enkephalin, d-penicillamine (2,5)- has been researched along with Neuroblastoma in 70 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (8.57) | 18.7374 |
| 1990's | 51 (72.86) | 18.2507 |
| 2000's | 13 (18.57) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Guo, QM; Liu, JS | 1 |
| Li, J; Li, QX; Qi, JJ; Ye, CY; Yu, XL; Zhang, DC | 2 |
| Law, PY; Loh, HH; Tetrault, J; Wang, W; Zhang, L | 1 |
| Iglewski, M; Ratka, A; Raut, A | 1 |
| Aguila, B; Allouche, S; Davis, A; Hasbi, A; Jauzac, P; Marie, N | 1 |
| Akiyama, K; Burks, TF; Galligan, JJ; Gee, K; Hruby, VJ; Hurst, R; Mosberg, HI; Yamamura, HI | 1 |
| Chang, KJ; Chung, NN; Lee, PH; Nguyen, TM; Schiller, PW | 1 |
| Fukuda, K; Higashida, H; Kato, S; Mori, K; Morikawa, H | 1 |
| Kushner, L; Tamir, M | 1 |
| Friederich, P; Hescheler, J; Nürnberg, B; Schultz, G | 1 |
| Jauzac, P; Polastron, J | 1 |
| Law, PY; Prather, PL; Tsai, AW | 1 |
| Garty, M; Keren, O; Sarne, Y | 1 |
| Graeser, D; Neubig, RR | 1 |
| Carter, BD; Medzihradsky, F | 1 |
| Jin, W; Lee, NM; Loh, HH; Thayer, SA | 2 |
| Laugwitz, KL; Offermanns, S; Schultz, G; Spicher, K | 1 |
| Crain, SM; Fan, SF; Shen, KF | 1 |
| Agarwal, D; Glasel, JA | 1 |
| Baumhaker, Y; Goldstein, MN; Sarne, Y; Wollman, Y | 1 |
| Han, JS; Ren, MF; Shun, XJ; Wang, JF; Yang, HF | 1 |
| Baumhaker, Y; Gafni, M; Keren, O; Sarne, Y | 1 |
| Hirst, RA; Lambert, DG | 1 |
| Cai, Y; Pei, G; Wu, Y; Zhang, Y | 1 |
| Lambert, DG; Smart, D | 1 |
| Amoroso, D; Catozzi, L; Ceppi, E; Groppetti, A; Guglielmetti, F; Palazzi, E | 1 |
| Burks, TF; Hruby, VJ; Roerig, SC; Rosenfeld, GC; Williams, CL | 1 |
| Chien, CC; Pasternak, GW; Ryan-Moro, J; Standifer, KM | 1 |
| Fujimoto, J; Ho, BY; Holmes, BB; Zhao, J | 1 |
| Cai, YC; Cheng, ZJ; Fan, GH; Jiang, LZ; Ma, L; Pei, G | 1 |
| Taglietti, V; Toselli, M; Tosetti, P | 1 |
| Cai, YC; Fan, GH; Jiang, LZ; Ma, L; Pei, G; Zhao, J | 1 |
| Carabelli, V; Carbone, E; Lovallo, M; Magnelli, V; Zucker, H | 1 |
| Lou, LG; Pei, G | 1 |
| Beacham, DW; Bunzow, JR; Cook, SP; Grandy, DK; Nah, SY; Unteutsch, A | 1 |
| Szekeres, PG; Traynor, JR | 1 |
| Fan, GH; Jing, Q; Lou, LG; Ma, L; Pei, G; Wu, YL; Zhang, Z; Zhao, J | 1 |
| Fields, A; Gafni, M; Rubovitch, V; Sarne, Y | 1 |
| Allen, RG; Fujimoto, KI; Nelson, CS; Pellegrino, MJ; Sirianni, MJ | 1 |
| Murphy, J; Schulz, K; Schulz, R; Wehmeyer, A | 1 |
| Allouche, S; Jauzac, P; Marie, N; Roussel, M | 1 |
| Allouche, S; Hasbi, A; Homburger, V; Jauzac, P; Polastron, J | 1 |
| Gomes, I; Gupta, A; Sharma, SK; Singh, SP | 1 |
| Ma, L; Pei, G; Wu, GX; Xin, SM; Zhang, WB; Zhang, Z | 1 |
| Gafni, M; Keren, O; Sarne, Y | 1 |
| Li, J; Li, X; Pei, G; Qin, BY | 1 |
| Allouche, S; Ferey, V; Hasbi, A; Jauzac, P; Polastron, J; Sola, B | 1 |
| Sarne, Y; Shapira, M; Vogel, Z | 1 |
| Chen, ZW; Han, JS; Wang, Y; Yang, K | 2 |
| Fowler, CE; Gunn-Moore, F; Henderson, G; Samways, DS; Yeo, A | 1 |
| Han, JS; Wang, XM; Wang, Y | 1 |
| Flati, S; Guzzi, F; Parente, V; Parenti, M; Pavan, A; Taglietti, V; Toselli, M | 1 |
| Alt, A; Clark, MJ; Traynor, JR; Woods, JH | 1 |
| Law, PY; Loh, HH; Roerig, SC | 1 |
| Anthony, E; Beardsley, PM; Chandrakumar, NS; Drury, B; Lopez, OT; Reichman, M; Savage, MA; Stapelfeld, A; Williamson, LN | 1 |
