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trimethylenediamine and Neuroblastoma

trimethylenediamine has been researched along with Neuroblastoma in 4 studies

trimethylenediamine: RN given refers to parent cpd; structure
trimethylenediamine : An alkane-alpha,omega-diamine comprising a propane skeleton with amino substituents at positions 1 and 3.

Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)

Research Excerpts

ExcerptRelevanceReference
"Neuroblastoma-inoculated A/J mice were treated with various anticancer chemotherapeutic agents, including cyclophosphamide, daunorubicin, vincristine, alpha-bungarotoxin, dihydroxytryptamine, and diaminopropane."3.66Chemotherapy of neuroblastoma in mice with anticancer agents. ( Chiou, GC; Martin, MK, 1980)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19904 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chapman, SK2
Glant, SK1
Chiou, GC2
Martin, MK1
Martin, M1
Hoover, MS1
Chiou, CY1
Rohde, BH1

Other Studies

4 other studies available for trimethylenediamine and Neuroblastoma

ArticleYear
Antiproliferative effects of inhibitors of polyamine synthesis in tumors of neural origin.
    Journal of pharmaceutical sciences, 1980, Volume: 69, Issue:6

    Topics: Animals; Antineoplastic Agents; Cadaverine; Cell Division; Cell Line; Diamines; Glioma; Mice; Neopla

1980
Chemotherapy of neuroblastoma in mice with anticancer agents.
    Journal of pharmaceutical sciences, 1980, Volume: 69, Issue:5

    Topics: 5,6-Dihydroxytryptamine; Acetates; Acetylcholine; Animals; Antineoplastic Agents; Bungarotoxins; Cyc

1980
Ornithine decarboxylase activity and the growth of neuroblastoma cells. The effects of bromoacetylcholine, bromoacetate and 1,3-diaminopropane.
    Biochemical pharmacology, 1978, Mar-01, Volume: 27, Issue:5

    Topics: Acetates; Acetylcholine; Carboxy-Lyases; Cell Division; Cells, Cultured; Diamines; Neoplasm Proteins

1978
Effects of glucose on neuroblastoma in vitro and in vivo.
    Journal of pharmaceutical sciences, 1987, Volume: 76, Issue:5

    Topics: Acetylcholine; Animals; Blood Glucose; Cell Line; Combined Modality Therapy; Cyclophosphamide; Diami

1987