Compounds > iprindole
Page last updated: 2024-09-22

iprindole

Description

Iprindole: A tricyclic antidepressant that has actions and uses similar to those of AMITRIPTYLINE, but has only weak antimuscarinic and sedative effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p257) [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID21722
CHEMBL ID126224
CHEBI ID135177
SCHEMBL ID49509
MeSH IDM0011703

Synonyms (71)

Synonym
tertran
5h-cyclooct[b]indole,7,8,9,10,11-hexahydro-
prondol
5h-cyclooct[b]indole,7,8,9,10,11-hexahydro-5-(3-dimethylaminopropyl)-
nsc-169449
galatur
wln: t b658 hn&&tj h3n1&1
wln: t c658 bn&&tj b3n1&1
pramindole
nsc169449
5h-cyclooct[b]indole-5-propanamine,7,8,9,10,11,hexahydro-n,n-dimethyl-
5h-cyclooct[b]indole-5-propanamine,7,8,9,10,11-hexahydro-n,n-dimethyl-
iprindole
1-(3-dimethylaminopropyl)-2,3-hexamethyleneindole
5560-72-5
5-[3-(dimethylamino)propyl]-6,8,9,10,11-hexahydro-5h-cyclooct[b]indole
wy-3263
5h-cyclooct[b]indole-5-propanamine, 6,7,8,9,10,11-hexahydro-n,n-dimethyl-
iprindolum [inn-latin]
nsc 169449
einecs 226-933-5
brn 1386299
wy-3263 (van)
5h-cyclooct(b)indole-5-propanamine, 6,7,8,9,10,11-hexahydro-n,n-dimethyl-
5-(3-(dimethylamino)propyl)-6,7,8,9,10,11-hexahydro-5h-cyclooct(b)indole
iprindol [inn-spanish]
5h-cyclooct(b)indole, 5-(3-(dimethylamino)propyl)-6,7,8,9,10,11-hexahydro-
PDSP1_001610
{5h-cyclooct[b]indole,} {5-[3-(dimethylamino)propyl]-6,7,8,9,10,11-hexahydro-}
{5-[3-(dimethylamino)propyl]-6,7,8,9,10,} {11-hexahydro-5h-cyclooct[b]indole}
3-(6,7,8,9,10,11-hexahydrocycloocta[b]indol-5-yl)-n,n-dimethyl-propan-1-amine
3-(6,7,8,9,10,11-hexahydro-5h-cycloocta[b]indol-5-yl)-n,n-dimethyl-1-propanamine
{5h-cyclooct[b]indole-5-propanamine,} 6,7,8,9,10,11-hexahydro-n, n-dimethyl-
n-(3-(6,7,8,9,10,11-hexahydro-5h-cycloocta[b]indol-5-yl)propyl)-n,n-dimethylamine
{5h-cyclooct[b]indole-5-propanamine,} 6,7,8,9,10, 11,hexahydro-n,n-dimethyl-
{5h-cyclooct[b]indole,} 6,7,8,9,10, 11-hexahydro-5-(3-dimethylaminopropyl)-
iprindole (usan/inn)
D04605
PDSP2_001594
OPREA1_812073
CHEBI:135177
L001038
CHEMBL126224
3-(6,7,8,9,10,11-hexahydrocycloocta[b]indol-5-yl)-n,n-dimethylpropan-1-amine
cas_5560-72-5
nsc_21722
bdbm81448
iprindol
69u0ikr8fp ,
iprindole [usan:inn:ban]
iprindolum
unii-69u0ikr8fp
iprindole [inn]
iprindole [usan]
iprindole [who-dd]
5-[3-(dimethylamino)propyl]-6,7,8,9,10,11-hexahydro-5h-cyclooct[b]indole
iprindole [mi]
SCHEMBL49509
5h-cyclooct(b)indole, 6,7,8,9,10,11-hexahydro-5-(3-dimethylaminopropyl)-
PLIGPBGDXASWPX-UHFFFAOYSA-N
n-[3-(6,7,8,9,10,11-hexahydro-5h-cycloocta[b]indol-5-yl)propyl]-n,n-dimethylamine #
DTXSID80204145
CS-0011246
HY-12392
DB13496
Q904673
chloraminettrihydrate
5h-cyclooct[b]indole, 5-[3-(dimethylamino)propyl]-6,7,8,9,10,11-hexahydro- (8ci); 5-[3-(dimethylamino)propyl]-6,7,8,9,10,11-hexahydro-5h-cyclooct[b]indole; nsc 169449; pramindole; tertran
MS-24057
(3-{5h,6h,7h,8h,9h,10h,11h-cycloocta[b]indol-5-yl}propyl)dimethylamine
AKOS040755577

Research Excerpts

Overview

ExcerptReference
"Iprindole is a relatively weak inhibitor of both norepinephrine (NE) and serotonin, whereas mianserin possesses at least modest potency as an inhibitor of NE uptake."( Goodwin, FK; Zis, AP, 1979)

Treatment

ExcerptReference
"Iprindole pretreatment increased drug levels in brain and prolonged the half-lives by two- to threefold."( Baker, JC; Fuller, RW; Molloy, BB, 1977)
"Rats treated with iprindole (IPR) (10 mg/kg, i.p.) were given a single dose (15 mg/kg, i.p.) of amphetamine (AMP). "( Gibb, JW; Peat, MA; Warren, PF, 1984)
"Pretreatment with iprindole led to an increase in brain and liver levels of fenfluramine, and, unexpectedly, to a marked decrease in levels of norfenfluramine in these tissues."( Baker, GB; Coutts, RT; Dewhurst, WG; Hegadoren, KM, 1991)

Drug Classes (1)

ClassDescription
indolesAny compound containing an indole skeleton.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Bioassays (24)

Assay IDTitleYearJournalArticle
AID1079939Cirrhosis, proven histopathologically. Value is number of references indexed. [column 'CIRRH' in source]
AID588220Literature-mined public compounds from Kruhlak et al phospholipidosis modelling dataset2008Toxicology mechanisms and methods, , Volume: 18, Issue:2-3
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
AID1079946Presence of at least one case with successful reintroduction. [column 'REINT' in source]
AID1079936Choleostatic liver toxicity, either proven histopathologically or where the ratio of maximal ALT or AST activity above normal to that of Alkaline Phosphatase is < 2 (see ACUTE). Value is number of references indexed. [column 'CHOLE' in source]
AID1079948Times to onset, minimal and maximal, observed in the indexed observations. [column 'DELAI' in source]
AID1079949Proposed mechanism(s) of liver damage. [column 'MEC' in source]
AID1079938Chronic liver disease either proven histopathologically, or through a chonic elevation of serum amino-transferase activity after 6 months. Value is number of references indexed. [column 'CHRON' in source]
AID1079947Comments (NB not yet translated). [column 'COMMENTAIRES' in source]
AID1079941Liver damage due to vascular disease: peliosis hepatitis, hepatic veno-occlusive disease, Budd-Chiari syndrome. Value is number of references indexed. [column 'VASC' in source]
AID1079937Severe hepatitis, defined as possibly life-threatening liver failure or through clinical observations. Value is number of references indexed. [column 'MASS' in source]
AID588208Literature-mined public compounds from Lowe et al phospholipidosis modelling dataset2010Molecular pharmaceutics, Oct-04, Volume: 7, Issue:5
Predicting phospholipidosis using machine learning.
AID1079943Malignant tumor, proven histopathologically. Value is number of references indexed. [column 'T.MAL' in source]
AID1079934Highest frequency of acute liver toxicity observed during clinical trials, expressed as a percentage. [column '% AIGUE' in source]
AID540237Phospholipidosis-positive literature compound observed in rat
AID1079931Moderate liver toxicity, defined via clinical-chemistry results: ALT or AST serum activity 6 times the normal upper limit (N) or alkaline phosphatase serum activity of 1.7 N. Value is number of references indexed. [column 'BIOL' in source]
AID1079935Cytolytic liver toxicity, either proven histopathologically or where the ratio of maximal ALT or AST activity above normal to that of Alkaline Phosphatase is > 5 (see ACUTE). Value is number of references indexed. [column 'CYTOL' in source]
AID1079940Granulomatous liver disease, proven histopathologically. Value is number of references indexed. [column 'GRAN' in source]
AID1079932Highest frequency of moderate liver toxicity observed during clinical trials, expressed as a percentage. [column '% BIOL' in source]
AID1079933Acute liver toxicity defined via clinical observations and clear clinical-chemistry results: serum ALT or AST activity > 6 N or serum alkaline phosphatases activity > 1.7 N. This category includes cytolytic, choleostatic and mixed liver toxicity. Value is
AID205268Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex at 10 uM1985Journal of medicinal chemistry, Mar, Volume: 28, Issue:3
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
AID1079942Steatosis, proven histopathologically. Value is number of references indexed. [column 'STEAT' in source]
AID643383Induction of phospholipidosis in bovine corneal fibroblasts assessed as lamellar inclusion bodies after 72 hrs by light microscopy2012Journal of medicinal chemistry, Jan-12, Volume: 55, Issue:1
In silico assay for assessing phospholipidosis potential of small druglike molecules: training, validation, and refinement using several data sets.
AID1079944Benign tumor, proven histopathologically. Value is number of references indexed. [column 'T.BEN' in source]
AID1079945Animal toxicity known. [column 'TOXIC' in source]
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (176)

