tetradecanoylphorbol acetate has been researched along with Neuroblastoma in 244 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 47 (19.26) | 18.7374 |
1990's | 138 (56.56) | 18.2507 |
2000's | 48 (19.67) | 29.6817 |
2010's | 11 (4.51) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Dey, CS; Mishra, D | 1 |
Looyenga, BD; MacKeigan, JP; Resau, J | 1 |
Farrelly, LA; O'Callaghan, C; Savage, NT; Toulouse, A; Yilmazer-Hanke, DM | 1 |
Bamidele, AO; Clift, IC; Hedin, KE; Kremer, KN; Rodriguez-Ramirez, C | 1 |
Harhaji-Trajkovic, L; Janjetovic, K; Misirkic-Marjanovic, M; Tovilovic-Kovacevic, G; Trajkovic, V; Vucicevic, L; Zogovic, N | 1 |
Guevara-Lora, I; Kozik, A; Niewiarowska-Sendo, A; Patrzalek, K | 1 |
Beltramini, M; Bisaglia, M; Bubacco, L; Civiero, L; Codolo, G; Ferrari, V; Filograna, R; Greggio, E | 1 |
Alfredsson, CF; Liang, QL; Nånberg, E; Rendel, F; Sundström, BE | 1 |
Bosier, B; Hermans, E; Lambert, DM | 1 |
Harris, B; Parkin, E | 1 |
Chang, PA; Liu, CY; Wu, YJ | 1 |
Ben, LH; Cravens, PD; Gocke, AR; Hussain, RZ; Liu, Y; Lovett-Racke, AE; McTigue, DM; Peng, H; Puttaparthi, K; Racke, MK; Wei, P; Winger, R; Yang, Y | 1 |
Baba, M; Kato, K; Kodama, T; Kudo, T; Maruyama, D; Morihara, T; Okochi, M; Sadik, G; Tagami, S; Takeda, M; Tanaka, T; Yanagida, K | 1 |
Li, X; Liu, H; Mei, Y; Wang, Z; Ye, J; You, H; Zhang, L; Zhang, Y | 1 |
Christensen, JL; Mandyam, CD; Standifer, KM; Thakker, DR | 1 |
Narita, T; Ohta, S; Taga, T; Takeuchi, Y; Yoshida, S | 1 |
Nałecz, KA; Nałecz, MJ; Sobiesiak-Mirska, J | 1 |
Govoni, S; Mazzucchelli, M; Pascale, A; Racchi, M; Sironi, M | 1 |
Higashino, K; Narita, T; Ohta, S; Taga, T; Takeuchi, Y | 1 |
Choi, BH; Kim, KT; Lee, H; Lee, SK; Suh, BC | 1 |
Hoehner, JC; Prabhakaran, K | 1 |
Chan, DK; Mak, NK; Wagner, GF; Wong, CK; Yeung, HY | 1 |
Nukina, N; Zemskov, EA | 1 |
Amiel, M; Beeri, R; Ehrengruber, MU; Gabai, E; Gal, M; Levy-Lahad, E; Renbaum, P | 1 |
Larsson, C; Raghunath, A; Trollér, U | 1 |
Basta-Kaim, A; Budziszewska, B; Jaworska-Feil, L; Kubera, M; Lasoń, W; Leśkiewicz, M; Tetich, M | 1 |
Culp, LA; Edsjö, A; Karlsson, J; Nilsson, H; Påhlman, S; Pattyn, F; Speleman, F; Vandesompele, J | 1 |
Cowburn, RF; Flood, F; Johnston, JA; Samuelsson, EB; Seiger, A; Sundström, E; Wiehager, B | 1 |
Bate, C; Langeveld, J; Williams, A | 1 |
Dziedzicka-Wasylewska, M; Solich, J | 1 |
Gasch, A; Sattler, M; Schleifenbaum, A; Schultz, C; Stier, G | 1 |
Borwege, S; Joyce, JN; Millan, MJ; Presgraves, SP | 1 |
Bakin, AV; Cowell, JK; Li, X; Ranalli, TA; Sossey-Alaoui, K | 1 |
Chao, MV; Domeniconi, M; Filbin, MT; Hilaire, M; Mellado, W; Spencer, T; Zampieri, N | 1 |
Abramovici, H; Daher, E; Gee, SH; Maillet, JC; Obagi, C; Parks, RJ; Topham, MK; Yakubchyk, Y | 1 |
Endres, K; Fahrenholz, F; Mueller, U; Postina, R; Schroeder, A | 1 |
Karouzaki, S; Mangoura, D; Theofilopoulos, S; Tsirimonaki, E | 1 |
Fisk, L; Nalivaeva, NN; Turner, AJ | 1 |
Arun, P; Madhavarao, CN; Moffett, JR; Namboodiri, MA | 1 |
Fan, Y; Li, HL; Li, ZW; Teng, ZY; Wu, XW; Zhang, YN; Zhang, YQ | 1 |
Czirr, E; Esselmann, H; Leuchtenberger, S; Lichtenthaler, SF; Maler, J; Ness, J; Pietrzik, CU; Weggen, S; Wiltfang, J | 1 |
Abrahamsson, L; Nilsson, K; Odelstad, L; Påhlman, S; Ruusala, AI | 1 |
Abrahamsson, L; Esscher, T; Mattsson, ME; Påhlman, S; Ruusala, AI | 1 |
Mattsson, ME; Påhlman, S; Ruusala, AI | 1 |
Grotte, G; Påhlman, S | 1 |
Ishii, DN; Sonnenfeld, KH; Spinelli, W | 1 |
Grotte, G; Larsson, E; Nilsson, K; Odelstad, L; Påhlman, S | 1 |
Halvorsen, SW; Jiang, N; Malek, R | 1 |
Lavenius, E; Nånberg, E; Påhlman, S; Parrow, V | 1 |
Malbon, CC; Strassheim, D | 1 |
Annunziato, L; Bassi, A; Caso, N; Di Renzo, G; Fatatis, A; Iannotti, E; Mita, GD | 1 |
Chik, CL; Ho, AK; Inukai, T | 1 |
Fisher, J; Han, JH; Kasckow, JW; Mulchahey, JJ; Nemeroff, CB; Owens, MJ; Parkes, DG; Risby, ED | 1 |
Bandoh, S; Maruyama, K; Ohkura, N; Sasaki, K; Tsukada, T; Yamaguchi, K | 1 |
Fagerström, S; Gestblom, C; Hedborg, F; Hoehner, JC; Johansson, I; Larsson, U; Lavenius, E; Nånberg, E; Ortoft, E; Påhlman, S | 1 |
Chambaut-Guérin, AM; Gauthereau, X; Hamimi, C; Martinez, MC; Nunez, J | 1 |
Dreyfus, H; Freysz, L; Lang, D; Leray, C; Massarelli, R; Mestre, R | 1 |
Cox, AJ; Lee, RK; Nitsch, RM; Wurtman, RJ | 1 |
Rebhan, M; Rösner, H; Vacun, G | 1 |
Adem, A; Cazaubon, S; Couraud, PO; Koman, A; Strosberg, AD | 1 |
Ball, SG; Kaye, DF; Peers, C; Reeve, HL; Vaughan, PF | 1 |
Bombien, E; Offermanns, S; Schultz, G | 1 |
Purkiss, JR | 1 |
Krajcik, R; Lerchen, RA; Minth-Worby, CA; Yum, DY | 1 |
Zhang, L | 1 |
Cubells, JF; Joh, TH; Kim, KS; Song, B; Tinti, C | 1 |
Baumgold, J; Curran, P; Fishman, PH; Zhou, XM | 1 |
Byers, DM; Cook, HW; Palmer, FB; Ridgway, ND; Rosé, SD | 1 |
Beckmann, R; Buchner, K; Haller, H; Hucho, F; Lindschau, C | 1 |
Jalava, A; Mai, S | 1 |
Beermann, ML; Griffin, WR; Leli, U; Shea, TB | 1 |
Beyer, EC; Engelmann, GL; Laing, JG; Westphale, EM | 1 |
Thompson, SH; Wang, SS | 1 |
Audette, M; Bouillon, M | 1 |
Chang, SL; Ge, LJ; Kastin, AJ; Zadina, JE | 1 |
Andersson, G; Hammerling, U; Johansson, I; Påhlman, S; Parrow, V | 1 |
Ball, SG; Kaye, DF; McDonald, R; Peers, C; Reeve, HL; Vaughan, PF | 1 |
Fujimoto, M; Shigeri, Y | 1 |
Debré, P; Körner, M; Lee, LM; Pleskoff, O; Tarantino, N | 1 |
Turner, NA; Vaughan, PF; Walker, JH | 1 |
Huang, XY; Morielli, AD; Peralta, EG | 1 |
Maggi, R; Martini, L; Melcangi, RC | 1 |
Hara, A; Taketomi, T; Uemura, K | 1 |
Eriksson, K; Heikkilä, J; Jalava, A | 1 |
Bonavita, V; Kanfer, JN; Massarelli, R; Singh, IN; Sorrentino, G | 1 |
Larsson, C; Simonsson, P | 1 |
Han, JS; Ren, MF; Shun, XJ; Wang, JF; Yang, HF | 1 |
Fukuchi, K; Gomi, K; Takagi, Y; Tomoyasu, S; Tsuruoka, N; Watanabe, H; Watanabe, K | 1 |
Biedler, JL; Cazals-Hatem, D; Hanada, M; Krajewski, S; Reed, JC; Ross, RA; Spengler, BA; Tanaka, S | 1 |
Alling, C; Gustavsson, L; Lundqvist, C; Rodriguez, FD; Simonsson, P | 1 |
Byers, DM; Cook, HW; Palmer, FB; Spence, MW | 2 |
Heikkilä, J; Jalava, A; Lintunen, M | 1 |
Akerman, K; Heikkilä, J; Jalava, A | 1 |
Chen, HC; Huang, FL; Li, H | 1 |
Dussault, JH; Etongue-Mayer, P; Puymirat, J | 1 |
Ball, SG; Balmforth, AJ; McDonald, RL; Palmer, AC; Peers, C; Vaughan, PF | 1 |
Byers, DM; Cook, HW; Morash, SC; Ridgway, DN; Rose, SD | 1 |
Galli, CL; Marinovich, M; Viviani, B | 1 |
Boyd, H; Chik, CL; Ho, AK; Inukai, T; Karpinski, E; Li, B; Ogiwara, T | 1 |
Ahmed, S; Best, A; Kozma, R; Lim, L | 1 |
Fagerström, S; Gestblom, C; Nånberg, E; Påhlman, S | 1 |
Halvorsen, SW; Jiang, N; Malek, R; Wang, X | 1 |
Byers, DM; Cook, HW; Morash, SC; Sproull, SA | 1 |
Jope, RS; Li, X; Song, L | 1 |
Cabedo, H; Felipo, V; Grisolía, S; Miñana, MD | 1 |
Goodall, AR; Vaughan, PF; Walker, JH | 1 |
Di Giulio, AM; Ferro, L; Gorio, A; Lesma, E; Prino, G | 1 |
Ball, SG; Goodall, AR; Turner, NA; Vaughan, PF; Walker, JH | 1 |
Halvorsen, SW; Malek, RL | 2 |
Cianfarani, S; Germani, D; Mercanti, D; Rossi, P; Spagnoli, A | 1 |
Classen, S; Eissner, G; Fichter, M; Hinrichs, R; Scheffer, B; Ueffing, M | 1 |
Lehto, VP; Linnala, A; Virtanen, I | 1 |
Cappabianca, L; Farina, AR; Frati, L; Gulino, A; Mackay, AR; Martinotti, S; Tacconelli, A; Tessitore, A; Tiberio, A | 1 |
Oreland, L; Prince, JA | 1 |
Kuijpers, HJ; Ramaekers, FC; Reutelingsperger, CP; Schutte, B; van Engeland, M | 1 |
Chen, CC; Chen, WC | 1 |
Bönisch, H; Brüss, M; Hammermann, R | 1 |
Gelb, CR; Gies, EK; Knag, KM; Peterfreund, RA; Peters, DM | 1 |
Fink, JS; Gies, EK; Peterfreund, RA | 1 |
Ikegaki, N; Ono, Y; Saito, N; Sakai, N; Sasaki, K; Shirai, Y | 1 |
Chae, HD; Kim, JS; Kim, KT; Nam, JS | 1 |
Kamoshima, W; Kitamura, Y; Nomura, Y; Shimohama, S; Taniguchi, T | 1 |
Bale, TL; Dorsa, DM | 1 |
Fan, GH; Jing, Q; Lou, LG; Ma, L; Pei, G; Wu, YL; Zhang, Z; Zhao, J | 1 |
Kuroda, Y; Kurohara, K; Satoh, J; Yukitake, M | 1 |
Byers, DM; Cook, HW; Morash, SC; Ridgway, ND; Rosé, SD | 1 |
Burgher, KL; Chao, CC; Petko, W; Ringheim, GE; Szczepanik, AM; Zhu, SZ | 1 |
Danks, K; Vaughan, PF; Walker, JH | 1 |
Hiwasa, T; Kondo, K; Nakagawara, A; Nakamura, Y; Ozaki, T; Saido, T; Sakiyama, S | 1 |
Ball, SG; Batten, TF; Danks, K; Vaughan, PF; Wade, JA; Walker, JH | 1 |
Johnson, JA; Moehlenkamp, JD | 1 |
Jope, RS; Zhang, L | 1 |
Axelson, H; Johansson, I; Larsson, C; Ljungberg, J; Ortoft, E; Påhlman, S; Söderholm, H | 1 |
Gnegy, ME; Goldsmith, AM | 1 |
Fagerström, S; Larsson, C; Påhlman, S; Pettersson, L; Sailaja, PR; Truedsson, E; Zeidman, R | 1 |
Aranda, A; Perez-Juste, G | 1 |
Feng, Z; Porter, AG | 1 |
Jope, RS; Pacheco, MA | 1 |
Fisher, SK; Linseman, DA; Sorensen, SD | 1 |
Chambaut-Guérin, AM; Hérigault, S; Lafuma, C; Rouet-Benzineb, P; Rouher, C | 1 |
Fort, A; Hertzberg, EL; Hopperstad, M; Kojima, T; Mochizuki, Y; Spray, DC; Srinivas, M; Urban, M | 1 |
Nånberg, E; Olsson, AK; Vadhammar, K | 1 |
Agmon-Levin, N; Altevogt, P; Gutwein, P; Krauss, K; Mechtersheimer, S; Oleszewski, M | 1 |
Baker, S; Bannerman, P; Damodar Reddy, C; Lee, CM; Patti, R; Phillips, PC; Raghunath, M; Sutton, LN | 1 |
Beretta, E; Magni, P; Motta, M; Scaccianoce, E | 1 |
Kuroda, Y; Satoh, J | 1 |
Antony, P; Freysz, L; Kanfer, JN | 1 |
Babajko, S; Chambery, D; De Galle, B; Ehrenborg, E | 1 |
Billardon, C; Carvajal-Gonzalez, S; Gompel, A; Kandouz, M; Lombet, A; Rostène, W; Zujovic, V | 1 |
Lavenius, E; Nånberg, E; Olsson, A; Rönnstrand, L; Söderholm, H | 1 |
Nånberg, E; Olsson, AK | 1 |
Goppelt-Struebe, M; Lanz, S; Ramer, R; Schaefer, D; Schneider, N | 1 |
Jope, RS; Song, L; Zmijewski, JW | 1 |
Cho, S; Gal, J; Joh, TH; Kim, Y; Liu, N; Park, EM; Volpe, BT | 1 |
Kelly, K; Leone, A; Mitsiades, N; Poulaki, V; Spinelli, B; Tsokos, M; Ward, Y | 1 |
Mattingly, RR; Milstein, ML; Mirkin, BL | 1 |
Cetinkaya, C; Guzhova, I; Hultquist, A; Larsson, LG; Nilsson, K; Påhlman, S | 1 |
Larsson, C; Svensson, K; Trollér, U; Zeidman, R | 1 |
Fibach, E; Ishii, DN; Weinstein, IB; Yamasaki, H | 1 |
Gotoh, K; Kimura, N; Kimura, T; Miura, Y; Mouri, T; Ohzeki, T; Okamoto, H; Ota, K; Sone, M; Yamamoto, H | 1 |
Costa, T; Ogino, Y | 1 |
Nakagawa-Yagi, Y; Nakamura, H; Saito, Y; Takada, Y | 1 |
Leli, U; Parker, PJ; Shea, TB | 1 |
Agoston, DV; Colburn, S; Krajniak, KG; Waschek, JA | 1 |
Kaplan, BB; Kovacs, DM | 1 |
Cornaglia-Ferraris, P; Folghera, S; Lanciotti, M; Lucarelli, E; Montaldo, PG; Ponzoni, M | 1 |
McKinney, M; Robbins, M | 1 |
Larsson, C; Mau, S; Saermark, T; Simonsson, P | 1 |
Meyerson, G; Påhlman, S; Pfenninger, KH | 1 |
Boarder, MR; Wilkes, LC | 1 |
Tsuneishi, S | 1 |
Johansson, I; Nistér, M; Påhlman, S; Westermark, B | 1 |
Hammerling, U; Heikkilä, J; Nånberg, E; Påhlman, S; Parrow, V | 1 |
Nitsch, RM; Richardson, UI; Slack, BE; Wurtman, RJ | 1 |
Bonder, EM; Feder, HH; Gelfand, IM; Reboulleau, CP; Tint, IS; Vasiliev, JM | 1 |
Cataldo, A; Hauser, G; Leli, U; Nixon, RA; Shea, TB | 1 |
Ball, SG; McCormack, JG; Murphy, NP; Vaughan, PF | 1 |
Mitsui, K; Nagai, Y; Tsuji, S; Yamazaki, M | 1 |
Carroll, JM; Goodman, HM; Joh, TH; Kim, KS; Kim, KT | 1 |
Felipo, V; Grisolía, S; Miñana, MD | 1 |
Beck, D; Favre, S; Gross, N | 1 |
Folkesson, R; Monstein, HJ | 1 |
Ball, SG; Murphy, NP; Vaughan, PF | 1 |
Chan, J; Greenberg, DA | 1 |
Bernards, R | 1 |
Baglioni, C; Bussolino, F; Camussi, G; Herrick-Davis, K | 1 |
Johansson, I; Lindgren, E; Meyerson, G; Påhlman, S; Schalling, M | 1 |
Grishchenko, AV; Pinchuk, GV; Pinchuk, LN | 1 |
Sandmann, J; Wurtman, RJ | 1 |
Agoston, DV; Bravo, DT; Waschek, JA | 1 |
Adachi, Y; Hatanaka, M; Ishii, K; Maki, M; Murachi, T | 1 |
Cioffi, CL; Fisher, SK | 1 |
el-Fakahany, EE; Lai, WS; Rogers, TB | 1 |
Bass, ES; Law, PY; Loh, HH; Louie, AK; Zhan, J | 1 |
Bielicki, JK; Considine, RV; Sherwin, JR; Simpson, LL | 1 |
Hall, K; Hammerling, U; Mattsson, ME; Mohall, E; Påhlman, S | 1 |
Abraham, R; Enloes, L; Kanba, KS; Kanba, S; Mackey, S; McKinney, M; Nomura, S; Pfenning, M; Richelson, E | 1 |
Brodeur, G; Hailat, N; Hanash, S; Melhem, R; Reynolds, CP; Seeger, RC; Strahler, J; Zhu, XX | 1 |
Girard, PR; Kuo, JF | 1 |
Akerman, KE; Heikkilä, JE | 1 |
Akerlind, G; Akerman, KE; Heikkilä, J; Jalava, AM; Pettit, GR | 1 |
Gnegy, ME; Mangels, LA | 1 |
Fischer-Colbrie, R; Floor, E; Laslop, A; Meyerson, G; Påhlman, S; Weiler, R; Winkler, H | 1 |
Imaizumi, T; Mizushima, A; Osugi, T; Uchida, S; Yoshida, H | 2 |
