pyrroles has been researched along with Neuroblastoma in 47 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (2.13) | 18.7374 |
| 1990's | 6 (12.77) | 18.2507 |
| 2000's | 13 (27.66) | 29.6817 |
| 2010's | 22 (46.81) | 24.3611 |
| 2020's | 5 (10.64) | 2.80 |
| Authors | Studies |
|---|---|
| Inoue, T; Nagase, H; Ota, Y; Shinozaki, Y; Takatori, A; Watanabe, T; Yoda, H | 1 |
| Ascanelli, C; Boi, D; Capelli, D; Carpinelli, P; Contestabile, R; Costi, R; De Leo, A; Di Santo, R; Guarguaglini, G; Lindon, C; Marini, G; Montanari, R; Paiardini, A; Pochetti, G; Polverino, F; Saviano, M; Souvalidou, F; Tramonti, A; Trisciuoglio, D | 1 |
| Buzdin, AA; Ivanenko, KA; Khabusheva, ER; Kudryavtseva, AV; Lebedev, TD; Mareeva, SR; Morozov, AV; Prassolov, VS; Rubtsov, PM; Snezhkina, AV; Sorokin, MI; Spirin, PV | 1 |
| Alexander, G; Bai, D; Chhonker, YS; Coulter, DW; Li, J; Li, R; Liu, Y; McGuire, TR; McIntyre, EM; Murry, DJ; Qiao, Z; Sharp, JG; Sughroue, JA; Yang, Z | 1 |
| Addioui, A; Beaunoyer, M; Belounis, A; Cournoyer, S; Haddad, E; Le Gall, R; Nyalendo, C; Sartelet, H; Teira, P; Vassal, G | 1 |
| Adderley, T; Christopher, G; Irwin, MS; Kano, Y; Kee, L; Ladumor, Y; Ohh, M; Robinson, CM; Valencia-Sama, I | 1 |
| Chupakhin, ON; Guzhova, IV; Lazarev, VF; Margulis, BA; Mikeladze, MA; Mikhaylova, ER; Trestsova, MA; Utepova, IA | 1 |
| Chen, X; Ding, X; Du, W; Fang, F; Hu, S; Li, M; Li, X; Li, Z; Lu, J; Pan, J; Qian, G; Ren, J; Tao, Y; Wang, J; Wu, Y; Xu, L; Xu, Y; Yang, C; Zhao, H | 1 |
| Granato, AEC; Lobo, AO; Marciano, FR; Porcionatto, M; Ribeiro, AC; Rodrigues, BVM | 1 |
| Inoue, T; Koshikawa, N; Lin, J; Nagase, H; Shinozaki, Y; Takatori, A; Watanabe, T; Yoda, H | 1 |
| Chang, XF; Ding, X; Han, W; Qin, H; Wang, HM; Wang, J; Wang, X; Yang, W; Zhang, JZ; Zhu, ZY | 1 |
| Bright, SA; Butini, S; Campiani, G; Carroll, E; Lennon, JC; O'Meara, A; Williams, DC; Zisterer, DM | 1 |
| Calero, R; Johnsen, JI; Morchon, E; Serrano, R | 1 |
| Acaz-Fonseca, E; Garcia-Segura, LM; Ghorbanpoor, S; Grassi, D; Ruiz-Palmero, I | 1 |
| Bantreil, X; Bojarski, AJ; Chaumont-Dubel, S; Colacino, E; Grychowska, K; Kos, T; Lamaty, F; Marin, P; Martinez, J; Partyka, A; Pawłowski, M; Popik, P; Satała, G; Subra, G; Wesołowska, A; Zajdel, P | 1 |
| Butini, S; Campiani, G; Lennon, JC; O'Meara, A; Williams, DC; Zisterer, DM | 1 |
| Fu, P; Huang, YZ; Li, HL; Shen, JY; Xiong, NX; Zhao, HY; Zuo, YC | 1 |
| Abbasnejad, M; Esmaeili-Mahani, S; Pasban-Aliabadi, H | 1 |
