans; Kelch-Like ECH-Associated Protein 1; Mice; Mice, Inbred C5

2023
Neuroprotective Effect of Phloretin in Rotenone-Induced Mice Model of Parkinson's Disease: Modulating mTOR-NRF2-p62 Mediated Autophagy-Oxidative Stress Crosstalk.
    Journal of Alzheimer's disease : JAD, 2023, Volume: 94, Issue:s1

    Topics: Animals; Antioxidants; Autophagy; Humans; Kelch-Like ECH-Associated Protein 1; Mice; Mice, Inbred C5

2023
Neuroprotective Effect of Phloretin in Rotenone-Induced Mice Model of Parkinson's Disease: Modulating mTOR-NRF2-p62 Mediated Autophagy-Oxidative Stress Crosstalk.
    Journal of Alzheimer's disease : JAD, 2023, Volume: 94, Issue:s1

    Topics: Animals; Antioxidants; Autophagy; Humans; Kelch-Like ECH-Associated Protein 1; Mice; Mice, Inbred C5

2023
Activation of muscarinic cholinergic receptors enhances the volume-sensitive efflux of myo-inositol from SH-SY5Y neuroblastoma cells.
    Journal of neurochemistry, 2003, Volume: 87, Issue:2

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Calcium; Humans; Inositol; Ion Channels; Muscarini

2003
Differences in the accumulation of lithium in human neuroblastoma and glioma cells in tissue culture.
    Journal of neuroscience research, 1982, Volume: 7, Issue:4

    Topics: Cell Membrane Permeability; Clone Cells; Depression, Chemical; Glioma; Humans; Kinetics; Lithium; Ne

1982
Lithium uptake at physiological ion concentrations in a human clonal neuroblastoma cell line.
    Journal of neurochemistry, 1980, Volume: 34, Issue:6

    Topics: Biological Transport; Cell Line; Clone Cells; Humans; Lithium; Neuroblastoma; Ouabain; Phloretin; Po

1980
L-fucose is accumulated via a specific transport system in eukaryotic cells.
    The Journal of biological chemistry, 1994, Sep-09, Volume: 269, Issue:36

    Topics: Animals; Aorta; Biological Transport; Cattle; Cell Line; Cells, Cultured; Cerebrovascular Circulatio

1994
Transport of alpha-ketoisocaproate in neuroblastoma NB-2a cells.
    Biochemical and biophysical research communications, 1997, Aug-08, Volume: 237, Issue:1

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Aminooxyacetic Acid; Biological Transport; Caproat

1997
7Li nuclear magnetic resonance study for the determination of Li+ properties in neuroblastoma SH-SY5Y cells.
    Journal of neurochemistry, 1998, Volume: 71, Issue:4

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Cell Survival; Humans; Intracellular Fluid; Ion Tr

1998
Phloretin and related compounds inhibit agonist stimulated cAMP accumulation in cultured cells of CNS origin.
    Biochemical pharmacology, 1979, Aug-01, Volume: 28, Issue:15

    Topics: Adenosine; Animals; Astrocytoma; Cells, Cultured; Central Nervous System; Cyclic AMP; Glycosides; Hu

1979
Inositol metabolism during neuroblastoma B50 cell differentiation: effects of differentiating agents on inositol uptake.
    Journal of neurochemistry, 1990, Volume: 55, Issue:2

    Topics: Amiloride; Animals; Biological Transport; Bucladesine; Calcium; Cell Differentiation; Cytochalasin B

1990
The influence of insulin and sorbinil on myoinositol uptake in peripheral nerve from normal and diabetic rats and a neuroblastoma cell line (N1E-115).
    Diabetes research (Edinburgh, Scotland), 1988, Volume: 8, Issue:2

    Topics: Aldehyde Reductase; Animals; Cell Line; Diabetes Mellitus, Experimental; Femoral Nerve; Glucose; Imi

1988