Akerman, KE; Jalonen, T | 1 |
Dawson, G; McAtee, P | 1 |
Neuman, T; Salonen, EM; Stephens, RW; Timmusk, T; Vaheri, A | 1 |
Benjamin, LA; Hart, DA; McGarry, RC | 1 |
Berwald-Netter, Y; Couraud, F; Dubois, JM; Houzet, E; Jourdon, P | 1 |
Billingsley, ML; Kincaid, RL; Pennypacker, KR; Polli, JW | 1 |
Bisiani, C; Clementi, F; Denis-Donini, S; Sher, E; Zanini, A | 1 |
Akerlind, G; Akerman, KE; Heikkilä, JE | 1 |
Billingsley, ML; Kuhn, DM; Pennypacker, KR | 1 |
Abrahamsson, L; Esscher, T; Jergil, B; Mattsson, M; Påhlman, S; Ruusala, AI | 1 |
Garin-Chesa, P; Rettig, WJ | 1 |
Blusztajn, JK; Liscovitch, M; Slack, BE; Wurtman, RJ | 1 |
Akerman, KE; Heikkilä, J | 1 |
LeRoith, D; Ota, A; Roberts, CT; Shen-Orr, Z | 1 |
Liles, WC; Nathanson, NM | 1 |
Fu, T; Nozawa, Y; Okano, Y | 1 |
Bourne, HR; Chang, FH; Hochhaus, G; Richards, ML; Sadée, W; Yu, VC | 1 |
Liscovitch, M | 1 |
Chen, KY; Liu, AY | 1 |
Enberg, G; Hall, K; Mattsson, ME; Påhlman, S; Ruusala, AI | 1 |
Chuang, DM | 1 |
Kanba, KS; Kanba, S; Richelson, E | 1 |
Serra, M; Smith, TL; Yamamura, HI | 1 |
el-Fakahany, EE; Lai, WS | 1 |
Daly, JW; Hollingsworth, EB | 1 |
Higashida, H; Klee, W; Nirenberg, M; Streaty, RA | 1 |
Hunter, DD; Liles, WC; Meier, KE; Nathanson, NM | 1 |
Akerman, KE; Andersson, LC; Heikkilä, JE; Kaila, K; Scott, IG | 1 |
Akerman, KE; Heikkilä, JE; Jalava, AM | 1 |
Eiden, LE; Hsu, CM; Waschek, JA | 1 |
Bjelfman, C; Hammerling, U; Påhlman, S | 1 |
Janik, P; Miłoszewska, J; Przybyszewska, M; Szaniawska, B | 1 |
Parker, PJ; Rodriguez-Pena, A; Rozengurt, E; Stabel, S; Young, S | 1 |
Adem, A; Mattsson, ME; Nordberg, A; Påhlman, S | 1 |
Biedler, JL; Old, LJ; Real, FX; Rettig, WJ; Spengler, BA | 1 |
Blusztajn, JK; Liscovitch, M; Slack, B; Wurtman, RJ | 1 |
Blusztajn, JK; Freese, A; Liscovitch, M; Wurtman, RJ | 1 |
1 review(s) available for tetradecanoylphorbol acetate and Neuroblastoma
Article | Year |
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Differentiation and survival influences of growth factors in human neuroblastoma.
Topics: Cell Differentiation; Growth Substances; Humans; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Neoplastic Stem Cells; Neuroblastoma; Phenotype; Protein Kinase C; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1995 |
243 other study(ies) available for tetradecanoylphorbol acetate and Neuroblastoma
Article | Year |
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Protein Kinase C Attenuates Insulin Signalling Cascade in Insulin-Sensitive and Insulin-Resistant Neuro-2a Cells.
Topics: Animals; Cell Line, Tumor; Enzyme Activation; Glucose; Glycogen Synthase Kinase 3 beta; Insulin; Insulin Resistance; Mice; Nerve Tissue Proteins; Neuroblastoma; Neurons; Protein Kinase C; Proto-Oncogene Proteins c-akt; Signal Transduction; Tetradecanoylphorbol Acetate | 2019 |
Cytokine receptor-like factor 1 (CRLF1) protects against 6-hydroxydopamine toxicity independent of the gp130/JAK signaling pathway.
Topics: Cell Differentiation; Cell Line, Tumor; Cytokine Receptor gp130; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Immunoblotting; Janus Kinase 1; Janus Kinase 2; Janus Kinases; Microscopy, Fluorescence; Neuroblastoma; Oxidopamine; Receptors, Cytokine; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Signal Transduction; Tetradecanoylphorbol Acetate; Tretinoin | 2013 |
Therapeutic concentrations of valproate but not amitriptyline increase neuropeptide Y (NPY) expression in the human SH-SY5Y neuroblastoma cell line.
Topics: Amitriptyline; Anticonvulsants; Cell Line, Tumor; Cell Survival; Gene Expression; Humans; Neuroblastoma; Neuropeptide Y; Tetradecanoylphorbol Acetate; Valproic Acid | 2013 |
β-Arrestin1 and distinct CXCR4 structures are required for stromal derived factor-1 to downregulate CXCR4 cell-surface levels in neuroblastoma.
Topics: Arrestins; beta-Arrestins; Cell Line, Tumor; Cell Membrane; Chemokine CXCL12; Endocytosis; G-Protein-Coupled Receptor Kinase 2; GTP-Binding Proteins; Humans; Neoplasm Metastasis; Neuroblastoma; Pertussis Toxin; Phosphorylation; Protein Kinase C; Receptors, CXCR4; Tetradecanoylphorbol Acetate; Type C Phospholipases | 2014 |
Coordinated activation of AMP-activated protein kinase, extracellular signal-regulated kinase, and autophagy regulates phorbol myristate acetate-induced differentiation of SH-SY5Y neuroblastoma cells.
Topics: AMP-Activated Protein Kinases; Autophagy; Autophagy-Related Protein 7; Autophagy-Related Protein-1 Homolog; Cell Differentiation; Cell Line, Tumor; Dopamine Plasma Membrane Transport Proteins; Enzyme Activation; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation, Enzymologic; Humans; Intracellular Signaling Peptides and Proteins; Microtubule-Associated Proteins; Neuroblastoma; Protein Serine-Threonine Kinases; RNA Interference; Tetradecanoylphorbol Acetate; Ubiquitin-Activating Enzymes | 2015 |
The effect of differentiation agents on inflammatory and oxidative responses of the human neuroblastoma cell line SK-N-SH.
Topics: Antineoplastic Agents; Caspase 3; Caspase 7; Cell Differentiation; Cell Line, Tumor; Cytokines; Free Radicals; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Inflammation; Neuroblastoma; Neurons; Nitric Oxide; Nitrites; Oxidative Stress; Oxygen; Phenotype; Tetradecanoylphorbol Acetate; Tretinoin | 2015 |
Analysis of the Catecholaminergic Phenotype in Human SH-SY5Y and BE(2)-M17 Neuroblastoma Cell Lines upon Differentiation.
Topics: Catecholamines; Cell Differentiation; Cell Line, Tumor; Humans; Neuroblastoma; Staurosporine; Tetradecanoylphorbol Acetate; Tretinoin | 2015 |
Altered sensitivity to ellagic acid in neuroblastoma cells undergoing differentiation with 12-O-tetradecanoylphorbol-13-acetate and all-trans retinoic acid.
Topics: Apoptosis; Cell Differentiation; Cell Line, Tumor; Cell Survival; Ellagic Acid; Flow Cytometry; Humans; In Situ Nick-End Labeling; Integrins; Neuroblastoma; Proto-Oncogene Proteins c-bcl-2; Tetradecanoylphorbol Acetate; Tretinoin; Up-Regulation | 2015 |
Concomitant activation of adenylyl cyclase suppresses the opposite influences of CB(1) cannabinoid receptor agonists on tyrosine hydroxylase expression.
Topics: Adenylyl Cyclases; Animals; Cannabinoid Receptor Modulators; Cannabinoids; Cell Line, Tumor; Colforsin; Cyclohexanols; DNA Primers; Dronabinol; Enzyme Activation; Excitatory Amino Acid Antagonists; Genes, Reporter; Luciferases; Mice; Neuroblastoma; Pertussis Toxin; Polymerase Chain Reaction; Receptor, Cannabinoid, CB1; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Tyrosine 3-Monooxygenase | 2009 |
A disintegrin and metalloproteinase (ADAM)-mediated ectodomain shedding of ADAM10.
Topics: ADAM Proteins; ADAM10 Protein; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Arginine; Cell Line; Disintegrins; Enzyme Inhibitors; Humans; Membrane Proteins; Metalloproteases; Mutation; Neuroblastoma; Peptides; Phosphoinositide Phospholipase C; Protein Structure, Tertiary; Protein Transport; RNA, Small Interfering; Tetradecanoylphorbol Acetate; Transfection | 2009 |
Trichlorfon induces apoptosis in SH-SY5Y neuroblastoma cells via the endoplasmic reticulum?
Topics: Apoptosis; Blotting, Western; Calcium; Cell Line, Tumor; Cholinesterase Inhibitors; Endoplasmic Reticulum; Flow Cytometry; Humans; Microscopy, Fluorescence; Neuroblastoma; Tetradecanoylphorbol Acetate; Trichlorfon | 2009 |
Silencing Nogo-A promotes functional recovery in demyelinating disease.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; GAP-43 Protein; Gene Expression Regulation; Glycoproteins; Interferon-gamma; Interleukin-10; Lymphocytes; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myelin Basic Protein; Myelin Proteins; Myelin-Oligodendrocyte Glycoprotein; Neuroblastoma; Nogo Proteins; Peptide Fragments; RNA, Small Interfering; Spinal Cord; Tetradecanoylphorbol Acetate; Transfection | 2010 |
Protein kinase C stabilizes X-linked inhibitor of apoptosis protein (XIAP) through phosphorylation at Ser(87) to suppress apoptotic cell death.
Topics: Alzheimer Disease; Antineoplastic Agents, Phytogenic; Apoptosis; Brain; Cell Death; Cell Line, Tumor; Etoposide; Humans; Neuroblastoma; Neurons; Phosphorylation; Protein Kinase C; Serine; Tetradecanoylphorbol Acetate; Transfection; X-Linked Inhibitor of Apoptosis Protein | 2011 |
Regulation of neuroblastoma differentiation by forkhead transcription factors FOXO1/3/4 through the receptor tyrosine kinase PDGFRA.
Topics: Animals; Base Sequence; Cell Cycle Proteins; Cell Differentiation; Cell Line, Tumor; Forkhead Box Protein O1; Forkhead Box Protein O3; Forkhead Transcription Factors; Gene Expression Regulation, Neoplastic; Humans; Mice; Molecular Sequence Data; Neuroblastoma; Promoter Regions, Genetic; Receptor, Platelet-Derived Growth Factor alpha; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription, Genetic | 2012 |
Orphanin FQ/nociceptin-mediated desensitization of opioid receptor-like 1 receptor and mu opioid receptors involves protein kinase C: a molecular mechanism for heterologous cross-talk.
Topics: Alkaloids; Benzophenanthridines; beta-Adrenergic Receptor Kinases; Cell Membrane; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enzyme Inhibitors; G-Protein-Coupled Receptor Kinase 3; Humans; Neuroblastoma; Nociceptin; Nociceptin Receptor; Oligodeoxyribonucleotides, Antisense; Opioid Peptides; Phenanthridines; Protein Kinase C; Protein Serine-Threonine Kinases; Receptor Cross-Talk; Receptors, Opioid; Receptors, Opioid, mu; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2002 |
Malignant rhabdoid tumor shows incomplete neural characteristics as revealed by expression of SNARE complex.
Topics: Blotting, Western; Cell Differentiation; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; In Situ Hybridization; Membrane Proteins; Neuroblastoma; Reverse Transcriptase Polymerase Chain Reaction; Rhabdoid Tumor; SNARE Proteins; Syntaxin 1; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vesicular Transport Proteins | 2002 |
Interaction of palmitoylcarnitine with protein kinase C in neuroblastoma NB-2a cells.
Topics: Animals; Cell Differentiation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Mice; Neoplasm Proteins; Nerve Tissue Proteins; Neuroblastoma; Palmitoylcarnitine; Phosphorylation; Protein Kinase C; Protein Processing, Post-Translational; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2003 |
Role of protein kinase Calpha in the regulated secretion of the amyloid precursor protein.
Topics: Amyloid beta-Protein Precursor; Carbachol; Carcinogens; Cholinergic Agents; Humans; Isoenzymes; Neuroblastoma; Neurons; Protein Kinase C; Protein Kinase C-alpha; Receptors, Cholinergic; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 2003 |
Malignant rhabdoid tumor shows a unique neural differentiation as distinct from neuroblastoma.
Topics: Cell Differentiation; Chromogranin A; Chromogranins; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; In Situ Hybridization; Neoplasm Proteins; Nerve Tissue Proteins; Neuroblastoma; Neurofilament Proteins; Neurons; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; Rhabdoid Tumor; RNA, Messenger; RNA, Neoplasm; Synapsins; Tetradecanoylphorbol Acetate; Transcription Factors; Tumor Cells, Cultured | 2003 |
Attenuation of signal flow from P2Y6 receptor by protein kinase C-alpha in SK-N-BE(2)C human neuroblastoma cells.
Topics: Bradykinin; Calcium; Cell Differentiation; Cholinergic Agonists; Enzyme Activation; Humans; Inositol 1,4,5-Trisphosphate; Neuroblastoma; Nucleotides; Pertussis Toxin; Protein Kinase C; Protein Kinase C-alpha; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured; Uridine Diphosphate; Uridine Triphosphate | 2003 |
Induced differentiation affords neuroblastoma cells protection from hypoxic injury.
Topics: Cell Differentiation; Cell Division; Cell Hypoxia; Cell Survival; Humans; Models, Biological; Neuroblastoma; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 2003 |
Identification of signal transduction pathways that modulate dibutyryl cyclic adenosine monophosphate activation of stanniocalcin gene expression in neuroblastoma cells.