| Akaike, A; Izumi, Y; Kaneko, S; Katsuki, H; Kawato, Y; Kume, T; Nakagawa, T; Niidome, T; Osakada, F; Takada-Takatori, Y | 1 |
| Farace, F; Geoerger, B; Lagodny, J; Rössler, J; Taylor, M; Vassal, G | 1 |
| Baruchel, S; Chong, AL; Irwin, MS; Kaplan, DR; Marrano, P; Smith, KM; Stempak, D; Thorner, PS; Yeger, H; Zhang, L | 1 |
| Cascone, T; Heymach, JV; Nilsson, MB; Saigal, B; Wu, HK; Xu, L; Zage, PE; Zeng, L; Zweidler-McKay, PA | 1 |
| Kelleher, FC; McDermott, R | 1 |
| Andersen, E; Gopalakrishnan, M; Grønlien, JH; Lee, CH; Malysz, J; Thorin-Hagene, K; Ween, H | 1 |
| Banik, NL; Karmakar, S; Mohan, N; Ray, SK | 1 |
| Tuğlu, MI; Vural, K | 1 |
| Barnés, CM; Butterfield, C; Cassiola, F; Chaponis, D; Christison-Lagay, EA; Fallon, EM; Folkman, J; Kieran, M; Le, HD; Nehra, D; Panigrahy, D; Prox, D; Puder, M; Short, S | 1 |
| Arcaro, A; Bodmer, N; Cwiek, P; Djonov, V; Ghosal, A; Gross, N; Höland, K; Largey, F; Lucia Buccarello, A; Salm, F; Schäfer, SC; Styp-Rekowska, B; Westermann, F; Wotzkow, C; Zlobec, I | 1 |
| Futagami, K; Kataoka, Y; Nakashima, A; Nishioku, T; Watanabe, T; Yamauchi, A; Yasutaka, Y | 1 |
| Davidoff, AM; Hartwich, J; Morton, C; Ng, CY; Orr, WS; Spence, Y | 1 |
| Larsson, C; Svensson, K | 1 |
| Gong, H; Havers, W; Pöttgen, C; Schweigerer, L; Stüben, G; Stuschke, M | 1 |
| Bäckman, U; Christofferson, R; Svensson, A | 1 |
| Bogush, A; Buxbaum, JD; Diaz, N; Ehrlich, M; Gandy, S; Parvathy, S; Pedrini, S; Petanceska, S; Refolo, L | 1 |
| Carter, TL; Ehrlich, ME; Gandy, S; Pedrini, S; Petanceska, S; Prendergast, G | 1 |
| Barnes, NY; Parent, AT; Sisodia, SS; Taniguchi, Y; Thinakaran, G | 1 |
| Dominici, C; Mancini, C; Mancuso, M; McDowell, HP; Raschellà, G; Tanno, B; Vitali, R | 1 |
| Chesler, L; Gable, K; Goldenberg, DD; Goldfine, ID; Liu, D; Maddux, BA; Matthay, KK; Meyer, GE; Rosenthal, SM; Weiss, WA; Youngren, JF | 1 |
| Lee, YS; Sayeed, MM; Wurster, RD | 1 |
| Herman, MD; Narahashi, T; Reuveny, E | 1 |
| Matsumura, K; Mochizuki-Oda, N; Oosawa, Y; Takeuchi, Y; Watanabe, Y | 1 |
| Chakrabarti, S; Law, PY; Loh, HH | 1 |
| Chari, S; Deth, RC; DuRand, CJ; Kotb, M; Kramer, ML; Liu, D; Nagata, M; Ouellette, D; Sharma, A; Shim, S; Tan, W; Wick, PF | 1 |
| Larsson, C; Svensson, K; Trollér, U; Zeidman, R | 1 |
| Bäckman, U; Christofferson, R; Jonsson, E; Larsson, R; Svensson, A | 1 |
| Ishii, DN; Maniatis, GM | 1 |
| Higashida, H; Ito, Y; Matsubara, T; Miyamori, I; Takeda, R | 1 |
2 review(s) available for pyrroles and Neuroblastoma
| Article | Year |
|---|---|
[Potential role of antiangiogenic treatment in neuroblastoma].
Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bevacizumab; Child; Clinical Trials as Topic; Humans; Indoles; Neovascularization, Pathologic; Neuroblastoma; Pyrroles; Sunitinib; United States; United States Food and Drug Administration | 2009 |
The emerging pathogenic and therapeutic importance of the anaplastic lymphoma kinase gene.
Topics: Anaplastic Lymphoma Kinase; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Chromosome Aberrations; Chromosomes, Human, Pair 2; Drug Synergism; Gene Amplification; Humans; Lung Neoplasms; Lymphoma, Large-Cell, Anaplastic; Mutation; Neoplasms; Neuroblastoma; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles; Receptor Protein-Tyrosine Kinases; Receptor, IGF Type 1 | 2010 |
45 other study(ies) available for pyrroles and Neuroblastoma
| Article | Year |
|---|---|
Targeting anaplastic lymphoma kinase (ALK) gene alterations in neuroblastoma by using alkylating pyrrole-imidazole polyamides.
Topics: Anaplastic Lymphoma Kinase; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Down-Regulation; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; Mice; Mutation; Neuroblastoma; Nylons; Phosphorylation; Pyrroles; Xenograft Model Antitumor Assays | 2021 |
PHA-680626 Is an Effective Inhibitor of the Interaction between Aurora-A and N-Myc.
Topics: Adenosine Triphosphate; Antineoplastic Agents; Aurora Kinase A; Azepines; Benzazepines; Binding Sites; Binding, Competitive; Cell Line; Drug Evaluation, Preclinical; Humans; N-Myc Proto-Oncogene Protein; Neuroblastoma; Protein Conformation; Protein Kinase Inhibitors; Pyrazoles; Pyrimidines; Pyrroles; Surface Plasmon Resonance | 2021 |
Identification of cell type-specific correlations between ERK activity and cell viability upon treatment with ERK1/2 inhibitors.
Topics: Aminopyridines; Antineoplastic Agents; Benzamides; Cell Line, Tumor; Cell Survival; Diphenylamine; Humans; Indazoles; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinases; Neuroblastoma; Piperazines; Protein Kinase Inhibitors; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins p21(ras); Pyrazoles; Pyridones; Pyrimidines; Pyrroles | 2022 |
Effects of novel pyrrolomycin MP1 in MYCN amplified chemoresistant neuroblastoma cell lines alone and combined with temsirolimus.
Topics: Animals; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Biomarkers; Cell Cycle; Cell Line, Tumor; Disease Models, Animal; Drug Interactions; Drug Resistance, Neoplasm; Gene Amplification; Humans; Mice; Molecular Structure; N-Myc Proto-Oncogene Protein; Neuroblastoma; Pyrroles; Sirolimus; Spectrum Analysis; Xenograft Model Antitumor Assays | 2019 |
GX15-070 (Obatoclax), a Bcl-2 family proteins inhibitor engenders apoptosis and pro-survival autophagy and increases Chemosensitivity in neuroblastoma.
Topics: Adrenal Gland Neoplasms; Animals; Antineoplastic Agents; Apoptosis; Autophagy; Cell Line, Tumor; Cell Survival; Drug Resistance, Neoplasm; Drug Synergism; Female; Humans; Hydroxychloroquine; Indoles; Male; Mice; Mice, Inbred NOD; Mice, SCID; Neuroblastoma; Proto-Oncogene Proteins c-bcl-2; Pyrroles; Tumor Burden; Xenograft Model Antitumor Assays | 2019 |
Topics: Aminopyridines; Animals; Antineoplastic Agents; Cell Line, Tumor; Drug Resistance, Neoplasm; Drug Synergism; Genes, ras; Heterografts; Humans; Indoles; Male; MAP Kinase Signaling System; Mice, Inbred NOD; Mice, SCID; Mitogen-Activated Protein Kinase Kinases; Mutation; Neoplasm Recurrence, Local; Neuroblastoma; Piperidines; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Pyridones; Pyrimidines; Pyrimidinones; Pyrroles; Triazoles; Vemurafenib | 2020 |
Indolyl- and Pyrrolylazine Derivatives Cause the Accumulation of Heat Shock Protein Hsp70 in Sh-Sy5Y Human Neuroblastoma Cells.
