Page last updated: 2024-12-11

pbox-6

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

PBOX-6: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID9865511
CHEMBL ID5186534
SCHEMBL ID5322209
MeSH IDM0377238

Synonyms (19)

Synonym
pyrrolo-1,5-benzoxazepine-6
carbamic acid, n,n-dimethyl-, 6-(1-naphthalenyl)pyrrolo(2,1-d)(1,5)benzoxazepin-7-yl ester
pbox-6
290814-68-5
carbamic acid, dimethyl-, 6-(1-naphthalenyl)pyrrolo(2,1-d)(1,5)benzoxazepin-7-yl ester
IN93MQ497D ,
SCHEMBL5322209
unii-in93mq497d
pbox-6, >=98% (hplc)
7-[(n,n-dimethylcarbamoyl)oxy]-6-(naphth-1-yl)pyrrolo[2,1-d][1,5]benzoxazepine
CHEMBL5186534
6-(naphthalen-1-yl)benzo[b]pyrrolo[1,2-d][1,4]oxazepin-7-yl dimethylcarbamate
pbox 6
HY-U00446
CS-0035400
(6-naphthalen-1-ylpyrrolo[2,1-d][1,5]benzoxazepin-7-yl) n,n-dimethylcarbamate
Q27280810
MS-26682
AKOS040742367
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (3)

Assay IDTitleYearJournalArticle
AID1906530Cytotoxicity against human Ca9-22 cells assessed as reduction in cell viability measured after 48 hrs by alamar blue viability assay2022European journal of medicinal chemistry, May-05, Volume: 235Design and synthesis of multifunctional microtubule targeting agents endowed with dual pro-apoptotic and anti-autophagic efficacy.
AID1906522Induction of Pro-apoptosis in human HL-60 cells assessed as increase in apoptotic cells at 10 uM after 48 hrs by Annexin-V/PI-staining based flow cytometry2022European journal of medicinal chemistry, May-05, Volume: 235Design and synthesis of multifunctional microtubule targeting agents endowed with dual pro-apoptotic and anti-autophagic efficacy.
AID1906529Cytotoxicity against human SCC-4 cells assessed as reduction in cell viability measured after 48 hrs by alamar blue viability assay2022European journal of medicinal chemistry, May-05, Volume: 235Design and synthesis of multifunctional microtubule targeting agents endowed with dual pro-apoptotic and anti-autophagic efficacy.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (20)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's10 (50.00)29.6817
2010's9 (45.00)24.3611
2020's1 (5.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 16.54

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index16.54 (24.57)
Research Supply Index3.04 (2.92)
Research Growth Index4.40 (4.65)
Search Engine Demand Index10.37 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (16.54)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other20 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]