Topics: Animals; Antineoplastic Agents; Bucladesine; Calcium; Cell Differentiation; Drug Interactions; Gene Expression Regulation; Glycoproteins; Hormones; Mice; Neuroblastoma; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured; Xanthenes; Xanthones | 2003 |
Impaired degradation of PKCalpha by proteasome in a cellular model of Huntington's disease.
Topics: Animals; Cell Membrane; Cysteine Endopeptidases; Cytosol; Down-Regulation; Electrophoresis, Polyacrylamide Gel; Humans; Huntington Disease; Mice; Multienzyme Complexes; Mutation; Neuroblastoma; Precipitin Tests; Proteasome Endopeptidase Complex; Protein Kinase C; Protein Kinase C-alpha; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Ubiquitin | 2003 |
Egr-1 upregulates the Alzheimer's disease presenilin-2 gene in neuronal cells.
Topics: Base Sequence; Binding Sites; Cell Line; Cell Line, Tumor; DNA; DNA-Binding Proteins; Early Growth Response Protein 1; Electrophoretic Mobility Shift Assay; Gene Expression Regulation; Humans; Immediate-Early Proteins; Luciferases; Membrane Proteins; Molecular Sequence Data; Mutagenesis; Neuroblastoma; Presenilin-2; Promoter Regions, Genetic; Protein Binding; Recombinant Fusion Proteins; Sp1 Transcription Factor; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription Initiation Site; Transcription, Genetic | 2003 |
A possible role for p190RhoGAP in PKCepsilon-induced morphological effects.
Topics: Animals; Binding Sites; CHO Cells; Cricetinae; Cricetulus; DNA-Binding Proteins; GTPase-Activating Proteins; Guanine Nucleotide Exchange Factors; Humans; Mice; Nerve Growth Factor; Neurites; Neuroblastoma; NIH 3T3 Cells; Nuclear Proteins; Phosphorylation; Protein Binding; Protein Kinase C; Protein Kinase C-epsilon; Protein Structure, Tertiary; Repressor Proteins; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2004 |
Regulation of the human corticotropin-releasing-hormone gene promoter activity by antidepressant drugs in Neuro-2A and AtT-20 cells.
Topics: Animals; Antidepressive Agents; Cell Differentiation; Cell Line; Cell Survival; Chloramphenicol O-Acetyltransferase; Colforsin; Corticotropin-Releasing Hormone; Dexamethasone; Dose-Response Relationship, Drug; Drug Interactions; Gene Expression Regulation; Glucocorticoids; Humans; Mice; Molecular Biology; Neuroblastoma; Pituitary Gland; Potassium Chloride; Promoter Regions, Genetic; Tetradecanoylphorbol Acetate; Transfection | 2004 |
Neuroblastoma cells with overexpressed MYCN retain their capacity to undergo neuronal differentiation.
Topics: Brain-Derived Neurotrophic Factor; Cell Differentiation; Cell Line, Tumor; Genes, myc; Humans; Neuroblastoma; Neurons; Sympathetic Nervous System; Tetradecanoylphorbol Acetate; Tretinoin | 2004 |
Presenilin expression during induced differentiation of the human neuroblastoma SH-SY5Y cell line.
Topics: Brain Neoplasms; Cell Differentiation; Cell Line, Tumor; Exons; Fetus; Humans; Immunoblotting; Immunohistochemistry; Membrane Proteins; Mutation; Neuroblastoma; Presenilin-1; Tetradecanoylphorbol Acetate; Transfection; Tretinoin | 2004 |
Manipulation of PrPres production in scrapie-infected neuroblastoma cells.
Topics: Animals; Animals, Newborn; Antineoplastic Agents; Blotting, Western; Brain; Carcinogens; Cell Count; Cell Line, Tumor; Cell Survival; Cells, Cultured; Coculture Techniques; Dose-Response Relationship, Drug; Drug Interactions; Endopeptidase K; Enzyme-Linked Immunosorbent Assay; Glycosylation; Humans; Interleukin-6; Mice; Microglia; Neuroblastoma; Prions; PrPSc Proteins; Scrapie; Tetradecanoylphorbol Acetate; Tetrazolium Salts; Thiazoles; Transfection; Tretinoin | 2004 |
Neuronal cell lines transfected with the dopamine D2 receptor gene promoter as a model for studying the effects of antidepressant drugs.
Topics: Animals; Antidepressive Agents; Cell Line, Tumor; Colforsin; Dose-Response Relationship, Drug; Gene Expression Regulation; Humans; Neuroblastoma; Neurons; Promoter Regions, Genetic; Rats; Receptors, Dopamine D2; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Tretinoin | 2004 |
Genetically encoded FRET probe for PKC activity based on pleckstrin.
Topics: Bacterial Proteins; Blood Proteins; Bradykinin; Cell Line, Tumor; Fluorescence Resonance Energy Transfer; Green Fluorescent Proteins; HeLa Cells; Histamine; Humans; Luminescent Proteins; Models, Molecular; Neuroblastoma; Neurons; Peptide Fragments; Phosphoproteins; Phosphorylation; Protein Conformation; Protein Kinase C; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate | 2004 |
Involvement of dopamine D(2)/D(3) receptors and BDNF in the neuroprotective effects of S32504 and pramipexole against 1-methyl-4-phenylpyridinium in terminally differentiated SH-SY5Y cells.
Topics: 1-Methyl-4-phenylpyridinium; Antibodies; Benzothiazoles; Brain-Derived Neurotrophic Factor; Cell Differentiation; Cell Line; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Enzyme Inhibitors; Humans; Neuroblastoma; Neurons; Neuroprotective Agents; Oxazines; Pramipexole; Receptors, Dopamine D2; Receptors, Dopamine D3; Tetradecanoylphorbol Acetate; Thiazoles; Tretinoin | 2004 |
WAVE3 promotes cell motility and invasion through the regulation of MMP-1, MMP-3, and MMP-9 expression.
Topics: Actins; Adenocarcinoma; Cell Line, Tumor; Cell Movement; Down-Regulation; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Imidazoles; Matrix Metalloproteinase 1; Matrix Metalloproteinase 3; Matrix Metalloproteinase 9; Microfilament Proteins; Neoplasm Invasiveness; Neuroblastoma; p38 Mitogen-Activated Protein Kinases; Pyridines; RNA, Messenger; RNA, Small Interfering; Tetradecanoylphorbol Acetate; Time Factors; Wiskott-Aldrich Syndrome Protein Family | 2005 |
MAG induces regulated intramembrane proteolysis of the p75 neurotrophin receptor to inhibit neurite outgrowth.
Topics: Amyloid Precursor Protein Secretases; Animals; Animals, Newborn; Aspartic Acid Endopeptidases; Blotting, Western; Cells, Cultured; Cerebellum; Cricetinae; Cricetulus; Drug Interactions; Endopeptidases; Enzyme Activation; Enzyme Inhibitors; Membrane Proteins; Myelin-Associated Glycoprotein; Neural Inhibition; Neurites; Neuroblastoma; Neurons; Oligopeptides; Protein Structure, Tertiary; Rats; Receptor, Nerve Growth Factor; Receptors, Nerve Growth Factor; Recombinant Fusion Proteins; rho GTP-Binding Proteins; Tetradecanoylphorbol Acetate; Transfection | 2005 |
Regulation of neurite outgrowth in N1E-115 cells through PDZ-mediated recruitment of diacylglycerol kinase zeta.
Topics: Adenoviridae; Amino Acid Motifs; Animals; Binding Sites; Cell Line, Tumor; Diacylglycerol Kinase; Dystrophin-Associated Proteins; Enzyme Activation; Gene Expression Regulation; Glutathione Transferase; Mice; Microscopy, Confocal; Models, Biological; Models, Genetic; Mutation; Neurites; Neuroblastoma; Neurons; Phosphorylation; Protein Binding; Protein Kinase C; Protein Structure, Tertiary; rac1 GTP-Binding Protein; Recombinant Fusion Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors | 2005 |
Shedding of the amyloid precursor protein-like protein APLP2 by disintegrin-metalloproteinases.
Topics: ADAM Proteins; ADAM17 Protein; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Astrocytoma; Blotting, Western; Cattle; Cell Culture Techniques; Cell Differentiation; Cell Extracts; Cell Line; Cell Line, Tumor; Dipeptides; Disintegrins; Endopeptidases; Gene Expression Regulation; Humans; Metalloproteases; Mice; Mice, Transgenic; Mutagenesis; Nerve Tissue Proteins; Neuroblastoma; Protease Inhibitors; Solubility; Tetradecanoylphorbol Acetate; Tretinoin; Up-Regulation | 2005 |
12-O-tetradecanoyl-phorbol-13-acetate-dependent up-regulation of dopaminergic gene expression requires Ras and neurofibromin in human IMR-32 neuroblastoma.
Topics: Cell Line, Tumor; DNA-Binding Proteins; Dopamine; Enzyme Activation; Gene Expression Regulation; Genes, ras; Humans; Neuroblastoma; Neurofibromin 1; Nuclear Receptor Subfamily 4, Group A, Member 2; Protein Kinase C; Protein Kinase C-alpha; ras Proteins; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factors; Tyrosine 3-Monooxygenase | 2006 |
Regulation of endothelin-converting enzyme-1 expression in human neuroblastoma cells.
Topics: Aspartic Acid Endopeptidases; Carbachol; Cell Hypoxia; Cell Line, Tumor; Cholinergic Agonists; Endothelin-Converting Enzymes; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glucose Transporter Type 1; Humans; Hydrogen Peroxide; Metalloendopeptidases; Neuroblastoma; Oxidants; Oxidative Stress; Tetradecanoylphorbol Acetate | 2006 |
Regulation of N-acetylaspartate and N-acetylaspartylglutamate biosynthesis by protein kinase activators.
Topics: Aspartic Acid; Bucladesine; Cell Line, Tumor; Cyclic AMP-Dependent Protein Kinases; Dipeptides; Dose-Response Relationship, Drug; Enzyme Activation; Glutamine; Humans; Neuroblastoma; Protein Kinase C; Protein Kinases; Tetradecanoylphorbol Acetate; Time Factors | 2006 |
[Phosphorylation of PKCdelta participates in the toxicity of 6-hydroxydopamine on dopaminergic neuroblastoma cell].
Topics: Acetophenones; Benzopyrans; Blotting, Western; Carbazoles; Cell Line, Tumor; Cell Survival; Dopamine; Enzyme Activators; Humans; Indoles; Maleimides; Neuroblastoma; Oxidopamine; Phosphorylation; Protein Kinase C-delta; Signal Transduction; Tetradecanoylphorbol Acetate | 2006 |
Nonsteroidal anti-inflammatory drugs and ectodomain shedding of the amyloid precursor protein.
Topics: Alkaline Phosphatase; Amyloid beta-Protein Precursor; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Cell Line, Tumor; CHO Cells; Cricetinae; Cricetulus; Ibuprofen; Indomethacin; Kinetics; Neuroblastoma; PC12 Cells; Rats; Tetradecanoylphorbol Acetate | 2009 |
Kinetics and concentration effects of TPA-induced differentiation of cultured human neuroblastoma cells.
Topics: Caenorhabditis elegans Proteins; Carrier Proteins; Cell Differentiation; Cell Line; Humans; Kinetics; Neuroblastoma; Norepinephrine; Phorbols; Phosphopyruvate Hydratase; Protein Kinase C; Receptors, Cell Surface; Receptors, Drug; Tetradecanoylphorbol Acetate | 1983 |
Retinoic acid-induced differentiation of cultured human neuroblastoma cells: a comparison with phorbolester-induced differentiation.
Topics: Cell Differentiation; Cell Division; Cell Line; Humans; Neuroblastoma; Neurons; Norepinephrine; Phenotype; Phorbols; Phosphopyruvate Hydratase; Tetradecanoylphorbol Acetate; Tretinoin | 1984 |
Changes in inducibility of ornithine decarboxylase activity in differentiating human neuroblastoma cells.
Topics: Cell Differentiation; Cell Division; Cell Line; Enzyme Induction; Humans; Neuroblastoma; Ornithine Decarboxylase; Tetradecanoylphorbol Acetate; Tretinoin | 1984 |
Are there two different forms of neuroblastoma?
Topics: Cell Differentiation; Chromosome Aberrations; Humans; Neoplasm Regression, Spontaneous; Neuroblastoma; Tetradecanoylphorbol Acetate | 1982 |
Effects of phorbol ester tumor promoters and nerve growth factor on neurite outgrowth in cultured human neuroblastoma cells.
Topics: Animals; Axons; Cell Division; Cell Line; Chick Embryo; Ganglia, Sympathetic; Humans; Nerve Growth Factors; Neuroblastoma; Phorbols; Tetradecanoylphorbol Acetate | 1982 |
Phenotypic changes of human neuroblastoma cells in culture induced by 12-O-tetradecanoyl-phorbol-13-acetate.
Topics: Cell Division; Cell Line; Cells, Cultured; Cytoplasmic Granules; Epinephrine; Humans; In Vitro Techniques; Microscopy, Electron; Neuroblastoma; Norepinephrine; Phenotype; Phorbols; Phosphopyruvate Hydratase; Tetradecanoylphorbol Acetate | 1981 |
Regulation of nicotinic acetylcholine receptors on human neuroblastoma cells during differentiation.
Topics: Binding Sites; Bungarotoxins; Cell Differentiation; Cyclic AMP; Down-Regulation; Enzyme Activation; Humans; Iodine Radioisotopes; Kinetics; Neuroblastoma; Neurons; Protein Kinase C; Receptors, Nicotinic; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1995 |
Basic FGF and IGF-I promote differentiation of human SH-SY5Y neuroblastoma cells in culture.
Topics: Blotting, Northern; Cell Differentiation; Cell Division; Cell Line; Fibroblast Growth Factor 1; Fibroblast Growth Factor 2; GAP-43 Protein; Growth Substances; Humans; Insulin; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Intracellular Signaling Peptides and Proteins; Membrane Glycoproteins; Membrane Proteins; Myristoylated Alanine-Rich C Kinase Substrate; Nerve Growth Factors; Nerve Tissue Proteins; Neuroblastoma; Neuropeptides; Phosphorylation; Platelet-Derived Growth Factor; Protein Kinase C; Proteins; Recombinant Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Phosphorylation of Gi alpha 2 attenuates inhibitory adenylyl cyclase in neuroblastoma/glioma hybrid (NG-108-15) cells.
Topics: Adenylyl Cyclases; Enkephalin, Leucine-2-Alanine; Enzyme Activation; Ethers, Cyclic; Glioma; GTP-Binding Proteins; Hybrid Cells; Naphthalenes; Neuroblastoma; Okadaic Acid; Phorbols; Phosphorylation; Polycyclic Compounds; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Appearance of depolarization- and maitotoxin-induced [Ca2+]i elevation in single LAN-1 human neuroblastoma cells on exposure to retinoic acid.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Calcium; Cell Differentiation; Cytophotometry; Humans; Marine Toxins; Membrane Potentials; Neuroblastoma; Nimodipine; omega-Conotoxin GVIA; Oxocins; Peptides; Potassium; Tetradecanoylphorbol Acetate; Time Factors; Tretinoin; Tumor Cells, Cultured | 1994 |
Vasoactive intestinal polypeptide stimulates cyclic AMP production in mouse N1E-115 neuroblastoma cells: modulation by a protein kinase C activator and ionomycin.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Animals; Calcium; Carcinogens; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Enzyme Activation; Ionomycin; Isoquinolines; Kinetics; Mice; Neuroblastoma; Phorbol Esters; Piperazines; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vasoactive Intestinal Peptide | 1994 |
Regulation of corticotropin-releasing factor secretion and synthesis in the human neuroblastoma clones- BE(2)-M17 and BE(2)-C.
Topics: Colforsin; Corticotropin-Releasing Hormone; Dexamethasone; Enzyme Activation; Humans; Interleukin-1; Neuroblastoma; Neuropeptides; Neurotransmitter Agents; Protein Kinase C; Serotonin; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Expression of NOR-1 and its closely related members of the steroid/thyroid hormone receptor superfamily in human neuroblastoma cell lines.
Topics: Base Sequence; Cell Differentiation; Cell Line; Colforsin; Cycloheximide; DNA Primers; DNA-Binding Proteins; Gene Expression; Humans; Molecular Sequence Data; Nerve Tissue Proteins; Neuroblastoma; Nuclear Receptor Subfamily 4, Group A, Member 1; Nuclear Receptor Subfamily 4, Group A, Member 2; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Receptors, Thyroid Hormone; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Transcription Factors; Tumor Cells, Cultured | 1995 |
Tumor necrosis factor receptors in neuroblastoma SKNBE cells and their regulation by retinoic acid.
Topics: Blood Physiological Phenomena; Bucladesine; Cell Differentiation; Cell Division; Humans; Neuroblastoma; Receptors, Tumor Necrosis Factor; RNA, Messenger; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1995 |
Molecular species analysis of 1,2-diglycerides on phorbol ester stimulation of LA-N-1 neuroblastoma cells during proliferation and differentiation.
Topics: Cell Differentiation; Cell Division; Diglycerides; Humans; Neuroblastoma; Phospholipids; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured | 1995 |
Amyloid precursor protein processing is stimulated by metabotropic glutamate receptors.
