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acetaldehyde and Neuroblastoma

acetaldehyde has been researched along with Neuroblastoma in 6 studies

Acetaldehyde: A colorless, flammable liquid used in the manufacture of acetic acid, perfumes, and flavors. It is also an intermediate in the metabolism of alcohol. It has a general narcotic action and also causes irritation of mucous membranes. Large doses may cause death from respiratory paralysis.
acetaldehyde : The aldehyde formed from acetic acid by reduction of the carboxy group. It is the most abundant carcinogen in tobacco smoke.
aldehyde : A compound RC(=O)H, in which a carbonyl group is bonded to one hydrogen atom and to one R group.
acetyl group : A group, formally derived from acetic acid by dehydroxylation, which is fundamental to the biochemistry of all forms of life. When bound to coenzyme A, it is central to the metabolism of carbohydrates and fats.

Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)

Research Excerpts

ExcerptRelevanceReference
" We recently reported that ethanol and acetaldehyde, the first product of ethanol metabolism, affect transcription of opioid system genes in human SH-SY5Y neuroblastoma cells."7.77Ethanol and acetaldehyde exposure induces specific epigenetic modifications in the prodynorphin gene promoter in a human neuroblastoma cell line. ( Candeletti, S; D'Addario, C; Ekström, TJ; Johansson, S; Ögren, SO; Romualdi, P; Terenius, L, 2011)
" We recently reported that ethanol and acetaldehyde, the first product of ethanol metabolism, affect transcription of opioid system genes in human SH-SY5Y neuroblastoma cells."3.77Ethanol and acetaldehyde exposure induces specific epigenetic modifications in the prodynorphin gene promoter in a human neuroblastoma cell line. ( Candeletti, S; D'Addario, C; Ekström, TJ; Johansson, S; Ögren, SO; Romualdi, P; Terenius, L, 2011)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's0 (0.00)18.2507
2000's4 (66.67)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
D'Addario, C2
Johansson, S1
Candeletti, S1
Romualdi, P1
Ögren, SO2
Terenius, L2
Ekström, TJ1
Jung, TW2
Lee, JY2
Shim, WS2
Kang, ES2
Kim, SK1
Ahn, CW2
Lee, HC2
Cha, BS2
Kim, JS1
Nie, CL1
Wei, Y1
Chen, X1
Liu, YY1
Dui, W1
Liu, Y1
Davies, MC1
Tendler, SJ1
He, RG1
Ming, Y1
Rama, BN1
Prasad, KN1

Other Studies

6 other studies available for acetaldehyde and Neuroblastoma

ArticleYear
Ethanol and acetaldehyde exposure induces specific epigenetic modifications in the prodynorphin gene promoter in a human neuroblastoma cell line.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2011, Volume: 25, Issue:3

    Topics: Acetaldehyde; Cell Line, Tumor; Central Nervous System Depressants; Chromatin; DNA Methylation; Enke

2011
Rosiglitazone protects human neuroblastoma SH-SY5Y cells against acetaldehyde-induced cytotoxicity.
    Biochemical and biophysical research communications, 2006, Feb-03, Volume: 340, Issue:1

    Topics: Acetaldehyde; Apoptosis; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Drug Com

2006
Adiponectin protects human neuroblastoma SH-SY5Y cells against acetaldehyde-induced cytotoxicity.
    Biochemical pharmacology, 2006, Aug-28, Volume: 72, Issue:5

    Topics: Acetaldehyde; Adiponectin; Apoptosis; Caspase 3; Caspases; Cell Line, Tumor; Cytochromes c; Humans;

2006
Formaldehyde at low concentration induces protein tau into globular amyloid-like aggregates in vitro and in vivo.
    PloS one, 2007, Jul-18, Volume: 2, Issue:7

    Topics: Acetaldehyde; Amyloid; Animals; Cell Line, Tumor; Dose-Response Relationship, Drug; Formaldehyde; Hi

2007
The role of acetaldehyde in mediating effects of alcohol on expression of endogenous opioid system genes in a neuroblastoma cell line.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2008, Volume: 22, Issue:3

    Topics: Acetaldehyde; Cell Line, Tumor; Cell Survival; Ethanol; Fomepizole; Gene Expression Regulation; Huma

2008
Ethanol. A heat sensitizer on neuroblastoma cells in culture.
    Cancer, 1986, Mar-15, Volume: 57, Issue:6

    Topics: Acetaldehyde; Acetates; Acetic Acid; Animals; Cell Division; Cell Line; Cell Survival; Ethanol; Hot

1986