Topics: Cell Line, Tumor; HSP70 Heat-Shock Proteins; Humans; Indoles; Neuroblastoma; Neurons; Pyrroles | 2020 |
Inhibition of neuroblastoma proliferation by PF-3758309, a small-molecule inhibitor that targets p21-activated kinase 4.
Topics: Adult; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Female; Gene Expression Regulation, Neoplastic; Humans; Male; MAP Kinase Signaling System; Neoplasm Staging; Neuroblastoma; p21-Activated Kinases; Protein Kinase Inhibitors; Pyrazoles; Pyrroles; Up-Regulation | 2017 |
Polypyrrole increases branching and neurite extension by Neuro2A cells on PBAT ultrathin fibers.
Topics: Animals; Cell Adhesion; Cell Differentiation; Cell Proliferation; Mesenchymal Stem Cells; Mice; Mice, Inbred C57BL; Nanofibers; Neurites; Neuroblastoma; Polyesters; Polymers; Pyrroles; Tissue Scaffolds; Tumor Cells, Cultured | 2018 |
Direct Targeting of
Topics: Alkylation; Animals; Antineoplastic Agents, Alkylating; Apoptosis; Biomarkers, Tumor; Cell Proliferation; Female; Gene Amplification; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; Mice; Mice, Inbred BALB C; Mice, Nude; N-Myc Proto-Oncogene Protein; Neuroblastoma; Nylons; Pyrroles; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2019 |
IGF-1 alleviates serum IgG-induced neuronal cytolysis through PI3K signaling in children with opsoclonus-myoclonus syndrome and neuroblastoma.
Topics: Animals; Cells, Cultured; Child, Preschool; Chromones; Female; Humans; Immunoglobulin G; Insulin-Like Growth Factor I; Male; Morpholines; Neuroblastoma; Neurons; Opsoclonus-Myoclonus Syndrome; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Pyrimidines; Pyrroles; Rats; Receptor, IGF Type 1; Signal Transduction | 2019 |
The novel pyrrolo-1,5-benzoxazepine, PBOX-6, synergistically enhances the apoptotic effects of carboplatin in drug sensitive and multidrug resistant neuroblastoma cells.
Topics: Antineoplastic Agents; Apoptosis; Carboplatin; Cell Line, Tumor; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Humans; Neuroblastoma; Oxazepines; Pyrroles; Up-Regulation | 2014 |
Sunitinib suppress neuroblastoma growth through degradation of MYCN and inhibition of angiogenesis.
Topics: Animals; Apoptosis; Cell Cycle; Cell Line; Cell Line, Tumor; Cell Proliferation; Cell Survival; Female; Humans; Indoles; Mice; Mice, Nude; N-Myc Proto-Oncogene Protein; Neovascularization, Pathologic; Neuroblastoma; Nuclear Proteins; Oncogene Proteins; Proto-Oncogene Mas; Pyrroles; Reverse Transcriptase Polymerase Chain Reaction; Sunitinib | 2014 |
The Selective Estrogen Receptor Modulator Raloxifene Regulates Arginine-Vasopressin Gene Expression in Human Female Neuroblastoma Cells Through G Protein-Coupled Estrogen Receptor and ERK Signaling.
Topics: Arginine Vasopressin; Blotting, Western; Cell Line, Tumor; Extracellular Signal-Regulated MAP Kinases; Female; Gene Expression Regulation, Neoplastic; Humans; MAP Kinase Signaling System; Neuroblastoma; Phosphorylation; Protein Kinase C; Pyrroles; Quinazolines; Raloxifene Hydrochloride; Receptors, Estrogen; Receptors, G-Protein-Coupled; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA, Messenger; Selective Estrogen Receptor Modulators | 2015 |
Novel 1H-Pyrrolo[3,2-c]quinoline Based 5-HT6 Receptor Antagonists with Potential Application for the Treatment of Cognitive Disorders Associated with Alzheimer's Disease.
Topics: Alzheimer Disease; Animals; CHO Cells; Cognition Disorders; Cricetulus; Cyclic AMP; Disease Models, Animal; HEK293 Cells; Humans; Male; Neuroblastoma; Phencyclidine; Pyrroles; Quinolines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Serotonin; Serotonin Antagonists; Sulfones | 2016 |
Involvement of AMP-activated protein kinase in mediating pyrrolo-1,5-benzoxazepine-induced apoptosis in neuroblastoma cells.
