Page last updated: 2024-08-23

quinpirole and Neuroblastoma

quinpirole has been researched along with Neuroblastoma in 13 studies

*Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51) [MeSH]

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's10 (76.92)18.2507
2000's3 (23.08)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bunzow, JR; Civelli, O; Guan, HC; Niznik, HB; Seeman, P; Sunahara, RK; Van Tol, HH1
Fukunaga, K; Takeuchi, Y1
Buck, DC; Macey, TA; Neve, KA; Wang, C; Yang, R1
Albert, PR; Bulman, DE; Daigle, M; Grimes, DA; Jacobsen, KX; Lemonde, S; MacDonald, H1
Brown, NA; Seabrook, GR1
Freedman, SB; Kemp, JA; McAllister, G; Patel, S; Seabrook, GR; Sinclair, HA1
Dimitriadou, V; Griffon, N; Lévesque, D; Martres, MP; Pilon, C; Schwartz, JC; Sokoloff, P1
Farooqui, SM1
Castellano, MA; Chiodo, LA; Kapatos, G; Liu, LX; Monsma, FJ; Sibley, DR1
Costentin, J; Diaz, J; Griffon, N; Lévesque, D; Mann, A; Pilon, C; Sautel, F; Schwartz, JC; Simon, P; Sokoloff, P; Wermuth, CG1
Griffon, N; Pilon, C; Sautel, F; Schwartz, JC; Sokoloff, P1
Conneely, OM; Gangolli, EA; O'Malley, BW1
Cumbay, MG; Neve, KA; Neve, RL; Vu, MN; Watts, VJ; Wiens, BL1

Reviews

1 review(s) available for quinpirole and Neuroblastoma

ArticleYear
Functional models for the dopamine D3 receptor.
    Biochemical Society transactions, 1996, Volume: 24, Issue:1

    Topics: Animals; Cell Division; Cell Line; Cyclic AMP; Dopamine Agonists; Ergolines; Gene Expression; Glioma; Models, Biological; Naphthalenes; Neuroblastoma; Neurotensin; Nucleus Accumbens; Pyrrolidines; Quinpirole; Receptors, Dopamine D2; Receptors, Dopamine D3; Recombinant Proteins; Transfection

1996

Other Studies

12 other study(ies) available for quinpirole and Neuroblastoma

ArticleYear
Cloning of the gene for a human dopamine D4 receptor with high affinity for the antipsychotic clozapine.
    Nature, 1991, Apr-18, Volume: 350, Issue:6319

    Topics: Amino Acid Sequence; Animals; Binding, Competitive; Blotting, Northern; Brain; Cell Line; Cloning, Molecular; Clozapine; Gene Library; Humans; Kinetics; Molecular Sequence Data; Molecular Weight; Neuroblastoma; Organ Specificity; Protein Conformation; Rats; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Dopamine D4; Restriction Mapping; RNA, Messenger; Sequence Homology, Nucleic Acid; Transfection

1991
Dopamine D2 receptor activates extracellular signal-regulated kinase through the specific region in the third cytoplasmic loop.
    Journal of neurochemistry, 2004, Volume: 89, Issue:6

    Topics: Animals; Cell Line; Colforsin; Enzyme Activation; Genes, Reporter; Intracellular Space; Mice; Mitogen-Activated Protein Kinases; Neuroblastoma; NF-kappa B; Protein Structure, Tertiary; Quinpirole; Rats; Receptors, Dopamine D2; Response Elements; Sequence Deletion; Structure-Activity Relationship; Transfection

2004
Dopamine D2 receptor stimulation of mitogen-activated protein kinases mediated by cell type-dependent transactivation of receptor tyrosine kinases.
    Journal of neurochemistry, 2005, Volume: 93, Issue:4

    Topics: Animals; Animals, Newborn; Blotting, Western; Cells, Cultured; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Epidermal Growth Factor; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; Genetic Vectors; Humans; Indole Alkaloids; Microscopy, Confocal; Neuroblastoma; Piperazines; Platelet-Derived Growth Factor; Quinazolines; Quinpirole; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor Protein-Tyrosine Kinases; Receptors, Dopamine D2; Simplexvirus; Spiperone; Transcriptional Activation; Transfection; Tritium; Tyrphostins

2005
A Nurr1 point mutant, implicated in Parkinson's disease, uncouples ERK1/2-dependent regulation of tyrosine hydroxylase transcription.
    Neurobiology of disease, 2008, Volume: 29, Issue:1

    Topics: Cell Line, Transformed; Cysteine; DNA-Binding Proteins; Dopamine Agonists; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation; Humans; Mitogen-Activated Protein Kinase 3; Mutation; Neuroblastoma; Nuclear Receptor Subfamily 4, Group A, Member 2; Quinpirole; Serine; Transcription Factors; Transfection; Tyrosine 3-Monooxygenase

2008
Phosphorylation- and voltage-dependent inhibition of neuronal calcium currents by activation of human D2(short) dopamine receptors.
    British journal of pharmacology, 1995, Volume: 115, Issue:3