| Costa, EM; Hoffman, BB; Loew, GH | 1 |
| Crain, SM; Fan, SF; Scheideler, MA; Shen, KF | 1 |
| Gnegy, ME; Mangels, LA | 1 |
| Han, JS; Ren, MF; Sun, XJ; Wang, JF; Yang, HF | 1 |
| Kasai, H | 1 |
| Cone, RI; Lameh, J; Sadée, W | 1 |
| Duan, DS; Eiger, S; Lameh, J; Sadée, W; Yu, VC | 1 |
| Bidlack, JM; Selley, DE | 1 |
| Bidlack, JM; O'Malley, WE; Schulz, R | 1 |
| Delay-Goyet, P; Foucaud, B; Rigaudy, P; Roques, BP; Zajac, JM | 1 |
| Akiyama, K; Gee, KW; Hruby, VJ; Mosberg, HI; Yamamura, HI | 1 |
| Kazmi, SM; Mishra, RK | 1 |
70 other study(ies) available for enkephalin, d-penicillamine (2,5)- and Neuroblastoma
| Article | Year |
|---|---|
[Effects of opioids on Ca2+/calmodulin dependent protein kinase signal pathway in NG108-15 cells].
Topics: Analgesics, Opioid; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Cell Nucleus; Cyclic AMP; Cytoplasm; Enkephalin, D-Penicillamine (2,5)-; Glioma; Hybrid Cells; Mice; Neuroblastoma; Rats; Signal Transduction | 2001 |
[Dual regulation by delta opioid receptor agonists on the delayed rectified potassium channels in NG108-15 cells].
Topics: Animals; Cell Membrane; Enkephalin, D-Penicillamine (2,5)-; Glioma; Hybrid Cells; Mice; Naloxone; Naltrexone; Neuroblastoma; Patch-Clamp Techniques; Potassium Channels, Inwardly Rectifying; Rats; Receptors, Opioid, delta; Tumor Cells, Cultured | 2003 |
[Effect of G protein in the dual regulation of opioid receptor agonist on the delayed rectified potassium channels].
Topics: Animals; Enkephalin, D-Penicillamine (2,5)-; Glioma; GTP-Binding Proteins; Guanosine Monophosphate; Hybrid Cells; Mice; Neuroblastoma; Patch-Clamp Techniques; Pertussis Toxin; Potassium Channels, Inwardly Rectifying; Rats; Receptors, Opioid; Thionucleotides | 2003 |
Short- and long-term regulation of adenylyl cyclase activity by delta-opioid receptor are mediated by Galphai2 in neuroblastoma N2A cells.
Topics: Adenoviridae; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Cyclic AMP; Enkephalin, D-Penicillamine (2,5)-; GTP-Binding Protein alpha Subunit, Gi2; Immunoprecipitation; Mice; Naloxone; Neuroblastoma; Pertussis Toxin; Receptors, Opioid, delta; Tumor Cells, Cultured | 2006 |
Differential effects of impaired mitochondrial energy production on the function of mu and delta opioid receptors in neuronal SK-N-SH cells.
Topics: Cell Line, Tumor; Energy Metabolism; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Humans; Mitochondria; Neuroblastoma; Neurons; Nitro Compounds; Propionates; Reactive Oxygen Species; Receptors, Opioid, delta; Receptors, Opioid, mu | 2006 |
Different kinases desensitize the human delta-opioid receptor (hDOP-R) in the neuroblastoma cell line SK-N-BE upon peptidic and alkaloid agonists.
Topics: Analgesics, Opioid; Cell Line, Tumor; Cyclic AMP-Dependent Protein Kinases; Enkephalin, D-Penicillamine (2,5)-; Etorphine; G-Protein-Coupled Receptor Kinase 2; Humans; Mutation; Neuroblastoma; Oligopeptides; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Protein-Tyrosine Kinases; Receptors, Opioid, delta | 2008 |
Cyclic penicillamine containing enkephalin analogs display profound delta receptor selectivities.
