Page last updated: 2024-09-24

aluminum lactate

Description

aluminum lactate: RN given refers to compound with unknown number of aluminum atoms [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID16683018
CHEBI ID31196
SCHEMBL ID21126
MeSH IDM0272306

Synonyms (37)

Synonym
einecs 242-670-9
aluminium, tris(2-(hydroxy-kappao)propanoato-kappao)-
aluminium-(rs)-lactat
2500f
aluminum, tris(2-hydroxypropanoato-o(sup 1),o(sup 2))-
aluminium, tris(lactato)-
aluminum, tris(2-hydroxypropanoate-o1,o2)-
aluminum lactate (al(o3c3h5)3)
aluminium lacticum
tris(2-hydroxypropanoato-o(sup 1),o(sup 2))aluminum
aluminum, tris(2-hydroxypropanoato)-
ccris 3464
aluminum lactate
tris(2-hydroxypropanoato)aluminum
tris(lactato)aluminium
aluminium trilactate
tris[2-(hydroxy-kappao)propanoato-kappao]aluminium
tris(2-hydroxypropanoato)aluminium
CHEBI:31196
aluminum tris(alpha-hydroxypropionate)
18917-91-4
D01424
aluminum lactate (jan)
ec 242-670-9
aluminum lactate [jan]
unii-v797h4gg0z
aluminum, tris(2-hydroxypropanoato-o1,o2)-
SCHEMBL21126
mfcd20529175
SR-01000944361-1
sr-01000944361
bis(2-hydroxypropanoyloxy)alumanyl 2-hydroxypropanoate
tris(2-hydroxypropanoyloxy)aluminum
bis[[(2r)-2-hydroxypropanoyl]oxy]alumanyl (2r)-2-hydroxypropanoate
Q27094631
2500f; aluminum tris(alpha-hydroxypropionate); lohtragon al 250
aluminum lactate, min. 95%

Drug Classes (2)

ClassDescription
aluminium coordination entity
lactate saltAny organic salt that has lactate as the cation.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (54)

TimeframeStudies, This Drug (%)All Drugs %
pre-19903 (5.56)18.7374
1990's8 (14.81)18.2507
2000's26 (48.15)29.6817
2010's11 (20.37)24.3611
2020's6 (11.11)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials6 (10.53%)5.53%
Reviews1 (1.75%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other50 (87.72%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research Highlights

Safety/Toxicity (5)

ArticleYear
Ginkgo biloba attenuates aluminum lactate-induced neurotoxicity in reproductive senescent female rats: behavioral, biochemical, and histopathological study.
Environmental science and pollution research international, Volume: 26, Issue: 26
2019
Disruption of neuronal calcium homeostasis after chronic aluminium toxicity in rats.
Basic & clinical pharmacology & toxicology, Volume: 96, Issue: 2
2005
Ligand specific effects on aluminum incorporation and toxicity in neurons and astrocytes.
Brain research, Sep-22, Volume: 877, Issue: 2
2000
Aluminum toxicity in a molluscan neuron: effects of counterions.
Journal of toxicology and environmental health. Part A, Feb-25, Volume: 59, Issue: 4
2000
Short-term oral 3-hydroxypyridin-4-one dosing increases aluminum excretion and partially reverses aluminum-induced toxicity in the rabbit independent of chelator lipophilicity.
Drug metabolism and disposition: the biological fate of chemicals, Volume: 25, Issue: 2
1997
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Long-term Use (2)

ArticleYear
Urinary concentrating mechanism and Aquaporin-2 abundance in rats chronically treated with aluminum lactate.
Toxicology, Jun-15, Volume: 223, Issue: 3
2006
Effects of aluminum on phosphate metabolism in rats: a possible interaction with vitamin D3 renal production.
Archives of toxicology, Volume: 78, Issue: 11
2004
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioavailability (1)

ArticleYear
Bioavailability and intestinal absorption of aluminum in rats: effects of aluminum compounds and some dietary constituents.
Biological trace element research, Volume: 76, Issue: 1
2000
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Dosage (8)

ArticleYear
Aluminium effects on thyroid gland function: iodide uptake, hormone biosynthesis and secretion.
Journal of inorganic biochemistry, Volume: 105, Issue: 11
2011
Chronic exposure to low levels of aluminum alters cerebral cell signaling in response to acute MPTP administration.
Toxicology and industrial health, Volume: 23, Issue: 9
2007
Evaluation of the effects of aluminium, ethanol and their combination on rat brain synaptosomal integral proteins in vitro and after 90-day oral exposure.
Archives of toxicology, Volume: 78, Issue: 5
2004
A model of aluminum exposure associated with lipid peroxidation in rat brain.
Biological trace element research,Winter, Volume: 96, Issue: 1-3
2003
Decrease of glial fibrillary acidic protein in rat frontal cortex following aluminum treatment.
Journal of neurochemistry, Volume: 73, Issue: 4
1999
Effect of the size of an oral dose of aluminium on the relative importance of biliary v. urinary aluminium excretion in conscious rats.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, Volume: 36, Issue: 6
1998
Kinetics of aluminum disposition after ingestion of low to moderate pharmacological doses of aluminum.
Toxicology, Mar-13, Volume: 126, Issue: 2
1998
Short-term oral 3-hydroxypyridin-4-one dosing increases aluminum excretion and partially reverses aluminum-induced toxicity in the rabbit independent of chelator lipophilicity.
Drug metabolism and disposition: the biological fate of chemicals, Volume: 25, Issue: 2
1997
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]