TimeframeStudies, This Drug (%)All Drugs %
pre-1990150 (85.23)18.7374
1990's22 (12.50)18.2507
2000's2 (1.14)29.6817
2010's2 (1.14)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials6 (3.23%)5.53%
Reviews5 (2.69%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other175 (94.09%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceDescriptionRelationhip StrengthStudiesTrialsClassesRoles
quinacrine[no description available]medium80acridines;
aromatic ether;
organochlorine compound;
tertiary amino compound		antimalarial;
EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor
gallopamil[no description available]medium10benzenes;
organic amino compound
4-aminopyridine[no description available]medium10aminopyridine;
aromatic amine		avicide;
orphan drug;
potassium channel blocker
phenytoin[no description available]medium10imidazolidine-2,4-dioneanticonvulsant;
drug allergen;
sodium channel blocker;
teratogenic agent
8-(4-sulfophenyl)theophylline[no description available]medium10
8-phenyltheophylline[no description available]medium10
theophylline[no description available]medium10dimethylxanthineadenosine receptor antagonist;
anti-asthmatic drug;
anti-inflammatory agent;
bronchodilator agent;
drug metabolite;
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor;
fungal metabolite;
human blood serum metabolite;
immunomodulator;
muscle relaxant;
vasodilator agent
amitriptyline[no description available]medium400carbotricyclic compound;
tertiary amine		adrenergic uptake inhibitor;
antidepressant;
environmental contaminant;
tropomyosin-related kinase B receptor agonist;
xenobiotic
anisindione[no description available]medium10aromatic ketone;
beta-diketone		anticoagulant;
vitamin K antagonist
baclofen[no description available]medium10amino acid zwitterion;
gamma-amino acid;
monocarboxylic acid;
monochlorobenzenes;
primary amino compound		central nervous system depressant;
GABA agonist;
muscle relaxant
benzocaine[no description available]medium10benzoate ester;
substituted aniline		allergen;
antipruritic drug;
sensitiser;
topical anaesthetic
bepridil[no description available]medium20pyrrolidines;
tertiary amine		anti-arrhythmia drug;
antihypertensive agent;
calcium channel blocker;
vasodilator agent
biperiden[no description available]medium10piperidines;
tertiary alcohol;
tertiary amino compound		antidote to sarin poisoning;
antidyskinesia agent;
antiparkinson drug;
muscarinic antagonist;
parasympatholytic
bupivacaine[no description available]medium10aromatic amide;
piperidinecarboxamide;
tertiary amino compound
buspirone[no description available]medium30azaspiro compound;
N-alkylpiperazine;
N-arylpiperazine;
organic heteropolycyclic compound;
piperidones;
pyrimidines		anxiolytic drug;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
sedative;
serotonergic agonist
butacaine[no description available]medium10benzoate ester
butamben[no description available]medium10amino acid ester;
benzoate ester;
primary amino compound;
substituted aniline		local anaesthetic
caffeine[no description available]medium50purine alkaloid;
trimethylxanthine		adenosine A2A receptor antagonist;
adenosine receptor antagonist;
adjuvant;
central nervous system stimulant;
diuretic;
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor;
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor;
environmental contaminant;
food additive;
fungal metabolite;
geroprotector;
human blood serum metabolite;
mouse metabolite;
mutagen;
plant metabolite;
psychotropic drug;
ryanodine receptor agonist;
xenobiotic
verapamil[no description available]medium10aromatic ether;
nitrile;
polyether;
tertiary amino compound
carbamazepine[no description available]medium40dibenzoazepine;
ureas		analgesic;
anticonvulsant;
antimanic drug;
drug allergen;
EC 3.5.1.98 (histone deacetylase) inhibitor;
environmental contaminant;
glutamate transporter activator;
mitogen;
non-narcotic analgesic;
sodium channel blocker;
xenobiotic
chlordiazepoxide[no description available]medium20benzodiazepine
chlorpheniramine[no description available]medium20monochlorobenzenes;
pyridines;
tertiary amino compound		anti-allergic agent;
antidepressant;
antipruritic drug;
H1-receptor antagonist;
histamine antagonist;
serotonin uptake inhibitor
chlorpromazine[no description available]medium180organochlorine compound;
phenothiazines;
tertiary amine		anticoronaviral agent;
antiemetic;
dopaminergic antagonist;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
phenothiazine antipsychotic drug
cimetidine[no description available]medium30aliphatic sulfide;
guanidines;
imidazoles;
nitrile		adjuvant;
analgesic;
anti-ulcer drug;
H2-receptor antagonist;
P450 inhibitor
clomipramine[no description available]medium220dibenzoazepineanticoronaviral agent;
antidepressant;
EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor;
serotonergic antagonist;
serotonergic drug;
serotonin uptake inhibitor
cyproheptadine[no description available]medium10piperidines;
tertiary amine		anti-allergic agent;
antipruritic drug;
gastrointestinal drug;
H1-receptor antagonist;
serotonergic antagonist
desipramine[no description available]medium420dibenzoazepine;
secondary amino compound		adrenergic uptake inhibitor;
alpha-adrenergic antagonist;
antidepressant;
cholinergic antagonist;
drug allergen;
EC 3.1.4.12 (sphingomyelin phosphodiesterase) inhibitor;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
H1-receptor antagonist;
serotonin uptake inhibitor
desipramine[no description available]medium421dibenzoazepine;
secondary amino compound		adrenergic uptake inhibitor;
alpha-adrenergic antagonist;
antidepressant;
cholinergic antagonist;
drug allergen;
EC 3.1.4.12 (sphingomyelin phosphodiesterase) inhibitor;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
H1-receptor antagonist;
serotonin uptake inhibitor
diazepam[no description available]medium501,4-benzodiazepinone;
organochlorine compound		anticonvulsant;
anxiolytic drug;
environmental contaminant;
sedative;
xenobiotic
diazoxide[no description available]medium10benzothiadiazine;
organochlorine compound;
sulfone		antihypertensive agent;
beta-adrenergic agonist;
bronchodilator agent;
cardiotonic drug;
diuretic;
K-ATP channel agonist;
sodium channel blocker;
sympathomimetic agent;
vasodilator agent
dibucaine[no description available]medium10aromatic ether;
monocarboxylic acid amide;
tertiary amino compound		topical anaesthetic
dicyclomine[no description available]medium10carboxylic ester;
tertiary amine		antispasmodic drug;
muscarinic antagonist;
parasympatholytic
diphenidol[no description available]medium20benzenes;
piperidines;
tertiary alcohol		antiemetic
dilazep[no description available]medium10benzoate ester;
diazepane;
diester;
methoxybenzenes		cardioprotective agent;
platelet aggregation inhibitor;
vasodilator agent
diphenhydramine[no description available]medium10ether;
tertiary amino compound		anti-allergic agent;
antidyskinesia agent;
antiemetic;
antiparkinson drug;
antipruritic drug;
antitussive;
H1-receptor antagonist;
local anaesthetic;
muscarinic antagonist;
oneirogen;
sedative
dipyridamole[no description available]medium10piperidines;
pyrimidopyrimidine;
tertiary amino compound;
tetrol		adenosine phosphodiesterase inhibitor;
EC 3.5.4.4 (adenosine deaminase) inhibitor;
platelet aggregation inhibitor;
vasodilator agent
doxepin[no description available]medium70dibenzooxepine;
tertiary amino compound		antidepressant
droperidol[no description available]medium10aromatic ketone;
benzimidazoles;
organofluorine compound		anaesthesia adjuvant;
antiemetic;
dopaminergic antagonist;
first generation antipsychotic
etazolate[no description available]medium10ethyl ester;
hydrazone;
pyrazolopyridine		alpha-secretase activator;
antidepressant;
antipsychotic agent;
anxiolytic drug;
GABA agent;
neuroprotective agent;
phosphodiesterase IV inhibitor
felodipine[no description available]medium10dichlorobenzene;
dihydropyridine;
ethyl ester;
methyl ester		anti-arrhythmia drug;
antihypertensive agent;
calcium channel blocker;
vasodilator agent
flufenamic acid[no description available]medium20aromatic amino acid;
organofluorine compound		antipyretic;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug
fluphenazine[no description available]medium10N-alkylpiperazine;
organofluorine compound;
phenothiazines		anticoronaviral agent;
dopaminergic antagonist;
phenothiazine antipsychotic drug
flumazenil[no description available]medium10ethyl ester;
imidazobenzodiazepine;
organofluorine compound		antidote to benzodiazepine poisoning;
GABA antagonist
haloperidol[no description available]medium70aromatic ketone;
hydroxypiperidine;
monochlorobenzenes;
organofluorine compound;
tertiary alcohol		antidyskinesia agent;
antiemetic;
dopaminergic antagonist;
first generation antipsychotic;
serotonergic antagonist
hydroxyzine[no description available]medium50hydroxyether;
monochlorobenzenes;
N-alkylpiperazine		anticoronaviral agent;
antipruritic drug;
anxiolytic drug;
dermatologic drug;
H1-receptor antagonist
lidocaine[no description available]medium30benzenes;
monocarboxylic acid amide;
tertiary amino compound		anti-arrhythmia drug;
drug allergen;
environmental contaminant;
local anaesthetic;
xenobiotic
ici 118551[no description available]medium10indanes
imipramine[no description available]medium520dibenzoazepineadrenergic uptake inhibitor;
antidepressant;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor
imipramine[no description available]medium524dibenzoazepineadrenergic uptake inhibitor;
antidepressant;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor
indomethacin[no description available]medium10aromatic ether;
indole-3-acetic acids;
monochlorobenzenes;
N-acylindole		analgesic;
drug metabolite;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
environmental contaminant;
gout suppressant;
non-steroidal anti-inflammatory drug;
xenobiotic metabolite;
xenobiotic
1-methyl-3-isobutylxanthine[no description available]medium103-isobutyl-1-methylxanthine
loperamide[no description available]medium10monocarboxylic acid amide;
monochlorobenzenes;
piperidines;
tertiary alcohol		anticoronaviral agent;
antidiarrhoeal drug;
mu-opioid receptor agonist
mepivacaine[no description available]medium10piperidinecarboxamidedrug allergen;
local anaesthetic
benzoic acid [2-methyl-2-(propylamino)propyl] ester[no description available]medium10benzoate ester
metoprolol[no description available]medium20aromatic ether;
propanolamine;
secondary alcohol;
secondary amino compound		antihypertensive agent;
beta-adrenergic antagonist;
environmental contaminant;
geroprotector;
xenobiotic
mianserin[no description available]medium290dibenzoazepineadrenergic uptake inhibitor;
alpha-adrenergic antagonist;
antidepressant;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
geroprotector;
H1-receptor antagonist;
histamine agonist;
sedative;
serotonergic antagonist
nifedipine[no description available]medium10C-nitro compound;
dihydropyridine;
methyl ester		calcium channel blocker;
human metabolite;
tocolytic agent;
vasodilator agent
nisoldipine[no description available]medium10C-nitro compound;
dicarboxylic acids and O-substituted derivatives;
diester;
dihydropyridine;
methyl ester
nitrendipine[no description available]medium20C-nitro compound;
dicarboxylic acids and O-substituted derivatives;
diester;
dihydropyridine;
ethyl ester;
methyl ester		antihypertensive agent;
calcium channel blocker;
geroprotector;
vasodilator agent
nortriptyline[no description available]medium100organic tricyclic compound;
secondary amine		adrenergic uptake inhibitor;
analgesic;
antidepressant;
antineoplastic agent;
apoptosis inducer;
drug metabolite
oxethazaine[no description available]medium10amino acid amide
benoxinate[no description available]medium10amino acid ester;
benzoate ester;
substituted aniline;
tertiary amino compound		drug allergen;
local anaesthetic;
topical anaesthetic
papaverine[no description available]medium10benzylisoquinoline alkaloid;
dimethoxybenzene;
isoquinolines		antispasmodic drug;
vasodilator agent
pentobarbital[no description available]medium20barbituratesGABAA receptor agonist
pheniramine[no description available]medium20pyridines;
tertiary amino compound
phenobarbital[no description available]medium50barbituratesanticonvulsant;
drug allergen;
excitatory amino acid antagonist;
sedative
phenoxybenzamine[no description available]medium30aromatic amine
practolol[no description available]medium10acetamides;
ethanolamines;
propanolamine;
secondary alcohol;
secondary amino compound		anti-arrhythmia drug;
beta-adrenergic antagonist
pramoxine[no description available]medium10aromatic ether;
morpholines		local anaesthetic
prazosin[no description available]medium40aromatic ether;
furans;
monocarboxylic acid amide;
piperazines;
quinazolines		alpha-adrenergic antagonist;
antihypertensive agent;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor
prilocaine[no description available]medium10amino acid amide;
monocarboxylic acid amide		anticonvulsant;
local anaesthetic
proadifen[no description available]medium10diarylmethane
procainamide[no description available]medium30benzamidesanti-arrhythmia drug;
platelet aggregation inhibitor;
sodium channel blocker
procaine[no description available]medium40benzoate ester;
substituted aniline;
tertiary amino compound		central nervous system depressant;
drug allergen;
local anaesthetic;
peripheral nervous system drug
promazine[no description available]medium60phenothiazines;
tertiary amine		antiemetic;
dopaminergic antagonist;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
H1-receptor antagonist;
muscarinic antagonist;
phenothiazine antipsychotic drug;
serotonergic antagonist
promethazine[no description available]medium30phenothiazines;
tertiary amine		anti-allergic agent;
anticoronaviral agent;
antiemetic;
antipruritic drug;
H1-receptor antagonist;
local anaesthetic;
sedative
proxymetacaine[no description available]medium10benzoate ester
protriptyline[no description available]medium40carbotricyclic compoundantidepressant
pyrilamine[no description available]medium20aromatic ether;
ethylenediamine derivative		H1-receptor antagonist
4-(3-butoxy-4-methoxybenzyl)-2-imidazolidinone[no description available]medium10methoxybenzenes
rolipram[no description available]medium10pyrrolidin-2-onesantidepressant;
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor
secobarbital[no description available]medium20barbituratesanaesthesia adjuvant;
GABA modulator;
sedative
sotalol[no description available]medium30ethanolamines;
secondary alcohol;
secondary amino compound;
sulfonamide		anti-arrhythmia drug;
beta-adrenergic antagonist;
environmental contaminant;
xenobiotic
spiperone[no description available]medium20aromatic ketone;
azaspiro compound;
organofluorine compound;
piperidines;
tertiary amino compound		alpha-adrenergic antagonist;
antipsychotic agent;
dopaminergic antagonist;
psychotropic drug;
serotonergic antagonist
tetracaine[no description available]medium10benzoate ester;
tertiary amino compound		local anaesthetic
thioridazine[no description available]medium60phenothiazines;
piperidines		alpha-adrenergic antagonist;
dopaminergic antagonist;
EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
first generation antipsychotic;
H1-receptor antagonist;
serotonergic antagonist
trazodone[no description available]medium50monochlorobenzenes;
N-alkylpiperazine;
N-arylpiperazine;
triazolopyridine		adrenergic antagonist;
antidepressant;
anxiolytic drug;
H1-receptor antagonist;
sedative;
serotonin uptake inhibitor
trequinsin[no description available]medium10pyridopyrimidine
trifluoperazine[no description available]medium50N-alkylpiperazine;
N-methylpiperazine;
organofluorine compound;
phenothiazines		antiemetic;
calmodulin antagonist;
dopaminergic antagonist;
EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor;
EC 5.3.3.5 (cholestenol Delta-isomerase) inhibitor;
phenothiazine antipsychotic drug
reserpine[no description available]medium60alkaloid ester;
methyl ester;
yohimban alkaloid		adrenergic uptake inhibitor;
antihypertensive agent;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
environmental contaminant;
first generation antipsychotic;
plant metabolite;
xenobiotic
phentolamine[no description available]medium40imidazoles;
phenols;
substituted aniline;
tertiary amino compound		alpha-adrenergic antagonist;
vasodilator agent
hexobendine[no description available]medium10trihydroxybenzoic acid
dichloroisoproterenol[no description available]medium10
tetraethylammonium chloride[no description available]medium10organic chloride salt;
quaternary ammonium salt		potassium channel blocker
tetrabenazine[no description available]medium10benzoquinolizine;
cyclic ketone;
tertiary amino compound
piperoxan[no description available]medium10
nifenalol[no description available]medium10C-nitro compound
brompheniramine[no description available]medium40organobromine compound;
pyridines		anti-allergic agent;
H1-receptor antagonist
propoxycaine[no description available]medium10benzoate ester
dimethisoquin[no description available]medium10isoquinolines
parethoxycaine[no description available]medium10benzoate ester
yohimbine[no description available]medium60methyl 17-hydroxy-20xi-yohimban-16-carboxylatealpha-adrenergic antagonist;
dopamine receptor D2 antagonist;
serotonergic antagonist
2-chloroadenosine[no description available]medium10purine nucleoside
prenylamine[no description available]medium30diarylmethane
bicuculline[no description available]medium10benzylisoquinoline alkaloid;
isoquinoline alkaloid;
isoquinolines		agrochemical;
central nervous system stimulant;
GABA-gated chloride channel antagonist;
GABAA receptor antagonist;
neurotoxin
hexylcaine[no description available]medium10benzoate ester
piperocaine[no description available]medium10benzoate ester
diperodon[no description available]medium10carbamate ester
cyclomethycaine[no description available]medium10benzoate ester
carcainium chloride[no description available]medium10
azacyclonol[no description available]medium10diarylmethane
butoxamine[no description available]medium10
dexpropranolol[no description available]medium10propranolol
carticaine[no description available]medium10thiophenecarboxylic acid
timolol[no description available]medium10timololanti-arrhythmia drug;
antiglaucoma drug;
antihypertensive agent;
beta-adrenergic antagonist
butaclamol[no description available]medium10organic heteropentacyclic compound
etidocaine[no description available]medium20amino acid amidelocal anaesthetic
diltiazem[no description available]medium105-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetateantihypertensive agent;
calcium channel blocker;
vasodilator agent
Arbaclofen[no description available]medium10organonitrogen compound;
organooxygen compound
colforsin[no description available]medium20acetate ester;
cyclic ketone;
labdane diterpenoid;
organic heterotricyclic compound;
tertiary alpha-hydroxy ketone;
triol		adenylate cyclase agonist;
anti-HIV agent;
antihypertensive agent;
plant metabolite;
platelet aggregation inhibitor;
protein kinase A agonist
opromazine[no description available]medium10phenothiazines
corynanthine[no description available]medium10yohimban alkaloid
phenylisopropyladenosine[no description available]medium10aromatic amine;
benzenes;
hydrocarbyladenosine;
purine nucleoside;
secondary amino compound		adenosine A1 receptor agonist;
neuroprotective agent
w 7[no description available]medium10
2-n-butyl-3-(dimethylamino)-5,6-methylenedioxyindene[no description available]medium10
rac 109[no description available]medium10
atropine[no description available]medium40
strychnine[no description available]medium20monoterpenoid indole alkaloid;
organic heteroheptacyclic compound		avicide;
cholinergic antagonist;
glycine receptor antagonist;
neurotransmitter agent;
rodenticide
quinidine[no description available]medium40cinchona alkaloidalpha-adrenergic antagonist;
anti-arrhythmia drug;
antimalarial;
drug allergen;
EC 1.14.13.181 (13-deoxydaunorubicin hydroxylase) inhibitor;
EC 3.6.3.44 (xenobiotic-transporting ATPase) inhibitor;
muscarinic antagonist;
P450 inhibitor;
potassium channel blocker;
sodium channel blocker
cocaine[no description available]medium60benzoate ester;
methyl ester;
tertiary amino compound;
tropane alkaloid		adrenergic uptake inhibitor;
central nervous system stimulant;
dopamine uptake inhibitor;
environmental contaminant;
local anaesthetic;
mouse metabolite;
plant metabolite;
serotonin uptake inhibitor;
sodium channel blocker;
sympathomimetic agent;
vasoconstrictor agent;
xenobiotic
diethylstilbestrol[no description available]medium10olefinic compound;
polyphenol		antifungal agent;
antineoplastic agent;
autophagy inducer;
calcium channel blocker;
carcinogenic agent;
EC 1.1.1.146 (11beta-hydroxysteroid dehydrogenase) inhibitor;
EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor;
endocrine disruptor;
xenoestrogen
rauwolscine[no description available]medium10methyl 17-hydroxy-20xi-yohimban-16-carboxylate