Topics: Alanine; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Cell Line; Chelating Agents; Cycloleucine; Embryo, Mammalian; Fetus; Glioma; Glutamic Acid; Hippocampus; Humans; Indoles; Kidney; Kinetics; Maleimides; N-Methylaspartate; Neuroblastoma; Neurons; Neurotoxins; PC12 Cells; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Protein Kinase C; Protein Processing, Post-Translational; Pyrimidines; Quinacrine; Quisqualic Acid; Rats; Receptors, Metabotropic Glutamate; Recombinant Proteins; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1995 |
Muscarinic receptor-mediated induction of actin-driven lamellar protrusions in neuroblastoma cell somata and growth cones. Involvement of protein kinase C.
Topics: Acetylcholine; Actins; Alkaloids; Carbachol; Cell Size; Culture Media; Cytochalasin B; Fluorescent Dyes; Humans; Indoles; Maleimides; Neurites; Neuroblastoma; Protein Kinase C; Receptors, Muscarinic; Receptors, Nicotinic; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured | 1995 |
Different regulatory patterns of M1 and M2 muscarinic receptor subtype RNA in SH-SY5Y human neuroblastoma induced by phorbol ester or DMSO.
Topics: Blotting, Northern; Dimethyl Sulfoxide; Enzyme Activation; Humans; Isoenzymes; Neuroblastoma; Protein Kinase C; Receptors, Muscarinic; RNA; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Nicotinic receptor-mediated release of noradrenaline in the human neuroblastoma SH-SY5Y.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Calcium; Cell Membrane; Dimethylphenylpiperazinium Iodide; Fura-2; Humans; Membrane Potentials; Neuroblastoma; Nifedipine; Norepinephrine; Receptors, Nicotinic; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Stimulation of tyrosine phosphorylation and mitogen-activated-protein (MAP) kinase activity in human SH-SY5Y neuroblastoma cells by carbachol.
Topics: Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; Enzyme Activation; Epidermal Growth Factor; Humans; Neuroblastoma; Phosphorylation; Phosphotyrosine; Protein Kinase C; Protein Kinases; Receptors, Muscarinic; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine | 1993 |
Phospholipase D does not mediate alcohol inhibition of [3H]-noradrenaline release from SH-SY5Y cells.
Topics: Bradykinin; Butanols; Carbachol; Cell Line; Humans; Ionomycin; Kinetics; Methacholine Chloride; Neuroblastoma; Norepinephrine; Phosphates; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipase D; Phospholipids; Potassium; Tetradecanoylphorbol Acetate; Tritium; Tumor Cells, Cultured | 1994 |
Transcriptional vs. posttranscriptional control of neuropeptide Y gene expression.
Topics: Animals; Colforsin; Dichlororibofuranosylbenzimidazole; Drug Stability; Gene Expression Regulation; Neuroblastoma; Neuropeptide Y; PC12 Cells; Promoter Regions, Genetic; Protein Processing, Post-Translational; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1995 |
The role of protein kinase C in inducing Alzheimer's A68 protein expression in the culture of human neuroblastoma cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Antibodies, Monoclonal; Humans; Immunoblotting; Immunochemistry; Isoquinolines; Nerve Tissue Proteins; Neuroblastoma; Piperazines; Protein Kinase C; Sulfonamides; tau Proteins; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Cyclic AMP-dependent protein kinase regulates basal and cyclic AMP-stimulated but not phorbol ester-stimulated transcription of the tyrosine hydroxylase gene.
Topics: Base Sequence; Carrier Proteins; Chloramphenicol O-Acetyltransferase; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; DNA; Gene Expression Regulation; Humans; Intracellular Signaling Peptides and Proteins; Molecular Sequence Data; Neuroblastoma; Protein Kinase C; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Tumor Cells, Cultured; Tyrosine 3-Monooxygenase | 1994 |
Modulation of adenylylcyclase by protein kinase C in human neurotumor SK-N-MC cells: evidence that the alpha isozyme mediates both potentiation and desensitization.
Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Alkaloids; Aluminum Compounds; Animals; Brain; Cell Line; Cell Membrane; Cholera Toxin; Colforsin; Cyclic AMP; Dopamine; Drug Synergism; Fluorides; GTP-Binding Proteins; Humans; Isoenzymes; Isoproterenol; Kinetics; Manganese; Neuroblastoma; Neuropeptide Y; Propanolamines; Protein Kinase C; Rats; Sphingosine; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Differential expression of MARCKS and other calmodulin-binding protein kinase C substrates in cultured neuroblastoma and glioma cells.
Topics: Amino Acid Sequence; Animals; Calmodulin; GAP-43 Protein; Gene Expression; Glioma; Hot Temperature; Humans; Intracellular Signaling Peptides and Proteins; Membrane Glycoproteins; Membrane Proteins; Mice; Molecular Sequence Data; Myristic Acid; Myristic Acids; Myristoylated Alanine-Rich C Kinase Substrate; Nerve Tissue Proteins; Neuroblastoma; Phosphorylation; Protein Kinase C; Proteins; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Differential nuclear localization of protein kinase C isoforms in neuroblastoma x glioma hybrid cells.
Topics: Animals; Cell Differentiation; Cell Nucleolus; Cell Nucleus; Cytoplasm; Fluorescent Antibody Technique; Glioma; Hybrid Cells; Isoenzymes; Neuroblastoma; Nuclear Envelope; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Fos and Jun form cell specific protein complexes at the neuropeptide tyrosine promoter.
Topics: Alkaloids; Base Sequence; Cell Differentiation; Humans; Molecular Sequence Data; Neuroblastoma; Neuropeptide Y; Promoter Regions, Genetic; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine | 1994 |
Degradation of protein kinase C alpha and its free catalytic subunit, protein kinase M, in intact human neuroblastoma cells and under cell-free conditions. Evidence that PKM is degraded by mM calpain-mediated proteolysis at a faster rate than PKC.
Topics: Calpain; Cell-Free System; Humans; In Vitro Techniques; Isoenzymes; Neuroblastoma; Protein Kinase C; Protein Kinase C-alpha; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured | 1994 |
Characterization of the gap junction protein, connexin45.
Topics: Animals; Antibody Specificity; Carcinoma, Hepatocellular; Cell Line; Cell Line, Transformed; Connexin 43; Connexins; Cricetinae; Fluorescent Antibody Technique; Gap Junctions; Humans; Kidney; Liver Neoplasms; Membrane Proteins; Mice; Muscle, Smooth, Vascular; Myocardium; Neuroblastoma; Phosphorylation; Precipitin Tests; Rats; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Measurement of changes in functional muscarinic acetylcholine receptor density in single neuroblastoma cells using calcium release kinetics.
Topics: Animals; Calcium; Carbachol; Fura-2; Histamine; Kinetics; Mice; Neuroblastoma; Receptors, Histamine H1; Receptors, Muscarinic; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Transduction of retinoic acid and gamma-interferon signal for intercellular adhesion molecule-1 expression on human tumor cell lines: evidence for the late-acting involvement of protein kinase C inactivation.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Cell Adhesion Molecules; Enzyme Activation; Glioma; Humans; Intercellular Adhesion Molecule-1; Interferon-gamma; Isoquinolines; Neuroblastoma; Piperazines; Protein Kinase C; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1993 |
Mu opiate receptor down-regulation by morphine and up-regulation by naloxone in SH-SY5Y human neuroblastoma cells.
Topics: Amino Acid Sequence; Cell Differentiation; Dose-Response Relationship, Drug; Down-Regulation; Humans; Kinetics; Molecular Sequence Data; Morphine; MSH Release-Inhibiting Hormone; Naloxone; Neuroblastoma; Pentazocine; Quinuclidinyl Benzilate; Receptors, Muscarinic; Receptors, Opioid, mu; Temperature; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured; Up-Regulation | 1993 |
Activation of the human NPY gene during neuroblastoma cell differentiation: induced transcriptional activities of AP-1 and AP-2.
Topics: Base Sequence; Cell Differentiation; Gene Expression Regulation, Neoplastic; Genes, fos; Genes, jun; Humans; In Vitro Techniques; Molecular Sequence Data; Neuroblastoma; Phenotype; Protein Kinase C; Proto-Oncogene Proteins c-jun; RNA, Messenger; Tetradecanoylphorbol Acetate; Transfection | 1994 |
Bradykinin-evoked release of [3H]noradrenaline from the human neuroblastoma SH-SY5Y.
Topics: Bradykinin; Calcium; Clone Cells; Dose-Response Relationship, Drug; Humans; Kinetics; Membrane Potentials; Neuroblastoma; Norepinephrine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Y2 receptors for neuropeptide Y are coupled to three intracellular signal transduction pathways in a human neuroblastoma cell line.
Topics: Angiotensin II; Benzoquinones; Bradykinin; Calcium; Cyclic AMP; Humans; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Lactams, Macrocyclic; Neuroblastoma; Neuropeptide Y; Pertussis Toxin; Potassium; Quinones; Receptors, Neuropeptide Y; Rifabutin; Second Messenger Systems; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1994 |
Activation of nuclear factor kappa B in human neuroblastoma cell lines.
Topics: Animals; Base Sequence; Cell Differentiation; Cell Line; Chloramphenicol O-Acetyltransferase; Humans; Molecular Sequence Data; Nerve Growth Factors; Neuroblastoma; NF-kappa B; Nuclear Proteins; Oligodeoxyribonucleotides; PC12 Cells; Protein Kinase C; Recombinant Proteins; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Tretinoin; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1994 |
Protein kinase C subtypes associated with the regulation of noradrenaline release in human SH-SY5Y neuroblastoma cells.
Topics: Carbachol; Cell Line; Humans; Indoles; Isoenzymes; Kinetics; Maleimides; Neuroblastoma; Norepinephrine; Potassium; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Tyrosine kinase-dependent suppression of a potassium channel by the G protein-coupled m1 muscarinic acetylcholine receptor.
Topics: Amino Acid Sequence; Animals; Brain; Calcimycin; Calcium; Cell Line; Embryo, Mammalian; Embryo, Nonmammalian; Female; Genistein; GTP-Binding Proteins; Humans; Isoflavones; Kidney; Kinetics; Membrane Potentials; Molecular Sequence Data; Mutagenesis, Site-Directed; Myocardium; Neuroblastoma; Oocytes; Potassium Channel Blockers; Potassium Channels; Protein Kinase C; Protein-Tyrosine Kinases; Receptors, Muscarinic; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured; Xenopus | 1993 |
Testosterone and progesterone metabolism in the human neuroblastoma cell line SH-SY5Y.
Topics: 20-alpha-Dihydroprogesterone; 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific); 3-Hydroxysteroid Dehydrogenases; 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Biotransformation; Cell Differentiation; Cell Line; Dihydrotestosterone; Humans; Kinetics; Neuroblastoma; Progesterone; Testosterone; Tetradecanoylphorbol Acetate; Time Factors; Tretinoin; Tumor Cells, Cultured | 1993 |
Inhibition of neurite outgrowth in neuroblastoma cells by sphingosine.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Axons; Blood; Culture Media; Isoquinolines; Mice; Neuroblastoma; Piperazines; Protein Kinase C; Sphingosine; Swine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
The selective protein kinase C inhibitor GF 109203X inhibits phorbol ester-induced morphological and functional differentiation of SH-SY5Y human neuroblastoma cells.
Topics: Blotting, Northern; Cell Differentiation; Cell Line; Dose-Response Relationship, Drug; GAP-43 Protein; Gene Expression; Genes, fos; Humans; Indoles; Kinetics; Maleimides; Membrane Glycoproteins; Molecular Weight; Nerve Tissue Proteins; Neurites; Neuroblastoma; Neuropeptide Y; Phosphoproteins; Phosphorylation; Protein Kinase C; Proto-Oncogene Mas; Proto-Oncogene Proteins c-fos; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Possible involvement of the base exchange enzymes in the phospholipid metabolism in LAN-2 cells.
Topics: Choline; Ethanolamine; Ethanolamines; Humans; Neuroblastoma; Phospholipids; Serine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Desensitization of acetylcholine induced inositol 1,4,5-trisphosphate formation in neuroblastoma SH-SY5Y cells following repetitive acetylcholine stimulations.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetylcholine; Alkaloids; Animals; Down-Regulation; Enzyme Activation; Humans; Inosine Triphosphate; Isoquinolines; Neuroblastoma; PC12 Cells; Phosphatidylinositols; Piperazines; Protein Kinase C; Second Messenger Systems; Signal Transduction; Staurosporine; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Suppression by [D-Pen2, D-Pen5]enkephalin on cyclic AMP dependent protein kinase-induced, but not protein kinase C-induced increment of intracellular free calcium in NG108-15 cells.
Topics: Analgesics; Animals; Bucladesine; Calcium; Calcium Channels; Colforsin; Depression, Chemical; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Glioma; Hybrid Cells; Intracellular Fluid; Mice; Neuroblastoma; Potassium Chloride; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Rats; Receptors, Opioid, delta; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Enhanced c-fos expression after intracellular iron deprivation.
Topics: Creatine Kinase; Cytosol; Deferoxamine; Gene Expression Regulation; Genes, fos; Iron; Neuroblastoma; Protein Kinase C; Proto-Oncogene Proteins c-fos; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Regulation of Bcl-2 oncoprotein levels with differentiation of human neuroblastoma cells.
Topics: Antineoplastic Agents; Carcinogens; Cell Differentiation; Cell Division; Cell Line; Cell Survival; Clone Cells; Drug Resistance; Gene Expression Regulation, Neoplastic; Humans; Kinetics; Neuroblastoma; Oncogenes; Phorbol Esters; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Tetradecanoylphorbol Acetate; Time Factors; Transfection; Tretinoin; Tumor Cells, Cultured | 1993 |
Phosphatidylethanol affects inositol 1,4,5-trisphosphate levels in NG108-15 neuroblastoma x glioma hybrid cells.
Topics: Animals; Bradykinin; Dose-Response Relationship, Drug; Ethanol; Glioma; Glycerophospholipids; Hybrid Cells; Inositol 1,4,5-Trisphosphate; Kinetics; Neuroblastoma; Phosphatidic Acids; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors | 1993 |
Dissociation of phosphorylation and translocation of a myristoylated protein kinase C substrate (MARCKS protein) in C6 glioma and N1E-115 neuroblastoma cells.
Topics: Animals; Biological Transport; Calcium; Calmodulin; Cell Membrane; Cytosol; Drug Stability; Glioma; Hot Temperature; Hydrogen-Ion Concentration; Intracellular Signaling Peptides and Proteins; Kinetics; Membrane Proteins; Mice; Myristic Acid; Myristic Acids; Myristoylated Alanine-Rich C Kinase Substrate; Neuroblastoma; Phosphorylation; Protein Kinase C; Proteins; Rats; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Protein kinase C-alpha but not protein kinase C-epsilon is differentially down-regulated by bryostatin 1 and tetradecanoyl phorbol 13-acetate in SH-SY5Y human neuroblastoma cells.
Topics: Biological Transport; Bryostatins; Cell Differentiation; Cytosol; Down-Regulation; Enzyme Activation; Humans; Isoenzymes; Lactones; Macrolides; Neuroblastoma; Phosphorylation; Protein Kinase C; Substrate Specificity; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Protein kinase inhibitor, staurosporine, induces a mature neuronal phenotype in SH-SY5Y human neuroblastoma cells through an alpha-, beta-, and zeta-protein kinase C-independent pathway.
Topics: Alkaloids; Bryostatins; Cell Differentiation; Cellular Senescence; Gene Expression; Genes, fos; Humans; Lactones; Macrolides; Neuroblastoma; Neurons; Phenotype; Phosphorylation; Protein Kinase C; Protein Kinase Inhibitors; Proto-Oncogene Mas; Staurosporine; Subcellular Fractions; Substrate Specificity; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Identification of a rapidly dephosphorylating 95-kDa protein as elongation factor 2 during 8-Br-cAMP treatment of N1E115 neuroblastoma cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amino Acid Sequence; Animals; Cell Differentiation; Cyclic AMP-Dependent Protein Kinases; Mice; Molecular Sequence Data; Molecular Weight; Nerve Tissue Proteins; Neuroblastoma; Neurons; Peptide Elongation Factor 2; Peptide Elongation Factors; Phosphoproteins; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Thyroid hormones stabilize acetylcholinesterase mRNA in neuro-2A cells that overexpress the beta 1 thyroid receptor.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 8-Bromo Cyclic Adenosine Monophosphate; Acetylcholinesterase; Animals; Cell Line; Dichlororibofuranosylbenzimidazole; Enzyme Inhibitors; Ethers, Cyclic; Humans; Isoquinolines; Kinetics; Mice; Naphthalenes; Neuroblastoma; Okadaic Acid; Phosphoprotein Phosphatases; Piperazines; Protein Binding; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Receptors, Thyroid Hormone; Recombinant Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Triiodothyronine; Tumor Cells, Cultured | 1995 |
The effect of the angiotensin II (AT1A) receptor stably transfected into human neuroblastoma SH-SY5Y cells on noradrenaline release and changes in intracellular calcium.
