quipazine has been researched along with Neuroblastoma in 7 studies
Quipazine: A pharmacologic congener of serotonin that contracts smooth muscle and has actions similar to those of tricyclic antidepressants. It has been proposed as an oxytocic.
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The pharmacological characteristics of 5-HT3 receptor (5-hydroxytryptamine3 receptor) recognition sites labelled with [3H]-(S)-zacopride and [3H]granisetron in membranes prepared from NG108-15 neuroblastoma-glioma cells were directly compared to investigate further differences in the binding characteristics of these two radioligands." | 7.68 | Differential binding characteristics of agonists at 5-HT3 receptor recognition sites in NG108-15 neuroblastoma-glioma cells labelled by [3H]-(S)-zacopride and [3H]granisetron. ( Barnes, JM; Barnes, NM, 1993) |
| " The biochemical and pharmacological properties of 5-HT3 receptors in homogenates of NG108-15 and NCB-20 neuroblastoma cells and rat cerebral cortex have been ascertained by the use of [3H]-quipazine and [3H]-GR65630 binding." | 7.68 | Characteristics of 5-HT3 binding sites in NG108-15, NCB-20 neuroblastoma cells and rat cerebral cortex using [3H]-quipazine and [3H]-GR65630 binding. ( Eglen, RM; Loury, DN; Michel, AD; Sharif, NA; Stefanich, E; Whiting, RL; Wong, EH, 1991) |
| "The pharmacological characteristics of 5-HT3 receptor (5-hydroxytryptamine3 receptor) recognition sites labelled with [3H]-(S)-zacopride and [3H]granisetron in membranes prepared from NG108-15 neuroblastoma-glioma cells were directly compared to investigate further differences in the binding characteristics of these two radioligands." | 3.68 | Differential binding characteristics of agonists at 5-HT3 receptor recognition sites in NG108-15 neuroblastoma-glioma cells labelled by [3H]-(S)-zacopride and [3H]granisetron. ( Barnes, JM; Barnes, NM, 1993) |
| " The biochemical and pharmacological properties of 5-HT3 receptors in homogenates of NG108-15 and NCB-20 neuroblastoma cells and rat cerebral cortex have been ascertained by the use of [3H]-quipazine and [3H]-GR65630 binding." | 3.68 | Characteristics of 5-HT3 binding sites in NG108-15, NCB-20 neuroblastoma cells and rat cerebral cortex using [3H]-quipazine and [3H]-GR65630 binding. ( Eglen, RM; Loury, DN; Michel, AD; Sharif, NA; Stefanich, E; Whiting, RL; Wong, EH, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rosen, T | 1 |
| Seeger, TF | 1 |
| McLean, S | 1 |
| Nagel, AA | 1 |
| Ives, JL | 1 |
| Guarino, KJ | 1 |
| Bryce, D | 1 |
| Furman, J | 1 |
| Roth, RW | 1 |
| Chalabi, PM | 1 |
| Cappelli, A | 1 |
| Anzini, M | 1 |
| Vomero, S | 1 |
| Mennuni, L | 1 |
| Makovec, F | 1 |
| Doucet, E | 1 |
| Hamon, M | 1 |
| Bruni, G | 1 |
| Romeo, MR | 1 |
| Menziani, MC | 1 |
| De Benedetti, PG | 1 |
| Langer, T | 1 |
| Wong, EH | 2 |
| Bonhaus, DW | 1 |
| Lee, JA | 1 |
| Wu, I | 1 |
| Loury, DN | 2 |
| Eglen, RM | 2 |
| Morain, P | 1 |
| Abraham, C | 1 |
| Lacoste, JM | 1 |
| Malen, C | 1 |
| Laubie, M | 1 |
| Giesen-Crouse, E | 1 |
| Barnes, JM | 1 |
| Barnes, NM | 1 |
| Newton, RA | 1 |
| Phipps, SL | 1 |
| Flanigan, TP | 1 |
| Newberry, NR | 1 |
| Carey, JE | 1 |
| Kumar, C | 1 |
| McDonald, B | 1 |
| Chen, C | 1 |
| Elliott, JM | 1 |
| Sharif, NA | 1 |
| Stefanich, E | 1 |
| Michel, AD | 1 |
| Whiting, RL | 1 |
7 other studies available for quipazine and Neuroblastoma
| Article | Year |
|---|---|
Synthesis, in vitro binding profile, and central nervous system penetrability of the highly potent 5-HT3 receptor antagonist [3H]-4-(2-methoxyphenyl)-2-[4(5)-methyl-5(4)-imidazolylmethyl]thiazole.
Topics: Animals; Blood-Brain Barrier; Brain; Chemical Phenomena; Chemistry; Glioma; Imidazoles; Mice; Molecu | 1990 |
Novel potent and selective central 5-HT3 receptor ligands provided with different intrinsic efficacy. 1. Mapping the central 5-HT3 receptor binding site by arylpiperazine derivatives.
Topics: Animals; Benzene; Binding Sites; Glioma; Guanidine; Mice; Models, Molecular; Molecular Structure; Ne | 1998 |
Different densities of 5-HT3 receptors are labeled by [3H]quipazine, [3H]GR 65630 and [3H]granisetron.
Topics: Animals; Binding, Competitive; Cerebral Cortex; Cricetinae; Granisetron; Guinea Pigs; Ileum; Imidazo | 1993 |
The antagonist properties of S 11978 on 5HT3 receptors in N1E-115 neuroblastoma cells.
Topics: Animals; Binding, Competitive; Electrophysiology; Indoles; Kinetics; Mice; Neuroblastoma; Ondansetro | 1993 |
Differential binding characteristics of agonists at 5-HT3 receptor recognition sites in NG108-15 neuroblastoma-glioma cells labelled by [3H]-(S)-zacopride and [3H]granisetron.
Topics: Animals; Benzamides; Biguanides; Binding Sites; Binding, Competitive; Bridged Bicyclo Compounds; Bri | 1993 |
Characterisation of human 5-hydroxytryptamine2A and 5-hydroxytryptamine2C receptors expressed in the human neuroblastoma cell line SH-SY5Y: comparative stimulation by hallucinogenic drugs.
Topics: Adrenergic alpha-Agonists; Amphetamines; Antiparkinson Agents; Calcium; Choroid Plexus; Electrophysi | 1996 |
Characteristics of 5-HT3 binding sites in NG108-15, NCB-20 neuroblastoma cells and rat cerebral cortex using [3H]-quipazine and [3H]-GR65630 binding.
Topics: Animals; Binding, Competitive; Cell Line; Cerebral Cortex; Imidazoles; Indoles; Kinetics; Ligands; M | 1991 |