chlorprothixene[no description available]medium10chlorprothixene
flunarizine[no description available]medium10diarylmethane
thiothixene[no description available]medium20N-methylpiperazineanticoronaviral agent
cinnarizine[no description available]medium10diarylmethane;
N-alkylpiperazine;
olefinic compound		anti-allergic agent;
antiemetic;
calcium channel blocker;
geroprotector;
H1-receptor antagonist;
histamine antagonist;
muscarinic antagonist
quinine[no description available]medium10cinchona alkaloidantimalarial;
muscle relaxant;
non-narcotic analgesic
codeine[no description available]medium10morphinane alkaloid;
organic heteropentacyclic compound		antitussive;
drug allergen;
environmental contaminant;
opioid analgesic;
opioid receptor agonist;
prodrug;
xenobiotic
morphine[no description available]medium30morphinane alkaloid;
organic heteropentacyclic compound;
tertiary amino compound		anaesthetic;
drug allergen;
environmental contaminant;
geroprotector;
mu-opioid receptor agonist;
opioid analgesic;
plant metabolite;
vasodilator agent;
xenobiotic
levorphanol[no description available]medium10morphinane alkaloid
dextrorphan[no description available]medium10morphinane alkaloid
zimeldine[no description available]medium90styrenes
1-methyl-d-lysergic acid butanolamide[no description available]medium10ergot alkaloid;
monocarboxylic acid amide		serotonergic antagonist;
sympatholytic agent;
vasoconstrictor agent
scopolamine hydrobromide[no description available]medium10
bupropion[no description available]medium30aromatic ketone;
monochlorobenzenes;
secondary amino compound		antidepressant;
environmental contaminant;
xenobiotic
3-methylcholanthrene[no description available]medium20ortho- and peri-fused polycyclic arenearyl hydrocarbon receptor agonist;
carcinogenic agent
tacrine[no description available]medium20acridines;
aromatic amine		EC 3.1.1.7 (acetylcholinesterase) inhibitor
acetaminophen[no description available]medium30acetamides;
phenols		antipyretic;
cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor;
cyclooxygenase 3 inhibitor;
environmental contaminant;
ferroptosis inducer;
geroprotector;
hepatotoxic agent;
human blood serum metabolite;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
xenobiotic
amiodarone[no description available]medium401-benzofurans;
aromatic ketone;
organoiodine compound;
tertiary amino compound		cardiovascular drug
aspirin[no description available]medium20benzoic acids;
phenyl acetates;
salicylates		anticoagulant;
antipyretic;
cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor;
drug allergen;
EC 1.1.1.188 (prostaglandin-F synthase) inhibitor;
geroprotector;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
plant activator;
platelet aggregation inhibitor;
prostaglandin antagonist;
teratogenic agent
bicalutamide[no description available]medium20(trifluoromethyl)benzenes;
monocarboxylic acid amide;
monofluorobenzenes;
nitrile;
sulfone;
tertiary alcohol
chlorcyclizine[no description available]medium40diarylmethane
chloroquine[no description available]medium120aminoquinoline;
organochlorine compound;
secondary amino compound;
tertiary amino compound		anticoronaviral agent;
antimalarial;
antirheumatic drug;
autophagy inhibitor;
dermatologic drug
ciprofibrate[no description available]medium30cyclopropanes;
monocarboxylic acid;
organochlorine compound		antilipemic drug
citalopram[no description available]medium402-benzofurans;
cyclic ether;
nitrile;
organofluorine compound;
tertiary amino compound
clofibrate[no description available]medium20aromatic ether;
ethyl ester;
monochlorobenzenes		anticholesteremic drug;
antilipemic drug;
geroprotector;
PPARalpha agonist
deferoxamine[no description available]medium20acyclic desferrioxaminebacterial metabolite;
ferroptosis inhibitor;
iron chelator;
siderophore
diclofenac[no description available]medium20amino acid;
aromatic amine;
dichlorobenzene;
monocarboxylic acid;
secondary amino compound		antipyretic;
drug allergen;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
environmental contaminant;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
xenobiotic
diflunisal[no description available]medium20monohydroxybenzoic acid;
organofluorine compound		non-narcotic analgesic;
non-steroidal anti-inflammatory drug
donepezil[no description available]medium20aromatic ether;
indanones;
piperidines;
racemate		EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
nootropic agent
doxapram[no description available]medium20morpholines;
pyrrolidin-2-ones		central nervous system stimulant
ethyl loflazepate[no description available]medium30organic molecular entity
felbamate[no description available]medium20carbamate esteranticonvulsant;
neuroprotective agent
fenfluramine[no description available]medium60(trifluoromethyl)benzenes;
secondary amino compound		appetite depressant;
serotonergic agonist;
serotonin uptake inhibitor
fenofibrate[no description available]medium20aromatic ether;
chlorobenzophenone;
isopropyl ester;
monochlorobenzenes		antilipemic drug;
environmental contaminant;
geroprotector;
xenobiotic
fluoxetine[no description available]medium120(trifluoromethyl)benzenes;
aromatic ether;
secondary amino compound
flutamide[no description available]medium20(trifluoromethyl)benzenes;
monocarboxylic acid amide		androgen antagonist;
antineoplastic agent
gemfibrozil[no description available]medium30aromatic etherantilipemic drug
homochlorocyclizine[no description available]medium30diarylmethane
hydroxyurea[no description available]medium20one-carbon compound;
ureas		antimetabolite;
antimitotic;
antineoplastic agent;
DNA synthesis inhibitor;
EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor;
genotoxin;
immunomodulator;
radical scavenger;
teratogenic agent
ketoconazole[no description available]medium30dichlorobenzene;
dioxolane;
ether;
imidazoles;
N-acylpiperazine;
N-arylpiperazine
maprotiline[no description available]medium80anthracenes
meclizine[no description available]medium30diarylmethane
metformin[no description available]medium30guanidinesenvironmental contaminant;
geroprotector;
hypoglycemic agent;
xenobiotic
methadone[no description available]medium20benzenes;
diarylmethane;
ketone;
tertiary amino compound
methapyrilene[no description available]medium30ethylenediamine derivativeanti-allergic agent;
carcinogenic agent;
H1-receptor antagonist;
sedative
oxidopamine[no description available]medium30benzenetriol;
catecholamine;
primary amino compound		drug metabolite;
human metabolite;
neurotoxin
perhexiline[no description available]medium40piperidinescardiovascular drug
phenacetin[no description available]medium30acetamides;
aromatic ether		cyclooxygenase 3 inhibitor;
non-narcotic analgesic;
peripheral nervous system drug
suramin[no description available]medium30naphthalenesulfonic acid;
phenylureas;
secondary carboxamide		angiogenesis inhibitor;
antinematodal drug;
antineoplastic agent;
apoptosis inhibitor;
EC 2.7.11.13 (protein kinase C) inhibitor;
GABA antagonist;
GABA-gated chloride channel antagonist;
purinergic receptor P2 antagonist;
ryanodine receptor agonist;
trypanocidal drug
temozolomide[no description available]medium20imidazotetrazine;
monocarboxylic acid amide;
triazene derivative		alkylating agent;
antineoplastic agent;
prodrug
tilorone[no description available]medium40aromatic ether;
diether;
fluoren-9-ones;
tertiary amino compound		anti-inflammatory agent;
antineoplastic agent;
antiviral agent;
interferon inducer;
nicotinic acetylcholine receptor agonist
pirinixic acid[no description available]medium20aryl sulfide;
organochlorine compound;
pyrimidines
carbon tetrachloride[no description available]medium20chlorocarbon;
chloromethanes		hepatotoxic agent;
refrigerant
physostigmine[no description available]medium30carbamate ester;
indole alkaloid		antidote to curare poisoning;
EC 3.1.1.8 (cholinesterase) inhibitor;
miotic
ethinyl estradiol[no description available]medium3017-hydroxy steroid;
3-hydroxy steroid;
terminal acetylenic compound		xenoestrogen
colchicine[no description available]medium20alkaloid;
colchicine		anti-inflammatory agent;
gout suppressant;
mutagen
chloroform[no description available]medium20chloromethanes;
one-carbon compound		carcinogenic agent;
central nervous system drug;
inhalation anaesthetic;
non-polar solvent;
refrigerant
triparanol[no description available]medium60stilbenoidanticoronaviral agent
cyclizine[no description available]medium40N-alkylpiperazineantiemetic;
central nervous system depressant;
cholinergic antagonist;
H1-receptor antagonist;
local anaesthetic
hydrazine[no description available]medium30azane;
hydrazines		EC 4.3.1.10 (serine-sulfate ammonia-lyase) inhibitor
norchlorcyclizine[no description available]medium30
N-[(2-chlorophenyl)methyl]-1-[4-[[(2-chlorophenyl)methylamino]methyl]cyclohexyl]methanamine[no description available]medium30aromatic amine
cyproterone acetate[no description available]medium2020-oxo steroid;
3-oxo-Delta(4) steroid;
acetate ester;
chlorinated steroid;
steroid ester		androgen antagonist;
geroprotector;
progestin
chlorphentermine[no description available]medium200amphetamines
emetine[no description available]medium30isoquinoline alkaloid;
pyridoisoquinoline		antiamoebic agent;
anticoronaviral agent;
antiinfective agent;
antimalarial;
antineoplastic agent;
antiprotozoal drug;
antiviral agent;
autophagy inhibitor;
emetic;
expectorant;
plant metabolite;
protein synthesis inhibitor
1-naphthylisothiocyanate[no description available]medium20isothiocyanateinsecticide
erythromycin[no description available]medium40cyclic ketone;
erythromycin
paraquat[no description available]medium30organic cationgeroprotector;
herbicide
stavudine[no description available]medium20dihydrofuran;
nucleoside analogue;
organic molecular entity		antimetabolite;
antiviral agent;
EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor
clomacran[no description available]medium30acridines
ethionine[no description available]medium20S-ethylhomocysteineantimetabolite;
carcinogenic agent
indoramin[no description available]medium30tryptamines
amineptin[no description available]medium20amino acid;
carbocyclic fatty acid;
carbotricyclic compound;
secondary amino compound		antidepressant;
dopamine uptake inhibitor
zidovudine[no description available]medium30azide;
pyrimidine 2',3'-dideoxyribonucleoside		antimetabolite;
antiviral drug;
HIV-1 reverse transcriptase inhibitor
tobramycin[no description available]medium30amino cyclitol glycosideantibacterial agent;
antimicrobial agent;
toxin
etoposide[no description available]medium30beta-D-glucoside;
furonaphthodioxole;
organic heterotetracyclic compound		antineoplastic agent;
DNA synthesis inhibitor
amikacin[no description available]medium40alpha-D-glucoside;
amino cyclitol glycoside;
aminoglycoside;
carboxamide		antibacterial drug;
antimicrobial agent;
nephrotoxin
methyldopa[no description available]medium40L-tyrosine derivative;
non-proteinogenic L-alpha-amino acid		alpha-adrenergic agonist;
antihypertensive agent;
hapten;
peripheral nervous system drug;
sympatholytic agent
nonachlazine[no description available]medium20
zileuton[no description available]medium201-benzothiophenes;
ureas		anti-asthmatic drug;
EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor;
ferroptosis inhibitor;
leukotriene antagonist;
non-steroidal anti-inflammatory drug
hexestrol bis(diethylaminoethyl ether)[no description available]medium30stilbenoid
synthalin a[no description available]medium20guanidineshepatotoxic agent;
hypoglycemic agent;
nephrotoxin
disobutamide[no description available]medium30acetamides
2-(4'-methylpiperazino-1-methyl)-1,3-diazafluoranthene 1-oxide[no description available]medium30
methotrexate[no description available]medium20dicarboxylic acid;
monocarboxylic acid amide;
pteridines		abortifacient;
antimetabolite;
antineoplastic agent;
antirheumatic drug;
dermatologic drug;
DNA synthesis inhibitor;
EC 1.5.1.3 (dihydrofolate reductase) inhibitor;
immunosuppressive agent
glucosamine[no description available]medium20D-glucosamineEscherichia coli metabolite;
geroprotector;
mouse metabolite
abacavir[no description available]medium202,6-diaminopurinesantiviral drug;
drug allergen;
HIV-1 reverse transcriptase inhibitor
netilmicin[no description available]medium30
clindamycin[no description available]medium30
azaserine[no description available]medium20carboxylic ester;
diazo compound;
L-serine derivative;
non-proteinogenic L-alpha-amino acid		antifungal agent;
antimetabolite;
antimicrobial agent;
antineoplastic agent;
glutamine antagonist;
immunosuppressive agent;
metabolite
dibekacin[no description available]medium30kanamycinsantibacterial agent;
protein synthesis inhibitor
sulindac[no description available]medium20monocarboxylic acid;
organofluorine compound;
sulfoxide		analgesic;
antineoplastic agent;
antipyretic;
apoptosis inducer;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
prodrug;
tocolytic agent
thioacetamide[no description available]medium20thiocarboxamidehepatotoxic agent
tamoxifen[no description available]medium50stilbenoid;
tertiary amino compound		angiogenesis inhibitor;
antineoplastic agent;
bone density conservation agent;
EC 1.2.3.1 (aldehyde oxidase) inhibitor;
EC 2.7.11.13 (protein kinase C) inhibitor;
estrogen antagonist;
estrogen receptor antagonist;
estrogen receptor modulator
stilbamidine[no description available]medium30
ceftazidime[no description available]medium30cephalosporin;
oxime O-ether		antibacterial drug;
drug allergen;
EC 2.4.1.129 (peptidoglycan glycosyltransferase) inhibitor
famotidine[no description available]medium201,3-thiazoles;
guanidines;
sulfonamide		anti-ulcer drug;
H2-receptor antagonist;
P450 inhibitor
dantrolene[no description available]medium20
gentamicin sulfate[no description available]medium20
azacosterol[no description available]medium30
hypoglycin a[no description available]medium20L-alpha-amino acid
amodiaquine hydrochloride[no description available]medium30
valproate sodium[no description available]medium10organic sodium saltgeroprotector
chlortetracycline[no description available]medium30
piroxicam[no description available]medium20benzothiazine;
monocarboxylic acid amide;
pyridines		analgesic;
antirheumatic drug;
cyclooxygenase 1 inhibitor;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-steroidal anti-inflammatory drug
demeclocycline[no description available]medium20
rolitetracycline[no description available]medium20
rifampin[no description available]medium20cyclic ketal;
hydrazone;
N-iminopiperazine;
N-methylpiperazine;
rifamycins;
semisynthetic derivative;
zwitterion		angiogenesis inhibitor;
antiamoebic agent;
antineoplastic agent;
antitubercular agent;
DNA synthesis inhibitor;
EC 2.7.7.6 (RNA polymerase) inhibitor;
Escherichia coli metabolite;
geroprotector;
leprostatic drug;
neuroprotective agent;
pregnane X receptor agonist;
protein synthesis inhibitor
clozapine[no description available]medium50benzodiazepine;
N-arylpiperazine;
N-methylpiperazine;
organochlorine compound		adrenergic antagonist;
dopaminergic antagonist;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
environmental contaminant;
GABA antagonist;
histamine antagonist;
muscarinic antagonist;
second generation antipsychotic;
serotonergic antagonist;
xenobiotic
adenine[no description available]medium106-aminopurines;
purine nucleobase		Daphnia magna metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
benzyl alcohol[no description available]medium10benzyl alcoholsantioxidant;
fragrance;
metabolite;
solvent
betaine[no description available]medium10amino-acid betaine;
glycine derivative		fundamental metabolite
lactic acid[no description available]medium102-hydroxy monocarboxylic acidalgal metabolite;
Daphnia magna metabolite
glycine[no description available]medium10alpha-amino acid;
amino acid zwitterion;
proteinogenic amino acid;
serine family amino acid		EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor;
fundamental metabolite;
hepatoprotective agent;
micronutrient;
neurotransmitter;
NMDA receptor agonist;
nutraceutical
glycerol[no description available]medium10alditol;
triol		algal metabolite;
detergent;
Escherichia coli metabolite;
geroprotector;
human metabolite;
mouse metabolite;
osmolyte;
Saccharomyces cerevisiae metabolite;
solvent
alpha-glycerophosphoric acid[no description available]medium10glycerol monophosphatealgal metabolite;
human metabolite
histamine[no description available]medium30aralkylamino compound;
imidazoles		human metabolite;
mouse metabolite;
neurotransmitter
inositol[no description available]medium10cyclitol;
hexol
niacin[no description available]medium10pyridine alkaloid;
pyridinemonocarboxylic acid;
vitamin B3		antidote;
antilipemic drug;
EC 3.5.1.19 (nicotinamidase) inhibitor;
Escherichia coli metabolite;
human urinary metabolite;
metabolite;
mouse metabolite;
plant metabolite;
vasodilator agent
succinic acid[no description available]medium10alpha,omega-dicarboxylic acid;
C4-dicarboxylic acid		anti-ulcer drug;
fundamental metabolite;
micronutrient;
nutraceutical;
radiation protective agent
methacholine[no description available]medium10acetate ester;
quaternary ammonium ion		bronchoconstrictor agent;
cholinergic agonist;
epitope;
muscarinic agonist;
vasodilator agent
albendazole[no description available]medium10aryl sulfide;
benzimidazoles;
benzimidazolylcarbamate fungicide;
carbamate ester		anthelminthic drug;
microtubule-destabilising agent;
tubulin modulator
amantadine[no description available]medium20adamantanes;
primary aliphatic amine		analgesic;
antiparkinson drug;
antiviral drug;
dopaminergic agent;
NMDA receptor antagonist;
non-narcotic analgesic
ambroxol[no description available]medium20aromatic amine
aminoglutethimide[no description available]medium10dicarboximide;
piperidones;
substituted aniline		adrenergic agent;
anticonvulsant;
antineoplastic agent;
EC 1.14.14.14 (aromatase) inhibitor
antazoline[no description available]medium10aromatic amine;
imidazolines;
tertiary amino compound		cholinergic antagonist;
H1-receptor antagonist;
xenobiotic
barbital[no description available]medium10barbituratesdrug allergen
bendroflumethiazide[no description available]medium10benzothiadiazine;
sulfonamide		antihypertensive agent;
diuretic
benzamide[no description available]medium20benzamides
benzquinamide[no description available]medium10monocarboxylic acid amideantiemetic;
antipsychotic agent;
H1-receptor antagonist;
muscarinic antagonist;
sedative
bethanidine[no description available]medium10guanidinesadrenergic antagonist;
antihypertensive agent
betaxolol[no description available]medium10propanolamineantihypertensive agent;
beta-adrenergic antagonist;
sympatholytic agent
bisacodyl[no description available]medium10diarylmethane
bromhexine[no description available]medium20organobromine compound;
substituted aniline;
tertiary amino compound		mucolytic
bunitrolol[no description available]medium10aromatic ether
bupranolol[no description available]medium10aromatic ether
butalbital[no description available]medium10barbituratesanalgesic;
sedative
metrizoate[no description available]medium10monocarboxylic acidradioopaque medium
carbazochrome[no description available]medium10
carbinoxamine[no description available]medium10monochlorobenzenes;
pyridines;
tertiary amino compound		anti-allergic agent;
antiparkinson drug;
H1-receptor antagonist;
muscarinic antagonist
carmustine[no description available]medium10N-nitrosoureas;
organochlorine compound		alkylating agent;
antineoplastic agent
chlorothiazide[no description available]medium10benzothiadiazineantihypertensive agent;
diuretic
chloroxine[no description available]medium10monohydroxyquinoline;
organochlorine compound		antibacterial agent;
antifungal drug;
antiseborrheic
chlorpropamide[no description available]medium10monochlorobenzenes;
N-sulfonylurea		hypoglycemic agent;
insulin secretagogue
clioquinol[no description available]medium10monohydroxyquinoline;
organochlorine compound;
organoiodine compound		antibacterial agent;
antifungal agent;
antimicrobial agent;
antineoplastic agent;
antiprotozoal drug;
chelator;
copper chelator
clofazimine[no description available]medium10monochlorobenzenes;
phenazines		dye;
leprostatic drug;
non-steroidal anti-inflammatory drug
clonidine[no description available]medium50clonidine;
imidazoline
cyclandelate[no description available]medium10carboxylic ester;
secondary alcohol		vasodilator agent
cyclofenil[no description available]medium10organic molecular entity
debrisoquin[no description available]medium10carboxamidine;
isoquinolines		adrenergic agent;
antihypertensive agent;
human metabolite;
sympatholytic agent
amphetamine[no description available]medium150primary amine
dichlorphenamide[no description available]medium10dichlorobenzene;
sulfonamide		antiglaucoma drug;
EC 4.2.1.1 (carbonic anhydrase) inhibitor;
ophthalmology drug
disopyramide[no description available]medium10monocarboxylic acid amide;
pyridines;
tertiary amino compound		anti-arrhythmia drug
valproic acid[no description available]medium30branched-chain fatty acid;
