Compounds > 3beta-(n-(n',n'-dimethylaminoethane)carbamoyl)cholesterol
Page last updated: 2024-09-24

3beta-(n-(n',n'-dimethylaminoethane)carbamoyl)cholesterol

Description

3-(N-(N',N'-dimethylaminoethane)carbamoyl)cholesterol: used to prepare sonicated liposomes [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID115234
SCHEMBL ID5884196
MeSH IDM0192259

Synonyms (26)

Synonym
dc-chol
3-(n-(n',n'-dimethylaminoethane)carbamoyl)cholesterol
137056-72-5
3beta-(n-(n',n'-dimethylaminoethane)carbamoyl)cholesterol
cholest-5-en-3-ol (3beta)-, (2-(dimethylamino)ethyl)carbamate
dac 30
dac-30
cholesteryl n-(2-dimethylaminoethyl)carbamate
3beta-[n-(n',n'-dimethylaminoethane)-carbamoyl]cholesterol
AKOS025294423
SCHEMBL5884196
(3s,8s,9s,10r,13r,14s,17r)-10,13-dimethyl-17-((r)-6-methylheptan-2-yl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1h-cyclopenta[a]phenanthren-3-yl (2-(dimethylamino)ethyl)carbamate
J-006956
3beta-{n-[2-(dimethylamino)ethyl]carbamoyl}cholesterol
3-beta-cholest-5-en-3-yl [2-(dimethylamino)ethyl]carbamate
NCGC00485229-01
3beta-[n-(n',n'-dimethylaminoethane)- carbamoy1]cholesterol
HIHOWBSBBDRPDW-PTHRTHQKSA-N
3beta-[n-(n',n'-dimethylaminoethane)carbamoyl]cholesterol
cholest-5-en-3-yl hydrogen [2-(dimethylamino)ethyl]carbonimidate
DTXSID80929700
3|a-[n-(n',n'-dimethylaminoethane)-carbamoyl]cholesterol
o-[(n,n-dimethylaminoethyl)-carbamoyl]cholesterol
[(3s,8s,9s,10r,13r,14s,17r)-10,13-dimethyl-17-[(2r)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1h-cyclopenta[a]phenanthren-3-yl] n-[2-(dimethylamino)ethyl]carbamate
3 beta -{n-[2-(dimethylamino)ethyl]carbamoyl}cholesterol
cholest-5-en-3-ol (3beta)-, [2-(dimethylamino)ethyl]carbamate

Bioassays (5)