Topics: Angiotensin II; Animals; Brain Neoplasms; Calcium; Humans; Neuroblastoma; Norepinephrine; Protein Kinase C; Rats; Receptors, Angiotensin; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1995 |
Overexpression of MARCKS, but not protein kinase C-alpha, increases phorbol ester-stimulated synthesis of phosphatidylcholine in human SK-N-MC neuroblastoma cells.
Topics: Base Sequence; DNA, Complementary; Gene Expression Regulation, Enzymologic; Humans; Intracellular Signaling Peptides and Proteins; Isoenzymes; Membrane Proteins; Molecular Sequence Data; Myristoylated Alanine-Rich C Kinase Substrate; Neuroblastoma; Phosphatidylcholines; Phosphorylation; Protein Kinase C; Protein Kinase C-alpha; Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1996 |
Is actin polymerization relevant to neurosecretion? A study on neuroblastoma cells.
Topics: Actins; Carbachol; Cell Differentiation; Cell Line; Humans; Kinetics; Neuroblastoma; Norepinephrine; Tetradecanoylphorbol Acetate; Time Factors; Tretinoin; Tumor Cells, Cultured | 1996 |
Characterization of pituitary adenylate cyclase-activating polypeptide 38 (PACAP38)-, PACAP27-, and vasoactive intestinal peptide-stimulated responses in N1E-115 neuroblastoma cells.
Topics: Calcium; Carcinogens; Cyclic AMP; Iodine Radioisotopes; Ionomycin; Ionophores; Neurites; Neuroblastoma; Neuropeptides; Neurotransmitter Agents; Pituitary Adenylate Cyclase-Activating Polypeptide; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured; Vasoactive Intestinal Peptide | 1996 |
The GTPase-activating protein n-chimaerin cooperates with Rac1 and Cdc42Hs to induce the formation of lamellipodia and filopodia.
Topics: 3T3 Cells; Actins; Animals; cdc42 GTP-Binding Protein; Cell Cycle Proteins; Chimerin 1; Chlorocebus aethiops; Cytoskeleton; DNA, Complementary; Enzyme Activation; Fibroblasts; GTP Phosphohydrolases; GTP-Binding Proteins; Humans; Mice; Microinjections; Nerve Tissue Proteins; Neuroblastoma; Pseudopodia; rac GTP-Binding Proteins; Recombinant Fusion Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vinculin | 1996 |
Protein kinase C-epsilon is implicated in neurite outgrowth in differentiating human neuroblastoma cells.
Topics: Cell Differentiation; Down-Regulation; Enzyme Inhibitors; Growth Substances; Humans; Indoles; Isoenzymes; Maleimides; Neurites; Neuroblastoma; Neurons; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-epsilon; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1996 |
Ciliary neurotrophic factor regulates nicotinic acetylcholine receptors on human neuroblastoma cells.
Topics: Bungarotoxins; Ciliary Neurotrophic Factor; Dose-Response Relationship, Drug; Gene Expression Regulation; Genes, fos; Humans; Nerve Growth Factors; Nerve Tissue Proteins; Neuroblastoma; Receptors, Nicotinic; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1996 |
Phorbol ester stimulation of phosphatidylcholine synthesis in four cultured neural cell lines: correlations with expression of protein kinase C isoforms.
Topics: Animals; Blotting, Northern; Blotting, Western; Choline; Gene Expression; Glioma; Humans; Isoenzymes; Mice; Neuroblastoma; Oleic Acid; Oleic Acids; Phosphatidylcholines; Protein Kinase C; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Cholinergic stimulation of AP-1 and NF kappa B transcription factors is differentially sensitive to oxidative stress in SH-SY5Y neuroblastoma: relationship to phosphoinositide hydrolysis.
Topics: Carbachol; Cell Membrane; DNA; Enzyme Activation; Humans; Hydrogen Peroxide; Hydrolysis; Muscarinic Agonists; Neuroblastoma; NF-kappa B; Oxidative Stress; Phosphatidylinositols; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Tumor Cells, Cultured | 1996 |
H7, an inhibitor of protein kinase C, prevents serum-induced phosphorylation of Raf and MAP kinase in neuroblastoma cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Blood Physiological Phenomena; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Mice; Mitogen-Activated Protein Kinase 1; Neuroblastoma; Phosphorylation; Protein Kinase C; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1996 |
Translocation of the PKC isoforms present in the human neuroblastoma, SH-SY5Y, following short-term treatment with the phorbol ester, TPA.
Topics: Biological Transport, Active; GAP-43 Protein; Humans; Intracellular Signaling Peptides and Proteins; Isoenzymes; Membrane Glycoproteins; Membrane Proteins; Myristoylated Alanine-Rich C Kinase Substrate; Nerve Tissue Proteins; Neuroblastoma; Protein Kinase C; Proteins; Subcellular Fractions; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1996 |
Glycosaminoglycans in nerve injury: 1. Low doses of glycosaminoglycans promote neurite formation.
Topics: Animals; Cell Differentiation; Dose-Response Relationship, Drug; Glycosaminoglycans; Heparin; Nerve Growth Factors; Neurites; Neuroblastoma; Neurons; PC12 Cells; Rats; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1996 |
Activation of protein kinase C-alpha and translocation of the myristoylated alanine-rich C-kinase substrate correlate with phorbol ester-enhanced noradrenaline release from SH-SY5Y human neuroblastoma cells.
Topics: Alanine; Enzyme Activation; Humans; Intracellular Signaling Peptides and Proteins; Isoenzymes; Membrane Proteins; Myristoylated Alanine-Rich C Kinase Substrate; Neuroblastoma; Norepinephrine; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphorylation; Phosphotransferases; Protein Kinase C; Proteins; Subcellular Fractions; Substrate Specificity; Tetradecanoylphorbol Acetate; Tissue Distribution; Translocation, Genetic; Tumor Cells, Cultured | 1997 |
Opposing regulation of ciliary neurotrophic factor receptors on neuroblastoma cells by distinct differentiating agents.
Topics: Antineoplastic Agents; Binding Sites; Carcinogens; Cell Differentiation; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; Humans; Iodine Radioisotopes; Neuroblastoma; Phosphorylation; Protein Biosynthesis; Protein Kinase C; Protein Processing, Post-Translational; Receptor, Ciliary Neurotrophic Factor; Receptors, Nerve Growth Factor; RNA, Messenger; Sensitivity and Specificity; STAT3 Transcription Factor; Tetradecanoylphorbol Acetate; Trans-Activators; Transcription, Genetic; Tretinoin; Tumor Cells, Cultured | 1997 |
Do insulin-like growth factor binding proteins (IGFBPs) modulate the IGF-I growth promoting and differentiating effects in human neuroblastoma cells?
Topics: Animals; Antibodies, Monoclonal; Cell Count; Cell Differentiation; Cell Division; Culture Media, Serum-Free; Electrophoresis, Polyacrylamide Gel; GAP-43 Protein; Humans; Immune Sera; Immunoblotting; Insulin-Like Growth Factor Binding Proteins; Insulin-Like Growth Factor I; Membrane Glycoproteins; Mice; Microscopy, Phase-Contrast; Nerve Tissue Proteins; Neuroblastoma; Neurofilament Proteins; Peptide Fragments; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured | 1996 |
Expression of CD44 isoforms in neuroblastoma cells is regulated by PI 3-kinase and protein kinase C.
Topics: Carcinogens; Cell Adhesion; Enzyme Inhibitors; Humans; Hyaluronan Receptors; Hyaluronic Acid; Indoles; Insulin-Like Growth Factor I; Maleimides; Models, Molecular; Neuroblastoma; Phosphatidylinositol 3-Kinases; Phosphotransferases (Alcohol Group Acceptor); Platelet-Derived Growth Factor; Protein Kinase C; Signal Transduction; Surface Properties; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Up-Regulation | 1997 |
Neuronal differentiation in SH-SY5Y human neuroblastoma cells induces synthesis and secretion of tenascin and upregulation of alpha(v) integrin receptors.
Topics: Antigens, CD; Cell Differentiation; Fibronectins; Fluorescent Antibody Technique, Indirect; Gene Expression Regulation, Neoplastic; Humans; Integrin alphaV; Microscopy, Fluorescence; Neoplasm Proteins; Neuroblastoma; Neurons; Tenascin; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1997 |
Transcriptional regulation of intercellular adhesion molecule 1 by phorbol ester in human neuroblastoma cell line SK-N-SH involves jun- and fos-containing activator protein 1 site binding complex(es).
Topics: Cyclic AMP Response Element-Binding Protein; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Intercellular Adhesion Molecule-1; Neuroblastoma; NF-kappa B; Protein Binding; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Regulatory Sequences, Nucleic Acid; RNA, Messenger; TATA Box; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription, Genetic; Transcriptional Activation | 1997 |
Staurosporine differentiated human SH-SY5Y neuroblastoma cultures exhibit transient apoptosis and trophic factor independence.
Topics: Apoptosis; Aurintricarboxylic Acid; Calcium Channels; Cell Differentiation; Cell Survival; Electrophysiology; Enzyme Inhibitors; Humans; Ion Channel Gating; Nerve Growth Factors; Neuroblastoma; Neurons; Norepinephrine; Phenotype; Staurosporine; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1997 |
Plasma membrane alterations and cytoskeletal changes in apoptosis.
Topics: Actins; Annexin A5; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Membrane; Chromatin; Cytoskeleton; Ethylmaleimide; Humans; Keratins; Kinetin; Lung Neoplasms; Neuroblastoma; Phosphatidylserines; Purines; Roscovitine; Tetradecanoylphorbol Acetate; Tubulin; Tumor Cells, Cultured; Vimentin | 1997 |
P2Y receptor linked to phospholipase C: stimulation of neuro 2A cells by UTP and ATP and possible regulation by protein kinase C subtype epsilon.
Topics: Adenosine Triphosphate; Animals; Bradykinin; Hydrolysis; Isoenzymes; Mice; Neuroblastoma; Nucleotides; Pertussis Toxin; Phosphatidylinositols; Protein Kinase C; Receptors, Purinergic; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured; Type C Phospholipases; Uridine Triphosphate; Virulence Factors, Bordetella | 1997 |
Role of protein kinase C and second messengers in regulation of the norepinephrine transporter.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amino Acid Substitution; Animals; Bucladesine; Carrier Proteins; Cattle; Cells, Cultured; COS Cells; Cyclic AMP; Gene Expression Regulation; Humans; Neuroblastoma; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Protein Kinase C; Recombinant Proteins; Second Messenger Systems; Symporters; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1998 |
Regulation of mu opioid receptor mRNA levels by activation of protein kinase C in human SH-SY5Y neuroblastoma cells.
Topics: Enzyme Activation; Gene Expression Regulation; Humans; Neuroblastoma; Protein Kinase C; Receptors, Opioid, mu; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1997 |
Protein kinase C regulates adenosine A2a receptor mRNA expression in SH-SY5Y cells.
Topics: Adenosine; Cyclic AMP; Gene Expression Regulation; Humans; Neuroblastoma; Phenethylamines; Protein Kinase C; Receptor, Adenosine A2A; Receptors, Purinergic P1; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1997 |
Direct visualization of the translocation of the gamma-subspecies of protein kinase C in living cells using fusion proteins with green fluorescent protein.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Calcimycin; Calcium; CHO Cells; COS Cells; Cricetinae; Cytochalasin D; Glioma; Green Fluorescent Proteins; Hybrid Cells; Isoenzymes; Kinetics; Luminescent Proteins; Mice; Microscopy, Confocal; Molecular Sequence Data; Neuroblastoma; Protein Kinase C; Receptors, N-Methyl-D-Aspartate; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Transfection | 1997 |
A protein kinase C-activating phorbol ester enhances transcription of the human DBH gene through a cyclic AMP response element in SK-N-BE(2)C cells.
Topics: Base Sequence; Binding Sites; Chloramphenicol O-Acetyltransferase; Cyclic AMP; Dopamine beta-Hydroxylase; Humans; Mutagenesis, Site-Directed; Neuroblastoma; Point Mutation; Protein Kinase C; Recombinant Fusion Proteins; Regulatory Sequences, Nucleic Acid; RNA, Messenger; Sequence Deletion; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1997 |
Nitric oxide donor-induced p53-sensitive cell death is enhanced by Bcl-2 reduction in human neuroblastoma cells.
Topics: Animals; bcl-2-Associated X Protein; Bucladesine; Cell Death; Dimerization; DNA Fragmentation; Gene Expression; Genes, p53; Humans; Immunohistochemistry; Mice; Neuroblastoma; Nitric Oxide; Oxidation-Reduction; Penicillamine; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; S-Nitroso-N-Acetylpenicillamine; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 1998 |
NGF, cyclic AMP, and phorbol esters regulate oxytocin receptor gene transcription in SK-N-SH and MCF7 cells.
Topics: Animals; Brain; Breast Neoplasms; Cloning, Molecular; Colforsin; Cyclic AMP; DNA-Binding Proteins; Female; Humans; Nerve Growth Factors; Neuroblastoma; Promoter Regions, Genetic; Rats; Receptors, Oxytocin; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1998 |
N-Methyl-D-aspartate attenuates opioid receptor-mediated G protein activation and this process involves protein kinase C.
Topics: Animals; Cells, Cultured; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Enzyme Activation; GTP-Binding Proteins; Humans; Mice; Mutagenesis, Site-Directed; N-Methylaspartate; Neuroblastoma; Neurons; Phosphorylation; Protein Kinase C; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1998 |
Constitutive and cytokine-inducible expression of prion protein gene in human neural cell lines.
Topics: Astrocytoma; Brain; Brain Neoplasms; Cell Line; Cerebellum; Cytokines; Eye Neoplasms; Gene Expression Regulation; Humans; Interferon-gamma; Interleukin-1; Interleukin-10; Neuroblastoma; Neuroglia; Neurons; Polymerase Chain Reaction; Prions; Retinoblastoma; RNA, Messenger; Teratocarcinoma; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transforming Growth Factor beta; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1998 |
Overexpression of myristoylated alanine-rich C-kinase substrate enhances activation of phospholipase D by protein kinase C in SK-N-MC human neuroblastoma cells.
Topics: Calmodulin; Enzyme Activation; Gene Expression Regulation, Enzymologic; Glycerophospholipids; Golgi Apparatus; Humans; Indoles; Intracellular Signaling Peptides and Proteins; Isoenzymes; Maleimides; Membrane Proteins; Myristoylated Alanine-Rich C Kinase Substrate; Neuroblastoma; Phosphatidic Acids; Phosphatidylcholines; Phospholipase D; Protein Kinase C; Protein Kinase C-alpha; Proteins; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1998 |
Enhancement of beta-amyloid precursor protein transcription and expression by the soluble interleukin-6 receptor/interleukin-6 complex.
Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Protein Precursor; Antigens, CD; Base Sequence; Brain; Cytokine Receptor gp130; Fetal Proteins; Fibroblast Growth Factor 2; Gene Expression Regulation; Genes, Reporter; Humans; Interleukin-6; Lipopolysaccharides; Luciferases; Membrane Glycoproteins; Molecular Sequence Data; Neoplasm Proteins; Neuroblastoma; Neurons; Polymerase Chain Reaction; Receptors, Interleukin-6; Recombinant Fusion Proteins; RNA, Messenger; Solubility; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1998 |
The effect of cytochalasin D and colcemid on noradrenaline release in the human neuroblastoma SH-SY5Y.
Topics: Cytochalasin D; Demecolcine; Enzyme Activation; Ganglia; Humans; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Myristoylated Alanine-Rich C Kinase Substrate; Neuroblastoma; Norepinephrine; Protein Kinase C; Proteins; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1998 |
Down-regulation of protein kinase C alpha and gamma and enhanced TPA-induced neurite formation in DAN-transfected neuroblastoma cells.
Topics: 3T3 Cells; Animals; Blotting, Western; Calpain; Carrier Proteins; Cell Cycle Proteins; Cytokines; Dexamethasone; Down-Regulation; Fibroblasts; Humans; Isoenzymes; Mice; Microfilament Proteins; Molecular Weight; Nerve Tissue Proteins; Neurites; Neuroblastoma; Neurons; Protein Kinase C; Protein Kinase C-alpha; Proteins; Rats; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1998 |
Redistribution of F-actin and large dense-cored vesicles in the human neuroblastoma SH-SY5Y in response to secretagogues and protein kinase Calpha activation.
Topics: Actins; Calcimycin; Carbachol; Cell Membrane; Down-Regulation; Enzyme Activation; Humans; Ionophores; Isoenzymes; Liposomes; Neuroblastoma; Potassium; Protein Kinase C; Protein Kinase C-alpha; Secretory Rate; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1999 |
Activation of antioxidant/electrophile-responsive elements in IMR-32 human neuroblastoma cells.