Topics: Animals; Brain; Cell Line; Cell Membrane; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Glioma; Guinea Pigs; Hybrid Cells; Ileum; Male; Mice; Muscle Contraction; Neuroblastoma; Rats; Receptors, Opioid; Receptors, Opioid, delta; Structure-Activity Relationship; Vas Deferens | 1983 |
Tyrosine-iodination converts the delta-opioid peptide antagonist TIPP to an agonist.
Topics: Amino Acid Sequence; Analgesics; Animals; Brain Neoplasms; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Humans; Iodine; Mice; Molecular Sequence Data; Molecular Weight; Narcotic Antagonists; Neuroblastoma; Oligopeptides; Receptors, Opioid, delta; Spectrometry, Mass, Fast Atom Bombardment; Tetrahydroisoquinolines; Tumor Cells, Cultured; Tyrosine | 1995 |
Coupling of the cloned mu-opioid receptor with the omega-conotoxin-sensitive Ca2+ current in NG108-15 cells.
Topics: Animals; Calcium Channels; Cloning, Molecular; DNA, Complementary; Electric Conductivity; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Gene Expression; Glioma; GTP-Binding Proteins; Hybrid Cells; Neuroblastoma; omega-Conotoxin GVIA; Peptides; Pertussis Toxin; Rats; Receptors, Opioid, mu; Transfection; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1995 |
Expression of functional delta opioid receptors in Xenopus oocytes.
Topics: Adenylyl Cyclases; Analgesics; Analysis of Variance; Animals; Cyclic AMP; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Female; Glioma; Hybrid Cells; Isoproterenol; Mice; Naltrexone; Neuroblastoma; Oocytes; Poly A; Rats; Receptors, Opioid, delta; RNA; RNA, Messenger; Xenopus laevis | 1993 |
Inversion of Ca2+ current modulation during recovery of neuroblastoma cells from pertussis toxin pretreatment.
Topics: Calcium; Cell Differentiation; Dopamine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Humans; Membrane Potentials; Neuroblastoma; Pertussis Toxin; Somatostatin; Tretinoin; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1993 |
Different subtypes of opioid receptors have different affinities for G-proteins.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adenylyl Cyclases; Amino Acid Sequence; Animals; Binding, Competitive; Cerebellum; Colforsin; Diprenorphine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Etorphine; GTP-Binding Proteins; Guinea Pigs; Humans; Hybrid Cells; Molecular Sequence Data; Morphine; Naloxone; Neoplasm Proteins; Nerve Tissue Proteins; Neuroblastoma; Oligopeptides; Pyrrolidines; Rabbits; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Tumor Cells, Cultured | 1994 |
Mu and delta opioid receptor desensitization in undifferentiated human neuroblastoma SHSY5Y cells.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Analgesics; Cell Differentiation; Colforsin; Cyclic AMP; Endorphins; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Humans; Neuroblastoma; Neurons; Receptors, Opioid, delta; Receptors, Opioid, mu; Sensitivity and Specificity; Signal Transduction; Stimulation, Chemical; Tumor Cells, Cultured | 1994 |
Dual regulation by opioids of 3H-norepinephrine release in the human neuroblastoma cell-line SK-N-SH.
Topics: Cell Line; Dextrorphan; Drug Interactions; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Humans; Kinetics; Levorphanol; Morphine; Naloxone; Narcotics; Neuroblastoma; Norepinephrine; Receptors, Opioid; Tritium; Tumor Cells, Cultured | 1994 |
Compartmentation of receptors and guanine nucleotide-binding proteins in NG108-15 cells: lack of cross-talk in agonist binding among the alpha 2-adrenergic, muscarinic, and opiate receptors.
Topics: Adrenergic alpha-Agonists; Animals; Binding Sites; Cell Compartmentation; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Glioma; GTP-Binding Proteins; Mathematics; Neuroblastoma; Oxotremorine; Parasympathomimetics; Receptors, Adrenergic, alpha; Receptors, Muscarinic; Receptors, Opioid; Signal Transduction | 1993 |
Go mediates the coupling of the mu opioid receptor to adenylyl cyclase in cloned neural cells and brain.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Analgesics; Animals; Antibodies; Cell Membrane; Clone Cells; Corpus Striatum; Cyclic AMP; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; GTP-Binding Proteins; Humans; Kinetics; Membrane Proteins; Neuroblastoma; Pertussis Toxin; Rats; Receptors, Opioid, mu; Somatostatin; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1993 |
Opioids mobilize calcium from inositol 1,4,5-trisphosphate-sensitive stores in NG108-15 cells.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Calcium; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Fluorescent Dyes; Fura-2; Glioma; Hybrid Cells; Inositol 1,4,5-Trisphosphate; Kinetics; Mice; Microscopy, Fluorescence; Naloxone; Narcotics; Neuroblastoma; Pyrrolidines; Rats; Tumor Cells, Cultured | 1994 |
mu and delta opioid receptors differentially couple to G protein subtypes in membranes of human neuroblastoma SH-SY5Y cells.