Assay IDTitleYearJournalArticle
AID1296008Cytotoxic Profiling of Annotated Libraries Using Quantitative High-Throughput Screening2020SLAS discovery : advancing life sciences R & D, 01, Volume: 25, Issue:1
Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening.
AID1347160Primary screen NINDS Rhodamine qHTS for Zika virus inhibitors2020Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
AID1346986P-glycoprotein substrates identified in KB-3-1 adenocarcinoma cell line, qHTS therapeutic library screen2019Molecular pharmacology, 11, Volume: 96, Issue:5
A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
AID1346987P-glycoprotein substrates identified in KB-8-5-11 adenocarcinoma cell line, qHTS therapeutic library screen2019Molecular pharmacology, 11, Volume: 96, Issue:5
A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
AID1347159Primary screen GU Rhodamine qHTS for Zika virus inhibitors: Unlinked NS2B-NS3 protease assay2020Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (115)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's32 (27.83)18.2507
2000's43 (37.39)29.6817
2010's37 (32.17)24.3611
2020's3 (2.61)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials4 (3.42%)5.53%
Reviews1 (0.85%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other112 (95.73%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceDescriptionRelationhip StrengthStudiesTrialsClassesRoles
dioleoyl phosphatidylethanolamine[no description available]medium190phosphatidylethanolamine
1,2-dioleoyloxy-3-(trimethylammonium)propane[no description available]medium200
n-(1-(2,3-dioleyloxy)propyl)-n,n,n-trimethylammonium chloride[no description available]medium20
1,2-oleoylphosphatidylcholine[no description available]medium70phosphatidylcholine(1+)
phosphatidylcholines[no description available]medium1301,2-diacyl-sn-glycero-3-phosphocholine
1,2-dielaidoylphosphatidylethanolamine[no description available]medium211
didodecyldimethylammonium[no description available]medium40
3-((3-cholamidopropyl)dimethylammonium)-1-propanesulfonate[no description available]medium101,1-diunsubstituted alkanesulfonate
biliverdine[no description available]medium10
ovalbumin[no description available]medium50
lactic acid[no description available]medium202-hydroxy monocarboxylic acidalgal metabolite;
Daphnia magna metabolite
diphenylhexatriene[no description available]medium20alkatrienefluorochrome
laurdan[no description available]medium20
2-naphthylamine[no description available]medium20naphthylaminecarcinogenic agent
4-heptadecylumbelliferone[no description available]medium10
1,2-dipalmitoyl-3-phosphatidylethanolamine[no description available]medium20
1,2-distearoyllecithin[no description available]medium10
chloroquine[no description available]medium10aminoquinoline;
organochlorine compound;
secondary amino compound;
tertiary amino compound		anticoronaviral agent;
antimalarial;
antirheumatic drug;
autophagy inhibitor;
dermatologic drug
aluminum sulfate[no description available]medium10aluminium sulfate
beta-escin[no description available]medium20
quil a[no description available]medium20
quillaja saponins[no description available]medium20
raloxifene hydrochloride[no description available]medium10hydrochloridebone density conservation agent;
estrogen antagonist;
estrogen receptor modulator
1,2-distearoylphosphatidylethanolamine[no description available]medium10phosphatidylethanolamine zwitterion;
phosphatidylethanolamine		human metabolite
oregon green 488 carboxylic acid[no description available]medium10xanthene dyeepitope;
fluorochrome
1,2-dipalmitoylphosphatidylcholine[no description available]medium30
1,2-didodecanoyl-glycero-3-phosphocholine[no description available]medium10dodecanoate ester;
phosphatidylglycerol
dimethyldioctadecylammonium[no description available]medium20
cyanine dye 3[no description available]medium10
carbocyanines[no description available]medium10cyanine dye;
organic iodide salt		fluorochrome
fluorescein[no description available]medium102-benzofurans;
gamma-lactone;
organic heteropentacyclic compound;
oxaspiro compound;
polyphenol;
xanthene dye		fluorescent dye;
radioopaque medium
oligonucleotides[no description available]medium30
phosphoramide[no description available]medium10
(3-dimyristyloxypropyl)(dimethyl)(hydroxyethyl)ammonium[no description available]medium30
