chlorpyrifos has been researched along with Neuroblastoma in 13 studies
Chlorpyrifos: An organothiophosphate cholinesterase inhibitor that is used as an insecticide and as an acaricide.
chlorpyrifos : An organic thiophosphate that is O,O-diethyl hydrogen phosphorothioate in which the hydrogen of the hydroxy group has been replaced by a 3,5,6-trichloropyridin-2-yl group.
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this sense, the rise of cyanobacterial blooms, which release secondary metabolites with toxic properties, and the global use of pesticides for agricultural purposes have a negative impact on ecosystems." | 5.91 | Toxic effects of the cylindrospermopsin and chlorpyrifos combination on the differentiated SH-SY5Y human neuroblastoma cell line. ( Cameán, AM; Gutiérrez-Praena, D; Hinojosa, MG; Jos, Á; López, S; Moreno, FJ; Prieto, AI, 2023) |
| "Thus, we treated the human neuroblastoma SH-SY5Y cells with ISO (0." | 5.72 | A Pretreatment with Isoorientin Attenuates Redox Disruption, Mitochondrial Impairment, and Inflammation Caused by Chlorpyrifos in a Dopaminergic Cell Line: Involvement of the Nrf2/HO-1 Axis. ( Brasil, FB; Dall'Oglio, EL; de Almeida, FJS; de Oliveira, MR; Luckachaki, MD, 2022) |
| "Previous work in our laboratory has shown that sub-lethal concentrations (1-10 μM) of chlorpyrifos (CPF), diazinon (DZ) and diazinon oxon (DZO) inhibit the outgrowth of axon-like neurites in differentiating mouse N2a neuroblastoma cells concomitant with altered levels and/or phosphorylation state of axonal cytoskeleton and growth-associated proteins." | 3.77 | Effects of sub-lethal neurite outgrowth inhibitory concentrations of chlorpyrifos oxon on cytoskeletal proteins and acetylcholinesterase in differentiating N2a cells. ( Flaskos, J; Hargreaves, AJ; Harris, W; Nikolaidis, E; Sachana, M, 2011) |
| " NB2a neuroblastoma cells were induced to differentiate in the presence of the OPs diazinon and chlorpyrifos, in combination with a commercial formulation (identified as Commercial Formulation 1) of the compounds and, independently, the components of that formulation." | 3.71 | Interactions between pesticides and components of pesticide formulations in an in vitro neurotoxicity test. ( Axelrad, JC; Howard, CV; McLean, WG, 2002) |
| "05% bromine solution or uninduced rat liver microsomes (RLM) resulted in production of the corresponding oxygen analogs of these OP compounds and markedly increased esterase inhibition in SH-SY5Y human neuroblastoma cells." | 3.70 | Comparison of two in vitro activation systems for protoxicant organophosphorous esterase inhibitors. ( Barber, D; Correll, L; Ehrich, M, 1999) |
| "Thus, we treated the human neuroblastoma SH-SY5Y cells with ISO (0." | 1.72 | A Pretreatment with Isoorientin Attenuates Redox Disruption, Mitochondrial Impairment, and Inflammation Caused by Chlorpyrifos in a Dopaminergic Cell Line: Involvement of the Nrf2/HO-1 Axis. ( Brasil, FB; Dall'Oglio, EL; de Almeida, FJS; de Oliveira, MR; Luckachaki, MD, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (15.38) | 18.2507 |
| 2000's | 2 (15.38) | 29.6817 |
| 2010's | 4 (30.77) | 24.3611 |
| 2020's | 5 (38.46) | 2.80 |
| Authors | Studies |
|---|---|
| Delic, V | 1 |
| Karp, J | 1 |
| Klein, J | 1 |
| Stalnaker, KJ | 1 |
| Murray, KE | 1 |
| Ratliff, WA | 1 |
| Myers, CE | 1 |
| Beck, KD | 1 |
| Citron, BA | 1 |
| Brasil, FB | 1 |
| de Almeida, FJS | 1 |
| Luckachaki, MD | 1 |
| Dall'Oglio, EL | 1 |
| de Oliveira, MR | 1 |
| Parween, F | 1 |
| Sarker, A | 1 |
| Gupta, RD | 1 |
| Hinojosa, MG | 1 |
| Gutiérrez-Praena, D | 1 |
| López, S | 1 |
| Prieto, AI | 1 |
| Moreno, FJ | 1 |
| Jos, Á | 1 |
| Cameán, AM | 1 |
| Almami, IS | 1 |
| Aldubayan, MA | 1 |
| Felemban, SG | 1 |
| Alyamani, N | 1 |
| Howden, R | 1 |
| Robinson, AJ | 1 |
| Pearson, TDZ | 1 |
| Boocock, D | 1 |
| Algarni, AS | 1 |