Topics: Affinity Labels; Azides; Cell Membrane; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; GTP-Binding Proteins; Guanosine Triphosphate; Humans; Immunosorbent Techniques; Neuroblastoma; Pertussis Toxin; Photochemistry; Receptors, Opioid, delta; Receptors, Opioid, mu; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1993 |
mu and delta opioid agonists at low concentrations decrease voltage-dependent K+ currents in F11 neuroblastoma x DRG neuron hybrid cells via cholera toxin-sensitive receptors.
Topics: Animals; Cholera Toxin; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Ganglia, Spinal; Hybrid Cells; Membrane Potentials; Neuroblastoma; Neurons; Pertussis Toxin; Potassium Channels; Rats; Receptors, Opioid, delta; Receptors, Opioid, mu; Virulence Factors, Bordetella | 1993 |
Co-localization of mu and delta opioid receptors on SK-N-SH cells detected by fluorescence microscopy using labeled anti-idiotypic antibodies.
Topics: Antibodies, Anti-Idiotypic; Binding, Competitive; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Humans; Microscopy, Fluorescence; Neuroblastoma; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Tumor Cells, Cultured | 1993 |
Evidence for mu-, delta-, and kappa-opioid receptors in a human neuroblastoma cell line.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Binding, Competitive; Diprenorphine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Humans; Kinetics; Neuroblastoma; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sensitivity and Specificity; Tritium; Tumor Cells, Cultured | 1993 |
Suppression by [D-Pen2, D-Pen5]enkephalin on cyclic AMP dependent protein kinase-induced, but not protein kinase C-induced increment of intracellular free calcium in NG108-15 cells.
Topics: Analgesics; Animals; Bucladesine; Calcium; Calcium Channels; Colforsin; Depression, Chemical; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Glioma; Hybrid Cells; Intracellular Fluid; Mice; Neuroblastoma; Potassium Chloride; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Rats; Receptors, Opioid, delta; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Selective and interactive down-regulation of mu- and delta-opioid receptors in human neuroblastoma SK-N-SH cells.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Down-Regulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Humans; Morphine; Naltrexone; Neuroblastoma; Pyrrolidines; Receptors, Opioid, delta; Receptors, Opioid, mu; Tumor Cells, Cultured | 1993 |
Do SH-SY5Y human neuroblastoma cells express cannabinoid receptors?
Topics: Adenylyl Cyclase Inhibitors; Cannabinoids; Colforsin; Cyclic AMP; Dronabinol; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Humans; Neuroblastoma; Potassium; Receptors, Cannabinoid; Receptors, Drug; Receptors, Opioid; Tumor Cells, Cultured | 1995 |
delta Opioid receptor in neuronal cells undergoes acute and homologous desensitization.
Topics: 1-Methyl-3-isobutylxanthine; Analgesics; Animals; Cerebral Cortex; Cyclic AMP; Dose-Response Relationship, Drug; Embryo, Mammalian; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Glioma; Hybrid Cells; Kinetics; Mice; Neuroblastoma; Neurons; Rats; Receptors, Opioid, delta; Time Factors; Tumor Cells, Cultured | 1996 |
delta-Opioids stimulate inositol 1,4,5-trisphosphate formation, and so mobilize Ca2+ from intracellular stores, in undifferentiated NG108-15 cells.
Topics: Analgesics; Animals; Calcium; Calcium Channel Blockers; Dose-Response Relationship, Drug; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Glioma; Inositol 1,4,5-Trisphosphate; Neuroblastoma; Nickel; Nifedipine; Pertussis Toxin; Receptors, Opioid, delta; Tumor Cells, Cultured; Type C Phospholipases; Virulence Factors, Bordetella | 1996 |
Biochemical evidence of functional interaction between mu- and delta-opioid receptors in SK-N-BE neuroblastoma cell line.
Topics: Adenylyl Cyclases; Analgesics; Binding, Competitive; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Enkephalins; Humans; Membrane Proteins; Neuroblastoma; Receptors, Opioid, delta; Receptors, Opioid, mu; Time Factors; Tumor Cells, Cultured | 1996 |
Inhibition of adenylyl cyclase activity by the cholecystokinin analog SNF 9007 in neuroblastoma x glioma NG108-15 hybrid cells.
Topics: Adenylyl Cyclase Inhibitors; Amino Acid Sequence; Analgesics; Cholecystokinin; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Enzyme Inhibitors; Glioma; Hybrid Cells; Molecular Sequence Data; Neuroblastoma; Oligopeptides; Pain; Peptide Fragments; Receptors, Opioid, delta | 1996 |
Sigma binding in a human neuroblastoma cell line.