Topics: Acetyl-CoA Carboxylase; Acetylcysteine; AMP-Activated Protein Kinases; Animals; Antineoplastic Agents; Antioxidants; Apoptosis; Carboplatin; Cell Line, Tumor; Female; Humans; Mechanistic Target of Rapamycin Complex 1; Mice, Inbred BALB C; Mice, Nude; Myeloid Cell Leukemia Sequence 1 Protein; Neuroblastoma; Oxazepines; Phosphorylation; Pyrroles; Reactive Oxygen Species; Tubulin Modulators; Tumor Burden | 2016 |
Overexpression of Tau Rescues Nogo-66-Induced Neurite Outgrowth Inhibition In Vitro.
Topics: Analysis of Variance; Animals; Azepines; Cells, Cultured; Cerebral Cortex; Embryo, Mammalian; Enzyme Inhibitors; Female; Gene Expression Regulation; Green Fluorescent Proteins; Humans; Mice; Neurites; Neuroblastoma; Neurons; Nogo Proteins; Protein Serine-Threonine Kinases; Pyrroles; Rats; Rats, Sprague-Dawley; tau Proteins; Time Factors; Transfection | 2016 |
Orexin-A Protects Human Neuroblastoma SH-SY5Y Cells Against 6-Hydroxydopamine-Induced Neurotoxicity: Involvement of PKC and PI3K Signaling Pathways.
Topics: Benzophenanthridines; Calcium; Carbazoles; Cell Line, Tumor; Cell Survival; Chromones; Cyclooxygenase 2; HSP70 Heat-Shock Proteins; Humans; Intracellular Space; Membrane Potential, Mitochondrial; Morpholines; Neuroblastoma; Neuroprotective Agents; Neurotoxins; NF-E2-Related Factor 2; Orexin Receptors; Orexins; Oxidopamine; Phosphatidylinositol 3-Kinases; Protein Kinase C; Protein Kinase Inhibitors; Pyrroles; Signal Transduction | 2017 |
Dibutyryl cyclic AMP induces differentiation of human neuroblastoma SH-SY5Y cells into a noradrenergic phenotype.
Topics: alpha-Methyltyrosine; Animals; Antineoplastic Agents; Butyrates; Carbazoles; Cell Differentiation; Cell Line, Tumor; Cyclic CMP; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Neuroblastoma; Norepinephrine; Phenotype; Pyrroles; Tretinoin; Tyrosine 3-Monooxygenase | 2008 |
In vivo antitumor and antimetastatic activity of sunitinib in preclinical neuroblastoma mouse model.
Topics: Angiogenesis Inhibitors; Animals; Blotting, Western; Cell Line, Tumor; Disease Models, Animal; Gene Expression; Humans; Immunohistochemistry; Indoles; Mice; Neovascularization, Pathologic; Neuroblastoma; Oligonucleotide Array Sequence Analysis; Pyrroles; Sunitinib; Xenograft Model Antitumor Assays | 2009 |
Multiple receptor tyrosine kinases regulate HIF-1alpha and HIF-2alpha in normoxia and hypoxia in neuroblastoma: implications for antiangiogenic mechanisms of multikinase inhibitors.
Topics: Angiogenesis Inhibitors; Animals; Basic Helix-Loop-Helix Transcription Factors; Blotting, Western; Cell Movement; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Immunoenzyme Techniques; Indoles; Mice; Mice, Inbred NOD; Mice, SCID; Neovascularization, Pathologic; Neuroblastoma; Proto-Oncogene Proteins c-kit; Proto-Oncogene Proteins c-ret; Pyrroles; Receptor Protein-Tyrosine Kinases; Receptor, Platelet-Derived Growth Factor beta; Receptors, Interleukin-2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Sunitinib; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-3; Xenograft Model Antitumor Assays | 2010 |
Alpha3* and alpha 7 nAChR-mediated Ca2+ transient generation in IMR-32 neuroblastoma cells.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Benzamides; Brain Neoplasms; Bridged Bicyclo Compounds; Calcium Channel Blockers; Calcium Signaling; Calcium-Transporting ATPases; Cell Line, Tumor; Data Interpretation, Statistical; Diltiazem; Electrophysiology; Endoplasmic Reticulum; Humans; Neuroblastoma; Nicotinic Agonists; Nitrendipine; Patch-Clamp Techniques; Pyrroles; Receptors, Nicotinic; Sulfonamides | 2010 |
SU5416 and EGCG work synergistically and inhibit angiogenic and survival factors and induce cell cycle arrest to promote apoptosis in human malignant neuroblastoma SH-SY5Y and SK-N-BE2 cells.