branched-chain saturated fatty acid		anticonvulsant;
antimanic drug;
EC 3.5.1.98 (histone deacetylase) inhibitor;
GABA agent;
neuroprotective agent;
psychotropic drug;
teratogenic agent
doxylamine[no description available]medium10pyridines;
tertiary amine		anti-allergic agent;
antiemetic;
antitussive;
cholinergic antagonist;
H1-receptor antagonist;
histamine antagonist;
sedative
dyphylline[no description available]medium10oxopurine;
propane-1,2-diols		bronchodilator agent;
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor;
muscle relaxant;
vasodilator agent
profenamine[no description available]medium10phenothiazines;
tertiary amino compound		adrenergic antagonist;
antidyskinesia agent;
antiparkinson drug;
histamine antagonist;
muscarinic antagonist
etizolam[no description available]medium10organic molecular entity
brl 42810[no description available]medium102-aminopurines;
acetate ester		antiviral drug;
prodrug
fenoprofen[no description available]medium10monocarboxylic acidantipyretic;
cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor;
drug allergen;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug
berotek[no description available]medium20resorcinols;
secondary alcohol;
secondary amino compound		beta-adrenergic agonist;
bronchodilator agent;
sympathomimetic agent;
tocolytic agent
flavoxate[no description available]medium10carboxylic ester;
flavones;
piperidines;
tertiary amino compound		antispasmodic drug;
muscarinic antagonist;
parasympatholytic
flecainide[no description available]medium20aromatic ether;
monocarboxylic acid amide;
organofluorine compound;
piperidines		anti-arrhythmia drug
flucytosine[no description available]medium10aminopyrimidine;
nucleoside analogue;
organofluorine compound;
pyrimidine antifungal drug;
pyrimidone		prodrug
fluorouracil[no description available]medium10nucleobase analogue;
organofluorine compound		antimetabolite;
antineoplastic agent;
environmental contaminant;
immunosuppressive agent;
radiosensitizing agent;
xenobiotic
fluphenazine depot[no description available]medium10decanoate ester;
N-alkylpiperazine;
organofluorine compound;
phenothiazines		dopaminergic antagonist;
phenothiazine antipsychotic drug;
prodrug
fluphenazine enanthate[no description available]medium10phenothiazines
flurazepam[no description available]medium101,4-benzodiazepinone;
monofluorobenzenes;
organochlorine compound;
tertiary amino compound		anticonvulsant;
anxiolytic drug;
GABAA receptor agonist;
sedative
flutazolam[no description available]medium10hemiaminal ether;
organic molecular entity
furosemide[no description available]medium20chlorobenzoic acid;
furans;
sulfonamide		environmental contaminant;
loop diuretic;
xenobiotic
gliclazide[no description available]medium10N-sulfonylureahypoglycemic agent;
insulin secretagogue;
radical scavenger
guanethidine[no description available]medium20azocanes;
guanidines		adrenergic antagonist;
antihypertensive agent;
sympatholytic agent
hexylresorcinol[no description available]medium10resorcinols
hydralazine[no description available]medium10azaarene;
hydrazines;
ortho-fused heteroarene;
phthalazines		antihypertensive agent;
vasodilator agent
hydroflumethiazide[no description available]medium10benzothiadiazine;
thiazide		antihypertensive agent;
diuretic
amrinone[no description available]medium10bipyridinesEC 3.1.4.* (phosphoric diester hydrolase) inhibitor
iodamide[no description available]medium10benzoic acids;
organoiodine compound		radioopaque medium
iothalamic acid[no description available]medium10organic molecular entity
iodipamide[no description available]medium10benzoic acids;
organoiodine compound;
secondary carboxamide		radioopaque medium
isoniazid[no description available]medium10carbohydrazideantitubercular agent;
drug allergen
isopropamide iodide[no description available]medium10diarylmethane
isoxsuprine[no description available]medium10alkylbenzene
ketotifen[no description available]medium10cyclic ketone;
olefinic compound;
organic heterotricyclic compound;
organosulfur heterocyclic compound;
piperidines;
tertiary amino compound		anti-asthmatic drug;
H1-receptor antagonist
labetalol[no description available]medium20benzamides;
benzenes;
phenols;
primary carboxamide;
salicylamides;
secondary alcohol;
secondary amino compound
leflunomide[no description available]medium10(trifluoromethyl)benzenes;
isoxazoles;
monocarboxylic acid amide		antineoplastic agent;
antiparasitic agent;
EC 1.3.98.1 [dihydroorotate oxidase (fumarate)] inhibitor;
EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor;
hepatotoxic agent;
immunosuppressive agent;
non-steroidal anti-inflammatory drug;
prodrug;
pyrimidine synthesis inhibitor;
tyrosine kinase inhibitor
loratadine[no description available]medium20benzocycloheptapyridine;
ethyl ester;
N-acylpiperidine;
organochlorine compound;
tertiary carboxamide		anti-allergic agent;
cholinergic antagonist;
geroprotector;
H1-receptor antagonist
lorazepam[no description available]medium10benzodiazepine
loxapine[no description available]medium10dibenzooxazepineantipsychotic agent;
dopaminergic antagonist
memantine[no description available]medium20adamantanes;
primary aliphatic amine		antidepressant;
antiparkinson drug;
dopaminergic agent;
neuroprotective agent;
NMDA receptor antagonist
vitamin k 3[no description available]medium201,4-naphthoquinones;
vitamin K		angiogenesis inhibitor;
antineoplastic agent;
EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor;
human urinary metabolite;
nutraceutical
mesoridazine[no description available]medium20phenothiazines;
sulfoxide;
tertiary amino compound		dopaminergic antagonist;
first generation antipsychotic
methocarbamol[no description available]medium10aromatic ether;
carbamate ester;
secondary alcohol
methyprylon[no description available]medium10organic molecular entity
metronidazole[no description available]medium10C-nitro compound;
imidazoles;
primary alcohol		antiamoebic agent;
antibacterial drug;
antimicrobial agent;
antiparasitic agent;
antitrichomonal drug;
environmental contaminant;
prodrug;
radiosensitizing agent;
xenobiotic
metyrapone[no description available]medium10aromatic ketoneantimetabolite;
diagnostic agent;
EC 1.14.15.4 (steroid 11beta-monooxygenase) inhibitor
midazolam[no description available]medium10imidazobenzodiazepine;
monofluorobenzenes;
organochlorine compound		anticonvulsant;
antineoplastic agent;
anxiolytic drug;
apoptosis inducer;
central nervous system depressant;
GABAA receptor agonist;
general anaesthetic;
muscle relaxant;
sedative
modafinil[no description available]medium10monocarboxylic acid amide;
sulfoxide
moxisylyte[no description available]medium10monoterpenoid
nalidixic acid[no description available]medium401,8-naphthyridine derivative;
monocarboxylic acid;
quinolone antibiotic		antibacterial drug;
antimicrobial agent;
DNA synthesis inhibitor
nefazodone[no description available]medium10aromatic ether;
monochlorobenzenes;
N-alkylpiperazine;
N-arylpiperazine;
triazoles		alpha-adrenergic antagonist;
analgesic;
antidepressant;
serotonergic antagonist;
serotonin uptake inhibitor
nimetazepam[no description available]medium101,4-benzodiazepinone;
C-nitro compound		anticonvulsant;
antispasmodic drug;
GABA modulator;
sedative
nimodipine[no description available]medium102-methoxyethyl ester;
C-nitro compound;
dicarboxylic acids and O-substituted derivatives;
diester;
dihydropyridine;
isopropyl ester		antihypertensive agent;
calcium channel blocker;
cardiovascular drug;
vasodilator agent
nitrazepam[no description available]medium101,4-benzodiazepinone;
C-nitro compound		anticonvulsant;
antispasmodic drug;
drug metabolite;
GABA modulator;
sedative
nomifensine[no description available]medium60isoquinolinesdopamine uptake inhibitor
ofloxacin[no description available]medium203-oxo monocarboxylic acid;
N-arylpiperazine;
N-methylpiperazine;
organofluorine compound;
oxazinoquinoline
omeprazole[no description available]medium10aromatic ether;
benzimidazoles;
pyridines;
sulfoxide
oxamniquine[no description available]medium10aromatic primary alcohol;
C-nitro compound;
quinolines;
secondary amino compound
oxolinic acid[no description available]medium10aromatic carboxylic acid;
organic heterotricyclic compound;
oxacycle;
quinolinemonocarboxylic acid;
quinolone antibiotic		antibacterial drug;
antifungal agent;
antiinfective agent;
antimicrobial agent;
enzyme inhibitor
pargyline[no description available]medium100aromatic amine
pentoxifylline[no description available]medium10oxopurine
perphenazine[no description available]medium20N-(2-hydroxyethyl)piperazine;
N-alkylpiperazine;
organochlorine compound;
phenothiazines		antiemetic;
dopaminergic antagonist;
phenothiazine antipsychotic drug
phenacemide[no description available]medium10acetamides
phenazopyridine[no description available]medium10diaminopyridine;
monoazo compound		anticoronaviral agent;
carcinogenic agent;
local anaesthetic;
non-narcotic analgesic
phenindione[no description available]medium10aromatic ketone;
beta-diketone		anticoagulant
phenolphthalein[no description available]medium10phenols
phentermine[no description available]medium110primary amineadrenergic agent;
appetite depressant;
central nervous system drug;
central nervous system stimulant;
dopaminergic agent;
sympathomimetic agent
pindolol[no description available]high20indoles;
secondary amine		antiglaucoma drug;
antihypertensive agent;
beta-adrenergic antagonist;
serotonergic antagonist;
vasodilator agent
pyranoprofen[no description available]medium10pyridochromene
probenecid[no description available]medium10benzoic acids;
sulfonamide		uricosuric drug
proglumide[no description available]medium10benzamides;
dicarboxylic acid monoamide;
glutamine derivative;
racemate		anti-ulcer drug;
cholecystokinin antagonist;
cholinergic antagonist;
delta-opioid receptor agonist;
drug metabolite;
gastrointestinal drug;
opioid analgesic;
xenobiotic metabolite
propiomazine[no description available]medium10aromatic ketone;
phenothiazines;
tertiary amino compound		dopaminergic antagonist;
histamine antagonist;
muscarinic antagonist;
phenothiazine antipsychotic drug;
sedative;
serotonergic antagonist
propranolol[no description available]medium80naphthalenes;
propanolamine;
secondary amine		anti-arrhythmia drug;
antihypertensive agent;
anxiolytic drug;
beta-adrenergic antagonist;
environmental contaminant;
human blood serum metabolite;
vasodilator agent;
xenobiotic
proxyphylline[no description available]medium10oxopurine
rizatriptan[no description available]medium10tryptaminesanti-inflammatory drug;
serotonergic agonist;
vasoconstrictor agent
rofecoxib[no description available]medium10butenolide;
sulfone		analgesic;
cyclooxygenase 2 inhibitor;
non-steroidal anti-inflammatory drug
salicylsalicylic acid[no description available]medium10benzoate ester;
benzoic acids;
phenols;
salicylates		antineoplastic agent;
antirheumatic drug;
EC 3.5.2.6 (beta-lactamase) inhibitor;
hypoglycemic agent;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
prodrug
ipodate[no description available]medium10
succinylcholine[no description available]medium10quaternary ammonium ion;
succinate ester		drug allergen;
muscle relaxant;
neuromuscular agent
sulfadimethoxine[no description available]medium10aromatic ether;
pyrimidines;
substituted aniline;
sulfonamide antibiotic;
sulfonamide		antiinfective agent;
antimicrobial agent;
drug allergen;
environmental contaminant;
xenobiotic
sulfamethoxazole[no description available]medium20isoxazoles;
substituted aniline;
sulfonamide antibiotic;
sulfonamide		antibacterial agent;
antiinfective agent;
antimicrobial agent;
drug allergen;
EC 1.1.1.153 [sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)] inhibitor;
EC 2.5.1.15 (dihydropteroate synthase) inhibitor;
environmental contaminant;
epitope;
P450 inhibitor;
xenobiotic
sulfobromophthalein[no description available]medium102-benzofurans;
organobromine compound;
organosulfonic acid;
phenols		dye
sumatriptan[no description available]medium20sulfonamide;
tryptamines		serotonergic agonist;
vasoconstrictor agent
terazosin[no description available]medium10furans;
piperazines;
primary amino compound;
quinazolines		alpha-adrenergic antagonist;
antihypertensive agent;
antineoplastic agent
terbutaline[no description available]medium10phenylethanolamines;
resorcinols		anti-asthmatic drug;
beta-adrenergic agonist;
bronchodilator agent;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
hypoglycemic agent;
sympathomimetic agent;
tocolytic agent
thalidomide[no description available]medium10phthalimides;
piperidones
tiaramide[no description available]medium10benzothiazoles
ticlopidine[no description available]medium10monochlorobenzenes;
thienopyridine		anticoagulant;
fibrin modulating drug;
hematologic agent;
P2Y12 receptor antagonist;
platelet aggregation inhibitor
tiopronin[no description available]medium10N-acyl-amino acid
tizanidine[no description available]medium10benzothiadiazole;
imidazoles		alpha-adrenergic agonist;
muscle relaxant
tolperisone[no description available]medium10aromatic ketone
ultram[no description available]medium10aromatic ether;
tertiary alcohol;
tertiary amino compound
trichlormethiazide[no description available]medium10benzothiadiazine;
sulfonamide antibiotic		antihypertensive agent;
diuretic
trifluperidol[no description available]medium10aromatic ketone
trimebutine[no description available]medium10trihydroxybenzoic acid
trimethadione[no description available]medium10oxazolidinoneanticonvulsant;
geroprotector
trimethoprim[no description available]medium10aminopyrimidine;
methoxybenzenes		antibacterial drug;
diuretic;
drug allergen;
EC 1.5.1.3 (dihydrofolate reductase) inhibitor;
environmental contaminant;
xenobiotic
trimipramine[no description available]medium30dibenzoazepine;
tertiary amino compound		antidepressant;
environmental contaminant;
xenobiotic
tripelennamine[no description available]medium20aromatic amine
troglitazone[no description available]medium10chromanes;
thiazolidinone		anticoagulant;
anticonvulsant;
antineoplastic agent;
antioxidant;
EC 6.2.1.3 (long-chain-fatty-acid--CoA ligase) inhibitor;
ferroptosis inhibitor;
hypoglycemic agent;
platelet aggregation inhibitor;
vasodilator agent
delavirdine[no description available]medium10aminopyridine;
indolecarboxamide;
N-acylpiperazine;
sulfonamide		antiviral drug;
HIV-1 reverse transcriptase inhibitor
venlafaxine[no description available]medium10cyclohexanols;
monomethoxybenzene;
tertiary alcohol;
tertiary amino compound		adrenergic uptake inhibitor;
analgesic;
antidepressant;
dopamine uptake inhibitor;
environmental contaminant;
serotonin uptake inhibitor;
xenobiotic
lysergic acid diethylamide[no description available]medium20ergoline alkaloid;
monocarboxylic acid amide;
organic heterotetracyclic compound		dopamine agonist;
hallucinogen;
serotonergic agonist
sorbitol[no description available]medium10glucitolcathartic;
Escherichia coli metabolite;
food humectant;
human metabolite;
laxative;
metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite;
sweetening agent
floxuridine[no description available]medium10nucleoside analogue;
organofluorine compound;
pyrimidine 2'-deoxyribonucleoside		antimetabolite;
antineoplastic agent;
antiviral drug;
radiosensitizing agent
norethindrone acetate[no description available]medium103-oxo-Delta(4) steroid;
acetate ester;
terminal acetylenic compound		progestin;
synthetic oral contraceptive
cyclobarbital[no description available]medium10barbiturates
norethandrolone[no description available]medium10corticosteroid hormone
oxandrolone[no description available]medium1017beta-hydroxy steroid;
3-oxo steroid;
anabolic androgenic steroid;
oxa-steroid		anabolic agent;
androgen
pilocarpine[no description available]medium10pilocarpineantiglaucoma drug
desoxycorticosterone acetate[no description available]medium10corticosteroid hormone
chloramphenicol[no description available]medium30C-nitro compound;
carboxamide;
diol;
organochlorine compound		antibacterial drug;
antimicrobial agent;
Escherichia coli metabolite;
geroprotector;
Mycoplasma genitalium metabolite;
protein synthesis inhibitor
lysine[no description available]medium10aspartate family amino acid;
L-alpha-amino acid zwitterion;
L-alpha-amino acid;
lysine;
organic molecular entity;
proteinogenic amino acid		algal metabolite;
anticonvulsant;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite
cysteamine[no description available]medium10amine;
thiol		geroprotector;
human metabolite;
mouse metabolite;
radiation protective agent
bretylium tosylate[no description available]medium10organosulfonate salt;
quaternary ammonium salt		adrenergic antagonist;
anti-arrhythmia drug;
antihypertensive agent
leucine[no description available]medium20amino acid zwitterion;
L-alpha-amino acid;
leucine;
proteinogenic amino acid;
pyruvate family amino acid		algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
gallamine triethiodide[no description available]medium10
cytarabine[no description available]medium10beta-D-arabinoside;
monosaccharide derivative;
pyrimidine nucleoside		antimetabolite;
antineoplastic agent;
antiviral agent;
immunosuppressive agent
4-hydroxypropiophenone[no description available]medium10acetophenones
methandrostenolone[no description available]medium10organic molecular entity
quinethazone[no description available]medium10quinazolinesantihypertensive agent;
diuretic
tribromoethanol[no description available]medium10alcohol;
organobromine compound
mepenzolate bromide[no description available]medium10diarylmethane
carbromal[no description available]medium10N-acylurea
pantothenic acid[no description available]medium10pantothenic acid;
vitamin B5		antidote to curare poisoning;
geroprotector;
human blood serum metabolite
buclizine[no description available]medium10monochlorobenzenes;
N-alkylpiperazine		antiemetic;
central nervous system depressant;
cholinergic antagonist;
histamine antagonist;
local anaesthetic
thiopropazate[no description available]medium10acetate ester;
N-alkylpiperazine;
organochlorine compound;
phenothiazines		dopaminergic antagonist;
phenothiazine antipsychotic drug
acetrizoic acid[no description available]medium10aminobenzoic acid
penicillin v[no description available]medium10penicillin allergen;
penicillin
pseudoephedrine[no description available]medium10phenylethanolamines;
secondary alcohol;
secondary amino compound		anti-asthmatic drug;
bronchodilator agent;
central nervous system drug;
nasal decongestant;
plant metabolite;
sympathomimetic agent;
vasoconstrictor agent;
xenobiotic
propylparaben[no description available]medium10benzoate ester;
paraben;
phenols		antifungal agent;
antimicrobial agent
methylparaben[no description available]medium10parabenantifungal agent;
antimicrobial food preservative;
neuroprotective agent;
plant metabolite
estradiol dipropionate[no description available]medium10steroid ester
paramethadione[no description available]medium10oxazolidinoneanticonvulsant
framycetin[no description available]medium10aminoglycosideallergen;
antibacterial drug;
Escherichia coli metabolite
anileridine[no description available]medium10ethyl ester;
piperidinecarboxylate ester;
substituted aniline		opioid analgesic;
opioid receptor agonist
ditiocarb[no description available]medium10dithiocarbamic acidschelator;
copper chelator
sulfalene[no description available]medium10pyrazines;
sulfonamide antibiotic;
sulfonamide
propantheline bromide[no description available]medium10xanthenes
ephedrine[no description available]medium10phenethylamine alkaloid;
phenylethanolamines		bacterial metabolite;
environmental contaminant;
nasal decongestant;
plant metabolite;
sympathomimetic agent;
vasoconstrictor agent;
xenobiotic
chlormadinone acetate[no description available]medium10corticosteroid hormone
evans blue[no description available]medium10organic sodium saltfluorochrome;
histological dye;
sodium channel blocker;
teratogenic agent
opipramol[no description available]medium40dibenzoazepine
carbutamide[no description available]medium10benzenes;
sulfonamide
glymidine[no description available]medium10diether;
pyrimidines;
sulfonamide		hypoglycemic agent
nandrolone[no description available]medium1017beta-hydroxy steroid;
3-oxo-Delta(4) steroid;
anabolic androgenic steroid		human metabolite
thiazolidine-4-carboxylic acid[no description available]medium10alpha-amino acid zwitterion;
non-proteinogenic alpha-amino acid;
sulfur-containing amino acid;
thiazolidinemonocarboxylic acid		antidote;
antioxidant;
hepatoprotective agent
dextropropoxyphene[no description available]medium101-benzyl-3-(dimethylamino)-2-methyl-1-phenylpropyl propanoatemu-opioid receptor agonist;
opioid analgesic
lucanthone[no description available]medium10thioxanthenesadjuvant;
antineoplastic agent;
EC 5.99.1.2 (DNA topoisomerase) inhibitor;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
mutagen;
photosensitizing agent;
prodrug;
schistosomicide drug
dichloralantipyrine[no description available]medium10
dihydralazine[no description available]medium10phthalazines