glucose, (beta-d)-isomer[no description available]medium10D-glucopyranoseepitope;
mouse metabolite
spermine[no description available]medium10polyazaalkane;
tetramine		antioxidant;
fundamental metabolite;
immunosuppressive agent
transferrin[no description available]medium20
3,5-dipentadecyloxybenzamidine hydrochloride[no description available]medium10
1-palmitoyl-2-oleoylphosphatidylcholine[no description available]medium20
1-palmitoyl-2-oleoylglycero-3-phosphoserine[no description available]medium103-sn-phosphatidyl-L-serine
isomaltose[no description available]medium10
isomaltotriose[no description available]medium10glucotriose
sucrose[no description available]medium10glycosyl glycosidealgal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
osmolyte;
Saccharomyces cerevisiae metabolite;
sweetening agent
stearylamine[no description available]medium10primary aliphatic aminefilm-forming compound
hirudin[no description available]medium10
sodium azide[no description available]medium10inorganic sodium saltantibacterial agent;
explosive;
mitochondrial respiratory-chain inhibitor;
mutagen
deoxyglucose[no description available]medium10
monensin[no description available]medium10cyclic hemiketal;
monocarboxylic acid;
polyether antibiotic;
spiroketal		antifungal agent;
coccidiostat;
ionophore
1,2-dioleoyl-sn-glycero-3-phosphoglycerol[no description available]medium101,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)
azides[no description available]medium10pseudohalide anionmitochondrial respiratory-chain inhibitor
dicetylphosphate[no description available]medium10dialkyl phosphate
pentetic acid[no description available]medium10pentacarboxylic acidcopper chelator
lipofectamine[no description available]medium60
paclitaxel[no description available]medium10taxane diterpenoid;
tetracyclic diterpenoid		antineoplastic agent;
human metabolite;
metabolite;
microtubule-stabilising agent
mechlorethamine[no description available]medium10nitrogen mustard;
organochlorine compound		alkylating agent
epidermal growth factor[no description available]medium30
glycocholic acid[no description available]medium10bile acid glycine conjugatehuman metabolite
cetyltrimethylammonium ion[no description available]medium10quaternary ammonium ion
fluorouracil[no description available]medium10nucleobase analogue;
organofluorine compound		antimetabolite;
antineoplastic agent;
environmental contaminant;
immunosuppressive agent;
radiosensitizing agent;
xenobiotic
didodecyl n-(alpha-trimethylammonioacetyl)glutamate[no description available]medium10
sphingosine[no description available]medium10sphing-4-eninehuman metabolite;
mouse metabolite
wortmannin[no description available]medium10acetate ester;
cyclic ketone;
delta-lactone;
organic heteropentacyclic compound		anticoronaviral agent;
antineoplastic agent;
autophagy inhibitor;
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor;
geroprotector;
Penicillium metabolite;
radiosensitizing agent
sybr green i[no description available]medium10benzothiazolium ion;
cyanine dye;
quinolines;
tertiary amine		fluorescent dye
edetic acid[no description available]medium10ethylenediamine derivative;
polyamino carboxylic acid;
tetracarboxylic acid		anticoagulant;
antidote;
chelator;
copper chelator;
geroprotector
dimyristoylphosphatidylcholine[no description available]medium101,2-diacyl-sn-glycero-3-phosphocholine;
phosphatidylcholine 28:0;
tetradecanoate ester		antigen;
mouse metabolite
fluorexon[no description available]medium10xanthene dyefluorochrome
erythrosine[no description available]medium10
hexadimethrine bromide[no description available]medium10
lyoniside[no description available]medium10
cytellin[no description available]medium10
firefly luciferin[no description available]medium101,3-thiazolemonocarboxylic acid;
benzothiazoles;
imidothioate		luciferin
glycolipids[no description available]medium10
n-acetylaspartic acid[no description available]medium10N-acetyl-L-amino acid;
N-acyl-L-aspartic acid		antioxidant;
human metabolite;
mouse metabolite;
nutraceutical;
rat metabolite
phenyl acetate[no description available]medium10benzenes;
phenyl acetates
calcium acetate[no description available]medium10calcium saltchelator
aspartic acid[no description available]medium10aspartate family amino acid;