Topics: Adenylyl Cyclases; Analgesics; Analysis of Variance; Animals; Binding, Competitive; Brain; Carbachol; Cell Line; Colforsin; Cyclic AMP; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Guanylyl Imidodiphosphate; Guinea Pigs; Haloperidol; Humans; Kinetics; Morphine; Naloxone; Neuroblastoma; Pentazocine; Phosphatidylinositols; Receptors, Opioid; Receptors, sigma; Trypsin; Tumor Cells, Cultured | 1996 |
Determination of delta-opioid in NG108-15 cells.
Topics: Animals; Benzylidene Compounds; Cyclic AMP; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Glioma; Mice; Naltrexone; Neuroblastoma; Rats; Receptors, Opioid, delta; Tumor Cells, Cultured | 1997 |
Functional expression, activation and desensitization of opioid receptor-like receptor ORL1 in neuroblastoma x glioma NG108-15 hybrid cells.
Topics: Colforsin; Cyclic AMP; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Glioma; GTP-Binding Proteins; Hybrid Cells; Naltrexone; Narcotic Antagonists; Neuroblastoma; Nociceptin; Nociceptin Receptor; Opioid Peptides; Pertussis Toxin; Receptors, Opioid; Receptors, Opioid, delta; Virulence Factors, Bordetella | 1997 |
Mu and delta opioid receptor activation inhibits omega-conotoxin-sensitive calcium channels in a voltage- and time-dependent mode in the human neuroblastoma cell line SH-SY5Y.
Topics: Barium; Calcium Channels; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Neuroblastoma; Receptors, Opioid, delta; Receptors, Opioid, mu; Tumor Cells, Cultured | 1997 |
Activation of N-methyl-D-aspartate receptor attenuates acute responsiveness of delta-opioid receptors.
Topics: Analgesics; Animals; CHO Cells; Cricetinae; Cyclic AMP-Dependent Protein Kinases; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glioma; Ketamine; Mice; N-Methylaspartate; Neuroblastoma; Neurons; Phosphorylation; Protein Kinase C; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, delta; Signal Transduction | 1997 |
Voltage-dependent modulation of single N-Type Ca2+ channel kinetics by receptor agonists in IMR32 cells.
Topics: Barium; Calcium Channel Agonists; Calcium Channels; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Humans; Ion Channel Gating; Kinetics; Membrane Potentials; Models, Chemical; Neuroblastoma; Norepinephrine; Patch-Clamp Techniques; Tumor Cells, Cultured | 1996 |
Modulation of protein kinase C and cAMP-dependent protein kinase by delta-opioid.
Topics: Calcium; Cyclic AMP-Dependent Protein Kinases; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Enzyme Activation; Glioma; Hybrid Cells; Kinetics; Neuroblastoma; Pertussis Toxin; Protein Kinase C; Receptors, Opioid, delta; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1997 |
Mu and delta opioids but not kappa opioid inhibit voltage-activated Ba2+ currents in neuronal F-11 cell.
Topics: Analgesics; Analgesics, Opioid; Animals; Barium; Calcium; Calcium Channel Blockers; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Ethylmaleimide; Gene Expression Regulation; Hybrid Cells; Ion Channel Gating; Mice; Neuroblastoma; omega-Conotoxin GVIA; Patch-Clamp Techniques; Peptides; Pertussis Toxin; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; RNA, Messenger; Sulfhydryl Reagents; Virulence Factors, Bordetella | 1997 |
Delta opioid modulation of the binding of guanosine-5'-O-(3-[35S]thio)triphosphate to NG108-15 cell membranes: characterization of agonist and inverse agonist effects.
Topics: Animals; Benzylidene Compounds; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Guanosine 5'-O-(3-Thiotriphosphate); Mice; Naltrexone; Neuroblastoma; Rats; Receptors, Opioid, delta; Sodium | 1997 |
N-Methyl-D-aspartate attenuates opioid receptor-mediated G protein activation and this process involves protein kinase C.
Topics: Animals; Cells, Cultured; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Enzyme Activation; GTP-Binding Proteins; Humans; Mice; Mutagenesis, Site-Directed; N-Methylaspartate; Neuroblastoma; Neurons; Phosphorylation; Protein Kinase C; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1998 |
Dissociation between the inhibitory and stimulatory effects of opioid peptides on cAMP formation in SK-N-SH neuroblastoma cells.
Topics: Calcium; Cyclic AMP; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; GTP-Binding Proteins; Humans; Kinetics; Neuroblastoma; Opioid Peptides; Receptors, Opioid, delta; Receptors, Opioid, mu; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1998 |
Cyclic AMP analogs induce synthesis, processing, and secretion of prepro nociceptin/orphanin FQ-derived peptides by NS20Y neuroblastoma cells.