Topics: Angiogenesis Inhibitors; Anticarcinogenic Agents; Apoptosis; Catechin; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Survival; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p21; E2F1 Transcription Factor; Humans; In Situ Nick-End Labeling; Indoles; Neovascularization, Pathologic; Neuroblastoma; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; Pyrroles; Retinoblastoma Protein; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2 | 2011 |
Neurotoxic effect of statins on mouse neuroblastoma NB2a cell line.
Topics: Animals; Atorvastatin; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Mice; Neurites; Neuroblastoma; Pyrroles | 2011 |
Inhibition of neuroblastoma cell proliferation with omega-3 fatty acids and treatment of a murine model of human neuroblastoma using a diet enriched with omega-3 fatty acids in combination with sunitinib.
Topics: Angiogenesis Inhibitors; Animals; Arachidonic Acid; Cell Line, Tumor; Cell Proliferation; Diet; Dose-Response Relationship, Drug; Fatty Acids, Omega-3; Fish Oils; Humans; Indoles; Lipid Metabolism; Male; Mice; Mice, SCID; Microvessels; Mitochondria; Neuroblastoma; Protein Kinase Inhibitors; Pyrroles; Sunitinib; Time Factors; Tumor Burden; Xenograft Model Antitumor Assays | 2012 |
RNA interference screening identifies a novel role for autocrine fibroblast growth factor signaling in neuroblastoma chemoresistance.
Topics: Antineoplastic Agents; Apoptosis; bcl-X Protein; Biphenyl Compounds; Blotting, Western; Cell Line, Tumor; Cell Survival; Cisplatin; Drug Resistance, Neoplasm; Enzyme Activation; Fibroblast Growth Factor 2; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Neuroblastoma; Nitrophenols; Oligonucleotide Array Sequence Analysis; Piperazines; Protein Kinase C-delta; Proto-Oncogene Proteins c-bcl-2; Pyrroles; Receptor, Fibroblast Growth Factor, Type 2; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Signal Transduction; Sulfonamides | 2013 |
Atorvastatin stimulates neuroblastoma cells to induce neurite outgrowth by increasing cellular prion protein expression.
Topics: Animals; Atorvastatin; Cell Line, Tumor; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mice; Neurites; Neuroblastoma; Prions; Pyrroles; Reverse Transcriptase Polymerase Chain Reaction | 2012 |
HIF-1α activation mediates resistance to anti-angiogenic therapy in neuroblastoma xenografts.
Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Biomarkers, Tumor; Cell Line, Tumor; Drug Administration Schedule; Drug Resistance, Neoplasm; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Indoles; Injections, Intraperitoneal; Mice; Mice, SCID; Neuroblastoma; Pyrroles; Reverse Transcriptase Polymerase Chain Reaction; Sunitinib; Topoisomerase I Inhibitors; Topotecan; Treatment Outcome; Tumor Burden | 2013 |
A protein kinase Cbeta inhibitor attenuates multidrug resistance of neuroblastoma cells.
Topics: Carboplatin; Cell Line, Tumor; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Humans; Indoles; Maleimides; Mesylates; Neuroblastoma; Paclitaxel; Peripheral Nervous System Neoplasms; Protein Kinase C; Pyrroles; Tumor Cells, Cultured; Vincristine | 2003 |
Arginine deiminase and other antiangiogenic agents inhibit unfavorable neuroblastoma growth: potentiation by irradiation.