methallenestril[no description available]medium10naphthalenes
androstenediol[no description available]medium1017beta-hydroxy steroid;
3beta-hydroxy-Delta(5)-steroid		androgen;
human metabolite;
mouse metabolite;
radiation protective agent
levocarnitine[no description available]medium10carnitineantilipemic drug;
nootropic agent;
nutraceutical;
Saccharomyces cerevisiae metabolite;
water-soluble vitamin (role)
decamethonium dibromide[no description available]medium10
thiphenamil[no description available]medium10diarylmethane
metahexamide[no description available]medium10benzenes;
sulfonamide
phenindamine[no description available]medium10indene
2-amino-2-methyl-1-propanol[no description available]medium10
phendimetrazine[no description available]medium10
trimetozine[no description available]medium10morpholines
butaperazine[no description available]medium10phenothiazines
vinblastine[no description available]medium20
oxolamine[no description available]medium10oxadiazole;
ring assembly
ethylestrenol[no description available]medium1017beta-hydroxy steroid;
tertiary alcohol		anabolic agent
dehydroepiandrosterone acetate[no description available]medium10steroid ester
metaxalone[no description available]medium10aromatic ether
spectinomycin[no description available]medium20cyclic acetal;
cyclic hemiketal;
cyclic ketone;
pyranobenzodioxin;
secondary alcohol;
secondary amino compound		antibacterial drug;
antimicrobial agent;
bacterial metabolite
clothiapine[no description available]medium10dibenzothiazepine
azaribine[no description available]medium10acetate ester;
N-glycosyl-1,2,4-triazine		antipsoriatic;
prodrug
sulfadoxine[no description available]medium10pyrimidines;
sulfonamide		antibacterial drug;
antimalarial
acetophenazine[no description available]medium10N-(2-hydroxyethyl)piperazine;
N-alkylpiperazine;
phenothiazines		phenothiazine antipsychotic drug
cephaloglycin[no description available]medium10beta-lactam antibiotic allergen;
cephalosporin		antimicrobial agent
streptomycin[no description available]medium20antibiotic antifungal drug;
antibiotic fungicide;
streptomycins		antibacterial drug;
antifungal agrochemical;
antimicrobial agent;
antimicrobial drug;
bacterial metabolite;
protein synthesis inhibitor
noxiptilin[no description available]medium20organic tricyclic compound
benorilate[no description available]medium10carbonyl compound
metocurine[no description available]medium10isoquinolines
floxacillin[no description available]medium10penicillin allergen;
penicillin		antibacterial drug
isometheptene[no description available]medium10secondary amino compound
olsalazine[no description available]medium10azobenzenes;
dicarboxylic acid		non-steroidal anti-inflammatory drug;
prodrug
molindone[no description available]medium10indoles
hexocyclium[no description available]medium10amine
ancitabine[no description available]medium10diol;
organic heterotricyclic compound		antimetabolite;
antineoplastic agent;
prodrug
clortermine[no description available]medium10amphetamines
nicofuranose[no description available]medium10organooxygen compound
apazone[no description available]medium10benzotriazinesnon-steroidal anti-inflammatory drug;
uricosuric drug
cloforex[no description available]medium20amphetamines
selegiline[no description available]medium10selegiline;
terminal acetylenic compound		geroprotector
levamisole[no description available]medium106-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazoleantinematodal drug;
antirheumatic drug;
EC 3.1.3.1 (alkaline phosphatase) inhibitor;
immunological adjuvant;
immunomodulator
clobutinol[no description available]medium10benzenes;
organic amino compound
thiamphenicol[no description available]medium10monocarboxylic acid amide;
sulfone		antimicrobial agent;
immunosuppressive agent
isosorbide-5-mononitrate[no description available]medium10glucitol derivative;
nitrate ester		nitric oxide donor;
vasodilator agent
razoxane[no description available]medium10N-alkylpiperazine
fludarabine phosphate[no description available]medium10nucleoside analogue;
organofluorine compound;
purine arabinonucleoside monophosphate		antimetabolite;
antineoplastic agent;
antiviral agent;
DNA synthesis inhibitor;
immunosuppressive agent;
prodrug
proquazone[no description available]medium10pyrimidines
halazepam[no description available]medium10organic molecular entity
ripazepam[no description available]medium10benzenes
amoxicillin[no description available]medium10penicillin allergen;
penicillin		antibacterial drug
moricizine[no description available]medium20carbamate ester;
morpholines;
phenothiazines		anti-arrhythmia drug
feprazone[no description available]medium10organic molecular entity
halofantrine[no description available]medium10phenanthrenes
ribavirin[no description available]medium101-ribosyltriazole;
aromatic amide;
monocarboxylic acid amide;
primary carboxamide		anticoronaviral agent;
antiinfective agent;
antimetabolite;
antiviral agent;
EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor
epirubicin[no description available]medium10aminoglycoside;
anthracycline antibiotic;
anthracycline;
deoxy hexoside;
monosaccharide derivative;
p-quinones;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone		antimicrobial agent;
antineoplastic agent;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor
prenalterol[no description available]medium20aromatic ether
lorcainide[no description available]medium10acetamides
idarubicin[no description available]medium10anthracycline antibiotic;
deoxy hexoside;
monosaccharide derivative
atracurium[no description available]medium10diester;
quaternary ammonium ion		muscle relaxant;
nicotinic antagonist
pergolide[no description available]medium10diamine;
methyl sulfide;
organic heterotetracyclic compound		antiparkinson drug;
dopamine agonist
doxofylline[no description available]medium10oxopurineanti-asthmatic drug;
antitussive;
bronchodilator agent
alfentanil[no description available]medium10monocarboxylic acid amide;
piperidines		central nervous system depressant;
intravenous anaesthetic;
mu-opioid receptor agonist;
opioid analgesic;
peripheral nervous system drug
cefotetan[no description available]medium10
quinapril[no description available]medium10dicarboxylic acid monoester;
ethyl ester;
isoquinolines;
tertiary carboxamide		antihypertensive agent;
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor;
prodrug
esmolol[no description available]medium10aromatic ether;
ethanolamines;
methyl ester;
secondary alcohol;
secondary amino compound
tiagabine[no description available]medium10beta-amino acid;
piperidinemonocarboxylic acid;
tertiary amino compound;
thiophenes		anticonvulsant;
GABA reuptake inhibitor
lamivudine[no description available]medium10monothioacetal;
nucleoside analogue;
oxacycle;
primary alcohol		allergen;
anti-HBV agent;
antiviral drug;
EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor;
HIV-1 reverse transcriptase inhibitor;
prodrug
ziprasidone[no description available]medium101,2-benzisothiazole;
indolones;
organochlorine compound;
piperazines		antipsychotic agent;
dopaminergic antagonist;
histamine antagonist;
muscarinic antagonist;
psychotropic drug;
serotonergic antagonist
adenosine[no description available]medium20adenosines;
purines D-ribonucleoside		analgesic;
anti-arrhythmia drug;
fundamental metabolite;
human metabolite;
vasodilator agent
ceftezole[no description available]medium10cephalosporin;
thiadiazoles
sertraline[no description available]medium20dichlorobenzene;
secondary amino compound;
tetralins		antidepressant;
serotonin uptake inhibitor
dipropylacetamide[no description available]medium10fatty amidegeroprotector;
metabolite;
teratogenic agent
clociguanil[no description available]medium20
lividomycin[no description available]medium10lividomycinsmetabolite
gentamicin c1[no description available]medium20
clarithromycin[no description available]medium20macrolide antibioticantibacterial drug;
environmental contaminant;
protein synthesis inhibitor;
xenobiotic
moexipril[no description available]medium10peptide
sennoside B[no description available]medium10oxo dicarboxylic acid;
sennosides
dimethacrine[no description available]medium10acridines
perindopril[no description available]medium10alpha-amino acid ester;
dicarboxylic acid monoester;
ethyl ester;
organic heterobicyclic compound		antihypertensive agent;
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor
5-hydroxydopamine[no description available]medium20catecholamine
tazobactam[no description available]medium10penicillanic acids;
triazoles		antiinfective agent;
antimicrobial agent;
EC 3.5.2.6 (beta-lactamase) inhibitor
xylose[no description available]medium10D-xylose
levofloxacin[no description available]medium209-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid;
fluoroquinolone antibiotic;
quinolone antibiotic		antibacterial drug;
DNA synthesis inhibitor;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
topoisomerase IV inhibitor
clofibride[no description available]medium10monocarboxylic acid
aminopterin[no description available]medium10dicarboxylic acidEC 1.5.1.3 (dihydrofolate reductase) inhibitor;
mutagen
l 694,458[no description available]medium20
carbocysteine[no description available]medium10L-cysteine thioether;
non-proteinogenic L-alpha-amino acid		mucolytic
dromostanolone propionate[no description available]medium103-oxo-5alpha-steroid;
steroid ester		antineoplastic agent
phenethicillin[no description available]medium10penicillin allergen;
penicillin
bekanamycin[no description available]medium10kanamycins
griseofulvin[no description available]medium101-benzofurans;
antibiotic antifungal drug;
benzofuran antifungal drug;
organochlorine compound;
oxaspiro compound		antibacterial agent;
Penicillium metabolite
hetacillin[no description available]medium10penicillinantibacterial drug
medigoxin[no description available]medium10cardenolide glycoside
betamethasone acetate[no description available]medium1011beta-hydroxy steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
3-oxo-Delta(1),Delta(4)-steroid;
acetate ester;
fluorinated steroid;
steroid ester;
tertiary alpha-hydroxy ketone
retinol[no description available]medium10retinol;
vitamin A		human metabolite;
mouse metabolite;
plant metabolite
zithromax[no description available]medium20macrolide antibioticantibacterial drug;
environmental contaminant;
xenobiotic
melphalan[no description available]medium10L-phenylalanine derivative;
nitrogen mustard;
non-proteinogenic L-alpha-amino acid;
organochlorine compound		alkylating agent;
antineoplastic agent;
carcinogenic agent;
drug allergen;
immunosuppressive agent
riboflavin[no description available]medium10flavin;
vitamin B2		anti-inflammatory agent;
antioxidant;
cofactor;
Escherichia coli metabolite;
food colouring;
fundamental metabolite;
human urinary metabolite;
mouse metabolite;
photosensitizing agent;
plant metabolite
flavin mononucleotide[no description available]medium10flavin mononucleotide;
vitamin B2		bacterial metabolite;
coenzyme;
cofactor;
human metabolite;
mouse metabolite
mezlocillin[no description available]medium10penicillin allergen;
penicillin		antibacterial drug
mitobronitol[no description available]medium10alcohol;
organobromine compound
prednisolone hemisuccinate[no description available]medium1011beta-hydroxy steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
3-oxo-Delta(1),Delta(4)-steroid;
hemisuccinate;
tertiary alpha-hydroxy ketone		anti-inflammatory drug
octotropine methylbromide[no description available]medium10
nsc 4347[no description available]medium10
etomidate[no description available]medium10ethyl ester;
imidazoles		intravenous anaesthetic;
sedative
mercaptopurine[no description available]medium10aryl thiol;
purines;
thiocarbonyl compound		anticoronaviral agent;
antimetabolite;
antineoplastic agent
lobeline[no description available]medium10
benztropine[no description available]medium10diarylmethane
thiouracil[no description available]medium10nucleobase analogue;
thiocarbonyl compound		antithyroid drug;
metabolite
terbinafine[no description available]medium10acetylenic compound;
allylamine antifungal drug;
enyne;
naphthalenes;
tertiary amine		EC 1.14.13.132 (squalene monooxygenase) inhibitor;
P450 inhibitor;
sterol biosynthesis inhibitor
1,4-benzoquinone guanylhydrazone thiosemicarbazone[no description available]medium10
digoxin[no description available]medium10cardenolide glycoside;
steroid saponin		anti-arrhythmia drug;
cardiotonic drug;
EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor;
epitope
zeranol[no description available]medium10macrolide
thiopental[no description available]medium10barbituratesanticonvulsant;
drug allergen;
environmental contaminant;
intravenous anaesthetic;
sedative;
xenobiotic
toremifene[no description available]medium10aromatic ether;
organochlorine compound;
tertiary amine		antineoplastic agent;
bone density conservation agent;
estrogen antagonist;
estrogen receptor modulator
albutoin[no description available]medium10organonitrogen compound;
organooxygen compound
iodothiouracil[no description available]medium10organohalogen compound;
pyrimidines
tolcapone[no description available]medium102-nitrophenols;
benzophenones;
catechols		antiparkinson drug;
EC 2.1.1.6 (catechol O-methyltransferase) inhibitor
bilirubin[no description available]medium20biladienes;
dicarboxylic acid		antioxidant;
human metabolite;
mouse metabolite
dinoprost[no description available]medium10monocarboxylic acid;
prostaglandins Falpha		human metabolite;
mouse metabolite
calcitriol[no description available]medium10D3 vitamins;
hydroxycalciol;
triol		antineoplastic agent;
antipsoriatic;
bone density conservation agent;
calcium channel agonist;
calcium channel modulator;
hormone;
human metabolite;
immunomodulator;
metabolite;
mouse metabolite;
nutraceutical
beta carotene[no description available]medium10carotenoid beta-end derivative;
cyclic carotene		antioxidant;
biological pigment;
cofactor;
ferroptosis inhibitor;
human metabolite;
mouse metabolite;
plant metabolite;
provitamin A
clavulanic acid[no description available]medium10oxapenamantibacterial drug;
anxiolytic drug;
bacterial metabolite;
EC 3.5.2.6 (beta-lactamase) inhibitor
eprosartan[no description available]medium10dicarboxylic acid;
imidazoles;
thiophenes		angiotensin receptor antagonist;
antihypertensive agent;
environmental contaminant;
xenobiotic
ethchlorvynol[no description available]medium10
rokitamycin[no description available]medium10organic molecular entity
etretinate[no description available]medium10enoate ester;
ethyl ester;
retinoid		keratolytic drug
misoprostol[no description available]medium10
epoprostenol[no description available]medium10prostaglandins Imouse metabolite
triprolidine[no description available]medium10N-alkylpyrrolidine;
olefinic compound;
pyridines		H1-receptor antagonist
natamycin[no description available]medium10antibiotic antifungal drug;
dicarboxylic acid monoester;
epoxide;
macrolide antibiotic;
monosaccharide derivative;
polyene antibiotic		antifungal agrochemical;
antimicrobial food preservative;
apoptosis inducer;
bacterial metabolite;
ophthalmology drug
cloprednol[no description available]medium1021-hydroxy steroid
cyproterone[no description available]medium1017alpha-hydroxy steroid;
20-oxo steroid;
3-oxo-Delta(4) steroid;
chlorinated steroid;
tertiary alpha-hydroxy ketone		androgen antagonist
estropipate[no description available]medium10piperazinium salt;
steroid sulfate
hydroxystilbamidine[no description available]medium10
levetiracetam[no description available]medium10pyrrolidin-2-onesanticonvulsant;
environmental contaminant;
xenobiotic
meprednisone[no description available]medium1021-hydroxy steroid
oxymorphone[no description available]medium10morphinane alkaloid
acepreval[no description available]medium10corticosteroid hormone
proscillaridin[no description available]medium10organic molecular entity
fluvoxamine[no description available]medium20(trifluoromethyl)benzenes;
5-methoxyvalerophenone O-(2-aminoethyl)oxime		antidepressant;
anxiolytic drug;
serotonin uptake inhibitor
butorphanol[no description available]medium10morphinane alkaloidantitussive;
kappa-opioid receptor agonist;
mu-opioid receptor agonist;
opioid analgesic
cefixime[no description available]medium10cephalosporinantibacterial drug;
drug allergen
ceftriaxone[no description available]medium101,2,4-triazines;
1,3-thiazoles;
cephalosporin;
oxime O-ether		antibacterial drug;
drug allergen;
EC 3.5.2.6 (beta-lactamase) inhibitor
trandolapril[no description available]medium10dicarboxylic acid monoester;
dipeptide;
ethyl ester;
organic heterobicyclic compound;
secondary amino compound;
tertiary carboxamide		antihypertensive agent;
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor;
prodrug
nitrofurantoin[no description available]medium10imidazolidine-2,4-dione;
nitrofuran antibiotic;
organonitrogen heterocyclic antibiotic;
organooxygen heterocyclic antibiotic		antibacterial drug;
antiinfective agent;
hepatotoxic agent
fosinopril[no description available]medium10
abt-770[no description available]medium20
9-n-(1-propyl)erythromyclamine[no description available]medium20
homatropine methylbromide[no description available]medium10
vindesine[no description available]medium10
novobiocin[no description available]medium10carbamate ester;
ether;
hexoside;
hydroxycoumarin;
monocarboxylic acid amide;
monosaccharide derivative;
phenols		antibacterial agent;
antimicrobial agent;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
Escherichia coli metabolite;
hepatoprotective agent
tetracycline[no description available]medium20
warfarin[no description available]medium10benzenes;
hydroxycoumarin;
methyl ketone
bephenium hydroxynaphthoate[no description available]medium10
phenprocoumon[no description available]medium10hydroxycoumarinanticoagulant;
EC 1.6.5.2 [NAD(P)H dehydrogenase (quinone)] inhibitor
folic acid[no description available]medium10folic acids;
N-acyl-amino acid		human metabolite;
mouse metabolite;
nutrient
viomycin[no description available]medium10heterodetic cyclic peptide;
peptide antibiotic		antitubercular agent
dacarbazine[no description available]medium10dacarbazine
olanzapine[no description available]medium10benzodiazepine;
N-arylpiperazine;
N-methylpiperazine		antiemetic;
dopaminergic antagonist;
histamine antagonist;
muscarinic antagonist;
second generation antipsychotic;
serotonergic antagonist;
serotonin uptake inhibitor
allopurinol[no description available]medium20nucleobase analogue;
organic heterobicyclic compound		antimetabolite;
EC 1.17.3.2 (xanthine oxidase) inhibitor;
gout suppressant;
radical scavenger
trospectomycin[no description available]medium20dioxanes
bts 54 524[no description available]medium10
methoxyhydroxyphenylglycol[no description available]medium40methoxybenzenes;
phenols
s-adenosylmethionine[no description available]medium10organic cation;
sulfonium compound		coenzyme;
cofactor;
human metabolite;
micronutrient;
Mycoplasma genitalium metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite
carbachol[no description available]medium10ammonium salt;
carbamate ester		cardiotonic drug;
miotic;
muscarinic agonist;
nicotinic acetylcholine receptor agonist;
non-narcotic analgesic
sulpiride[no description available]medium10benzamides;
N-alkylpyrrolidine;
sulfonamide		antidepressant;
antiemetic;
antipsychotic agent;
dopaminergic antagonist
dextroamphetamine[no description available]medium1301-phenylpropan-2-amineadrenergic agent;
adrenergic uptake inhibitor;
dopamine uptake inhibitor;
dopaminergic agent;
neurotoxin;
sympathomimetic agent
alpha-methyl-m-tyrosine[no description available]medium10monocarboxylic acid
thiourea[no description available]medium10one-carbon compound;
thioureas;
ureas		antioxidant;
chromophore
dimaprit[no description available]medium10imidothiocarbamic ester
hydroxyindoleacetic acid[no description available]medium70indole-3-acetic acidsdrug metabolite;
human metabolite;
mouse metabolite
thyroxine[no description available]medium102-halophenol;
iodophenol;
L-phenylalanine derivative;
non-proteinogenic L-alpha-amino acid;
thyroxine zwitterion;
thyroxine		antithyroid drug;
human metabolite;
mouse metabolite;
thyroid hormone
methamphetamine[no description available]medium40amphetamines;
secondary amine		central nervous system stimulant;
environmental contaminant;
neurotoxin;
psychotropic drug;
xenobiotic
tryptophan[no description available]medium30erythrose 4-phosphate/phosphoenolpyruvate family amino acid;
L-alpha-amino acid zwitterion;
L-alpha-amino acid;
proteinogenic amino acid;
tryptophan zwitterion;
tryptophan		antidepressant;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite
lithium[no description available]medium61alkali metal atom
pyridoxine[no description available]medium10hydroxymethylpyridine;
methylpyridines;
monohydroxypyridine;
vitamin B6		cofactor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
orphenadrine[no description available]medium20ether;
tertiary amino compound		antidyskinesia agent;