aspartic acid;
L-alpha-amino acid;
proteinogenic amino acid		Escherichia coli metabolite;
mouse metabolite;
neurotransmitter
acetazolamide[no description available]medium10monocarboxylic acid amide;
sulfonamide;
thiadiazoles		anticonvulsant;
diuretic;
EC 4.2.1.1 (carbonic anhydrase) inhibitor
idarubicin[no description available]medium10anthracycline antibiotic;
deoxy hexoside;
monosaccharide derivative
ConditionIndicatedRelationship StrengthStudiesTrials
ACY2 Deficiency0low10
Aminoacylase 2 Deficiency0low10
Anasarca0low10
Angiogenesis, Pathologic0low10
Angiogenesis, Pathological0low10
ASP Deficiency0low10
ASPA Deficiency0low10
Aspartoacylase Deficiency0low10
B16 Melanoma0low10
Benign Neoplasms0low10
Benign Neoplasms, Brain0low20
Brain Cancer0low20
Brain Edema0low10
Brain Metastases0low20
Brain Neoplasm, Primary0low20
Brain Neoplasms0low20
Brain Neoplasms, Benign0low20
Brain Neoplasms, Malignant0low20
Brain Neoplasms, Malignant, Primary0low20
Brain Neoplasms, Primary Malignant0low20
Brain Swelling0low10
Brain Tumor, Primary0low20
Brain Tumor, Recurrent0low20
Brain Tumors0low20
Breast Cancer0medium21
Breast Carcinoma0medium21
Breast Neoplasms0medium21
Breast Tumors0medium21
Canavan Disease0low10
Canavan Disease, Familial Form0low10
Canavan Disease, Infantile0low10
Canavan Disease, Juvenile0low10
Canavan Disease, Neonatal0low10
Canavan Disease, Sporadic Form0low10
Canavan Disease, Type I0low10
Canavan Disease, Type II0low10
Canavan Disease, Type III0low10
Canavan-van Bogaert-Bertrand Disease0low10
Cancer0low10
Cancer of Brain0low20
Cancer of Breast0medium21
Cancer of Head0medium21
Cancer of Head and Neck0medium21
Cancer of Liver0low10
Cancer of Lung0low20
Cancer of Neck0medium21
Cancer of Ovary0medium31
Cancer of Prostate0low10
Cancer of the Brain0low20
Cancer of the Breast0medium21
Cancer of the Head0medium21
Cancer of the Head and Neck0medium21
Cancer of the Liver0low10
Cancer of the Lung0low20
Cancer of the Neck0medium21
Cancer of the Ovary0medium31
Cancer of the Prostate0low10
Cancer, Hepatocellular0low10
Carcinoma, Epidermoid0medium11
Carcinoma, Planocellular0medium11
Carcinoma, Squamous0medium11
Carcinoma, Squamous Cell0medium11
Central Nervous System Disease0low10
Central Nervous System Diseases0low10
Central Nervous System Disorder0low10
Central Nervous System Disorders0low10
Centrala nervsystemets sjukdomar@sv0low10
Cerebral Edema0low10
Cerebral Edema, Cytotoxic0low10
Cerebral Edema, Vasogenic0low10
Choroby OUN@pl0low10
CNS Disease0low10
CNS Diseases0low10
Congenital Zika Syndrome0low10
Congenital Zika Virus Infection0low10
Cystic Fibrosis0medium31
Cystic Fibrosis of Pancreas0medium31
Cytomegalovirus0low10
Cytotoxic Brain Edema0low10
Cytotoxic Cerebral Edema0low10
Deficiency Disease, Aspartoacylase0low10
Disease Models, Animal0low30
Doenu00E7as do Sistema Nervoso Central@pt0low10
Dropsy0low10
Edema0low10
Embryopathies0low10
Enfermedades del Sistema Nervioso Central@es0low10
Experimental Hepatoma0low20
Experimental Hepatomas0low20
Experimental Liver Neoplasms0low20
Experimental Melanoma0low10
Experimental Melanomas0low10
Experimental Neoplasms0low10
Familial Form of Canavan Disease0low10
Fetal Diseases0low10
Fever, Zika0low10
Fibrocystic Disease of Pancreas0medium31
Glial Cell Tumors0low30
Glioma0low30
Harding Passey Melanoma0low10
Head and Neck Cancer0medium21
Head and Neck Neoplasm0medium21
Head and Neck Neoplasms0medium21
Head Cancer0medium21
Head Neoplasm0medium21
Head Neoplasms0medium21
Head, Neck Neoplasms0medium21
Helicobacter Infections0low10
Hepatic Cancer0low10
Hepatic Neoplasms0low10
Hepatoblastoma0low20
Hepatocellular Cancer0low10
Hepatoma, Experimental0low20
Hepatoma, Morris0low20
Hepatoma, Novikoff0low20
Hepatomas, Experimental0low20
HIV Coinfection0medium11
HIV Infections0medium11
HTLV-III Infections0medium11
HTLV-III-LAV Infections0medium11
Human Mammary Carcinoma0medium21
Hydrops0low10
Infantile Canavan Disease0low10
Infections, Helicobacter0low10
Infections, Pneumococcal0low10
Infections, Streptococcus pneumoniae0low10
Injuries, Spinal Cord0low10
Intracranial Edema0low10
Intracranial Neoplasms0low20
Juvenile Canavan Disease0low10
Kahler Disease0low10
Keskushermoston sairaudet@fi0low10
Leukodystrophy, Spongiform0low10
Liver Cancer0low10
Liver Neoplasms0low10
Liver Neoplasms, Experimental0low20
