halocynthiaxanthin and Neuroblastoma

halocynthiaxanthin has been researched along with Neuroblastoma* in 1 studies

Other Studies

1 other study(ies) available for halocynthiaxanthin and Neuroblastoma

Article	Year
Anti-neoplastic effect of halocynthiaxanthin, a metabolite of fucoxanthin. Anti-cancer drugs, 1992, Volume: 3, Issue:5 We have reported that fucoxanthin, a natural carotenoid, inhibited the growth of human neuroblastoma GOTO cells. In the present study, we show that a metabolite of fucoxanthin, halocynthiaxanthin, which is isolated from sea squirt Halocynthia roretzi, has a more potent inhibitory effect. Halocynthiaxanthin (5 micrograms/ml) caused complete suppression of GOTO cell proliferation, whereas fucoxanthin reduced the growth rate by only 88.8% compared with the control, at day 2 after the drug treatment. Furthermore, halocynthiaxanthin also inhibited the growth of other human malignant tumor cells. Thus halocynthiaxanthin seems to be a promising anti-neoplastic agent. Topics: Antineoplastic Agents; Carotenoids; Cell Division; Colonic Neoplasms; DNA, Neoplasm; Food; Gene Expression; Genes, myc; HeLa Cells; Humans; Kinetics; Neoplasm Proteins; Neuroblastoma; Pancreatic Neoplasms; RNA, Neoplasm; Stomach Neoplasms; Tumor Cells, Cultured; Xanthophylls	1992

Article

Year

Anti-neoplastic effect of halocynthiaxanthin, a metabolite of fucoxanthin.

Anti-cancer drugs, 1992, Volume: 3, Issue:5

We have reported that fucoxanthin, a natural carotenoid, inhibited the growth of human neuroblastoma GOTO cells. In the present study, we show that a metabolite of fucoxanthin, halocynthiaxanthin, which is isolated from sea squirt Halocynthia roretzi, has a more potent inhibitory effect. Halocynthiaxanthin (5 micrograms/ml) caused complete suppression of GOTO cell proliferation, whereas fucoxanthin reduced the growth rate by only 88.8% compared with the control, at day 2 after the drug treatment. Furthermore, halocynthiaxanthin also inhibited the growth of other human malignant tumor cells. Thus halocynthiaxanthin seems to be a promising anti-neoplastic agent.

Topics: Antineoplastic Agents; Carotenoids; Cell Division; Colonic Neoplasms; DNA, Neoplasm; Food; Gene Expression; Genes, myc; HeLa Cells; Humans; Kinetics; Neoplasm Proteins; Neuroblastoma; Pancreatic Neoplasms; RNA, Neoplasm; Stomach Neoplasms; Tumor Cells, Cultured; Xanthophylls

1992