Page last updated: 2024-10-15

2-oxo-3-methylvalerate and Neuroblastoma

2-oxo-3-methylvalerate has been researched along with Neuroblastoma in 1 studies

alpha-keto-beta-methylvaleric acid: RN given refers to parent cpd
3-methyl-2-oxovaleric acid : A 2-oxo monocarboxylic acid that is valeric acid carrying oxo- and methyl substituents at C-2 and C-3, respectively. An alpha-keto acid analogue and metabolite of isoleucine in man, animals and bacteria. Used as a clinical marker for maple syrup urine disease (MSUD).

Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Huang, HM1
Zhang, H1
Xu, H1
Gibson, GE1

Other Studies

1 other study available for 2-oxo-3-methylvalerate and Neuroblastoma

ArticleYear
Inhibition of the alpha-ketoglutarate dehydrogenase complex alters mitochondrial function and cellular calcium regulation.
    Biochimica et biophysica acta, 2003, Jan-20, Volume: 1637, Issue:1

    Topics: Calcium; Cations, Divalent; Cytochrome c Group; Enzyme Inhibitors; Fluorescent Dyes; Fura-2; Humans;

2003