Topics: Angiogenesis Inhibitors; Animals; Cell Division; Cell Hypoxia; Combined Modality Therapy; Endothelium, Vascular; Gene Expression Regulation, Neoplastic; Humans; Hydrolases; Indoles; Mice; Mice, Nude; Neuroblastoma; Protein-Tyrosine Kinases; Pyrroles; Tumor Cells, Cultured; Whole-Body Irradiation; Xenograft Model Antitumor Assays | 2003 |
Importance of vascular endothelial growth factor A in the progression of experimental neuroblastoma.
Topics: Angiogenesis Inhibitors; Animals; Cell Division; Endothelial Growth Factors; Female; Humans; Indoles; Male; Mice; Mice, Nude; Neoplasms, Experimental; Neuroblastoma; Protein-Tyrosine Kinases; Pyrroles; Transplantation, Heterologous; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A | 2002 |
Atorvastatin-induced activation of Alzheimer's alpha secretase is resistant to standard inhibitors of protein phosphorylation-regulated ectodomain shedding.
Topics: Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Atorvastatin; Cell Line, Tumor; Dose-Response Relationship, Drug; Endopeptidases; Enzyme Activation; Enzyme Activators; Enzyme Inhibitors; Genes, Dominant; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mice; Mitogen-Activated Protein Kinases; Mutation; Neuroblastoma; Phosphorylation; Protein Kinase C; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Protein Structure, Tertiary; Pyrroles | 2004 |
Modulation of statin-activated shedding of Alzheimer APP ectodomain by ROCK.
Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Protein Precursor; Atorvastatin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intracellular Signaling Peptides and Proteins; Molecular Sequence Data; Neuroblastoma; Phosphorylation; Protein Serine-Threonine Kinases; Pyrroles; rho-Associated Kinases; Simvastatin; Tumor Cells, Cultured | 2005 |
Presenilin attenuates receptor-mediated signaling and synaptic function.
Topics: Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Carbamates; Carbazoles; Cell Adhesion Molecules; Cell Line, Tumor; Cell Membrane; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; DCC Receptor; Dipeptides; Endopeptidases; Excitatory Postsynaptic Potentials; Genes, DCC; Glutamic Acid; Indoles; Lidocaine; Membrane Proteins; Memory; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurites; Neuroblastoma; Neurons; Piperazines; Presenilin-1; Protein Processing, Post-Translational; Pyrroles; Quinoxalines; Rats; Receptors, Cell Surface; Recombinant Fusion Proteins; Second Messenger Systems; Synaptic Transmission; Transfection; Tumor Suppressor Proteins | 2005 |
Down-regulation of insulin-like growth factor I receptor activity by NVP-AEW541 has an antitumor effect on neuroblastoma cells in vitro and in vivo.
Topics: Adrenal Gland Neoplasms; Animals; Antineoplastic Agents; Brain Neoplasms; Cell Proliferation; Down-Regulation; Humans; Kidney Neoplasms; Male; Mice; Mice, Nude; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neoplasm Invasiveness; Neuroblastoma; Phosphorylation; Proto-Oncogene Proteins c-akt; Pyrimidines; Pyrroles; Receptor, IGF Type 1; Transplantation, Heterologous; Tumor Burden; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2006 |
Nordihydroguaiaretic acid inhibits insulin-like growth factor signaling, growth, and survival in human neuroblastoma cells.
Topics: Animals; Apoptosis; Caspase 3; Cell Culture Techniques; Cell Movement; Cell Proliferation; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Humans; Insulin-Like Growth Factor I; Masoprocol; Mice; Mice, Nude; Neuroblastoma; Phosphorylation; Propidium; Proto-Oncogene Proteins c-akt; Pyrimidines; Pyrroles; Receptor, IGF Type 1; Signal Transduction; Xenograft Model Antitumor Assays | 2007 |
In vitro antitumor activity of cromakalim in human brain tumor cells.
Topics: Antineoplastic Agents; Astrocytoma; Benzopyrans; Brain; Brain Neoplasms; Calcium; Cell Survival; Cromakalim; Dose-Response Relationship, Drug; Humans; Neuroblastoma; Potassium Channels; Pyrroles; Sulfonylurea Compounds; Tumor Cells, Cultured | 1994 |
The effect of polyamines on voltage-activated calcium channels in mouse neuroblastoma cells.