Topics: Antioxidants; Butylated Hydroxyanisole; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Induction; Gene Expression Regulation, Neoplastic; Genes, Reporter; Humans; Hydroquinones; NAD(P)H Dehydrogenase (Quinone); Neuroblastoma; Neurons; Protein Kinase C; Regulatory Sequences, Nucleic Acid; Signal Transduction; Tetradecanoylphorbol Acetate; Transcriptional Activation; Tumor Cells, Cultured | 1999 |
Muscarinic M3 and epidermal growth factor receptors activate mutually inhibitory signaling cascades in human neuroblastoma SH-SY5Y cells.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Carbachol; Cell Adhesion Molecules; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; GRB2 Adaptor Protein; Humans; Neuroblastoma; Oncogene Protein v-cbl; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Proteins; Receptor, Muscarinic M3; Receptors, Muscarinic; Retroviridae Proteins, Oncogenic; Shc Signaling Adaptor Proteins; Signal Transduction; Src Homology 2 Domain-Containing, Transforming Protein 1; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1999 |
Human achaete-scute homologue 1 (HASH-1) is downregulated in differentiating neuroblastoma cells.
Topics: Basic Helix-Loop-Helix Transcription Factors; Blotting, Northern; Carcinoma, Small Cell; Carrier Proteins; Cell Differentiation; Cell Size; DNA-Binding Proteins; Down-Regulation; GAP-43 Protein; Growth Substances; Humans; Lung Neoplasms; Membrane Proteins; Neurites; Neuroblastoma; Neurons; Neuropeptide Y; Receptor, trkA; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription Factors; Transfection; Tretinoin; Tumor Cells, Cultured | 1999 |
Ciliary neurotrophic factor and phorbol ester each decrease selected STAT3 pools in neuroblastoma cells by proteasome-dependent mechanisms.
Topics: Ciliary Neurotrophic Factor; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Cytokines; DNA-Binding Proteins; Humans; Leupeptins; Multienzyme Complexes; Nerve Tissue Proteins; Neuroblastoma; Proteasome Endopeptidase Complex; Protein Kinase C; STAT2 Transcription Factor; STAT3 Transcription Factor; Tetradecanoylphorbol Acetate; Trans-Activators; Tumor Cells, Cultured | 1999 |
Continuous phosphorylation of GAP-43 and MARCKS by long-term TPA treatment in SK-N-SH human neuroblastoma cells.
Topics: Enzyme Activation; GAP-43 Protein; Humans; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Myristoylated Alanine-Rich C Kinase Substrate; Neuroblastoma; Phosphorylation; Protein Kinase C; Proteins; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured | 1999 |
Novel and classical protein kinase C isoforms have different functions in proliferation, survival and differentiation of neuroblastoma cells.
Topics: Cell Differentiation; Cell Division; Cell Survival; Fibroblast Growth Factor 2; GAP-43 Protein; Humans; Isoenzymes; Neuroblastoma; Neuropeptide Y; Protein Kinase C; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1999 |
Differentiation of neuroblastoma cells by phorbol esters and insulin-like growth factor 1 is associated with induction of retinoic acid receptor beta gene expression.
Topics: Carcinogens; Cell Differentiation; Gene Expression Regulation, Neoplastic; Humans; Insulin-Like Growth Factor I; Neuroblastoma; Promoter Regions, Genetic; Receptors, Retinoic Acid; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1999 |
NF-kappaB/Rel proteins are required for neuronal differentiation of SH-SY5Y neuroblastoma cells.
Topics: Cell Differentiation; Gene Expression Regulation; Humans; I-kappa B Kinase; Neuroblastoma; Neurons; NF-kappa B; Nuclear Proteins; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-rel; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1999 |
Modulation of carbachol-stimulated AP-1 DNA binding activity by therapeutic agents for bipolar disorder in human neuroblastoma SH-SY5Y cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Antipsychotic Agents; Bipolar Disorder; Calcium; Calcium Signaling; Carbachol; Carbamazepine; Chelating Agents; DNA; Dose-Response Relationship, Drug; Edetic Acid; Egtazic Acid; Gene Expression Regulation; Humans; Indoles; Ionomycin; Ionophores; Lithium; Muscarinic Agonists; Nerve Tissue Proteins; Neuroblastoma; Neurons; Phosphatidylinositols; Protein Binding; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Tumor Cells, Cultured; Valproic Acid | 1999 |
Attenuation of focal adhesion kinase signaling following depletion of agonist-sensitive pools of phosphatidylinositol 4,5-bisphosphate.
Topics: Androstadienes; Animals; Arsenicals; Cell Adhesion Molecules; Enzyme Inhibitors; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Lysophospholipids; Myosin-Light-Chain Kinase; Neuroblastoma; PC12 Cells; Phosphatidylinositol 3-Kinases; Phosphatidylinositol 4,5-Diphosphate; Phosphoinositide-3 Kinase Inhibitors; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rats; Receptors, Cholinergic; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Wortmannin | 1999 |
Induction of matrix metalloproteinase MMP-9 (92-kDa gelatinase) by retinoic acid in human neuroblastoma SKNBE cells: relevance to neuronal differentiation.
Topics: Cell Differentiation; Enzyme Induction; GAP-43 Protein; Humans; Immunohistochemistry; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neural Cell Adhesion Molecules; Neuroblastoma; Neurons; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2000 |
TPA induced expression and function of human connexin 26 by post-translational mechanisms in stably transfected neuroblastoma cells.
Topics: Animals; Connexin 26; Connexins; Gap Junctions; Gene Expression Regulation, Neoplastic; Humans; Mice; Neuroblastoma; Protein Processing, Post-Translational; RNA, Messenger; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1999 |
Activation and protein kinase C-dependent nuclear accumulation of ERK in differentiating human neuroblastoma cells.
Topics: Becaplermin; Cell Differentiation; Cell Nucleus; Enzyme Activation; Enzyme Inhibitors; Humans; Mitogen-Activated Protein Kinases; Nerve Growth Factor; Neuroblastoma; Phosphorylation; Platelet-Derived Growth Factor; Precipitin Tests; Protein Kinase C; Proto-Oncogene Proteins c-sis; Subcellular Fractions; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 2000 |
Role of Src kinases in the ADAM-mediated release of L1 adhesion molecule from human tumor cells.
Topics: Animals; Antigens, Surface; Breast Neoplasms; Cell Size; CHO Cells; Cricetinae; Disintegrins; Enzyme Inhibitors; Female; Flavonoids; Humans; Leukocyte L1 Antigen Complex; Membrane Glycoproteins; Metalloendopeptidases; Mice; Neural Cell Adhesion Molecules; Neuroblastoma; Phosphorylation; Protease Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fyn; Recombinant Proteins; Signal Transduction; src-Family Kinases; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured; Vanadates | 2000 |
A novel kinase, AATYK induces and promotes neuronal differentiation in a human neuroblastoma (SH-SY5Y) cell line.
Topics: Animals; Apoptosis Regulatory Proteins; Brain; Cell Differentiation; Cell Size; Cytoplasm; Enzyme Induction; Humans; Insulin-Like Growth Factor I; Mice; Neurites; Neuroblastoma; Neurons; Nuclear Envelope; Protein-Tyrosine Kinases; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Transfection; Tretinoin; Tumor Cells, Cultured | 2000 |
Retinoic acid negatively regulates neuropeptide Y expression in human neuroblastoma cells.
Topics: Blotting, Northern; Gene Expression Regulation, Neoplastic; Humans; Neuroblastoma; Neuropeptide Y; Protein Precursors; Protein Processing, Post-Translational; RNA, Messenger; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 2000 |
Beta-catenin expression in human neural cell lines following exposure to cytokines and growth factors.
Topics: Astrocytoma; beta Catenin; Brain Neoplasms; Bucladesine; Cadherins; Cell Differentiation; Cytokines; Cytoskeletal Proteins; Gene Expression Regulation, Neoplastic; Glioma; Growth Substances; HeLa Cells; HL-60 Cells; Humans; Neuroblastoma; Neurons; Retinal Neoplasms; Retinoblastoma; Tetradecanoylphorbol Acetate; Trans-Activators; Transcription, Genetic; Tumor Cells, Cultured | 2000 |
Phosphatidylcholine metabolism in nuclei of phorbol ester-activated LA-N-1 neuroblastoma cells.
Topics: Carbon Radioisotopes; Cell Nucleus; Choline; Choline Kinase; Cytidine Diphosphate Choline; Humans; Kinetics; Neuroblastoma; Palmitic Acid; Phosphatidylcholines; Phosphorylcholine; Tetradecanoylphorbol Acetate; Tritium; Tumor Cells, Cultured | 2000 |
Multi-hormonal regulation of IGFBP-6 expression in human neuroblastoma cells.
Topics: Antineoplastic Agents; Base Sequence; Blotting, Northern; Blotting, Western; Carcinogens; Cell Division; Chloramphenicol O-Acetyltransferase; Cholecalciferol; Cloning, Molecular; Down-Regulation; Humans; Insulin-Like Growth Factor Binding Protein 2; Insulin-Like Growth Factor Binding Protein 4; Insulin-Like Growth Factor Binding Protein 6; Isomerism; Luciferases; Models, Genetic; Molecular Sequence Data; Neuroblastoma; Plasmids; Promoter Regions, Genetic; RNA; Sequence Analysis, DNA; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tretinoin; Triiodothyronine; Tumor Cells, Cultured; Up-Regulation | 2000 |
Resistance to induced apoptosis in the human neuroblastoma cell line SK-N-SH in relation to neuronal differentiation. Role of Bcl-2 protein family.
Topics: Androstadienes; Apoptosis; Bacterial Proteins; Bacterial Toxins; bcl-X Protein; Biomarkers; Cell Differentiation; Cell Size; DNA Fragmentation; Gene Expression Regulation; Humans; Microtubule-Associated Proteins; Neuroblastoma; Neurons; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphopyruvate Hydratase; Protein Kinase C; Proto-Oncogene Proteins c-bcl-2; rhoA GTP-Binding Protein; Signal Transduction; Staurosporine; Synaptophysin; Tetradecanoylphorbol Acetate; Thapsigargin; Tretinoin; Tumor Cells, Cultured; Wortmannin | 2001 |
Activation of Ras, Raf-1 and protein kinase C in differentiating human neuroblastoma cells after treatment with phorbolester and NGF.
Topics: Blotting, Western; Carcinogens; Cell Differentiation; Enzyme Activation; Humans; Models, Genetic; Monomeric GTP-Binding Proteins; Myristic Acids; Nerve Growth Factor; Neuroblastoma; Phenotype; Phorbol Esters; Phosphorylation; Precipitin Tests; Protein Isoforms; Protein Kinase C; Protein Structure, Tertiary; Proto-Oncogene Proteins c-raf; ras Proteins; Signal Transduction; Subcellular Fractions; Tetradecanoylphorbol Acetate; Time Factors; Tissue Distribution; Tumor Cells, Cultured; Up-Regulation | 2001 |
A functional role for ERK in gene induction, but not in neurite outgrowth in differentiating neuroblastoma cells.
Topics: Calcium-Calmodulin-Dependent Protein Kinases; Cell Differentiation; DNA-Binding Proteins; Enzyme Activation; Enzyme Inhibitors; Flavonoids; GAP-43 Protein; Gene Expression; Humans; MAP Kinase Kinase Kinase 1; Mitogen-Activated Protein Kinases; Mitogens; Neurites; Neuroblastoma; Neuropeptide Y; Nuclear Proteins; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-fos; ras Proteins; Receptor, trkA; Serum Response Factor; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured | 2001 |
Up-regulation of cyclooxygenase-1 in neuroblastoma cell lines by retinoic acid and corticosteroids.
Topics: Adrenal Cortex Hormones; Aldosterone; Animals; Benzimidazoles; Bucladesine; Calcimycin; Cell Differentiation; Cycloheximide; Cyclooxygenase 1; Cyclooxygenase 2; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dexamethasone; Dinoprostone; Drug Synergism; Enzyme Induction; Estradiol; Gene Expression Regulation, Neoplastic; Genes, Reporter; Glioma; Hybrid Cells; Hydrocortisone; Ionophores; Isoenzymes; Luciferases; Membrane Proteins; Mice; Mifepristone; Neoplasm Proteins; Nerve Tissue Proteins; Neuroblastoma; Promoter Regions, Genetic; Prostaglandin-Endoperoxide Synthases; Protein Synthesis Inhibitors; Receptors, Glucocorticoid; Recombinant Fusion Proteins; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Transfection; Tretinoin; Tumor Cells, Cultured | 2001 |
RGS2: regulation of expression and nuclear localization.
Topics: Carbachol; Cell Differentiation; Cell Line; Cell Nucleus; Cholinergic Agonists; Colforsin; Culture Media; Cyclic AMP; Gene Expression Regulation; Green Fluorescent Proteins; Heat-Shock Response; Humans; Luminescent Proteins; Neuroblastoma; Neurons; Protein Kinase C; Recombinant Fusion Proteins; RGS Proteins; RNA, Messenger; Second Messenger Systems; Tetradecanoylphorbol Acetate; Transfection | 2001 |
Early c-Fos induction after cerebral ischemia: a possible neuroprotective role.
Topics: Animals; Blotting, Western; Chloramphenicol O-Acetyltransferase; Dopamine; Drug Synergism; Gene Expression Regulation; Glucose; Hippocampus; Humans; Immunohistochemistry; Ischemic Attack, Transient; Male; Neuroblastoma; Neurons; Neuroprotective Agents; Oxygen; Promoter Regions, Genetic; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Recombinant Fusion Proteins; Reperfusion Injury; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Tumor Cells, Cultured; Tyrosine 3-Monooxygenase | 2001 |
The Gem GTP-binding protein promotes morphological differentiation in neuroblastoma.
Topics: Animals; Carbachol; Cell Differentiation; Cholinergic Agonists; Ganglioneuroblastoma; Humans; Immediate-Early Proteins; Melanoma; Mice; Monomeric GTP-Binding Proteins; Neoplasm Proteins; Neuroblastoma; Receptors, Muscarinic; Tetradecanoylphorbol Acetate; Trigeminal Ganglion; Tumor Cells, Cultured | 2001 |
Down-regulation of growth factor-stimulated MAP kinase signaling in cytotoxic drug-resistant human neuroblastoma cells.
Topics: Active Transport, Cell Nucleus; Adenosine; Antineoplastic Agents; Cell Nucleus; Down-Regulation; Doxorubicin; Drug Resistance, Neoplasm; Epidermal Growth Factor; ErbB Receptors; Growth Substances; Humans; Lysophospholipids; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Models, Biological; Neuroblastoma; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2001 |
Interferon-gamma cooperates with retinoic acid and phorbol ester to induce differentiation and growth inhibition of human neuroblastoma cells.
Topics: Cell Differentiation; Drug Synergism; Genes, myc; Humans; Interferon-gamma; Neuroblastoma; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 2001 |
A PKCbeta isoform mediates phorbol ester-induced activation of Erk1/2 and expression of neuronal differentiation genes in neuroblastoma cells.
Topics: Cell Differentiation; Culture Media, Serum-Free; Enzyme Inhibitors; Flavonoids; GAP-43 Protein; Gene Expression Regulation; Genes, Reporter; Isoenzymes; Mesylates; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neurites; Neuroblastoma; Neurons; Neuropeptide Y; Phosphorylation; Promoter Regions, Genetic; Protein Kinase C; Protein Kinase C beta; Pyrroles; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2001 |
Tumor promoters inhibit morphological differentiation in cultured mouse neuroblastoma cells.
Topics: Bromodeoxyuridine; Cell Differentiation; Cell Line; Diterpenes; Dose-Response Relationship, Drug; Neuroblastoma; Neurons; Papaverine; Phorbols; Prostaglandins E; Tetradecanoylphorbol Acetate | 1978 |
Detection of multiple hormones and their mRNAs in human neuroblastoma cell line NB-1 using in situ hybridization, immunocytochemistry and radioimmunoassay.
Topics: Bucladesine; Cytoplasmic Granules; Enkephalin, Methionine; Hormones; Humans; Immunohistochemistry; In Situ Hybridization; Microscopy, Electron; Neuroblastoma; Neuropeptide Y; Peptide PHI; Protein Precursors; Radioimmunoassay; RNA, Messenger; Substance P; Tachykinins; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine 3-Monooxygenase; Vasoactive Intestinal Peptide | 1992 |
The epithelial phenotype of human neuroblastoma cells express bradykinin, endothelin, and angiotensin II receptors that stimulate phosphoinositide hydrolysis.
Topics: Angiotensin II; Bradykinin; Endothelins; Epithelium; Humans; Hydrolysis; Neuroblastoma; Pertussis Toxin; Phosphatidylinositols; Receptors, Angiotensin; Receptors, Bradykinin; Receptors, Cell Surface; Receptors, Endothelin; Receptors, Neurotransmitter; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1992 |
Suppressive effect of carbachol on forskolin-stimulated neurite outgrowth in human neuroblastoma NB-OK1 cells.
Topics: Atropine; Calcium; Calcium Channel Blockers; Carbachol; Cell Line; Colforsin; Cyclic AMP; Drug Interactions; Egtazic Acid; Gallic Acid; Humans; Inositol; Inositol Phosphates; Kinetics; Neurites; Neuroblastoma; Tetradecanoylphorbol Acetate; Vasoactive Intestinal Peptide | 1992 |
Intracellular delivery of protein kinase C-alpha or -epsilon isoform-specific antibodies promotes acquisition of a morphologically differentiated phenotype in neuroblastoma cells.
