Page last updated: 2024-12-11
pbox-6
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Description
PBOX-6: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
ID Source | ID |
---|---|
PubMed CID | 9865511 |
CHEMBL ID | 5186534 |
SCHEMBL ID | 5322209 |
MeSH ID | M0377238 |
Synonyms (19)
Synonym |
---|
pyrrolo-1,5-benzoxazepine-6 |
carbamic acid, n,n-dimethyl-, 6-(1-naphthalenyl)pyrrolo(2,1-d)(1,5)benzoxazepin-7-yl ester |
pbox-6 |
290814-68-5 |
carbamic acid, dimethyl-, 6-(1-naphthalenyl)pyrrolo(2,1-d)(1,5)benzoxazepin-7-yl ester |
IN93MQ497D , |
SCHEMBL5322209 |
unii-in93mq497d |
pbox-6, >=98% (hplc) |
7-[(n,n-dimethylcarbamoyl)oxy]-6-(naphth-1-yl)pyrrolo[2,1-d][1,5]benzoxazepine |
CHEMBL5186534 |
6-(naphthalen-1-yl)benzo[b]pyrrolo[1,2-d][1,4]oxazepin-7-yl dimethylcarbamate |
pbox 6 |
HY-U00446 |
CS-0035400 |
(6-naphthalen-1-ylpyrrolo[2,1-d][1,5]benzoxazepin-7-yl) n,n-dimethylcarbamate |
Q27280810 |
MS-26682 |
AKOS040742367 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Bioassays (3)
Assay ID | Title | Year | Journal | Article |
---|---|---|---|---|
AID1906530 | Cytotoxicity against human Ca9-22 cells assessed as reduction in cell viability measured after 48 hrs by alamar blue viability assay | 2022 | European journal of medicinal chemistry, May-05, Volume: 235 | Design and synthesis of multifunctional microtubule targeting agents endowed with dual pro-apoptotic and anti-autophagic efficacy. |
AID1906522 | Induction of Pro-apoptosis in human HL-60 cells assessed as increase in apoptotic cells at 10 uM after 48 hrs by Annexin-V/PI-staining based flow cytometry | 2022 | European journal of medicinal chemistry, May-05, Volume: 235 | Design and synthesis of multifunctional microtubule targeting agents endowed with dual pro-apoptotic and anti-autophagic efficacy. |
AID1906529 | Cytotoxicity against human SCC-4 cells assessed as reduction in cell viability measured after 48 hrs by alamar blue viability assay | 2022 | European journal of medicinal chemistry, May-05, Volume: 235 | Design and synthesis of multifunctional microtubule targeting agents endowed with dual pro-apoptotic and anti-autophagic efficacy. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Research
Studies (20)
Timeframe | Studies, This Drug (%) | All Drugs % |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 10 (50.00) | 29.6817 |
2010's | 9 (45.00) | 24.3611 |
2020's | 1 (5.00) | 2.80 |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 16.54
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (16.54) All Compounds (24.57) |
Study Types
Publication Type | This drug (%) | All Drugs (%) |
---|---|---|
Trials | 0 (0.00%) | 5.53% |
Reviews | 0 (0.00%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 20 (100.00%) | 84.16% |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |