procaine has been researched along with Neuroblastoma in 3 studies
Procaine: A local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1016).
procaine : A benzoate ester, formally the result of esterification of 4-aminobenzoic acid with 2-diethylaminoethanol but formed experimentally by reaction of ethyl 4-aminobenzoate with 2-diethylaminoethanol.
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
Excerpt | Relevance | Reference |
---|---|---|
" Shorter exposure times (3 hr) resulted in a marginal toxic effect (32%)." | 5.27 | Toxicity of chloroprocaine and sodium bisulfite on human neuroblastoma cells. ( Lear, E; Seravalli, E, 1987) |
" Shorter exposure times (3 hr) resulted in a marginal toxic effect (32%)." | 1.27 | Toxicity of chloroprocaine and sodium bisulfite on human neuroblastoma cells. ( Lear, E; Seravalli, E, 1987) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (33.33) | 18.7374 |
1990's | 2 (66.67) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Hilton, AB | 1 |
Lockhart, EM | 1 |
Penning, DH | 1 |
Huang, FS | 1 |
Hu, Q | 1 |
Shi, YL | 1 |
Seravalli, E | 1 |
Lear, E | 1 |
3 other studies available for procaine and Neuroblastoma
Article | Year |
---|---|
Epidural analgesia in parturients with previous spinal irradiation.
Topics: Adolescent; Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Anesthetics, Loc | 1998 |
[The inhibitory effects of artemisinin-derivatives on Na+ and K+ channels in comparison with those of procaine].
Topics: Anesthetics, Local; Animals; Artemisinins; Drugs, Chinese Herbal; Glioma; Hybrid Cells; Mice; Neurob | 1998 |
Toxicity of chloroprocaine and sodium bisulfite on human neuroblastoma cells.
Topics: Cell Division; Cell Line; Colony-Forming Units Assay; Humans; In Vitro Techniques; Neuroblastoma; Pr | 1987 |