Topics: Animals; Cell Size; Chromatography, High Pressure Liquid; Colforsin; Cyclic AMP; Dexamethasone; Dose-Response Relationship, Drug; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Mice; Narcotics; Neurites; Neuroblastoma; Neurons; Nociceptin; Opioid Peptides; Peptide Fragments; Radioimmunoassay; Receptors, Opioid, delta; RNA, Messenger; Signal Transduction; Thionucleotides; Time Factors; Tumor Cells, Cultured | 1999 |
Effect of phosducin on opioid receptor function.
Topics: Cyclic AMP; DNA; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Eye Proteins; Flow Cytometry; Glioma; Green Fluorescent Proteins; GTP Phosphohydrolases; GTP-Binding Protein Regulators; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Hybrid Cells; Luminescent Proteins; Microscopy, Confocal; Nerve Tissue Proteins; Neuroblastoma; Phosphoproteins; Radioligand Assay; Receptors, Opioid; Recombinant Fusion Proteins; Transfection; Tumor Cells, Cultured | 1999 |
Differential desensitization of human delta-opioid receptors by peptide and alkaloid agonists.
Topics: Adenylyl Cyclase Inhibitors; Alkaloids; Analgesics; Analgesics, Opioid; Cyclic AMP; Drug Interactions; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Etorphine; Humans; Naloxone; Neuroblastoma; Oligopeptides; Peptides; Receptors, Opioid, delta; Tumor Cells, Cultured | 1999 |
Differential G-protein activation by alkaloid and peptide opioid agonists in the human neuroblastoma cell line SK-N-BE.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Alkaloids; Animals; Azides; Cell Membrane; Colforsin; Cyclic AMP; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Etorphine; GTP-Binding Proteins; Guanosine Triphosphate; Humans; Isoelectric Point; Neuroblastoma; Neurons; Oligodeoxyribonucleotides, Antisense; Oligopeptides; Peptides; Pertussis Toxin; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1999 |
Monoclonal antibody to the delta opioid receptor acts as an agonist in dual regulation of adenylate cyclase in NG108-15 cells.
Topics: Adenylyl Cyclases; Alprostadil; Amino Acid Sequence; Animals; Antibodies, Monoclonal; Blotting, Western; Cyclic AMP; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Epitopes; Fluorescent Antibody Technique; Glioma; Molecular Sequence Data; Neuroblastoma; Precipitin Tests; Receptors, Opioid, delta; Tumor Cells, Cultured | 1999 |
Endogenous delta-opioid and ORL1 receptors couple to phosphorylation and activation of p38 MAPK in NG108-15 cells and this is regulated by protein kinase A and protein kinase C.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cyclic AMP-Dependent Protein Kinases; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Enzyme Activation; Enzyme Inhibitors; Glioma; Hybrid Cells; Imidazoles; Kinetics; Mitogen-Activated Protein Kinases; Neuroblastoma; Nociceptin Receptor; p38 Mitogen-Activated Protein Kinases; Pertussis Toxin; Phosphorylation; Protein Kinase C; Pyridines; Receptors, Opioid; Receptors, Opioid, delta; Recombinant Proteins; Transfection; Virulence Factors, Bordetella | 1999 |
Potentiation of transmitter release from NMB human neuroblastoma cells by kappa-opioids is mediated by N-type voltage-dependent calcium channels.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Calcium Channel Blockers; Calcium Channels, N-Type; Dopamine; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Humans; Neuroblastoma; omega-Conotoxins; Pertussis Toxin; Potassium Cyanide; Receptors, Opioid, kappa; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1999 |
Influence of agmatine in adaptation of cAMP signal transduction system of opiate receptors.
Topics: Adaptation, Physiological; Adrenergic alpha-Antagonists; Agmatine; Analgesics; Animals; Cyclic AMP; Enkephalin, D-Penicillamine (2,5)-; Glioma; Guanosine 5'-O-(3-Thiotriphosphate); Hybrid Cells; Idazoxan; Imidazoline Receptors; Mice; Morphine; Neuroblastoma; Rats; Receptors, Drug; Signal Transduction; Tumor Cells, Cultured | 1999 |
Pharmacological delta1- and delta2-opioid receptor subtypes in the human neuroblastoma cell line SK-N-BE: no evidence for distinct molecular entities.
Topics: Adenylyl Cyclases; Analgesics, Opioid; Binding, Competitive; Enkephalin, D-Penicillamine (2,5)-; GTP-Binding Proteins; Humans; Neuroblastoma; Oligopeptides; Receptors, Opioid, delta; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured | 2000 |
Opioid and cannabinoid receptors share a common pool of GTP-binding proteins in cotransfected cells, but not in cells which endogenously coexpress the receptors.