Local Neoplasm Recurrence0medium11
Local Neoplasm Recurrences0medium11
Locoregional Neoplasm Recurrence0medium11
Lung Cancer0low20
Lung Neoplasms0low20
Maladie du systu00E8me nerveux central@fr0low10
Malattie del sistema nervoso centrale@it0low10
Malignancy0low10
Malignant Glioma0low30
Malignant Melanoma0low30
Malignant Neoplasm of Breast0medium21
Malignant Neoplasms0low10
Malignant Neoplasms, Brain0low20
Malignant Primary Brain Neoplasms0low20
Malignant Primary Brain Tumors0low20
Malignant Tumor of Breast0medium21
Mammary Cancer0medium21
Mammary Carcinoma, Human0medium21
Mammary Neoplasm, Human0medium21
Mammary Neoplasms, Human0medium21
Melanoma0low30
Melanoma, B160low10
Melanoma, Cloudman S910low10
Melanoma, Experimental0low10
Melanoma, Harding-Passey0low10
Melanomas, Experimental0low10
Mixed Glioma0low30
Mucoviscidosis0medium31
Multiple Myeloma0low10
Myeloma-Multiple0low10
Myeloma, Multiple0low10
Myeloma, Plasma-Cell0low10
Myelomatosis0low10
Myelopathy, Traumatic0low10
Neck Cancer0medium21
Neck Neoplasm0medium21
Neck Neoplasms0medium21
nemoci centru00E1lnu00EDho nervovu00E9ho systu00E9mu@cs0low10
Neonatal Canavan Disease0low10
Neoplasia0low10
Neoplasm0low10
Neoplasm Recurrence, Local0medium11
Neoplasm Recurrence, Locoregional0medium11
Neoplasm Recurrences, Local0medium11
Neoplasms0low10
Neoplasms, Benign0low10
Neoplasms, Brain0low20
Neoplasms, Brain, Benign0low20
Neoplasms, Brain, Malignant0low20
Neoplasms, Brain, Primary0low20
Neoplasms, Breast0medium21
Neoplasms, Experimental0low10
Neoplasms, Experimental Liver0low20
Neoplasms, Head0medium21
Neoplasms, Head and Neck0medium21
Neoplasms, Hepatic0low10
Neoplasms, Intracranial0low20
Neoplasms, Liver0low10
Neoplasms, Lung0low20
Neoplasms, Neck0medium21
Neoplasms, Ovarian0medium31
Neoplasms, Prostate0low10
Neoplasms, Prostatic0low10
Neoplasms, Pulmonary0low20
Neoplasms, Upper Aerodigestive Tract0medium21
Neovascularization, Pathologic0low10
Neovascularization, Pathological0low10
Neuroblastoma0low10
Ovarian Cancer0medium31
Ovarian Neoplasms0medium31
Ovary Cancer0medium31
Ovary Neoplasms0medium31
Pancreatic Cystic Fibrosis0medium31
Pathologic Angiogenesis0low10
Pathologic Neovascularization0low10
Peritoneal Carcinomatosis0low10
Peritoneal Neoplasms0low10
Peritoneal Surface Malignancy0low10
Plasma Cell Myeloma0low10
Pneumococcal Diseases0low10
Pneumococcal Infections0low10
Post-Traumatic Myelopathy0low10
Primary Brain Neoplasms0low20
Primary Malignant Brain Neoplasms0low20
Primary Malignant Brain Tumors0low20
Prostate Cancer0low10
Prostate Neoplasms0low10
Prostatic Cancer0low10
Prostatic Neoplasms0low10
Pulmonary Cancer0low20
Pulmonary Cystic Fibrosis0medium31
Pulmonary Neoplasms0low20
Recurrence, Local Neoplasm0medium11
Recurrence, Locoregional Neoplasm0medium11
Recurrences, Local Neoplasm0medium11
Spinal Cord Contusion0low10
Spinal Cord Injuries0low10
Spinal Cord Laceration0low10
Spinal Cord Transection0low10
Spinal Cord Trauma0low10
Spongy Degeneration Of Central Nervous System0low10
Spongy Degeneration of Infancy0low10
Spongy Degeneration of the Brain0low10
Spongy Degeneration of the Central Nervous System0low10
Spongy Degeneration of White Matter In Infancy0low10
Spongy Disease of Central Nervous System0low10
Spongy Disease of White Matter0low10
Sporadic Form of Canavan Disease0low10
Squamous Cell Carcinoma0medium11
SREDIu0160NJI u017DIVu010CANI SUSTAV, BOLESTI@hr0low10
Streptococcus pneumoniae Infections0low10
Sykdommer i sentralnervesystemet@no0low10
T-Lymphotropic Virus Type III Infections, Human0medium11
Tumors0low10
Tumors, Breast0medium21
Type I Canavan Disease0low10
Type II Canavan Disease0low10
Type III Canavan Disease0low10
u041Du0415u0420u0412u041Du041Eu0419 u0421u0418u0421u0422u0415u041Cu042B u0426u0415u041Du0422u0420u0410u041Bu042Cu041Du041Eu0419 u0411u041Eu041Bu0415u0417u041Du0418@ru0low10
u4E2Du67A2u795Eu7D4Cu7CFBu75BEu60A3@ja0low10
UADT Neoplasm0medium21
UADT Neoplasms0medium21
Upper Aerodigestive Tract Neoplasm0medium21
Upper Aerodigestive Tract Neoplasms0medium21
Van Bogaert-Bertrand Syndrome0low10
Vasogenic Brain Edema0low10
Vasogenic Cerebral Edema0low10
Von Bogaert-Bertrand Disease0low10
Zentralnervensystemkrankheiten@de0low10
Ziekte, centraalzenuwstelsel-@nl0low10
Zika Fever0low10
Zika Virus Disease0low10
Zika Virus Infection0low10
ZikV Infection0low10