antiparkinson drug;
H1-receptor antagonist;
muscarinic antagonist;
muscle relaxant;
NMDA receptor antagonist;
parasympatholytic
viloxazine[no description available]medium50aromatic ether
flupenthixol[no description available]medium10thioxanthenes
tofenacin[no description available]medium10diarylmethane
alprenolol[no description available]medium20secondary alcohol;
secondary amino compound		anti-arrhythmia drug;
antihypertensive agent;
beta-adrenergic antagonist;
sympatholytic agent
dihydroalprenolol[no description available]medium30
glucose, (beta-d)-isomer[no description available]medium10D-glucopyranoseepitope;
mouse metabolite
phenylephrine[no description available]medium20phenols;
phenylethanolamines;
secondary amino compound		alpha-adrenergic agonist;
cardiotonic drug;
mydriatic agent;
nasal decongestant;
protective agent;
sympathomimetic agent;
vasoconstrictor agent
ouabain[no description available]medium3011alpha-hydroxy steroid;
14beta-hydroxy steroid;
5beta-hydroxy steroid;
alpha-L-rhamnoside;
cardenolide glycoside;
steroid hormone		anti-arrhythmia drug;
cardiotonic drug;
EC 2.3.3.1 [citrate (Si)-synthase] inhibitor;
EC 3.1.3.41 (4-nitrophenylphosphatase) inhibitor;
EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor;
EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor;
ion transport inhibitor;
plant metabolite
neostigmine[no description available]medium10quaternary ammonium ionantidote to curare poisoning;
EC 3.1.1.7 (acetylcholinesterase) inhibitor
sulforidazine[no description available]medium10phenothiazines
melatonin[no description available]medium10acetamides;
tryptamines		anticonvulsant;
central nervous system depressant;
geroprotector;
hormone;
human metabolite;
immunological adjuvant;
mouse metabolite;
radical scavenger
n-acetylserotonin[no description available]medium10acetamides;
N-acylserotonin;
phenols		antioxidant;
human metabolite;
mouse metabolite;
tropomyosin-related kinase B receptor agonist
piperidines[no description available]medium20
ketanserin[no description available]medium20aromatic ketone;
organofluorine compound;
piperidines;
quinazolines		alpha-adrenergic antagonist;
antihypertensive agent;
cardiovascular drug;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
serotonergic antagonist
nisoxetine[no description available]medium20aromatic ether;
secondary amino compound		adrenergic uptake inhibitor;
antidepressant
corticosterone[no description available]medium2011beta-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(4) steroid;
C21-steroid;
glucocorticoid;
primary alpha-hydroxy ketone		human metabolite;
mouse metabolite
alpha-aminopyridine[no description available]medium10
org 6582[no description available]medium10
5-hydroxytryptophan[no description available]medium20hydroxytryptophanhuman metabolite;
neurotransmitter
methysergide[no description available]medium30ergoline alkaloid
nordefrin[no description available]medium10catecholamine
metaraminol[no description available]medium10phenylethanolaminesalpha-adrenergic agonist;
sympathomimetic agent;
vasoconstrictor agent
amfonelic acid[no description available]medium30
3,4-dihydroxyphenylacetic acid[no description available]medium50catechols;
dihydroxyphenylacetic acid		human metabolite
homovanillic acid[no description available]medium50guaiacols;
monocarboxylic acid		human metabolite;
mouse metabolite
apomorphine[no description available]medium30aporphine alkaloidalpha-adrenergic drug;
antidyskinesia agent;
antiparkinson drug;
dopamine agonist;
emetic;
serotonergic drug
metergoline[no description available]medium10carbamate ester;
ergoline alkaloid		dopamine agonist;
geroprotector;
serotonergic antagonist
ergoline[no description available]medium10diamine;
ergoline alkaloid;
indole alkaloid fundamental parent;
indole alkaloid;
organic heterotetracyclic compound
p-chloroamphetamine[no description available]medium60
glutamic acid[no description available]medium10glutamic acid;
glutamine family amino acid;
L-alpha-amino acid;
proteinogenic amino acid		Escherichia coli metabolite;
ferroptosis inducer;
micronutrient;
mouse metabolite;
neurotransmitter;
nutraceutical
racemetirosine[no description available]medium10
xylazine[no description available]medium101,3-thiazine;
methylbenzene;
secondary amino compound		alpha-adrenergic agonist;
analgesic;
emetic;
muscle relaxant;
sedative
oxotremorine[no description available]medium10N-alkylpyrrolidine
gamma-aminobutyric acid[no description available]medium10amino acid zwitterion;
gamma-amino acid;
monocarboxylic acid		human metabolite;
neurotransmitter;
Saccharomyces cerevisiae metabolite;
signalling molecule
levodopa[no description available]medium20amino acid zwitterion;
dopa;
L-tyrosine derivative;
non-proteinogenic L-alpha-amino acid		allelochemical;
antidyskinesia agent;
antiparkinson drug;
dopaminergic agent;
hapten;
human metabolite;
mouse metabolite;
neurotoxin;
plant growth retardant;
plant metabolite;
prodrug
dibenzepin[no description available]medium10dibenzodiazepine
p-hydroxyamphetamine[no description available]medium10amphetamines
glutathione disulfide[no description available]medium10glutathione derivative;
organic disulfide		Escherichia coli metabolite;
mouse metabolite
deoxyglucose[no description available]medium10
fenclonine[no description available]medium50phenylalanine derivative
tyrosine[no description available]medium30amino acid zwitterion;
erythrose 4-phosphate/phosphoenolpyruvate family amino acid;
L-alpha-amino acid;
proteinogenic amino acid;
tyrosine		EC 1.3.1.43 (arogenate dehydrogenase) inhibitor;
fundamental metabolite;
micronutrient;
nutraceutical
phenylalanine[no description available]medium20amino acid zwitterion;
erythrose 4-phosphate/phosphoenolpyruvate family amino acid;
L-alpha-amino acid;
phenylalanine;
proteinogenic amino acid		algal metabolite;
EC 3.1.3.1 (alkaline phosphatase) inhibitor;
Escherichia coli metabolite;
human xenobiotic metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite
octopamine[no description available]medium20phenylethanolamines;
tyramines		neurotransmitter
(4-(m-chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium chloride[no description available]medium10
dimethylphenylpiperazinium iodide[no description available]medium10N-arylpiperazine;
organic iodide salt;
piperazinium salt;
quaternary ammonium salt		nicotinic acetylcholine receptor agonist
dihydroxyphenylalanine[no description available]medium10hydroxyphenylalanine;
non-proteinogenic alpha-amino acid;
tyrosine derivative		human metabolite
tyramine[no description available]medium21monoamine molecular messenger;
primary amino compound;
tyramines		EC 3.1.1.8 (cholinesterase) inhibitor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
neurotransmitter
benserazide[no description available]medium10carbohydrazide;
catechols;
primary alcohol;
primary amino compound		antiparkinson drug;
dopaminergic agent;
EC 4.1.1.28 (aromatic-L-amino-acid decarboxylase) inhibitor
guanosine triphosphate[no description available]medium20guanosine 5'-phosphate;
purine ribonucleoside 5'-triphosphate		Escherichia coli metabolite;
mouse metabolite;
uncoupling protein inhibitor
hexestrol[no description available]medium10stilbenoid
urea[no description available]medium10isourea;
monocarboxylic acid amide;
one-carbon compound		Daphnia magna metabolite;
Escherichia coli metabolite;
fertilizer;
flour treatment agent;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
fluorescamine[no description available]medium10
mescaline[no description available]medium10methoxybenzenes;
phenethylamine alkaloid;
primary amino compound		hallucinogen
nialamide[no description available]medium20organonitrogen compound;
organooxygen compound
tranylcypromine[no description available]medium602-phenylcyclopropan-1-amine
dizocilpine maleate[no description available]medium30maleate salt;
tetracyclic antidepressant		anaesthetic;
anticonvulsant;
neuroprotective agent;
nicotinic antagonist;
NMDA receptor antagonist
ly 274614[no description available]medium10
hydroxymaprotilin[no description available]medium10
cyclo(leucylglycine)[no description available]medium10
tianeptine[no description available]medium10dibenzothiazepine;
monocarboxylic acid;
organochlorine compound
cyanopindolol[no description available]medium10indoles
sodium fluoride[no description available]medium10fluoride saltmutagen
guanylyl imidodiphosphate[no description available]medium10nucleoside triphosphate analogue
azides[no description available]medium10pseudohalide anionmitochondrial respiratory-chain inhibitor
gtp gamma-4-azidoanilide[no description available]medium10
phenelzine[no description available]medium30primary amine
norfenfluramine[no description available]medium10amphetamines
ubenimex[no description available]medium10
thiorphan[no description available]medium10N-acyl-amino acid
u 78753e[no description available]medium10
cyclopentane[no description available]medium10cycloalkane;
cyclopentanes;
volatile organic compound		non-polar solvent
3-methoxy-4-hydroxyphenylglycol sulfate[no description available]medium10alcohol;
phenols
isoproterenol[no description available]medium20catechols;
secondary alcohol;
secondary amino compound		beta-adrenergic agonist;
bronchodilator agent;
cardiotonic drug;
sympathomimetic agent
naloxone[no description available]medium10morphinane alkaloid;
organic heteropentacyclic compound;
tertiary alcohol		antidote to opioid poisoning;
central nervous system depressant;
mu-opioid receptor antagonist
inosinic acid[no description available]medium10inosine phosphate;
purine ribonucleoside 5'-monophosphate		Escherichia coli metabolite;
human metabolite;
mouse metabolite
albuterol[no description available]medium10phenols;
phenylethanolamines;
secondary amino compound		beta-adrenergic agonist;
bronchodilator agent;
environmental contaminant;
xenobiotic
dobutamine[no description available]medium10catecholamine;
secondary amine		beta-adrenergic agonist;
cardiotonic drug;
sympathomimetic agent
cysteine[no description available]medium10cysteiniumfundamental metabolite
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine[no description available]medium20methylpyridines;
phenylpyridine;
tetrahydropyridine		neurotoxin
aconitine[no description available]medium10
lithium carbonate[no description available]medium10carbonate salt;
lithium salt		antimanic drug
4-hydroxyphenethylene glycol[no description available]medium10phenols
thorium dioxide[no description available]medium20thorium molecular entity
ergotamine[no description available]medium10peptide ergot alkaloidalpha-adrenergic agonist;
mycotoxin;
non-narcotic analgesic;
oxytocic;
serotonergic agonist;
vasoconstrictor agent
1-propanol[no description available]medium10propan-1-ols;
short-chain primary fatty alcohol		metabolite;
protic solvent
chlorine[no description available]medium10diatomic chlorine;
gas molecular entity		bleaching agent
phencyclidine[no description available]medium10benzenes;
piperidines		anaesthetic;
neurotoxin;
NMDA receptor antagonist;
psychotropic drug
acid phosphatase[no description available]medium10
isocarboxazid[no description available]medium20benzenes
dronabinol[no description available]medium10benzochromene;
diterpenoid;
phytocannabinoid;
polyketide		cannabinoid receptor agonist;
epitope;
hallucinogen;
metabolite;
non-narcotic analgesic
hydrogen[no description available]medium10elemental hydrogen;
elemental molecule;
gas molecular entity		antioxidant;
electron donor;
food packaging gas;
fuel;
human metabolite
oxazepam[no description available]medium101,4-benzodiazepinone;
organochlorine compound		anxiolytic drug;
environmental contaminant;
xenobiotic
isomethyleugenol[no description available]medium10isomethyleugenol
humulene[no description available]medium10alpha-humulene
indoleacetamide[no description available]low00indoles;
monocarboxylic acid amide;
N-acylammonia		bacterial metabolite;
fungal metabolite;
plant metabolite
bisindolylmaleimide iii[no description available]low00indoles;
maleimides		EC 2.7.11.13 (protein kinase C) inhibitor
bisindolylmaleimide iv[no description available]low00indoles;
maleimides
bisindolylmaleimide v[no description available]low00indoles
chetomin[no description available]low00indoles;
organic disulfide;
organic heteropentacyclic compound		Chaetomium metabolite;
immunosuppressive agent
dapi[no description available]low00indolesfluorochrome
3,3'-diindolylmethane[no description available]low00indolesantineoplastic agent;
P450 inhibitor
gö6983[no description available]low00indoles;
maleimides
ic 261[no description available]low00indoles
indapamide[no description available]low00indoles;
organochlorine compound;
sulfonamide		antihypertensive agent;
diuretic
indolepropanol phosphate[no description available]low00indoles;
monoalkyl phosphate
linopirdine[no description available]low00indoles
3-[(3,5-dibromo-4-hydroxyphenyl)methylidene]-5-iodo-1H-indol-2-one[no description available]low00indoles
ro 31-8220[no description available]low00imidothiocarbamic ester;
indoles;
maleimides		EC 2.7.11.13 (protein kinase C) inhibitor
ici 204,219[no description available]low00carbamate ester;
indoles;
N-sulfonylcarboxamide		anti-asthmatic agent;
leukotriene antagonist
adrenochrome[no description available]low00indoles
5-bromoisatin[no description available]low00indolesanticoronaviral agent
etryptamine[no description available]low00indoles
hydroxytryptophol[no description available]low00indoles
indole-3-carbaldehyde[no description available]low00heteroarenecarbaldehyde;
indole alkaloid;
indoles		bacterial metabolite;
human xenobiotic metabolite;
marine metabolite;
plant metabolite
indican[no description available]low00aryl sulfate;
indoles		human metabolite
indoline[no description available]low00indoles
indoxyl acetate[no description available]low00indoles
methoxytryptophol[no description available]low00indoles
5-methoxyindole[no description available]low00indoles
mebhydroline[no description available]low00indoles
oxyphenisatin[no description available]low00indoles
5-Methoxyisatin[no description available]low00indolesanticoronaviral agent
indalpine[no description available]low00indoles
5-bromo-4-chloro-3-indoxyl phosphate[no description available]low00aryl phosphate;
indoles;
organobromine compound;
organochlorine compound		chromogenic compound
geneserine[no description available]low00indoles
ropinirole hydrochloride[no description available]low00indoles
tinazoline[no description available]low00indoles
n-acetyltryptamine[no description available]low00acetamides;
indoles
mepindolol[no description available]low00indoles
eletriptan[no description available]low00indoles;
N-alkylpyrrolidine;
sulfone		non-steroidal anti-inflammatory drug;
serotonergic agonist;
vasoconstrictor agent
5-methoxyindole-3-carbaldehyde[no description available]low00indoles
6-chloroindole[no description available]low00indoles
5-Chloro-1H-indole-2,3-dione[no description available]low00indolesanticoronaviral agent
5-iodoisatin[no description available]low00indolesanticoronaviral agent
lyngbyatoxin a[no description available]low00indoles
indolactam v[no description available]low00indoles
indo-1[no description available]low00indolesfluorochrome
ramosetron hydrochloride[no description available]low00indoles
ramosetron[no description available]low00indoles
5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole[no description available]low00indoles
echinuline[no description available]low002,5-diketopiperazines;
indole alkaloid;
indoles;
olefinic compound		Aspergillus metabolite;
marine metabolite;
plant metabolite
luzindole[no description available]low00acetamides;
indoles		melatonin receptor antagonist
almotriptan[no description available]low00indoles;
sulfonamide;
tertiary amine		non-steroidal anti-inflammatory drug;
serotonergic agonist;
vasoconstrictor agent
sb 200646[no description available]low00indoles
tilivalline[no description available]low00indole alkaloid;
indoles;
phenols;
pyrrolobenzodiazepine		bacterial metabolite;
microtubule-stabilising agent;
toxin
asperlicin c[no description available]low00asperlicins;
indoles;
organic heterotetracyclic compound		Aspergillus metabolite;
cholecystokinin antagonist
sandoz-21-009[no description available]low00indoles
pendolmycin[no description available]low00indolesmetabolite
varespladib[no description available]low00aromatic ether;
benzenes;
dicarboxylic acid monoamide;
indoles;
monocarboxylic acid;
primary carboxamide		anti-inflammatory drug;
antidote;
EC 3.1.1.4 (phospholipase A2) inhibitor
leukodopachrome[no description available]low00hydroxy monocarboxylic acid;
indoles		metabolite
3,3-bis(4-hydroxy-3-methylphenyl)-1H-indol-2-one[no description available]low00indoles
3-methyleneindolenine[no description available]low00indolesmetabolite
sb 216763[no description available]low00indoles;
maleimides
enzastaurin[no description available]low00indoles;
maleimides
brevianamide f[no description available]low00dipeptide;
indoles;
pyrrolopyrazine		metabolite
3-(hydroxyacetyl)indole[no description available]low00indoles
roxindole[no description available]low00indolesalpha-adrenergic antagonist;
serotonergic drug
5-Fluoroisatin[no description available]low00indolesanticoronaviral agent
beta-indol-3-yl-glucoside[no description available]low00glycoside;
indoles
2-methyl-3-(phenylmethylthio)-1H-indole[no description available]low00indoles
indole-3-acetonitrile[no description available]low00indoles;
nitrile		auxin;
human xenobiotic metabolite;
plant hormone;
plant metabolite
10H-[1]benzothiolo[3,2-b]indole[no description available]low00indoles
2,2,2-trifluoro-N-[2-(1H-indol-3-yl)ethyl]acetamide[no description available]low00indoles;
secondary carboxamide;
trifluoroacetamide
physovenine[no description available]low00indoles
dendrobine[no description available]low00indoles
ck-0944666[no description available]low00benzamides;
indoles;
organofluorine compound		actin polymerisation inhibitor
methyl indole-3-carboxylate[no description available]low00indoles;
methyl ester		metabolite
2-(1H-indol-3-ylthio)acetic acid[no description available]low00indoles
3-(4-pyridyl)-1h-indole[no description available]low00indoles
1-(2,3-dihydroindol-1-yl)-2-(5-pyridin-4-yl-2-tetrazolyl)ethanone[no description available]low00indoles
2-(6-cyano-1-indolyl)-N-cyclohexylacetamide[no description available]low00indoles
1-methyl-2-[(4-methyl-1-piperidinyl)methyl]-3-indolecarbonitrile[no description available]low00indoles
4-(1-methylsulfonyl-2,3-dihydroindol-5-yl)-N-(2-oxolanylmethyl)-2-thiazolamine[no description available]low00indoles
N-[4-(2-methyl-1-methylsulfonyl-2,3-dihydroindol-5-yl)-2-thiazolyl]-2-thiophen-2-ylacetamide[no description available]low00indoles
1-[5-(2-amino-5-methyl-4-thiazolyl)-2,3-dihydroindol-1-yl]-1-butanone[no description available]low00indoles
2-(2-methyl-1H-indol-3-yl)ethanol[no description available]low00indoles
2-(2-ethyl-1-piperidinyl)-1-(2-methyl-1H-indol-3-yl)ethanone[no description available]low00indoles
1-(2,6-dimethyl-1H-indol-3-yl)-2-(1-pyrrolidinyl)ethanone[no description available]low00indoles
1-methyl-2-[(phenylthio)methyl]-3-indolecarbonitrile[no description available]low00indoles
1-(2,3-dihydroindol-1-yl)-2-(phenylthio)ethanone[no description available]low00indoles
2-(2,3-dihydroindol-1-yl)-N,N-dimethylethanamine[no description available]low00indoles
8-(1H-indol-3-ylmethylidene)-6,10-dioxaspiro[4.5]decane-7,9-dione[no description available]low00indoles
N-(1-acetyl-2-chloro-3-indolyl)-2-chloroacetamide[no description available]low00indoles
4-(5-methoxy-1,2-dimethyl-3-indolyl)-2-thiazolamine[no description available]low00indoles
N-(1-acetyl-2,3-dihydroindol-5-yl)-4-methylbenzamide[no description available]low00indoles
oncrasin-1[no description available]low00arenecarbaldehyde;
indoles;
monochlorobenzenes		antineoplastic agent;
apoptosis inducer
1-(2-methyl-1H-indol-3-yl)-2-(2-thiazolylamino)ethanone[no description available]low00indoles
N-(2-fluorophenyl)-2-[3-(1-oxopropyl)-1-indolyl]acetamide[no description available]low00indoles
2-(3-acetyl-1-indolyl)-N-(2,4-dimethylphenyl)acetamide[no description available]low00indoles
4-amino-2-[[2-(2,3-dihydroindol-1-yl)-2-oxoethyl]thio]-5-pyrimidinecarboxylic acid ethyl ester[no description available]low00indoles
LSM-33266[no description available]low00indoles
1-oxo-3-(1-piperidinyl)-5,6,7,8-tetrahydropyrrolo[1,2-a]indole-2-carbonitrile[no description available]low00indoles
[1-(2-phenoxyethyl)-3-indolyl]-(1-pyrrolidinyl)methanethione[no description available]low00indoles
N-[4-(1-methylsulfonyl-2,3-dihydroindol-5-yl)-2-thiazolyl]acetamide[no description available]low00indoles
1-[2-(1H-indol-3-yl)ethyl]-5,6,7,8-tetrahydroquinolin-4-one[no description available]low00indoles
N,N-diethylcarbamodithioic acid [2-(2-methyl-1H-indol-3-yl)-2-oxoethyl] ester[no description available]low00indoles
1-(3-phenoxypropyl)-3-indolecarbonitrile[no description available]low00indoles
1-[(3,4-dichlorophenyl)methyl]indole-2,3-dione[no description available]low00indoles