Topics: Analgesics; Analgesics, Opioid; Animals; COS Cells; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Etorphine; Gene Expression; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine 5'-O-(3-Thiotriphosphate); Heterotrimeric GTP-Binding Proteins; Neuroblastoma; Phenanthridines; Radioligand Assay; Receptors, Cannabinoid; Receptors, Drug; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Signal Transduction; Sulfur Radioisotopes; Transfection; Tumor Cells, Cultured | 2000 |
The metabolic evidence of synergistic effect between ohmefentanyl and [D-Pen2, D-Pen5] enkephalin on differentiated SH-SY5Y cells in humans.
Topics: Acids; Analgesics; Analgesics, Opioid; Animals; Cell Differentiation; CHO Cells; Cricetinae; Drug Synergism; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Extracellular Space; Fentanyl; Humans; Naloxone; Narcotic Antagonists; Neuroblastoma; Neurons; Tumor Cells, Cultured | 2001 |
Coincident signalling between the Gi/Go-coupled delta-opioid receptor and the Gq-coupled m3 muscarinic receptor at the level of intracellular free calcium in SH-SY5Y cells.
Topics: Animals; Calcium; Carbachol; CHO Cells; Cricetinae; Enkephalin, D-Penicillamine (2,5)-; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gq-G11; Heterotrimeric GTP-Binding Proteins; Humans; Kinetics; Neuroblastoma; Oxotremorine; Receptor Cross-Talk; Receptor, Muscarinic M3; Receptors, Muscarinic; Receptors, Opioid, delta; Transfection; Tumor Cells, Cultured | 2001 |
The metabolic evidence of synergistic interaction between DAMGO and DPDPE on undifferentiated SH-SY5Y cells.
Topics: Analgesics, Opioid; Animals; Cell Differentiation; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Drug Synergism; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Humans; Neuroblastoma; Neurons; Receptors, Opioid, delta; Receptors, Opioid, mu; Time Factors; Tumor Cells, Cultured | 2001 |
[Inhibition of the expression of delta opioid receptor mRNA by long-term exposure of NG-108-15 cell line to delta opioid agonists].
Topics: Analgesics, Opioid; Animals; Benzamides; Enkephalin, D-Penicillamine (2,5)-; Gene Expression; Glioma; Hybrid Cells; Mice; Neuroblastoma; Piperazines; Rats; Receptors, Opioid, delta; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Tumor Cells, Cultured | 1998 |
Attenuation of G protein-mediated inhibition of N-type calcium currents by expression of caveolins in mammalian NG108-15 cells.
Topics: Analgesics, Opioid; Animals; Calcium Channels, N-Type; Caveolin 1; Caveolin 3; Caveolins; Electrophysiology; Enkephalin, D-Penicillamine (2,5)-; Gene Expression; Glioma; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Hybrid Cells; Membrane Potentials; Neuroblastoma; Neurons; Rats; Recombinant Proteins | 2001 |
Mu and Delta opioid receptors activate the same G proteins in human neuroblastoma SH-SY5Y cells.
Topics: Adenylyl Cyclases; Analgesics, Opioid; Benzamides; Cyclic AMP; Dose-Response Relationship, Drug; Drug Interactions; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Ligands; Neuroblastoma; Piperazines; Receptors, Opioid, delta; Receptors, Opioid, mu; Sulfur Radioisotopes; Tumor Cells, Cultured | 2002 |
Identification of three separate guanine nucleotide-binding proteins that interact with the delta-opioid receptor in NG108-15 neuroblastoma x glioma hybrid cells.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Analgesics; Animals; Autoradiography; Cell Line; Cell Membrane; Cholera Toxin; Electrophoresis, Polyacrylamide Gel; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Glioma; GTP-Binding Proteins; Hybrid Cells; Kinetics; Mice; Molecular Weight; Neuroblastoma; Pertussis Toxin; Phosphorus Radioisotopes; Rats; Receptors, Opioid; Receptors, Opioid, delta; Virulence Factors, Bordetella | 1992 |
Analogs of the delta opioid receptor selective cyclic peptide [2-D-penicillamine,5-D-penicillamine]-enkephalin: 2',6'-dimethyltyrosine and Gly3-Phe4 amide bond isostere substitutions.
Topics: Amides; Amino Acid Sequence; Analgesics; Animals; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Glycine; Male; Mice; Molecular Sequence Data; Muscle Contraction; Neuroblastoma; Peptides, Cyclic; Phenylalanine; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Structure-Activity Relationship; Substrate Specificity; Tumor Cells, Cultured; Tyrosine; Vas Deferens | 1992 |
Assessment of delta-opioid receptor activation by a series of peptides in cultured cells.
