Page last updated: 2024-10-25

clidinium and Neuroblastoma

clidinium has been researched along with Neuroblastoma in 3 studies

clidinium: see also record for clidinium compounds; RN given refers to cpd without isomeric designation
clidinium : The ester resulting from formal condensation of benzilic acid and 3-hydroxy-1-methyl-1-azoniabicyclo[2.2.2]octane. It is used, generally as the bromide, for the symptomatic treatment of peptic ulcer disease and also to help relieve abdominal or stomach spasms or cramps due to colicky abdominal pain, diverticulitis, and irritable bowel syndrome.

Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)

Research Excerpts

ExcerptRelevanceReference
"The binding of [3H]pirenzepine to a human neuroblastoma cell line (SH-SY5Y) and its correlation with hydrolysis of phosphatidylinositols were characterized."7.67The intact human neuroblastoma cell (SH-SY5Y) exhibits high-affinity [3H]pirenzepine binding associated with hydrolysis of phosphatidylinositols. ( Lui, GK; Mei, L; Roeske, WR; Serra, M; Watson, M; Yamamura, HI, 1988)
"The binding of [3H]pirenzepine to a human neuroblastoma cell line (SH-SY5Y) and its correlation with hydrolysis of phosphatidylinositols were characterized."3.67The intact human neuroblastoma cell (SH-SY5Y) exhibits high-affinity [3H]pirenzepine binding associated with hydrolysis of phosphatidylinositols. ( Lui, GK; Mei, L; Roeske, WR; Serra, M; Watson, M; Yamamura, HI, 1988)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19902 (66.67)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Waelbroeck, M1
Tastenoy, M1
Camus, J1
Christophe, J1
Fisher, SK1
Serra, M1
Mei, L1
Roeske, WR1
Lui, GK1
Watson, M1
Yamamura, HI1

Other Studies

3 other studies available for clidinium and Neuroblastoma

ArticleYear
Binding kinetics of quinuclidinyl benzilate and methyl-quinuclidinyl benzilate enantiomers at neuronal (M1), cardiac (M2), and pancreatic (M3) muscarinic receptors.
    Molecular pharmacology, 1991, Volume: 40, Issue:3

    Topics: Animals; Binding, Competitive; Humans; In Vitro Techniques; Kinetics; Myocardium; Neuroblastoma; Pan

1991
Recognition of muscarinic cholinergic receptors in human SK-N-SH neuroblastoma cells by quaternary and tertiary ligands is dependent upon temperature, cell integrity, and the presence of agonists.
    Molecular pharmacology, 1988, Volume: 33, Issue:4

    Topics: Atropine; Binding, Competitive; Carbachol; Humans; Kinetics; Ligands; N-Methylscopolamine; Neuroblas

1988
The intact human neuroblastoma cell (SH-SY5Y) exhibits high-affinity [3H]pirenzepine binding associated with hydrolysis of phosphatidylinositols.
    Journal of neurochemistry, 1988, Volume: 50, Issue:5

    Topics: Atropine; Binding, Competitive; Humans; Hydrolysis; Kinetics; Neuroblastoma; Phosphatidylinositols;

1988