2-[[1-[(3-fluorophenyl)methyl]-3-indolyl]sulfonyl]-N-(5-methyl-3-isoxazolyl)acetamide[no description available]low00indoles
1-[2-(2,5-dimethyl-1H-indol-3-yl)ethyl]-3-methyl-1-(thiophen-2-ylmethyl)thiourea[no description available]low00indoles
2-(1H-indol-3-yl)-2-oxo-N-(2-thiazolyl)acetamide[no description available]low00indoles
N-(2-furanylmethyl)-2-[3-(1-oxo-2-phenoxyethyl)-1-indolyl]acetamide[no description available]low00indoles
4-(1H-indol-3-yl)butanoic acid [2-(4-amino-1,3-dimethyl-2,6-dioxo-5-pyrimidinyl)-2-oxoethyl] ester[no description available]low00indoles
2,5-dimethyl-3-furancarboxylic acid [2-(2,3-dihydroindol-1-yl)-2-oxoethyl] ester[no description available]low00indoles
2-chloro-3-pyridinecarboxylic acid [2-(2,3-dihydroindol-1-yl)-2-oxoethyl] ester[no description available]low00indoles
4-(1H-indol-3-yl)butanoic acid [2-(3-methoxyanilino)-2-oxoethyl] ester[no description available]low00indoles
2-(2,3-dihydro-1H-inden-5-yloxy)-1-(2,3-dihydroindol-1-yl)ethanone[no description available]low00indoles
1H-indol-3-yl(pyridin-2-yl)methanol[no description available]low00indoles
N-(1H-indol-5-yl)-2-thiophenecarboxamide[no description available]low00indoles
4-[[1-[(3,4-dichlorophenyl)methyl]-3-indolyl]-(3-methyl-5-oxo-1,2-dihydropyrazol-4-yl)methyl]-5-methyl-1,2-dihydropyrazol-3-one[no description available]low00indoles
2-methyl-3-[(2-methyl-1H-indol-3-yl)-(2-pyridinyl)methyl]-1H-indole[no description available]low00indoles
N-[amino-[2-(1H-indol-3-yl)ethylimino]methyl]-4-chlorobenzamide[no description available]low00indoles
3-[2-(2,4-dimethyl-3-furanyl)-2-oxoethyl]-3-hydroxy-1-(2-phenylethyl)-2-indolone[no description available]low00indoles
1-[2-(hydroxymethyl)-1-benzimidazolyl]-3-(1-indolyl)-2-propanol[no description available]low00indoles
6-(2-chlorophenyl)-3-methyl-2-[4-morpholinyl(oxo)methyl]-1,5,6,7-tetrahydroindol-4-one[no description available]low00indoles
3-methyl-4-oxo-1,5,6,7-tetrahydroindole-2-carboxylic acid (4-methylcyclohexyl) ester[no description available]low00indoles
5-[[(5-ethyl-[1,2,4]triazino[5,6-b]indol-3-yl)thio]methyl]-2-furancarboxylic acid methyl ester[no description available]low00indoles
N-[2-(diethylamino)ethyl]-5-[(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide[no description available]low00indoles
2-[(prop-2-enylthio)-(4,5,6,7-tetrahydro-1H-indol-2-yl)methylidene]propanedinitrile[no description available]low00indoles
2-[[5-(dimethylsulfamoyl)-1H-indol-3-yl]methylidene]propanedioic acid diethyl ester[no description available]low00indoles
5-methyl-1-[3-(2-methylphenoxy)propyl]indole-2,3-dione[no description available]low00indoles
N-[2-(1H-indol-3-yl)ethyl]-4-(phenylmethyl)-5-thieno[3,2-b]pyrrolecarboxamide[no description available]low00indoles
1-[cyclopropyl(oxo)methyl]-N-(2-hydroxyethyl)-N-(phenylmethyl)-2,3-dihydroindole-5-sulfonamide[no description available]low00indoles
5-bromo-1-(1-oxopropyl)-N,N-dipropyl-2,3-dihydroindole-7-sulfonamide[no description available]low00indoles
4-(1-methyl-3-indolyl)-N-propan-2-ylbutanamide[no description available]low00indoles
4-(2,3-dihydroindol-1-yl)-N-[3-(N-ethyl-3-methylanilino)propyl]-3-(1-imidazolyl)-4-oxobutanamide[no description available]low00indoles
1-[[5-bromo-1-[cyclopropyl(oxo)methyl]-2,3-dihydroindol-7-yl]sulfonyl]-4-piperidinecarboxylic acid ethyl ester[no description available]low00indoles
N-[2-(2-methyl-1-indolyl)ethyl]benzamide[no description available]low00indoles
3-[[5-bromo-1-[cyclopropyl(oxo)methyl]-2,3-dihydroindol-7-yl]sulfonyl]-N-[(5-methyl-2-furanyl)methyl]propanamide[no description available]low00indoles
acetic acid [2-(1-acetyl-6-indolyl)-2-oxoethyl] ester[no description available]low00indoles
N-[2-(1-cyclohexenyl)ethyl]-1-[cyclopropyl(oxo)methyl]-2,3-dihydroindole-5-sulfonamide[no description available]low00indoles
4-[2-[[1-[(2-methylphenyl)methyl]-3-indolyl]sulfonyl]-1-oxoethyl]-1-piperazinecarboxylic acid ethyl ester[no description available]low00indoles
N-[4-(dimethylamino)phenyl]-2-(1-oxo-[1,2,4]triazino[4,5-a]indol-2-yl)acetamide[no description available]low00indoles
N-(3-methoxyphenyl)-2-(1-methyl-3-indolyl)acetamide[no description available]low00indoles
cyclobutyl-[5-[(2-ethyl-1-piperidinyl)sulfonyl]-2,3-dihydroindol-1-yl]methanone[no description available]low00indoles
n-(1-methyl-5-indolyl)-n'-(3-methyl-5-isothiazolyl)urea[no description available]low001,2-thiazoles;
indoles;
ureas		receptor modulator;
serotonergic antagonist
n-pentanoyl-2-benzyltryptamine[no description available]low00indoles
2-[[1-(phenylmethyl)-3-indolyl]thio]-N-(2-thiazolyl)acetamide[no description available]low00indoles
[1-[2-(2-methylphenoxy)ethyl]-3-indolyl]-(4-methyl-1-piperazinyl)methanethione[no description available]low00indoles
1-(Chloroacetyl)-3-(1H-indol-3-yl)-5-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-4-ol[no description available]low00indolesanticoronaviral agent
N-[(1,2-dimethyl-5-indolyl)methyl]-2-methyl-3-nitrobenzamide[no description available]low00indoles
N-(2-furanylmethyl)-2-[[5-[(2-methyl-1H-indol-3-yl)methyl]-1,3,4-oxadiazol-2-yl]thio]acetamide[no description available]low00indoles
l 663536[no description available]low00aryl sulfide;
indoles;
monocarboxylic acid;
monochlorobenzenes		antineoplastic agent;
EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor;
leukotriene antagonist
2-[(1-methyl-3-indolyl)thio]-N-(2-thiazolyl)acetamide[no description available]low00indoles
Nb-Palmitoyltryptamine[no description available]low00indoles
rs 17053[no description available]low00indoles
N-[2-(2-chlorophenoxy)ethyl]-2-(1H-indol-3-yl)-2-oxoacetamide[no description available]low00indoles
1-(1H-indol-3-yl)-2-[(6-methyl-2-nitro-3-pyridinyl)oxy]ethanone[no description available]low00indoles
1-[2-(5-chloro-2-methyl-1H-indol-3-yl)ethyl]-3-ethyl-1-(2-furanylmethyl)thiourea[no description available]low00indoles
5-bromo-N-[(1,2-dimethyl-5-indolyl)methyl]-2-furancarboxamide[no description available]low00indoles
1-[(1,2-dimethyl-5-indolyl)methyl]-3-(phenylmethyl)thiourea[no description available]low00indoles
4-chloro-N-[2-(1H-indol-3-yl)-1-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)ethyl]benzamide[no description available]low00indoles
1-cyclohexyl-3-[(1,2-dimethyl-5-indolyl)methyl]urea[no description available]low00indoles
5-bromo-N-[2-(2-methyl-1-indolyl)ethyl]-2-furancarboxamide[no description available]low00indoles
le 300[no description available]low00indoles
4-[(1,2-dimethyl-5-indolyl)methylamino]-4-oxobutanoic acid[no description available]low00indoles
5-Nitroisatin[no description available]low00indolesanticoronaviral agent
1-[2-(2,4-dichlorophenyl)-2-(1H-indol-3-yl)ethyl]-3-[3-(dimethylamino)propyl]thiourea[no description available]low00indoles
N-[2-[4-(dimethylamino)phenyl]-2-(1H-indol-3-yl)ethyl]benzamide[no description available]low00indoles
2,6-difluoro-N-[2-[3-[(2-fluorophenyl)methylthio]-1-indolyl]ethyl]benzamide[no description available]low00indoles
ro 60-0175[no description available]low00indoles;
organochlorine compound;
organofluorine compound;
primary amino compound
N-[(1,2-dimethyl-5-indolyl)methyl]-2-(4-nitrophenyl)acetamide[no description available]low00indoles
2-[[4-amino-5-(3,4-dimethoxyphenyl)-1,2,4-triazol-3-yl]thio]-1-(1H-indol-3-yl)-2-phenylethanone[no description available]low00indoles
1-acetyl-N-[3-(N-ethyl-3-methylanilino)propyl]-2,3-dihydroindole-5-sulfonamide[no description available]low00indoles
3-[3-[(5-ethyl-[1,2,4]triazino[5,6-b]indol-3-yl)thio]propyl]-1H-benzimidazol-2-one[no description available]low00indoles
koumine[no description available]low00indoles
AG-370[no description available]low00indoles
(6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid[no description available]low00dihydroxy monocarboxylic acid;
indoles;
organofluorine compound
apaziquone[no description available]low00indoles
amaranthin betacyanin[no description available]low00disaccharide derivative;
indoles;
olefinic compound;
tetrahydropyridine		biological pigment;
plant metabolite
(5-ethyl-8-methyl-[1,2,4]triazino[5,6-b]indol-3-yl)hydrazine[no description available]low00indoles
chaetoglobosin A[no description available]low00cytochalasan alkaloid;
epoxide;
indoles;
macrocycle;
secondary alpha-hydroxy ketone		Chaetomium metabolite
LSM-18452[no description available]low00indoles
(2R,4R)-4-(1-acetyl-3-indolyl)-2-[[4-(hydroxymethyl)phenyl]methoxy]-N-(phenylmethyl)-3,4-dihydro-2H-pyran-6-carboxamide[no description available]low00indoles
vilazodone[no description available]low001-benzofurans;
indoles;
monocarboxylic acid amide;
N-alkylpiperazine;
N-arylpiperazine;
nitrile		antidepressant;
serotonergic agonist;
serotonin uptake inhibitor
cyclo(glycyltryptophyl)[no description available]low00indolesmetabolite
2-[(1R,3S)-3-(7-bromo-2-methyl-1H-indol-3-yl)-2,2-dimethylcyclopropyl]acetonitrile[no description available]low00indoles
(11S,14S)-Cyclo-(L-Trp-L-Phe)[no description available]low00indolesAspergillus metabolite
LSM-3706[no description available]low00indoles
LSM-3511[no description available]low00indoles
LSM-2818[no description available]low00indoles
tryprostatin b[no description available]low00dipeptide;
indole alkaloid;
indoles;
pyrrolopyrazine
l 779976[no description available]low00benzimidazoles;
indoles;
piperidinecarboxamide;
primary amino compound;
secondary carboxamide		neuroprotective agent;
somatostatin receptor agonist
tmc-95a[no description available]low00indoles;
lactam;
macrocycle;
phenols;
secondary alcohol;
tertiary alcohol		antimicrobial agent;
antineoplastic agent;
bacterial metabolite;
fungal metabolite;
proteasome inhibitor
nematophin[no description available]low00indoles
molindone hydrochloride[no description available]low00indoles
varespladib methyl[no description available]low00aromatic ether;
benzenes;
indoles;
methyl ester;
primary carboxamide		anti-inflammatory drug;
antidote;
EC 3.1.1.4 (phospholipase A2) inhibitor;
prodrug
am 694[no description available]low00aromatic ketone;
indoles;
organofluorine compound;
organoiodine compound;
synthetic cannabinoid		cannabinoid receptor agonist
tryprostatin a[no description available]low00aromatic ether;
dipeptide;
indole alkaloid;
indoles;
pyrrolopyrazine		breast cancer resistance protein inhibitor
way-362450[no description available]low00indoles
fumiquinazoline f[no description available]low00fumiquinazoline;
indoles;
pyrazinoquinazoline
5-chloro-2-methyl-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1h-indole[no description available]low00indoles
a 443654[no description available]low00indoles
noradrenochrome[no description available]low00indoles
sotrastaurin[no description available]low00indoles;
maleimides;
N-alkylpiperazine;
N-arylpiperazine;
quinazolines		anticoronaviral agent;
EC 2.7.11.13 (protein kinase C) inhibitor;
immunosuppressive agent
tmc-95b[no description available]low00indoles;
lactam;
macrocycle;
phenols;
secondary alcohol;
tertiary alcohol		antimicrobial agent;
antineoplastic agent;
fungal metabolite;
proteasome inhibitor
chromopyrrolic acid[no description available]low00indoles;
pyrroledicarboxylic acid		bacterial metabolite
arq 197[no description available]low00indoles
quisinostat[no description available]low00indoles
pf-562,271[no description available]low00indoles
Dihydro-beta-erythroidine hydrobromide[no description available]low00indoles
N-[5-(2,3-dihydroindol-1-ylsulfonyl)-1,3,4-thiadiazol-2-yl]-3-methylbutanamide[no description available]low00indoles
complestatin[no description available]low00cyclic ether;
heterodetic cyclic peptide;
indoles;
organic heterobicyclic compound;
organochlorine compound;
peptide antibiotic;
polyphenol		anti-HIV-1 agent;
antimicrobial agent;
HIV-1 integrase inhibitor;
metabolite
neuroprotectin a[no description available]low00cyclic ether;
heterodetic cyclic peptide;
indoles;
organochlorine compound;
polyphenol		HIV-1 integrase inhibitor;
metabolite
2-[3-[[2-oxo-2-(1-pyrrolidinyl)ethyl]thio]-1-indolyl]-N,N-di(propan-2-yl)acetamide[no description available]low00indoles
1-[3-[(2R,4R)-2-[[4-(hydroxymethyl)phenyl]methoxy]-6-[oxo-[4-(phenylmethyl)-1-piperazinyl]methyl]-3,4-dihydro-2H-pyran-4-yl]-1-indolyl]ethanone[no description available]low00indoles
3-[(1-methyl-3-indolyl)methylidene]-1H-pyrrolo[3,2-b]pyridin-2-one[no description available]low00indoles
2-[1-[2-(diethylamino)-2-oxoethyl]-3-indolyl]-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-oxoacetamide[no description available]low00indoles
1-[(2-oxo-1,3-dihydroindol-5-yl)sulfonyl]-4-piperidinecarboxylic acid ethyl ester[no description available]low00indoles
N-(4-propan-2-ylphenyl)-1-[(1,3,3-trimethyl-2-oxo-5-indolyl)sulfonyl]-4-piperidinecarboxamide[no description available]low00indoles
N-[4-[1-(1-oxopropyl)-2,3-dihydroindol-5-yl]-2-thiazolyl]-2-furancarboxamide[no description available]low00indoles
cink4[no description available]low00indoles
chondramide c[no description available]low00chondramide;
indoles;
phenols		antineoplastic agent;
bacterial metabolite
2-[[1-[(3-chlorophenyl)methyl]-3-indolyl]sulfonyl]-N-(5-methyl-3-isoxazolyl)acetamide[no description available]low00indoles
2-[[1-[(3-bromophenyl)methyl]-3-indolyl]sulfonyl]-N-(5-methyl-3-isoxazolyl)acetamide[no description available]low00indoles
wasalexin a[no description available]low00indoles
chondramide a[no description available]low00chondramide;
indoles;
phenols		antineoplastic agent;
bacterial metabolite
(3R)-4-[2-(1H-indol-4-yl)-6-(1-methylsulfonylcyclopropyl)-4-pyrimidinyl]-3-methylmorpholine[no description available]low00indoles
gsk2656157[no description available]low00biaryl;
indoles;
methylpyridines;
organofluorine compound;
pyrrolopyrimidine;
tertiary carboxamide		antineoplastic agent;
EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor;
PERK inhibitor
AZD3463[no description available]low00aminopiperidine;
aminopyrimidine;
indoles;
monomethoxybenzene;
organochlorine compound;
secondary amino compound;
tertiary amino compound		antineoplastic agent;
apoptosis inducer;
autophagy inducer;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
osimertinib[no description available]low00acrylamides;
aminopyrimidine;
biaryl;
indoles;
monomethoxybenzene;
secondary amino compound;
secondary carboxamide;
substituted aniline;
tertiary amino compound		antineoplastic agent;
epidermal growth factor receptor antagonist
acarbose[no description available]low00chondramide;
indoles;
organochlorine compound;
phenols		antineoplastic agent;
bacterial metabolite
chondramide d[no description available]low00chondramide;
indoles;
phenols		antineoplastic agent;
bacterial metabolite
THZ531[no description available]low00aminopyrimidine;
enamide;
indoles;
N-acylpiperidine;
organochlorine compound;
secondary amino compound;
secondary carboxamide		antineoplastic agent;
apoptosis inducer;
EC 2.7.11.22 (cyclin-dependent kinase) inhibitor
lugdunin[no description available]low00homodetic cyclic peptide;
indoles;
macrocycle;
peptide antibiotic;
thiazolidines		human metabolite;
rat metabolite
tegaserod[no description available]low00carboxamidine;
guanidines;
hydrazines;
indoles		gastrointestinal drug;
serotonergic agonist
brassilexin[no description available]low00indoles
indolmycin[no description available]low001,3-oxazoles;
indoles;
secondary amino compound		antibacterial agent;
antimicrobial agent;
bacterial metabolite;
EC 6.1.1.2 (tryptophan--tRNA ligase) inhibitor
N'-(1h-indol-3-ylmethylene)benzohydrazide[no description available]low00indoles
ConditionIndicatedRelationship StrengthStudiesTrials
Ache0low10
Acute Disease0low10
Adipocere0low10
Adjustment Disorder0low20
Adjustment Disorders0low20
Adrenal Gland Diseases0low10
Adverse Drug Event0low20
Adverse Drug Reaction0low20
Affective Disorders, Psychotic0low10
Affective Psychosis, Bipolar0medium31
Aggression0low40
Algor Mortis0low10
Alveolar Proteinoses, Pulmonary0low10
Alveolar Proteinosis, Pulmonary0low10
Alveolitis, Fibrosing0low20
Amentia0low10
Anesthesia0low10
Anniversary Reaction0low20
Anorexia0low10
Anxiety0medium11
Appetite Disorders0low10
Arrhythmia0low30
Arrhythmias, Cardiac0low30
Arrythmia0low30
Bilateral Headache0medium11
Bile Duct Obstruction0low20
Biliary Stasis0low20
Bipolar Disorder0medium31
Bipolar Mood Disorder0medium31
Body Weight0low10
Brain Diseases0low10
Brain Disorders0low10
Cancer of Lung0low20
Cancer of the Lung0low20
Cardiac Arrhythmia0low30
Cardiac Arrhythmias0low30
Cardiac Dysrhythmia0low30
Cardiomyopathies0low10
Cardiomyopathies, Primary0low10
Cardiomyopathies, Secondary0low10
Cataract0low10
Cataract, Membranous0low10
Central Nervous System Disorders, Intracranial0low10
Central Nervous System Intracranial Disorders0low10
Cephalalgia0medium11
Cephalgia0medium11
Cephalodynia0medium11
Cholestasis0low20
Chronic Disease0low10
Chronic Illness0low10
Chronic Insomnia0medium11
Chronically Ill0low10
CNS Disorders, Intracranial0low10
Corneal Diseases0low10
Cranial Pain0medium11
Cruor0low10
Death, Sudden0low10
Delayed Effects, Prenatal Exposure0low20
Dementia0low10
Depression0medium83
Depression, Bipolar0medium31
Depression, Endogenous0low60
Depression, Neurotic0low60
Depression, Reactive0low20
Depression, Reactive, Psychotic0low10
Depression, Unipolar0low60
Depressive Syndrome0low60
DIMS (Disorders of Initiating and Maintaining Sleep)0medium11
Disease Models, Animal0low50
Disease, Pulmonary0low20
Diseases, Pulmonary0low20
Disorders of Initiating and Maintaining Sleep0medium11
Drug Overdose0low10
Drug Side Effects0low20
Drug Toxicity0low20
Drug Withdrawal Symptoms0low10
Drug-Related Side Effects and Adverse Reactions0low20
Early Awakening0medium11
Eating and Feeding Disorders0low10
Eating Disorders0low10
Edema, Pulmonary0low10
Edemas, Pulmonary0low10
Encephalon Diseases0low10
Encephalopathy0low10
Exophthalmos0low10
Familial Dementia0low10
Feeding and Eating Disorders0low10
Feeding Disorders0low10
Fibroses, Pulmonary0low20
Fibrosis, Pulmonary0low20
Generalized Headache0medium11
Head Pain0medium11
Headache0medium11
Hemicrania0medium11
Hypothermia0low10
Hypothermia, Accidental0low10
Idiopathic Diffuse Interstitial Pulmonary Fibrosis0low20
Insomnia0medium11
Insomnia Disorder0medium11
Intracranial Central Nervous System Disorders0low10
Intracranial CNS Disorders0low10
Kidney Diseases0low10
Late Effects, Prenatal Exposure0low20
Lens Opacities0low10
Lipidoses0low200
Lipidosis0low200
Lipoidosis0low200
Livor Mortis0low10
Lung Cancer0low20
Lung Diseases0low20
Lung Neoplasms0low20
Lymphatic Diseases0low20
Lymphatism0low20
Lysosomal Enzyme Disorders0low10
Lysosomal Storage Diseases0low10
Manic Depression0medium31
Manic Disorder0medium31
Manic-Depressive Psychosis0medium31
Melancholia0low60
Mood Disorders, Psychotic0low10
Muscle Contraction0low20
Muscle Disorders0low20
Muscle Relaxation0low10
Muscular Diseases0low20
Muscular Dystrophies0low10
Muscular Dystrophy0low10
Myocardial Diseases0low10
Myocardial Diseases, Primary0low10
Myocardial Diseases, Secondary0low10
Myocardiopathies0low10
Myodystrophica0low10
Myodystrophy0low10
Myopathic Conditions0low20
Myopathies0low20
Neoplasms, Lung0low20
Neoplasms, Pulmonary0low20
Nervous System Diseases0low10
Nervous System Disorders0low10
Neuroblastoma0low10
Neurologic Disorders0low10
Neurological Disorders0low10
Neurosis, Depressive0low60
Nonorganic Insomnia0medium11
Ocular Headache0medium11
Orthostatic Headache0medium11
Pain0low10
Pain, Burning0low10
Pain, Crushing0low10
Pain, Migratory0low10
Pain, Radiating0low10
Pain, Splitting0low10
Periorbital Headache0medium11
Postmortem Changes0low10
Pregnancy0low20
Prenatal Exposure Delayed Effects0low20
Primary Insomnia0medium11
Primary Myocardial Diseases0low10
Proptosis0low10
Proteinoses, Pulmonary Alveolar0low10
Proteinosis, Pulmonary Alveolar0low10
Pseudoaphakia0low10
Psychophysiological Insomnia0medium11
Psychoses, Affective0low10
Psychoses, Drug0low10
Psychoses, Manic-Depressive0medium31
Psychoses, Substance-Induced0low10
Psychoses, Toxic0low10
Psychosis, Manic-Depressive0medium31
Psychotic Affective Disorders0low10
Psychotic Mood Disorders0low10
Pulmonary Alveolar Proteinoses0low10
Pulmonary Alveolar Proteinosis0low10
Pulmonary Cancer0low20
Pulmonary Disease0low20
Pulmonary Diseases0low20
Pulmonary Edema0low10
Pulmonary Edemas0low10
Pulmonary Fibroses0low20
Pulmonary Fibrosis0low20
Pulmonary Neoplasms0low20
Reactive Disorders0low20
Rebound Insomnia0medium11
Retinal Diseases0low10
Retro-Ocular Headache0medium11
Secondary Insomnia0medium11
Secondary Myocardial Diseases0low10
Senile Paranoid Dementia0low10
Sharp Headache0medium11
Side Effects of Drugs0low20
Sleep Initiation and Maintenance Disorders0medium11
Sleep Initiation Dysfunction0medium11
Sleeplessness0medium11
Status Lymphaticus0low20
Substance Withdrawal Syndrome0low10
Substance-Induced Psychoses0low10
Sudden Death0low10
Suffering, Physical0low10
Testicular Diseases0low10
Throbbing Headache0medium11
Thyroid Diseases0low10
Toxic Psychoses0low10
Toxicity, Drug0low20
Transient Insomnia0medium11
Transient Situational Disturbance0low20
Unilateral Headache0medium11
Unipolar Depression0low60
Vascular Diseases0low10
Ventricular Fibrillation0low10
Vertex Headache0medium11
Wet Lung0low10
Withdrawal Symptoms0low10

