Page last updated: 2024-10-25

chlorzoxazone and Neuroblastoma

chlorzoxazone has been researched along with Neuroblastoma in 2 studies

Chlorzoxazone: A centrally acting central muscle relaxant with sedative properties. It is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord and subcortical areas of the brain. (From Martindale, The Extra Pharmacopoea, 30th ed, p1202)
chlorzoxazone : A member of the class of 1,3-benzoxazoles that is 1,3-benzoxazol-2-ol in which the hydrogen atom at position 5 is substituted by chlorine. A centrally acting muscle relaxant with sedative properties, it is used for the symptomatic treatment of painful muscle spasm.

Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zhong, Y1
Dong, G1
Luo, H1
Cao, J1
Wang, C1
Wu, J1
Feng, YQ1
Yue, J1
Liu, YC1
Lo, YK1
Wu, SN1

Other Studies

2 other studies available for chlorzoxazone and Neuroblastoma

ArticleYear
Induction of brain CYP2E1 by chronic ethanol treatment and related oxidative stress in hippocampus, cerebellum, and brainstem.
    Toxicology, 2012, Dec-16, Volume: 302, Issue:2-3

    Topics: Animals; Brain Stem; Cell Line, Tumor; Cerebellum; Chlorzoxazone; Cytochrome P-450 CYP2E1; Cytochrom

2012
Stimulatory effects of chlorzoxazone, a centrally acting muscle relaxant, on large conductance calcium-activated potassium channels in pituitary GH3 cells.
    Brain research, 2003, Jan-03, Volume: 959, Issue:1

    Topics: Adenoma; Animals; Chlorzoxazone; Humans; Large-Conductance Calcium-Activated Potassium Channels; Mem

2003