    Topics: Calcium; Calcium Channel Blockers; Calcium Channels; Cyclic AMP; Diglycerides; Dopamine Agonists; Electric Stimulation; Electrophysiology; Enzyme Inhibitors; Ergolines; Ethers, Cyclic; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Neuroblastoma; Neurons; Okadaic Acid; omega-Conotoxin GVIA; Patch-Clamp Techniques; Peptides; Pertussis Toxin; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase C; Protein Phosphatase 1; Quinpirole; Receptors, Dopamine D2; Transfection; Tumor Cells, Cultured; Virulence Factors, Bordetella

1995
Functional expression of human D3 dopamine receptors in differentiated neuroblastoma x glioma NG108-15 cells.
    British journal of pharmacology, 1994, Volume: 111, Issue:2

    Topics: Brain Neoplasms; Calcium Channel Blockers; Calcium Channels; Cell Differentiation; Dopamine Agents; Ergolines; Glioma; GTP-Binding Proteins; Humans; Neuroblastoma; Polymerase Chain Reaction; Quinpirole; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Dopamine D3; RNA, Messenger; Sulpiride; Tumor Cells, Cultured

1994
Functional coupling of the human dopamine D3 receptor in a transfected NG 108-15 neuroblastoma-glioma hybrid cell line.
    European journal of pharmacology, 1994, Jul-15, Volume: 268, Issue:2

    Topics: Animals; Cyclic AMP; Ergolines; Genes, fos; Glioma; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Hybrid Cells; Mice; Neuroblastoma; Quinpirole; Rats; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Dopamine D3; Sulpiride; Thymidine; Transfection; Tumor Cells, Cultured

1994
Induction of adenylate cyclase sensitive dopamine D2-receptors in retinoic acid induced differentiated human neuroblastoma SHSY-5Y cells.
    Life sciences, 1994, Volume: 55, Issue:24

    Topics: Adenylyl Cyclases; Amino Acid Sequence; Base Sequence; Benzamides; Cell Differentiation; Cyclic AMP; Dopamine Agonists; Dopamine Antagonists; Ergolines; Humans; Molecular Sequence Data; Neuroblastoma; Neurons; Quinpirole; Receptors, Dopamine D2; RNA, Messenger; Second Messenger Systems; Sulpiride; Tretinoin; Tumor Cells, Cultured

1994
Transfected D2 short dopamine receptors inhibit voltage-dependent potassium current in neuroblastoma x glioma hybrid (NG108-15) cells.
    Molecular pharmacology, 1993, Volume: 44, Issue:3

    Topics: Calcium; Dopamine; Ergolines; Glioma; GTP-Binding Proteins; Hybrid Cells; Membrane Potentials; Neuroblastoma; Neurons; Pertussis Toxin; Potassium Channels; Quinpirole; Receptors, Dopamine D2; Recombinant Proteins; Tumor Cells, Cultured; Virulence Factors, Bordetella

1993
Antipsychotics with inverse agonist activity at the dopamine D3 receptor.
    Journal of neural transmission (Vienna, Austria : 1996), 1996, Volume: 103, Issue:10

    Topics: Animals; Antipsychotic Agents; Calcium; CHO Cells; Clozapine; Colforsin; Cricetinae; Cyclic AMP; DNA Replication; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Flupenthixol; Glioma; Haloperidol; Humans; Hybrid Cells; Naphthalenes; Neuroblastoma; Pertussis Toxin; Phenothiazines; Pimozide; Pyrrolidines; Quinpirole; Receptors, Dopamine D2; Receptors, Dopamine D3; Recombinant Proteins; Risperidone; Salicylamides; Second Messenger Systems; Sulpiride; Tetrahydronaphthalenes; Tumor Cells, Cultured; Virulence Factors, Bordetella

1996
Neurotransmitters activate the human estrogen receptor in a neuroblastoma cell line.
    The Journal of steroid biochemistry and molecular biology, 1997, Volume: 61, Issue:1-2

    Topics: Adenoviridae; Benzazepines; Carbachol; Cyclic AMP-Dependent Protein Kinases; Dopamine; Enzyme Inhibitors; Estradiol; Genetic Vectors; Humans; Isoquinolines; Ligands; Muscarinic Agonists; Neuroblastoma; Neurons; Neurotransmitter Agents; Quinpirole; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Estrogen; Sequence Deletion; Sulfonamides; Transcriptional Activation; Transfection; Tumor Cells, Cultured

1997
Selective activation of Galphao by D2L dopamine receptors in NS20Y neuroblastoma cells.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1998, Nov-01, Volume: 18, Issue:21

    Topics: Adenylate Cyclase Toxin; Animals; Colforsin; Cyclic AMP; Enzyme Activation; Genetic Vectors; GTP-Binding Proteins; Mice; Neuroblastoma; Neurons; Pertussis Toxin; Quinpirole; Receptors, Dopamine D2; Simplexvirus; Transfection; Tumor Cells, Cultured; Virulence Factors, Bordetella

1998