spermidine has been researched along with Neuroblastoma in 10 studies
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
| Excerpt | Relevance | Reference |
|---|---|---|
| "When incubated with cultured mouse neuroblastoma cells under growth stimulatory condition, [3H]putrescine or [3H]spermidine can metabolically label a cellular protein of apparent molecular mass 18 kDa." | 7.67 | NAD+ stimulated the spermidine-dependent hypusine formation on the 18 kDa protein in cytosolic lysates derived from NB-15 mouse neuroblastoma cells. ( Chen, KY; Dou, QP, 1988) |
| "The biochemical properties of polyamine transport system have been studied in detail in NB-15 mouse neuroblastoma cells in culture by measuring the uptake of [14C]putrescine under various experimentally imposed pharmacological conditions." | 3.67 | Characterization of the polyamine transport system in mouse neuroblastoma cells. Effects of sodium and system A amino acids. ( Chen, KY; Rinehart, CA, 1984) |
| "When incubated with cultured mouse neuroblastoma cells under growth stimulatory condition, [3H]putrescine or [3H]spermidine can metabolically label a cellular protein of apparent molecular mass 18 kDa." | 3.67 | NAD+ stimulated the spermidine-dependent hypusine formation on the 18 kDa protein in cytosolic lysates derived from NB-15 mouse neuroblastoma cells. ( Chen, KY; Dou, QP, 1988) |
| "Abnormal tau build-up is a hallmark of Alzheimer's disease (AD) and more than 20 other serious neurodegenerative diseases." | 1.91 | Spermidine Rescues Bioenergetic and Mitophagy Deficits Induced by Disease-Associated Tau Protein. ( Eckert, A; Fairley, LH; Grimm, A; Lejri, I, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (50.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Herp, D | 1 |
| Ridinger, J | 1 |
| Robaa, D | 1 |
| Shinsky, SA | 1 |
| Schmidtkunz, K | 1 |
| Yesiloglu, TZ | 1 |
| Bayer, T | 1 |
| Steimbach, RR | 1 |
| Herbst-Gervasoni, CJ | 1 |
| Merz, A | 1 |
| Romier, C | 1 |
| Sehr, P | 1 |
| Gunkel, N | 1 |
| Miller, AK | 1 |
| Christianson, DW | 1 |
| Oehme, I | 1 |
| Sippl, W | 1 |
| Jung, M | 1 |
| Fairley, LH | 1 |
| Lejri, I | 1 |
| Grimm, A | 1 |
| Eckert, A | 1 |
| Musa, H | 1 |
| Veenstra, RD | 1 |
| Dot, J | 1 |
| Lluch, M | 1 |
| Blanco, I | 1 |
| RodrÃguez-Alvarez, J | 1 |
| Chen, KY | 3 |
| Presepe, V | 1 |
| Parken, N | 1 |
| Liu, AY | 1 |
| Mach, M | 1 |
| Schneider, U | 1 |
| Kersten, W | 1 |
| Rinehart, CA | 1 |
| Fujiwara, K | 1 |
| Araki, M | 1 |
| Kitagawa, T | 1 |
| Inoue, Y | 1 |
| Kremzner, LT | 1 |
| Hiller, JM | 1 |
| Simon, EJ | 1 |
| Dou, QP | 1 |
10 other studies available for spermidine and Neuroblastoma
| Article | Year |
|---|---|
First Fluorescent Acetylspermidine Deacetylation Assay for HDAC10 Identifies Selective Inhibitors with Cellular Target Engagement.
Topics: Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Neuroblastoma; Polyamines; Spermidine; | 2022 |
Spermidine Rescues Bioenergetic and Mitophagy Deficits Induced by Disease-Associated Tau Protein.
Topics: Adenosine Triphosphate; Alzheimer Disease; Energy Metabolism; Humans; Mitophagy; Neuroblastoma; Sper | 2023 |
Voltage-dependent blockade of connexin40 gap junctions by spermine.
Topics: Animals; Connexin 43; Connexins; Dose-Response Relationship, Drug; Electric Conductivity; Gap Juncti | 2003 |
Polyamine uptake in cultured cerebellar granule neurons.
Topics: Animals; Astrocytes; Biogenic Polyamines; Brain Neoplasms; Cell Line, Tumor; Cells, Cultured; Cerebe | 2004 |
Changes of ornithine decarboxylase activity and polyamine content upon differentiation of mouse NB-15 neuroblastoma cells.
Topics: Acetylcholinesterase; Animals; Carboxy-Lyases; Cell Differentiation; Cell Line; Cyclic AMP; Mice; Ne | 1982 |
Excretion of polyamines by children with leukemia during chemotherapy.
Topics: Child; Child, Preschool; Female; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Methyla | 1983 |
Characterization of the polyamine transport system in mouse neuroblastoma cells. Effects of sodium and system A amino acids.
Topics: Amino Acids; Animals; Biological Transport; Cell Line; Ionophores; Kinetics; Mice; Neuroblastoma; Po | 1984 |
A new enzyme-linked immunosorbent assay (ELISA) for studying immunocytochemical procedures using an antiserum produced against spermidine as a model.
Topics: Enzyme-Linked Immunosorbent Assay; Humans; Immune Sera; Melanoma; Models, Biological; Neuroblastoma; | 1993 |
Metabolism of polyamines in mouse neuroblastoma cells in culture: formation of GABA and putreanine.
Topics: Aminobutyrates; Cell Line; gamma-Aminobutyric Acid; Neuroblastoma; Ornithine; Polyamines; Putrescine | 1975 |
NAD+ stimulated the spermidine-dependent hypusine formation on the 18 kDa protein in cytosolic lysates derived from NB-15 mouse neuroblastoma cells.
Topics: Animals; Cell Line; Cytosol; Lysine; Mice; Molecular Weight; NAD; Nerve Tissue Proteins; Neuroblasto | 1988 |