linsidomine has been researched along with Neuroblastoma in 16 studies
linsidomine: RN given refers to parent cpd; structure
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
| Excerpt | Relevance | Reference |
|---|---|---|
| "We have investigated the effect of 3-morpholinosydnonimine (SIN-1), a peroxynitrite donor, on carbachol-induced increase in intracellular Ca2+ concentration ([Ca2+]i) in human neuroblastoma SH-SY5Y cells by means of single cell imaging of [Ca2+]i." | 7.70 | Potentiation of carbachol-induced Ca2+ release by peroxynitrite in human neuroblastoma SH-SY5Y cells. ( Kamisaki, Y; Maeda, S; Saeki, M, 2000) |
| "We found that the exposure of human neuroblastoma SH-SY5Y cells to the peroxynitrite donor 3-morpholinosydnonimine (SIN-1) induced tyrosine nitration of a 130-kDa protein, and prevented tyrosine phosphorylation of the 130-kDa protein." | 3.70 | p130cas is a cellular target protein for tyrosine nitration induced by peroxynitrite. ( Maeda, S; Saeki, M, 1999) |
| "CHP212 neuroblastoma cells were exposed to two different nitric oxide (NO) donors, S-nitroso-N-acetylpenicillamine and sodium nitroprusside." | 3.70 | S-nitroso-N-acetylpenicillamine and nitroprusside induce apoptosis in a neuronal cell line by the production of different reactive molecules. ( Nieland, LJ; Ramaekers, FC; Reutelingsperger, CP; Schutte, B; Steinbusch, HW; Terwel, D, 2000) |
| "We have investigated the effect of 3-morpholinosydnonimine (SIN-1), a peroxynitrite donor, on carbachol-induced increase in intracellular Ca2+ concentration ([Ca2+]i) in human neuroblastoma SH-SY5Y cells by means of single cell imaging of [Ca2+]i." | 3.70 | Potentiation of carbachol-induced Ca2+ release by peroxynitrite in human neuroblastoma SH-SY5Y cells. ( Kamisaki, Y; Maeda, S; Saeki, M, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (31.25) | 18.2507 |
| 2000's | 9 (56.25) | 29.6817 |
| 2010's | 2 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kupershmidt, L | 1 |
| Okun, Z | 1 |
| Amit, T | 1 |
| Mandel, S | 1 |
| Saltsman, I | 1 |
| Mahammed, A | 1 |
| Bar-Am, O | 1 |
| Gross, Z | 1 |
| Youdim, MB | 1 |
| Cuddy, LK | 1 |
| Gordon, AC | 1 |
| Black, SA | 2 |
| Jaworski, E | 1 |
| Ferguson, SS | 2 |
| Rylett, RJ | 2 |
| Prasad, JE | 1 |
| Kumar, B | 1 |
| Andreatta, C | 1 |
| Nahreini, P | 1 |
| Hanson, AJ | 1 |
| Yan, XD | 1 |
| Prasad, KN | 1 |
| Wallace, DR | 1 |
| Dodson, S | 1 |
| Nath, A | 1 |
| Booze, RM | 1 |
| Lev, N | 1 |
| Melamed, E | 1 |
| Offen, D | 1 |
| Pinthong, M | 1 |
| Ribeiro, FM | 1 |
| Pholpramool, C | 1 |
| Yamasaki, T | 1 |
| Akiyama, Y | 1 |
| Fukuda, M | 1 |
| Kimura, Y | 1 |
| Moritake, K | 1 |
| Enomoto, K | 1 |
| Maeno, T | 1 |
| Maruyama, W | 3 |
| Takahashi, T | 2 |
| Naoi, M | 2 |
| Tao, YP | 1 |
| Najafi, L | 1 |
| Shipley, S | 1 |
| Howlett, A | 1 |
| Klein, C | 1 |
| Saeki, M | 3 |
| Maeda, S | 3 |
| Oh-hashi, K | 2 |
| Yi, H | 1 |
| Isobe, K | 2 |
| Terwel, D | 1 |
| Nieland, LJ | 1 |
| Schutte, B | 1 |
| Reutelingsperger, CP | 1 |
| Ramaekers, FC | 1 |
| Steinbusch, HW | 1 |
| Kamisaki, Y | 2 |
| Kim, MS | 1 |
| Lee, J | 1 |
| So, HS | 1 |
| Lee, KM | 1 |
| Moon, BS | 1 |
| Lee, HS | 1 |
| Park, R | 1 |
16 other studies available for linsidomine and Neuroblastoma
| Article | Year |
|---|---|
Metallocorroles as cytoprotective agents against oxidative and nitrative stress in cellular models of neurodegeneration.