Topics: Alkaloids; Animals; Calcium Channels; Carbazoles; Electric Stimulation; Indoles; Membrane Potentials; Mice; Neuroblastoma; Polyamines; Protein Kinase C; Putrescine; Pyrroles; Staurosporine; Tumor Cells, Cultured | 1993 |
Hypoxia-induced catecholamine release and intracellular Ca2+ increase via suppression of K+ channels in cultured rat adrenal chromaffin cells.
Topics: Animals; Benzopyrans; Buffers; Calcium; Carotid Body; Catecholamines; Cell Hypoxia; CHO Cells; Chromaffin Cells; Cricetinae; Cromakalim; Diazoxide; Glioma; Glyburide; Guanidines; Hybrid Cells; Hypoglycemic Agents; Male; Membrane Potentials; Minoxidil; Neuroblastoma; Parasympatholytics; Patch-Clamp Techniques; Pinacidil; Potassium; Potassium Channel Blockers; Potassium Channels; Pyrroles; Rats; Rats, Wistar; Vasodilator Agents | 1997 |
Distinct differences between morphine- and [D-Ala2,N-MePhe4,Gly-ol5]-enkephalin-mu-opioid receptor complexes demonstrated by cyclic AMP-dependent protein kinase phosphorylation.
Topics: Analgesics, Opioid; Antibody Specificity; Carbazoles; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Enzyme Inhibitors; Indoles; Morphine; Neuroblastoma; Neurons; Phosphorylation; Precipitin Tests; Pyrroles; Receptors, Opioid, mu; Tumor Cells, Cultured | 1998 |
D4 dopamine receptor-mediated phospholipid methylation and its implications for mental illnesses such as schizophrenia.
Topics: Amino Acid Sequence; Aminopyridines; Animals; Benzazepines; Binding Sites; Carbon Radioisotopes; CHO Cells; Clozapine; Cricetinae; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Formates; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Methionine; Mutagenesis, Site-Directed; Neuroblastoma; Phospholipids; Phosphorylation; Piperidines; Psychotic Disorders; Pyridines; Pyrroles; Raclopride; Receptors, Dopamine D2; Receptors, Dopamine D4; Recombinant Proteins; S-Adenosylmethionine; Salicylamides; Schizophrenia; Transfection; Tumor Cells, Cultured | 1999 |
A PKCbeta isoform mediates phorbol ester-induced activation of Erk1/2 and expression of neuronal differentiation genes in neuroblastoma cells.
Topics: Cell Differentiation; Culture Media, Serum-Free; Enzyme Inhibitors; Flavonoids; GAP-43 Protein; Gene Expression Regulation; Genes, Reporter; Isoenzymes; Mesylates; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neurites; Neuroblastoma; Neurons; Neuropeptide Y; Phosphorylation; Promoter Regions, Genetic; Protein Kinase C; Protein Kinase C beta; Pyrroles; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2001 |
CHS 828 inhibits neuroblastoma growth in mice alone and in combination with antiangiogenic drugs.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Division; Cyanides; Cyclohexanes; Guanidines; Humans; Indoles; Male; Mice; Mice, Nude; Neovascularization, Pathologic; Neuroblastoma; O-(Chloroacetylcarbamoyl)fumagillol; Pyrroles; Remission Induction; Sesquiterpenes; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2002 |
Haemin promotes rapid neurite outgrowth in cultured mouse neuroblastoma cells.
Topics: Cell Differentiation; Cell Division; Cell Line; Cell Survival; Heme; Hemin; Neuroblastoma; Neurons; Protein Kinases; Pyrroles; Structure-Activity Relationship | 1978 |
Cromakalim, a vasodilator, differentially inhibits Ca2+ currents in NG108-15 neuroblastoma x glioma hybrid cells.
Topics: Animals; Antihypertensive Agents; Benzopyrans; Biological Transport; Calcium; Cromakalim; Glioma; Hybrid Cells; Membrane Potentials; Mice; Neuroblastoma; Parasympatholytics; Pyrroles; Tumor Cells, Cultured; Vasodilator Agents | 1990 |