procarbazine has been researched along with Neuroblastoma in 5 studies
Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Although it is accepted that pediatric cancer treatment harbors a risk of gonadal damage, large cohort studies using up-to-date fertility markers are lacking." | 1.35 | Effect of childhood cancer treatment on fertility markers in adult male long-term survivors. ( Dohle, GR; Hählen, K; Hakvoort-Cammel, FG; van Casteren, NJ; van den Heuvel-Eibrink, MM; van der Linden, GH, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| van Casteren, NJ | 1 |
| van der Linden, GH | 1 |
| Hakvoort-Cammel, FG | 1 |
| Hählen, K | 1 |
| Dohle, GR | 1 |
| van den Heuvel-Eibrink, MM | 1 |
| Einhorn, LH | 1 |
| Domeyer, C | 1 |
| Schulte-Overberg, U | 1 |
| Boll, I | 1 |
| Baumgarten, E | 1 |
| Bührer, C | 1 |
| Fengler, R | 1 |
| Henze, G | 1 |
| Seeger, RC | 1 |
| Villablanca, JG | 1 |
| Matthay, KK | 1 |
| Harris, R | 1 |
| Moss, TJ | 1 |
| Feig, SA | 1 |
| Selch, M | 1 |
| Ramsay, N | 1 |
| Reynolds, CP | 1 |
| Lawhorn, TI | 1 |
| Stone, HH | 1 |
| Martin, JD | 1 |
1 review available for procarbazine and Neuroblastoma
| Article | Year |
|---|---|
Chemotherapy in solid tumors of childhood.
Topics: Abdominal Neoplasms; Adolescent; Child; Child, Preschool; Cyclophosphamide; Dactinomycin; Eye Neopla | 1972 |
1 trial available for procarbazine and Neuroblastoma
| Article | Year |
|---|---|
Intensive chemoradiotherapy and autologous bone marrow transplantation for poor prognosis neuroblastoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Child, Preschool | 1991 |
3 other studies available for procarbazine and Neuroblastoma
| Article | Year |
|---|---|
Effect of childhood cancer treatment on fertility markers in adult male long-term survivors.
Topics: Biomarkers; Child, Preschool; Cyclophosphamide; Female; Fertility; Follicle Stimulating Hormone; Fol | 2009 |
Cancer chemotherapy.
Topics: Chlorambucil; Choriocarcinoma; Cyclophosphamide; Dactinomycin; Female; Hodgkin Disease; Humans; Leuk | 1977 |
Erythroblastopenia in two patients after splenectomy and polychemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Combined Modality Therapy; Cross Infection; C | 1991 |