Page last updated: 2024-11-02

phenylmethylsulfonyl fluoride and Neuroblastoma

phenylmethylsulfonyl fluoride has been researched along with Neuroblastoma in 3 studies

Phenylmethylsulfonyl Fluoride: An enzyme inhibitor that inactivates IRC-50 arvin, subtilisin, and the fatty acid synthetase complex.
phenylmethanesulfonyl fluoride : An acyl fluoride with phenylmethanesulfonyl as the acyl group.

Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)

Research Excerpts

ExcerptRelevanceReference
"Phenylmethylsulfonyl fluoride (PMSF) was included as a non-neuropathic inhibitor of NTE."1.33Effects of organophosphorus compounds on ATP production and mitochondrial integrity in cultured cells. ( Ehrich, M; Jortner, BS; Knight, K; Massicotte, C; Van der Schyf, CJ, 2005)
"Phenylmethylsulfonyl fluoride (PMSF) was found to be a potent inhibitor of this amidase."1.29Enzymatic synthesis and degradation of anandamide, a cannabinoid receptor agonist. ( Chin, SA; Deutsch, DG, 1993)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's2 (66.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Massicotte, C1
Knight, K1
Van der Schyf, CJ1
Jortner, BS1
Ehrich, M1
Deutsch, DG1
Chin, SA1
Jacobsson, SO1
Fowler, CJ1

Other Studies

3 other studies available for phenylmethylsulfonyl fluoride and Neuroblastoma

ArticleYear
Effects of organophosphorus compounds on ATP production and mitochondrial integrity in cultured cells.
    Neurotoxicity research, 2005, Volume: 7, Issue:3

    Topics: Adenosine Triphosphate; Animals; Cells, Cultured; Chick Embryo; Cholinesterase Inhibitors; Dose-Resp

2005
Enzymatic synthesis and degradation of anandamide, a cannabinoid receptor agonist.
    Biochemical pharmacology, 1993, Sep-01, Volume: 46, Issue:5

    Topics: Amides; Animals; Arachidonic Acid; Arachidonic Acids; Brain Chemistry; Cell Line; Endocannabinoids;

1993
Characterization of palmitoylethanolamide transport in mouse Neuro-2a neuroblastoma and rat RBL-2H3 basophilic leukaemia cells: comparison with anandamide.
    British journal of pharmacology, 2001, Volume: 132, Issue:8

    Topics: Amides; Animals; Arachidonic Acids; Brain Neoplasms; Cannabinoids; Cell Survival; Endocannabinoids;

2001