Research Highlights

Safety/Toxicity (5)

ArticleYear
Safe and effective delivery of small interfering RNA with polymer- and liposomes-based complexes.
Biological & pharmaceutical bulletin, Volume: 36, Issue: 6		2013
The analysis of serum effects on structure, size and toxicity of DDAB-DOPE and DC-Chol-DOPE lipoplexes contributes to explain their different transfection efficiency.
Colloids and surfaces. B, Biointerfaces, Dec-01, Volume: 53, Issue: 2		2006
KLN-5: a safe monocationic lipophosphoramide to transfect efficiently haematopoietic cell lines and human CD34+ cells.
Biochimica et biophysica acta, Oct-11, Volume: 1665, Issue: 1-2		2004
Transfection efficiency and cytotoxicity of nonviral gene transfer reagents in human smooth muscle and endothelial cells.
Pharmaceutical research, Volume: 21, Issue: 6		2004
A novel tetraester construct that reduces cationic lipid-associated cytotoxicity. Implications for the onset of cytotoxicity.
Biochemistry, May-05, Volume: 37, Issue: 18		1998
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioavailability (2)

ArticleYear
A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
Molecular pharmacology, Volume: 96, Issue: 5		2019
Increase of the pharmacological and pharmacokinetic efficacy of negatively charged polypeptide recombinant hirudin in rats via parenteral route by association with cationic liposomes.
Journal of controlled release : official journal of the Controlled Release Society, Jun-04, Volume: 128, Issue: 2		2008
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Dosage (3)

ArticleYear
Pulmonary delivery of adenovirus vector formulated with dexamethasone-spermine facilitates homologous vector re-administration.
Gene therapy, Volume: 14, Issue: 22		2007
Liposome-mediated DNA immunisation via the subcutaneous route.
Journal of drug targeting, Volume: 11, Issue: 8-10		2003
Direct gene transfer to mouse melanoma by intratumor injection of free DNA.
Gene therapy, Volume: 3, Issue: 6		1996
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Interactions (1)

ArticleYear
Intranasal Immunization with DOTAP Cationic Liposomes Combined with DC-Cholesterol Induces Potent Antigen-Specific Mucosal and Systemic Immune Responses in Mice.
PloS one, Volume: 10, Issue: 10		2015
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]