Page last updated: 2024-12-07

n-acetyl-4-s-cysteaminylphenol

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

N-acetyl-4-S-cysteaminylphenol: has antimelanoma effect; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID124470
SCHEMBL ID8412413
MeSH IDM0182272

Synonyms (19)

Synonym
A-1095
n-acetyl-4-s-cysteaminylphenol
n-ac-4-scap
n-[2-(4-hydroxyphenyl)sulfanylethyl]acetamide
91281-32-2
n-{2-[(4-hydroxyphenyl)sulfanyl]ethyl}acetamide
EN300-66963
AKOS010259973
acetamide, n-(2-((4-hydroxyphenyl)thio)ethyl)-
SCHEMBL8412413
n-(2-[(4-hydroxyphenyl)sulfanyl]ethyl)acetamide
acetamide, n-[2-[(4-hydroxyphenyl)thio]ethyl]-
DTXSID10238473
AS-60056
n-ac-4-s-cap
FDPFDQAWKAWHMY-UHFFFAOYSA-N
mfcd07779474
n-(2-(4-hydroxyphenylthio)ethyl)acetamide
CS-0187574

Research Excerpts

Toxicity

ExcerptReferenceRelevance
"The rationale for melanoma-specific antitumor agents containing phenolic amines is based in part on the ability of the enzyme tyrosinase to oxidize these prodrugs to toxic intermediates."( Thymidylate synthase as a target enzyme for the melanoma-specific toxicity of 4-S-cysteaminylphenol and N-acetyl-4-S-cysteaminylphenol.
Bloomer, WD; Prezioso, JA; Wang, N, 1992
)
0.5
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (18)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's11 (61.11)18.2507
2000's7 (38.89)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 21.79

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index21.79 (24.57)
Research Supply Index3.00 (2.92)
Research Growth Index4.20 (4.65)
Search Engine Demand Index21.17 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (21.79)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other19 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]