Research Highlights

Safety/Toxicity (3)

ArticleYear
Effects of 2-deoxy-D-glucose on methamphetamine-induced dopamine and serotonin neurotoxicity.
Journal of neurochemistry, Volume: 70, Issue: 1		1998
Long-lasting dopamine receptor up-regulation in amphetamine-treated rats following amphetamine neurotoxicity.
Pharmacology, biochemistry, and behavior, Volume: 40, Issue: 4		1991
Protection against amphetamine-induced neurotoxicity toward striatal dopamine neurons in rodents by LY274614, an excitatory amino acid antagonist.
Neuropharmacology, Volume: 31, Issue: 10		1992
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Long-term Use (17)

ArticleYear
Experimental lipidosis of the inner ear.
Archives of oto-rhino-laryngology, Volume: 229, Issue: 3-4		1980
Differential actions of mianserin and iprindole on the sensitivity of cortical neurons to noradrenaline: effect of chronic treatment.
European journal of pharmacology, Jul-10, Volume: 72, Issue: 4		1981
Atypical antidepressant drugs - psychopharmacological profile and mechanism of action.
Pharmacopsychiatria, Volume: 15, Issue: 1		1982
Changes in amphetamine-induced anorexia and stereotypy during chronic treatment with antidepressant drugs.
European journal of pharmacology, Mar-02, Volume: 98, Issue: 3-4		1984
Antidepressant drugs with varying pharmacological profiles alter rat pineal beta adrenergic-mediated function.
The Journal of pharmacology and experimental therapeutics, Volume: 228, Issue: 3		1984
Sensitivity in vivo of central alpha 2- and opiate receptors after chronic treatment with various antidepressants.
Journal of neural transmission, Volume: 54, Issue: 1-2		1982
Role of neuronal signal input in the down-regulation of central noradrenergic receptor function by antidepressant drugs.
Journal of neurochemistry, Volume: 39, Issue: 1		1982
Alpha 2-adrenoreceptors on human platelets: selective labelling by [3H]clonidine and [3H]yohimbine and competitive inhibition by antidepressant drugs.
European journal of pharmacology, Sep-24, Volume: 74, Issue: 4		1981
Brain monoamine oxidase activity after in vivo-chronic iprindole treatment.
Pharmacology, biochemistry, and behavior, Volume: 15, Issue: 6		1981
Effects of antidepressant drugs on the behavior of olfactory bulbectomized and sham-operated rats.
Behavioral neuroscience, Volume: 100, Issue: 2		1986
The effects of imipramine and iprindole on the metabolism of octopamine in the rat.
Neuropharmacology, Volume: 24, Issue: 8		1985
Regulation of high- and low-affinity [3H]imipramine recognition sites in rat brain by chronic treatment with antidepressants.
European journal of pharmacology, Jun-19, Volume: 138, Issue: 2		1987
Chronic antidepressant treatment reduces central beta-adrenoceptor sensitivity in a behavioural test.
European journal of pharmacology, Aug-07, Volume: 127, Issue: 1-2		1986
Agonist interactions with beta-adrenergic receptors following chronic administration of desipramine or the atypical antidepressants, iprindole and mianserin.
Journal of receptor research, Volume: 5, Issue: 5-6		1985
Chronic electroconvulsive treatment augments coupling of the GTP-binding protein Gs to the catalytic moiety of adenylyl cyclase in a manner similar to that seen with chronic antidepressant drugs.
Journal of neurochemistry, Volume: 56, Issue: 1		1991
A possible common mechanism of action of antidepressant treatments: reduction in the sensitivity of the noradrenergic cyclic AMP gererating system in the rat limbic forebrain.
Naunyn-Schmiedeberg's archives of pharmacology, Volume: 293, Issue: 2		1976
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Dosage (4)

ArticleYear
3H-mepyramine binding in various regions of rat brain following chronic treatment with different classes of antidepressant drugs.
Progress in neuro-psychopharmacology & biological psychiatry, Volume: 6, Issue: 4-6		1982
Brain monoamine oxidase activity after in vivo-chronic iprindole treatment.
Pharmacology, biochemistry, and behavior, Volume: 15, Issue: 6		1981
5-Hydroxytryptamine-stimulated inositol phospholipid hydrolysis in rat cerebral cortex slices: pharmacological characterization and effects of antidepressants.
The Journal of pharmacology and experimental therapeutics, Volume: 233, Issue: 2		1985
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]