Page last updated: 2024-11-03

procaine and Neuroblastoma

procaine has been researched along with Neuroblastoma in 3 studies

Procaine: A local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1016).
procaine : A benzoate ester, formally the result of esterification of 4-aminobenzoic acid with 2-diethylaminoethanol but formed experimentally by reaction of ethyl 4-aminobenzoate with 2-diethylaminoethanol.

Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)

Research Excerpts

ExcerptRelevanceReference
" Shorter exposure times (3 hr) resulted in a marginal toxic effect (32%)."5.27Toxicity of chloroprocaine and sodium bisulfite on human neuroblastoma cells. ( Lear, E; Seravalli, E, 1987)
" Shorter exposure times (3 hr) resulted in a marginal toxic effect (32%)."1.27Toxicity of chloroprocaine and sodium bisulfite on human neuroblastoma cells. ( Lear, E; Seravalli, E, 1987)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's2 (66.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hilton, AB1
Lockhart, EM1
Penning, DH1
Huang, FS1
Hu, Q1
Shi, YL1
Seravalli, E1
Lear, E1

Other Studies

3 other studies available for procaine and Neuroblastoma

ArticleYear
Epidural analgesia in parturients with previous spinal irradiation.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1998, Volume: 45, Issue:9

    Topics: Adolescent; Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Anesthetics, Loc

1998
[The inhibitory effects of artemisinin-derivatives on Na+ and K+ channels in comparison with those of procaine].
    Sheng li xue bao : [Acta physiologica Sinica], 1998, Volume: 50, Issue:2

    Topics: Anesthetics, Local; Animals; Artemisinins; Drugs, Chinese Herbal; Glioma; Hybrid Cells; Mice; Neurob

1998
Toxicity of chloroprocaine and sodium bisulfite on human neuroblastoma cells.
    Anesthesia and analgesia, 1987, Volume: 66, Issue:10

    Topics: Cell Division; Cell Line; Colony-Forming Units Assay; Humans; In Vitro Techniques; Neuroblastoma; Pr

1987