| Garner, AC | 1 |
| Griffin, M | 1 |
| Bonner, PLR | 1 |
| Hargreaves, AJ | 2 |
| Raszewski, G | 1 |
| Lemieszek, MK | 1 |
| Łukawski, K | 1 |
| Juszczak, M | 1 |
| Rzeski, W | 1 |
| Park, JH | 1 |
| Ko, J | 1 |
| Park, YS | 1 |
| Park, J | 1 |
| Hwang, J | 1 |
| Koh, HC | 1 |
| Flaskos, J | 1 |
| Nikolaidis, E | 1 |
| Harris, W | 1 |
| Sachana, M | 1 |
| Huff, RA | 1 |
| Abou-Donia, MB | 1 |
| Barber, D | 1 |
| Correll, L | 1 |
| Ehrich, M | 2 |
| Barber, DS | 1 |
| Axelrad, JC | 1 |
| Howard, CV | 1 |
| McLean, WG | 1 |
| Trillo, MA | 1 |
| Cid, MA | 1 |
| Martínez, MA | 1 |
| Page, JE | 1 |
| Esteban, J | 1 |
| Úbeda, A | 1 |
13 other studies available for chlorpyrifos and Neuroblastoma
| Article | Year |
|---|---|
Pyridostigmine bromide, chlorpyrifos, and DEET combined Gulf War exposure insult depresses mitochondrial function in neuroblastoma cells.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Cell Line, Tumor; Chlorpyrifos; DEET; Humans; Mice; Mito | 2021 |
A Pretreatment with Isoorientin Attenuates Redox Disruption, Mitochondrial Impairment, and Inflammation Caused by Chlorpyrifos in a Dopaminergic Cell Line: Involvement of the Nrf2/HO-1 Axis.
Topics: Cell Line, Tumor; Cell Survival; Chlorpyrifos; Heme Oxygenase-1; Humans; Inflammation; Luteolin; Mit | 2022 |
Chlorpyrifos and parathion regulate oxidative stress differentially through the expression of paraoxonase 2 in human neuroblastoma cell.
Topics: Acetylcholinesterase; Aryldialkylphosphatase; Chlorpyrifos; Humans; Insecticides; Neuroblastoma; Oxi | 2022 |
Toxic effects of the cylindrospermopsin and chlorpyrifos combination on the differentiated SH-SY5Y human neuroblastoma cell line.
Topics: Acetylcholinesterase; Cell Differentiation; Cell Line, Tumor; Chlorpyrifos; Ecosystem; Humans; Neuro | 2023 |
Neurite outgrowth inhibitory levels of organophosphates induce tissue transglutaminase activity in differentiating N2a cells: evidence for covalent adduct formation.
Topics: Amines; Animals; Biotin; Cell Differentiation; Cell Line, Tumor; Cell Survival; Chlorpyrifos; GTP-Bi | 2020 |
Chlorpyrifos and cypermethrin induce apoptosis in human neuroblastoma cell line SH-SY5Y.
Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Cell Line, Tumor; Chlorpyrifos; Dose-Response Relationsh | 2015 |
Clearance of Damaged Mitochondria Through PINK1 Stabilization by JNK and ERK MAPK Signaling in Chlorpyrifos-Treated Neuroblastoma Cells.
Topics: Cell Line, Tumor; Chlorpyrifos; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Extrace | 2017 |
Effects of sub-lethal neurite outgrowth inhibitory concentrations of chlorpyrifos oxon on cytoskeletal proteins and acetylcholinesterase in differentiating N2a cells.
Topics: Acetylcholinesterase; Animals; Blotting, Western; Brain Neoplasms; Cell Culture Techniques; Cell Dif | 2011 |
In vitro effect of chlorpyrifos oxon on muscarinic receptors and adenylate cyclase.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclase | 1995 |
Comparison of two in vitro activation systems for protoxicant organophosphorous esterase inhibitors.
Topics: Animals; Bromine; Carboxylic Ester Hydrolases; Chlorpyrifos; Cholinesterase Inhibitors; Chromatograp | 1999 |
Esterase inhibition in SH-SY5Y human neuroblastoma cells following exposure to organophosphorus compounds for 28 days.
Topics: Acetylcholinesterase; Carboxylic Ester Hydrolases; Chlorpyrifos; Drug Evaluation, Preclinical; Human | 2001 |
Interactions between pesticides and components of pesticide formulations in an in vitro neurotoxicity test.
Topics: Animals; Biological Assay; Cell Line; Chlorpyrifos; Chrysanthemum cinerariifolium; Diazinon; Drug Sy | 2002 |
Cytostatic response of NB69 cells to weak pulse-modulated 2.2 GHz radar-like signals.
Topics: Cell Cycle; Cell Line, Tumor; Cell Survival; Humans; Neuroblastoma; Radar; Radiation Dosage; Radiofr | 2011 |