Topics: Cell Differentiation; Down-Regulation; Isoenzymes; Neuroblastoma; Phosphatidylinositols; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Distinct regulation of vasoactive intestinal peptide (VIP) expression at mRNA and peptide levels in human neuroblastoma cells.
Topics: Bucladesine; Carbachol; Humans; Neuroblastoma; Peptide Biosynthesis; Radioimmunoassay; RNA, Messenger; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured; Vasoactive Intestinal Peptide | 1992 |
Discordant estimates of heterologous promoter activity as determined by reporter gene mRNA levels and enzyme activity.
Topics: Base Sequence; beta-Galactosidase; Chloramphenicol O-Acetyltransferase; Cloning, Molecular; Cytomegalovirus; Genes, Bacterial; Humans; Kinetics; Molecular Sequence Data; Neuroblastoma; Oligodeoxyribonucleotides; Plasmids; Polymerase Chain Reaction; Promoter Regions, Genetic; Recombinant Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Transfection; Tumor Cells, Cultured | 1992 |
A combined evaluation of biochemical and morphological changes during human neuroblastoma cell differentiation.
Topics: Biomarkers, Tumor; Catecholamines; Cell Differentiation; Cytarabine; Gene Expression Regulation, Neoplastic; Humans; Interferon-gamma; Neoplasm Proteins; Nerve Growth Factors; Nerve Tissue Proteins; Neuroblastoma; Neuropeptides; Neurotransmitter Agents; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1992 |
Transcriptional regulation of neuromodulin (GAP-43) in mouse neuroblastoma clone N1E-115 as evaluated by the RT/PCR method.
Topics: Animals; Base Sequence; Calmodulin-Binding Proteins; Cell Line; DNA; DNA, Neoplasm; GAP-43 Protein; Gene Expression Regulation, Neoplastic; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Membrane Glycoproteins; Mice; Molecular Sequence Data; Nerve Tissue Proteins; Neuroblastoma; Oligodeoxyribonucleotides; Polymerase Chain Reaction; Rats; RNA-Directed DNA Polymerase; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1992 |
Activation of protein kinase C in permeabilized human neuroblastoma SH-SY5Y cells.
Topics: Acetophenones; Amino Acid Sequence; Arachidonic Acids; Calcium; Cell Membrane; Cell Membrane Permeability; Digitonin; Diglycerides; Dose-Response Relationship, Drug; Enzyme Activation; Humans; Molecular Sequence Data; Myelin Basic Protein; Neuroblastoma; Phospholipases A; Phospholipases A2; Phosphorus; Phosphorus Radioisotopes; Phosphorylation; Protein Kinase C; Quinacrine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
A complex consisting of pp60c-src/pp60c-srcN and a 38 kDa protein is highly enriched in growth cones from differentiated SH-SY5Y neuroblastoma cells.
Topics: Cell Differentiation; Cell Fractionation; Humans; Microscopy, Electron; Molecular Weight; Neuroblastoma; Neurons; Phosphoproteins; Proto-Oncogene Mas; Proto-Oncogene Proteins pp60(c-src); Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Evidence for a novel mechanism of activation of phospholipase D by endothelin-1 in neuroblastoma cells.
Topics: Animals; Calcimycin; Endothelins; Enzyme Activation; Indoles; Kinetics; Neuroblastoma; Phospholipase D; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Regulation of neurite outgrowth through protein kinase C and protease nexin-1 in neuroblastoma cell.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Base Sequence; Cycloheximide; Dactinomycin; Humans; Isoquinolines; Molecular Sequence Data; Neurites; Neuroblastoma; Neurofilament Proteins; Piperazines; Protein Kinase Inhibitors; Protein Kinases; Rats; RNA, Messenger; RNA, Neoplasm; Serum Albumin, Bovine; Tetradecanoylphorbol Acetate; Thrombin; Tumor Cells, Cultured | 1992 |
Platelet-derived growth factor potentiates phorbol ester-induced neuronal differentiation of human neuroblastoma cells.
Topics: Cell Differentiation; DNA Replication; DNA, Neoplasm; Drug Synergism; Humans; Neoplasm Proteins; Nerve Tissue Proteins; Neuroblastoma; Neurons; Platelet-Derived Growth Factor; Receptors, Platelet-Derived Growth Factor; Recombinant Proteins; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Protein kinase C remains functionally active during TPA induced neuronal differentiation of SH-SY5Y human neuroblastoma cells.
Topics: Blotting, Northern; Cell Differentiation; Cell Membrane; Cytosol; Humans; Neuroblastoma; Neurons; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Dioctanoylglycerol stimulates accumulation of [methyl-14C]choline and its incorporation into acetylcholine and phosphatidylcholine in a human cholinergic neuroblastoma cell line.
Topics: Acetylcholine; Choline; Diglycerides; Humans; Nervous System Neoplasms; Neuroblastoma; Osmolar Concentration; Parasympathetic Nervous System; Phosphatidylcholines; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Reversible structural alterations of undifferentiated and differentiated human neuroblastoma cells induced by phorbol ester.
Topics: Actins; Cell Differentiation; Cytoskeleton; Humans; In Vitro Techniques; Neurites; Neuroblastoma; Neurons; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Distinct mechanisms of differentiation of SH-SY5Y neuroblastoma cells by protein kinase C activators and inhibitors.
Topics: Alkaloids; Cell Differentiation; Diglycerides; Enzyme Activation; Enzyme Inhibitors; Humans; Neuroblastoma; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
The effect of protein kinase C activation on muscarinic-M3- and K(+)-evoked release of [3H]noradrenaline and increases in intracellular Ca2+ in human neuroblastoma SH-SY5Y cells.
Topics: Calcium; Choline; Enzyme Activation; Humans; Intracellular Fluid; Neuroblastoma; Norepinephrine; Potassium; Protein Kinase C; Receptors, Muscarinic; Tetradecanoylphorbol Acetate; Tritium; Tumor Cells, Cultured | 1992 |
Multiple neurite formation in neuroblastoma cell lines by griseolic acid, a potent inhibitor of cyclic nucleotide phosphodiesterases.
Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Animals; Axons; Bucladesine; Butyrates; Butyric Acid; Cell Differentiation; Cell Line; Cyclic AMP; DNA Replication; Neuroblastoma; Tetradecanoylphorbol Acetate; Tretinoin | 1991 |
Effects of second messenger system activation on functional expression of tyrosine hydroxylase fusion gene constructs in neuronal and nonneuronal cells.
Topics: Animals; Base Sequence; Blotting, Northern; Cells, Cultured; Chlorocebus aethiops; Colforsin; Cyclic AMP; Dexamethasone; Enzyme Induction; Fibroblasts; Glioma; HeLa Cells; Humans; Mice; Molecular Sequence Data; Neuroblastoma; Neurons; Organ Specificity; Promoter Regions, Genetic; Rats; Recombinant Fusion Proteins; Regulatory Sequences, Nucleic Acid; RNA, Messenger; Second Messenger Systems; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Tumor Cells, Cultured; Tyrosine 3-Monooxygenase | 1991 |
Inhibition of protein kinase C induces differentiation in Neuro-2a cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetylcholinesterase; Animals; Cell Differentiation; Cell Division; DNA; Isoquinolines; Mice; Microtubule-Associated Proteins; Nerve Tissue Proteins; Neuroblastoma; Piperazines; Protein Kinase C; RNA; Tetradecanoylphorbol Acetate; Time Factors; Tubulin; Tumor Cells, Cultured | 1990 |
In vitro modulation and relationship between N-myc and HLA class I RNA steady-state levels in human neuroblastoma cells.
Topics: Blotting, Northern; Bucladesine; Epidermal Growth Factor; Gene Amplification; Gene Expression Regulation, Neoplastic; Genes, myc; Histocompatibility Antigens Class I; Humans; In Vitro Techniques; Interferon-gamma; Nerve Growth Factors; Neuroblastoma; Oncogene Protein p55(v-myc); RNA; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1990 |
Phorbol 12-myristate-13-acetate (PMA) stimulates a differential expression of cholecystokinin (CCK) and c-fos mRNA in a human neuroblastoma cell line.
Topics: 1-Methyl-3-isobutylxanthine; Base Sequence; Cell Line; Cholecystokinin; Gene Expression Regulation, Neoplastic; Humans; Molecular Sequence Data; Neuroblastoma; Protein Kinase C; Proto-Oncogene Mas; Proto-Oncogene Proteins c-fos; RNA, Messenger; Tetradecanoylphorbol Acetate | 1991 |
The effect of calcium channel antagonists on the release of [3H]noradrenaline in the human neuroblastoma, SH-SY5Y.
Topics: Calcium Channel Blockers; Carbachol; Cations, Divalent; Cell Line; Humans; Nervous System Neoplasms; Neuroblastoma; Norepinephrine; Potassium; Tetradecanoylphorbol Acetate | 1991 |
Endothelin and calcium signaling in NG108-15 neuroblastoma x glioma cells.
Topics: Animals; Calcium; Cell Differentiation; Endothelins; Ethanol; Glioma; Mice; Neuroblastoma; Potassium Chloride; Protein Kinase C; Temperature; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
N-myc disrupts protein kinase C-mediated signal transduction in neuroblastoma.
Topics: Cytosol; Gene Expression Regulation, Neoplastic; Humans; Neuroblastoma; NF-kappa B; Promoter Regions, Genetic; Protein Kinase C; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-myc; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1991 |
Modulation of neurite outgrowth in neuroblastoma cells by protein kinase C and platelet-activating factor.
Topics: Animals; Cell Division; Humans; Mice; Neurites; Neuroblastoma; Platelet Activating Factor; Protein Kinase C; Tetradecanoylphorbol Acetate; Thrombin; Tumor Cells, Cultured | 1991 |
Insulin-like growth factor I shifts from promoting cell division to potentiating maturation during neuronal differentiation.
Topics: Blotting, Northern; Blotting, Western; Cell Differentiation; Cell Division; Cell Line; Drug Synergism; Gene Expression; Genes, myc; Humans; Insulin; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Kinetics; Neuroblastoma; Neurons; Neuropeptide Y; RNA, Neoplasm; Tetradecanoylphorbol Acetate | 1991 |
Second messenger-induced modulation of Thy-1 antigen expression: an ELISA study using murine thymic and neuroblastoma cells.
Topics: Animals; Antigens, Surface; Bucladesine; Down-Regulation; Enzyme-Linked Immunosorbent Assay; In Vitro Techniques; Mice; Mice, Inbred CBA; Neuroblastoma; Second Messenger Systems; Tetradecanoylphorbol Acetate; Thy-1 Antigens; Thymus Gland | 1990 |
Stimulation of phospholipase D activity in human neuroblastoma (LA-N-2) cells by activation of muscarinic acetylcholine receptors or by phorbol esters: relationship to phosphoinositide turnover.
Topics: Alkaloids; Carbachol; Glycerophospholipids; Humans; Inositol Phosphates; Neuroblastoma; Phosphatidic Acids; Phospholipase D; Receptors, Muscarinic; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
Expression of a chimeric VIP gene is targeted to the intestine in transgenic mice.
Topics: Animals; Base Sequence; Chimera; Chloramphenicol O-Acetyltransferase; Colforsin; Gene Expression; Gene Expression Regulation, Neoplastic; Humans; Intestinal Mucosa; Luciferases; Mice; Mice, Transgenic; Molecular Sequence Data; Neuroblastoma; Tetradecanoylphorbol Acetate; Vasoactive Intestinal Peptide | 1990 |
Possible involvement of calpain in down-regulation of protein kinase C.
Topics: Amino Acid Sequence; Calpain; Enzyme Activation; Humans; Molecular Sequence Data; Neoplasm Proteins; Neuroblastoma; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Reduction of muscarinic receptor density and of guanine nucleotide-stimulated phosphoinositide hydrolysis in human SH-SY5Y neuroblastoma cells following long-term treatment with 12-O-tetradecanoylphorbol 13-acetate or mezerein.
Topics: Calcium; Culture Media; Cytoplasm; Diterpenes; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Hydrolysis; Inositol Phosphates; Neuroblastoma; Osmolar Concentration; Phosphatidylinositols; Protein Kinase C; Receptors, Muscarinic; Sodium Fluoride; Terpenes; Tetradecanoylphorbol Acetate; Thionucleotides; Time Factors; Tumor Cells, Cultured | 1990 |
Protein kinase C is involved in desensitization of muscarinic receptors induced by phorbol esters but not by receptor agonists.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcimycin; Carbachol; Cyclic GMP; Down-Regulation; Isoquinolines; Mice; N-Methylscopolamine; Neuroblastoma; Parasympathomimetics; Phorbol 12,13-Dibutyrate; Phorbol Esters; Piperazines; Protein Kinase C; Receptors, Muscarinic; Scopolamine Derivatives; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Attenuation of opioid receptor activity by phorbol esters in neuroblastoma x glioma NG108-15 hybrid cells.
Topics: Adenosine Diphosphate Ribose; Cyclic AMP; Glioma; GTP Phosphohydrolases; GTP-Binding Proteins; Hybrid Cells; Neuroblastoma; Receptors, Adrenergic, alpha; Receptors, Muscarinic; Receptors, Opioid; Tetradecanoylphorbol Acetate | 1990 |
Tetanus toxin attenuates the ability of phorbol myristate acetate to mobilize cytosolic protein kinase C in NG-108 cells.
Topics: Acetylcholine; Alprostadil; Atrial Natriuretic Factor; Cyclic AMP; Cyclic GMP; Cytosol; Neuroblastoma; Protein Kinase C; Tetanus Toxin; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Mitogenically uncoupled insulin and IGF-I receptors of differentiated human neuroblastoma cells are functional and mediate ligand-induced signals.
Topics: Actins; Cell Differentiation; Humans; Insulin; Insulin-Like Growth Factor I; Mitosis; Neuroblastoma; Ornithine Decarboxylase; Phosphorylation; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-myc; Receptor, Insulin; Receptors, Cell Surface; Receptors, Somatomedin; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Desensitization of muscarinic M1 receptors of murine neuroblastoma cells (clone N1E-115) without receptor down-regulation and protein kinase C activity.
Topics: Animals; Carbachol; Down-Regulation; Guanosine Monophosphate; Inositol Phosphates; Mice; N-Methylscopolamine; Neuroblastoma; Parasympatholytics; Protein Kinase C; Receptors, Muscarinic; Scopolamine Derivatives; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
N-myc gene amplification in neuroblastoma is associated with altered phosphorylation of a proliferation related polypeptide (Op18).
Topics: Cell Division; Chromosomes, Human, Pair 1; Electrophoresis, Gel, Two-Dimensional; Gene Amplification; Genes, myc; Humans; Microtubule Proteins; Neoplasm Proteins; Neuroblastoma; Phosphoproteins; Phosphorylation; Proto-Oncogene Proteins c-myc; Stathmin; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Protein kinase C and its 80-kilodalton substrate protein in neuroblastoma cell neurite outgrowth.
Topics: Axons; Calcium; Cell Line; Humans; Neoplasm Proteins; Nerve Growth Factors; Nerve Tissue Proteins; Neuroblastoma; Phosphorylation; Protein Kinase C; Substrate Specificity; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1990 |
12-O-tetradecanoylphorbol 13-acetate and forskolin modify muscarinic receptor-linked Ca2+ mobilization in SH-SY5Y neuroblastoma cells through different mechanisms.
Topics: Benzofurans; Binding, Competitive; Biomechanical Phenomena; Calcium; Carbachol; Colforsin; Cytosol; Fluorescent Dyes; Fura-2; Ionomycin; Membrane Potentials; N-Methylscopolamine; Neuroblastoma; Osmolar Concentration; Receptors, Muscarinic; Scopolamine Derivatives; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Effects of bryostatins 1 and 2 on morphological and functional differentiation of SH-SY5Y human neuroblastoma cells.
Topics: Antineoplastic Agents; Bryostatins; DNA, Neoplasm; Down-Regulation; Enzyme Induction; Humans; Lactones; Macrolides; Neuroblastoma; Norepinephrine; Oncogenes; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptors, Muscarinic; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Muscarinic receptor-mediated translocation of calmodulin in SK-N-SH human neuroblastoma cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenylyl Cyclases; Biological Transport; Calcium; Calmodulin; Carbachol; Humans; Ionomycin; Isoquinolines; Kinetics; Neuroblastoma; Piperazines; Receptors, Muscarinic; Tetradecanoylphorbol Acetate | 1990 |
Divergent changes of chromogranin A/secretogranin II levels in differentiating human neuroblastoma cells.
Topics: Cell Differentiation; Cell Line; Chromogranin A; Chromogranins; Humans; Nerve Tissue Proteins; Neuroblastoma; Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
1-Oleoyl-2-acetyl-glycerol and phorbol diester stimulate Ca2+ influx through Ca2+ channels in neuroblastoma x glioma hybrid NG108-15 cells.