Topics: Animals; Caspase 3; Cell Count; Cell Death; Cell Line, Tumor; Cells, Cultured; Dose-Response Relatio | 2010 |
Peroxynitrite donor SIN-1 alters high-affinity choline transporter activity by modifying its intracellular trafficking.
Topics: Cell Line, Transformed; Cell Line, Tumor; Choline; Clathrin; Cysteine Proteinase Inhibitors; Dose-Re | 2012 |
Overexpression of alpha-synuclein decreased viability and enhanced sensitivity to prostaglandin E(2), hydrogen peroxide, and a nitric oxide donor in differentiated neuroblastoma cells.
Topics: alpha-Synuclein; Animals; Cell Differentiation; Cell Survival; Dinoprostone; Dose-Response Relations | 2004 |
Estrogen attenuates gp120- and tat1-72-induced oxidative stress and prevents loss of dopamine transporter function.
Topics: Animals; Cell Line, Tumor; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; D | 2006 |
Proteasomal inhibition hypersensitizes differentiated neuroblastoma cells to oxidative damage.
Topics: alpha-Synuclein; Benzothiazoles; Cell Differentiation; Cell Line, Tumor; Cytoplasm; Ferrous Compound | 2006 |
Activity and subcellular trafficking of the sodium-coupled choline transporter CHT is regulated acutely by peroxynitrite.
Topics: Animals; Biotinylation; Cell Culture Techniques; Cell Line; Cell Line, Tumor; Cell Membrane; Choline | 2008 |
[Effects of the nitric oxide donor SIN-1 on the membrane potential of mouse neuroblastoma-rat glioma hybrid cells].
Topics: Animals; Calcium; Depression, Chemical; Glioma; Hybrid Cells; Membrane Potentials; Mice; Molsidomine | 1995 |
(-)-Deprenyl protects human dopaminergic neuroblastoma SH-SY5Y cells from apoptosis induced by peroxynitrite and nitric oxide.
Topics: Antiparkinson Agents; Apoptosis; DNA Damage; Dopamine; Electrophoresis, Agar Gel; Humans; Molsidomin | 1998 |
Effects of nitric oxide on adenylyl cyclase stimulation in N18TG2 neuroblastoma cells.
Topics: Adenylyl Cyclase Inhibitors; Animals; Calmodulin; Colforsin; Cyclic AMP; Cyclic GMP; GTP-Binding Pro | 1998 |
p130cas is a cellular target protein for tyrosine nitration induced by peroxynitrite.
Topics: Crk-Associated Substrate Protein; Humans; Molsidomine; Neuroblastoma; Nitrates; Nitric Oxide Donors; | 1999 |
Mitogen-activated protein kinase pathway mediates peroxynitrite-induced apoptosis in human dopaminergic neuroblastoma SH-SY5Y cells.
Topics: Antioxidants; Apoptosis; Calcium-Calmodulin-Dependent Protein Kinases; Caspase 3; Caspase Inhibitors | 1999 |
S-nitroso-N-acetylpenicillamine and nitroprusside induce apoptosis in a neuronal cell line by the production of different reactive molecules.
Topics: 1-Methyl-4-phenylpyridinium; Apoptosis; Catalase; Deferoxamine; Flow Cytometry; Hydrogen Peroxide; M | 2000 |
Potentiation of carbachol-induced Ca2+ release by peroxynitrite in human neuroblastoma SH-SY5Y cells.
Topics: Calcium; Carbachol; Genistein; Humans; Molsidomine; Neuroblastoma; Nitrates; Phosphorylation; Tumor | 2000 |
Peroxynitrite induces GADD34, 45, and 153 VIA p38 MAPK in human neuroblastoma SH-SY5Y cells.
Topics: Antigens, Differentiation; Antioxidants; Apoptosis; CCAAT-Enhancer-Binding Proteins; Cell Cycle Prot | 2001 |
Danchunhwan water extract prevents apoptotic death by peroxynitrite and nitric oxide in human dopaminergic neuroblastoma SH-SY5Y cells.
Topics: Antioxidants; Apoptosis; Caspase 3; Caspases; Dopamine; Drug Interactions; Drugs, Chinese Herbal; Gl | 2001 |
Vanadate protects human neuroblastoma SH-SY5Y cells against peroxynitrite-induced cell death.
Topics: Cell Death; Crk-Associated Substrate Protein; Cyclosporine; Enzyme Inhibitors; Humans; Molsidomine; | 2002 |