Topics: Amino Acid Sequence; Binding, Competitive; Cell Membrane; Cyclic AMP; Endorphins; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Glioma; GTP Phosphohydrolases; Hybrid Cells; Molecular Sequence Data; Neuroblastoma; Protein Conformation; Receptors, Opioid, delta; Structure-Activity Relationship; Tumor Cells, Cultured | 1992 |
F11 neuroblastoma x DRG neuron hybrid cells express inhibitory mu- and delta-opioid receptors which increase voltage-dependent K+ currents upon activation.
Topics: Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Hybrid Cells; Mice; Neuroblastoma; Neurons; Potassium Channels; Radioligand Assay; Rats; Receptors, Opioid, delta; Receptors, Opioid, mu; Spinal Cord | 1992 |
Dual excitatory and inhibitory effects of opioids on intracellular calcium in neuroblastoma x glioma hybrid NG108-15 cells.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Bucladesine; Calcium; Calcium Channels; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Glioma; Hybrid Cells; Ion Channel Gating; Narcotics; Neuroblastoma; Phorbol 12,13-Dibutyrate; Pyrrolidines; Receptors, Opioid, delta; Tumor Cells, Cultured | 1992 |
Cyclic AMP accumulation alters calmodulin localization in SK-N-SH human neuroblastoma cells.
Topics: Adenylyl Cyclases; Adrenergic alpha-Agonists; Alprostadil; Analgesics; Brimonidine Tartrate; Bucladesine; Calcium; Calmodulin; Carbachol; Cell Line; Colforsin; Cyclic AMP; Cytosol; Edetic Acid; Egtazic Acid; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Humans; Kinetics; Neuroblastoma; Quinoxalines; Tumor Cells, Cultured; Vasoactive Intestinal Peptide | 1992 |
Mobilization of calcium from intracellular store as a possible mechanism underlying the anti-opioid effect of angiotensin II.
Topics: Angiotensin II; Calcium; Endorphins; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Naloxone; Neuroblastoma; Potassium Chloride; Saralasin; Tumor Cells, Cultured | 1992 |
Tonic inhibition and rebound facilitation of a neuronal calcium channel by a GTP-binding protein.
Topics: Animals; Calcium Channels; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Ethylmaleimide; GTP-Binding Proteins; In Vitro Techniques; Membrane Potentials; Mollusk Venoms; Neuroblastoma; Neurons; Peptides, Cyclic; Pertussis Toxin; Rats; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1991 |
Rapid agonist-induced loss of 125I-beta-endorphin opioid receptor sites in NG108-15, but not SK-N-SH neuroblastoma cells.
Topics: Analgesics; Animals; beta-Endorphin; Binding Sites; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Humans; Mice; Neuroblastoma; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Tumor Cells, Cultured | 1991 |
Regulation of cyclic AMP by the mu-opioid receptor in human neuroblastoma SH-SY5Y cells.
Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Cell Line; Colforsin; Cyclic AMP; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Humans; Kinetics; Morphine; Neuroblastoma; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Theophylline; Vasoactive Intestinal Peptide | 1990 |
Guanine nucleotide regulation of [125I]beta-endorphin binding to NG108-15 and SK-N-SH cell membranes: specific cation requirements.
Topics: beta-Endorphin; Cations; Cell Membrane; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Glioma; Guanine Nucleotides; Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Humans; Hybrid Cells; Neuroblastoma; Oligopeptides; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Sodium Chloride; Tumor Cells, Cultured | 1989 |
Comparison of [125I]beta-endorphin binding to rat brain and NG108-15 cells using a monoclonal antibody directed against the opioid receptor.
Topics: Animals; Antibodies, Monoclonal; beta-Endorphin; Brain; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Glioma; Immunoglobulin M; In Vitro Techniques; Iodine Radioisotopes; Male; Molecular Weight; Neuroblastoma; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Tumor Cells, Cultured | 1988 |
Comparative binding properties of linear and cyclic delta-selective enkephalin analogues: [3H]-[D-Thr2, Leu5] enkephalyl-Thr6 and [3H]-[D-Pen2, D-Pen5] enkephalin.
Topics: Animals; Brain; Cell Line; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Glioma; Guinea Pigs; Isomerism; Kinetics; Neuroblastoma; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta | 1985 |
Characterization of [3H][2-D-penicillamine, 5-D-penicillamine]-enkephalin binding to delta opiate receptors in the rat brain and neuroblastoma--glioma hybrid cell line (NG 108-15).
Topics: Animals; Brain; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Glioma; Hybrid Cells; Kinetics; Membranes; Mice; Neuroblastoma; Rats; Receptors, Opioid; Receptors, Opioid, delta | 1985 |
Comparative pharmacological properties and functional coupling of mu and delta opioid receptor sites in human neuroblastoma SH-SY5Y cells.
Topics: Binding, Competitive; Cell Line; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Humans; Kinetics; Narcotics; Neuroblastoma; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu | 1987 |