Topics: Calcium; Diglycerides; Glioma; Glycerides; Humans; Hybrid Cells; Ion Channels; Kinetics; Nervous System Neoplasms; Neuroblastoma; Tetradecanoylphorbol Acetate | 1986 |
Single transient potassium channels in human neuroblastoma cells induced to differentiate in vitro.
Topics: Cell Differentiation; Humans; Ion Channels; Membrane Potentials; Neuroblastoma; Potassium; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1988 |
Rapid dephosphorylation of protein kinase C substrates by protein kinase A activators results from inhibition of diacylglycerol release.
Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Animals; Arachidonic Acid; Arachidonic Acids; Biological Transport; Bradykinin; Brain; Bucladesine; Colforsin; Cricetinae; Diglycerides; Enzyme Activation; Glycerides; Hybrid Cells; Inositol Phosphates; Kinetics; Mice; Molecular Weight; Neuroblastoma; Phosphates; Phosphatidylinositols; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein Kinases; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
Induction of morphological differentiation of human neuroblastoma cells is accompanied by induction of tissue-type plasminogen activator.
Topics: Cell Differentiation; Cell Line; Gene Expression Regulation; Humans; Molecular Weight; Nerve Growth Factors; Neuroblastoma; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Tissue Plasminogen Activator; Tumor Cells, Cultured | 1989 |
Alterations in plasminogen activator and inhibitor activity during the differentiation of a human neuroblastoma cell line, SMS-KAN.
Topics: Bromodeoxyuridine; Bucladesine; Butyrates; Butyric Acid; Cell Differentiation; Cell Line; DNA Replication; Fibrinolysis; Glycoproteins; Humans; Neuroblastoma; Plasminogen Activators; Plasminogen Inactivators; Tetradecanoylphorbol Acetate; Tretinoin | 1989 |
Effects of toxin II from the scorpion Androctonus australis Hector on sodium current in neuroblastoma cells and their modulation by oleic acid.
Topics: Animals; In Vitro Techniques; Membrane Lipids; Neuroblastoma; Neurons; Oleic Acid; Oleic Acids; Scorpion Venoms; Sodium; Sodium Channels; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
Expression of calmodulin-dependent phosphodiesterase, calmodulin-dependent protein phosphatase, and other calmodulin-binding proteins in human SMS-KCNR neuroblastoma cells.
Topics: Avidin; Calcineurin; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Calmodulin-Binding Proteins; Cell Differentiation; Electrophoresis, Polyacrylamide Gel; Humans; Immunoblotting; Neuroblastoma; Phosphoprotein Phosphatases; Phosphoric Diester Hydrolases; Phosphorylation; Protein Kinases; Synaptosomes; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1989 |
Human neuroblastoma cells acquire regulated secretory properties and different sensitivity to Ca2+ and alpha-latrotoxin after exposure to differentiating agents.
Topics: Biological Transport; Bromodeoxyuridine; Bucladesine; Calcium; Cell Compartmentation; Cell Differentiation; Cell Survival; Chromaffin Granules; Dopamine; Ethers; Humans; Ionomycin; Kinetics; Neuroblastoma; Protein Kinase C; Spider Venoms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
Protein kinase C activation and down-regulation in relation to phorbol ester-induced differentiation of SH-SY5Y human neuroblastoma cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Calcium; Calcium Channels; Cell Compartmentation; Cell Differentiation; Diglycerides; Enzyme Activation; Humans; Isoquinolines; Membrane Potentials; Neuroblastoma; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Receptors, Muscarinic; Sulfonamides; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured | 1989 |
Changes in expression of tyrosine hydroxylase immunoreactivity in human SMS-KCNR neuroblastoma following retinoic acid or phorbol ester-induced differentiation.
Topics: Cell Differentiation; Cell Line; Cells, Cultured; Humans; Neuroblastoma; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured; Tyrosine 3-Monooxygenase | 1989 |
12-O-tetradecanoyl-phorbol-13-acetate-induced differentiation of human neuroblastoma cells is not accompanied by an increase in the intracellular concentration of cyclic AMP.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Carrier Proteins; Clone Cells; Colchicine; Cyclic AMP; Mice; Neoplasms, Experimental; Neuroblastoma; Phorbols; Protein Binding; Tetradecanoylphorbol Acetate | 1985 |
Cell type-specific control of human neuronectin secretion by polypeptide mediators and phorbol ester.
Topics: Antibodies, Monoclonal; Extracellular Matrix; Extracellular Matrix Proteins; Fibroblast Growth Factors; Fibroblasts; Glioma; Growth Substances; Humans; Immunologic Techniques; In Vitro Techniques; Nerve Growth Factors; Nerve Tissue Proteins; Neuroblastoma; Neuroectodermal Tumors, Primitive, Peripheral; Sarcoma, Ewing; Secretory Rate; Tetradecanoylphorbol Acetate; Transforming Growth Factors; Tumor Necrosis Factor-alpha | 1989 |
Uptake of exogenous phosphatidylserine by human neuroblastoma cells stimulates the incorporation of [methyl-14C]choline into phosphatidylcholine.
Topics: Biological Transport; Choline; Enzyme Activation; Humans; Neuroblastoma; Phosphatidylcholines; Phosphatidylserines; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
(-)-Indolactam V activates protein kinase C and induces changes in muscarinic receptor functions in SH-SY5Y human neuroblastoma cells.
Topics: Calcium; Cell Compartmentation; Cell Differentiation; Cell Membrane; Enzyme Activation; Humans; Indoles; Lactams; Neuroblastoma; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptors, Muscarinic; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
TPA-induced neurite formation in a neuroblastoma cell line (SH-SY5Y) is associated with increased IGF-I receptor mRNA and binding.
Topics: Binding, Competitive; Cell Differentiation; Dendrites; Insulin-Like Growth Factor I; Neuroblastoma; RNA, Messenger; Somatomedins; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
Alteration in the regulation of neuronal muscarinic acetylcholine receptor number induced by chronic lithium in neuroblastoma cells.
Topics: Animals; Calcimycin; Carbachol; Cell Line; Cell Membrane; Chlorides; Kinetics; Lithium; Lithium Chloride; Mice; Neuroblastoma; Neurons; Receptors, Muscarinic; Tetradecanoylphorbol Acetate | 1988 |
Bradykinin-induced generation of inositol 1,4,5-trisphosphate in fibroblasts and neuroblastoma cells: effect of pertussis toxin, extracellular calcium, and down-regulation of protein kinase C.
Topics: Adenosine Diphosphate Ribose; Bradykinin; Calcium; Enzyme Activation; Fibroblasts; Glioma; GTP-Binding Proteins; Hybrid Cells; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Neuroblastoma; Pertussis Toxin; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoinositide Phospholipase C; Phosphoric Diester Hydrolases; Protein Kinase C; Sugar Phosphates; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1988 |
Phorbol ester inhibits bradykinin-stimulated inositol trisphosphate formation and calcium mobilization in neuroblastoma x glioma hybrid NG108-15 cells.
Topics: Bradykinin; Calcium; Cell Line; Diglycerides; Glioma; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Neuroblastoma; Protein Kinase C; Receptors, Bradykinin; Receptors, Neurotransmitter; Sugar Phosphates; Tetradecanoylphorbol Acetate; Thionucleotides; Type C Phospholipases | 1987 |
Differentiation of human neuroblastoma cells: marked potentiation of prostaglandin E-stimulated accumulation of cyclic AMP by retinoic acid.
Topics: Adenylyl Cyclases; Alprostadil; Bucladesine; Cell Differentiation; Cyclic AMP; Dinoprostone; Drug Synergism; Humans; Indomethacin; Nerve Growth Factors; Neuroblastoma; Prostaglandins E; Receptors, Prostaglandin; Receptors, Prostaglandin E; Tachyphylaxis; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1988 |
Phosphatidylethanol biosynthesis in ethanol-exposed NG108-15 neuroblastoma X glioma hybrid cells. Evidence for activation of a phospholipase D phosphatidyl transferase activity by protein kinase C.
Topics: Animals; Cell Line; Enzyme Activation; Ethanol; Glioma; Glycerophospholipids; Hybrid Cells; Kinetics; Neuroblastoma; Phosphatidic Acids; Phospholipase D; Phospholipases; Protein Kinase C; Tetradecanoylphorbol Acetate | 1989 |
Alterations of phospholipid metabolism by phorbol esters and fatty acids occur by different intracellular mechanisms in cultured glioma, neuroblastoma, and hybrid cells.
Topics: Animals; Cell Line; Choline; Ethanolamine; Ethanolamines; Fatty Acids; Glioma; Hybrid Cells; Kinetics; Neuroblastoma; Phosphatidylcholines; Phospholipids; Subcellular Fractions; Tetradecanoylphorbol Acetate | 1989 |
Differential effects of the tumor promoter phorbol-12-myristate-13-acetate on the morphological and biochemical differentiation of N-18 mouse neuroblastoma cells.
Topics: Acetylcholinesterase; Animals; Axons; Bucladesine; Carrier Proteins; Cell Transformation, Neoplastic; Cells, Cultured; Cyclic AMP Receptor Protein; Fetal Blood; Growth Inhibitors; Mice; Neuroblastoma; Phorbols; Tetradecanoylphorbol Acetate | 1985 |
Mitogenic response of human SH-SY5Y neuroblastoma cells to insulin-like growth factor I and II is dependent on the stage of differentiation.
Topics: Cell Cycle; Cell Differentiation; Cell Line; DNA; Humans; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Neuroblastoma; Ornithine Decarboxylase; Receptors, Cell Surface; Receptors, Somatomedin; Somatomedins; Tetradecanoylphorbol Acetate | 1986 |
Carbachol-induced accumulation of inositol-1-phosphate in neurohybridoma NCB-20 cells: effects of lithium and phorbol esters.
Topics: Animals; Atropine; Benzodiazepinones; Brain; Carbachol; Cell Line; Chlorides; Cricetinae; Cricetulus; Embryo, Mammalian; Hybridomas; Inositol Phosphates; Lithium; Lithium Chloride; Mice; Neuroblastoma; Phorbol 12,13-Dibutyrate; Phorbol Esters; Pirenzepine; Sugar Phosphates; Tetradecanoylphorbol Acetate | 1986 |
The protein kinase C activator, 12-O-tetradecanoylphorbol-13-acetate (TPA), inhibits muscarinic (M1) receptor-mediated inositol phosphate release and cyclic GMP formation in murine neuroblastoma cells (clone N1E-115).
Topics: Animals; Carbachol; Cell Line; Cyclic GMP; Inositol Phosphates; Mice; Neuroblastoma; Phorbol Esters; Phorbols; Protein Kinase C; Receptors, Muscarinic; Sugar Phosphates; Tetradecanoylphorbol Acetate | 1986 |
Phorbol esters alter muscarinic receptor binding and inhibit polyphosphoinositide breakdown in human neuroblastoma (SH-SY5Y) cells.
Topics: Atropine; Cell Line; Humans; Neuroblastoma; Phorbol Esters; Phosphatidylinositols; Protein Kinase C; Receptors, Muscarinic; Tetradecanoylphorbol Acetate | 1986 |
Phorbol ester-induced inhibition of cyclic GMP formation mediated by muscarinic receptors in murine neuroblastoma cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcimycin; Carbachol; Cell Line; Cyclic GMP; Dose-Response Relationship, Drug; Histamine; Isoquinolines; Mice; Neuroblastoma; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Piperazines; Receptors, Muscarinic; Tetradecanoylphorbol Acetate | 1987 |
Inhibition of receptor-mediated stimulation of cyclic AMP accumulation in neuroblastoma-hybrid NCB-20 cells by a phorbol ester.
Topics: Adenylyl Cyclases; Animals; Cell Line; Colforsin; Cricetinae; Cyclic AMP; Dinoprostone; Dopamine; GTP-Binding Proteins; Hybrid Cells; Mice; Neuroblastoma; Phosphorylation; Prostaglandins E; Protein Kinase C; Receptors, Cell Surface; Tetradecanoylphorbol Acetate | 1987 |
Bradykinin-activated transmembrane signals are coupled via No or Ni to production of inositol 1,4,5-trisphosphate, a second messenger in NG108-15 neuroblastoma-glioma hybrid cells.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Bradykinin; Calcium; Cell Line; Diglycerides; Glioma; GTP-Binding Proteins; Humans; Hybrid Cells; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Membrane Potentials; Neuroblastoma; Pertussis Toxin; Sugar Phosphates; Tetradecanoylphorbol Acetate; Tetraethylammonium; Tetraethylammonium Compounds; Virulence Factors, Bordetella | 1986 |
Activation of protein kinase C induces rapid internalization and subsequent degradation of muscarinic acetylcholine receptors in neuroblastoma cells.
Topics: Animals; Calcimycin; Calcium; Carbachol; Cell Line; Diglycerides; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Activation; Kinetics; Mice; Neuroblastoma; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphatidylserines; Protein Kinase C; Quinuclidinyl Benzilate; Receptors, Cholinergic; Tetradecanoylphorbol Acetate; Time Factors | 1986 |
Development of a neural phenotype in differentiating ganglion cell-derived human neuroblastoma cells.
Topics: Acetylcholine; Atropine; Calcimycin; Calcium; Cell Differentiation; Clone Cells; Ganglia, Sympathetic; Humans; Membrane Potentials; Muscarine; Neuroblastoma; Norepinephrine; Phenotype; Potassium; Receptors, Muscarinic; Rubidium; Tetradecanoylphorbol Acetate | 1986 |
Decline in c-myc mRNA expression but not the induction of c-fos mRNA expression is associated with differentiation of SH-SY5Y human neuroblastoma cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Cell Differentiation; Cell Line; Diglycerides; Gene Expression Regulation; Humans; Isoquinolines; Neuroblastoma; Oncogenes; Piperazines; Protein Kinase C; RNA, Messenger; Tetradecanoylphorbol Acetate | 1988 |
Lineage-specific regulation of the vasoactive intestinal peptide gene in neuroblastoma cells is conferred by 5.2 kilobases of 5'-flanking sequence.
Topics: Base Sequence; Cell Line; Chromosome Deletion; Colforsin; Enhancer Elements, Genetic; Humans; Molecular Sequence Data; Molecular Weight; Neuroblastoma; Plasmids; Tetradecanoylphorbol Acetate; Transfection; Vasoactive Intestinal Peptide | 1988 |
Different regulation of N- and c-myc expression during phorbol ester-induced maturation of human SH-SY5Y neuroblastoma cells.
Topics: Cell Cycle; Cell Differentiation; Gene Expression Regulation; Neuroblastoma; Proto-Oncogene Proteins; Proto-Oncogenes; Tetradecanoylphorbol Acetate; Tretinoin | 1987 |
Growth of tumor colonies mediated by phorbol ester and 13-cis retinoic acid in mixed cultures.
Topics: Animals; Cell Communication; Cell Differentiation; Cell Division; Cell Line; Fibroblasts; Glioma; Neuroblastoma; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1987 |
Quantitation of protein kinase C by immunoblot--expression in different cell lines and response to phorbol esters.
Topics: Animals; Antigen-Antibody Complex; Cattle; Cell Line; Glioma; Humans; Immunologic Techniques; Mice; Neuroblastoma; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Rabbits; Rats; Tetradecanoylphorbol Acetate | 1987 |
Muscarinic receptors in human SH-SY5Y neuroblastoma cell line: regulation by phorbol ester and retinoic acid-induced differentiation.
Topics: Acetylcholinesterase; Atropine; Binding, Competitive; Cell Differentiation; Cell Line; Choline O-Acetyltransferase; Humans; Neuroblastoma; Pirenzepine; Quinuclidinyl Benzilate; Receptors, Muscarinic; Tetradecanoylphorbol Acetate; Tretinoin | 1987 |
Human melanoma proteoglycan: expression in hybrids controlled by intrinsic and extrinsic signals.
Topics: Aggrecans; Animals; Antibodies, Monoclonal; Cell Line; Cholera Toxin; Chromosome Mapping; Chromosomes, Human, 13-15; Cricetinae; Cricetulus; Extracellular Matrix Proteins; Gene Expression Regulation; Glycoproteins; Humans; Hybrid Cells; Lectins, C-Type; Lymphocytes; Melanocytes; Melanoma; Mice; Neoplasm Proteins; Neuroblastoma; Proteoglycans; Rats; Tetradecanoylphorbol Acetate | 1986 |
Differential regulation of phosphatidylcholine biosynthesis by 12-O-tetradecanoylphorbol-13-acetate and diacylglycerol in NG108-15 neuroblastoma x glioma hybrid cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Choline; Chromatography, High Pressure Liquid; Diglycerides; Glioma; Glycerides; Hybrid Cells; Isoquinolines; Neuroblastoma; Phosphatidylcholines; Piperazines; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1987 |
Phosphatidylcholine biosynthesis in the neuroblastoma-glioma hybrid cell line NG108-15: stimulation by phorbol esters.
Topics: Animals; Cell Line; Choline; Ethanolamine; Ethanolamines; Glioma; Inositol; Neuroblastoma; Phorbol Esters; Phosphatidylcholines; Rats; Tetradecanoylphorbol Acetate | 1986 |