Page last updated: 2024-10-15

acetylcarnitine and Neuroblastoma

acetylcarnitine has been researched along with Neuroblastoma in 4 studies

Acetylcarnitine: An acetic acid ester of CARNITINE that facilitates movement of ACETYL COA into the matrices of mammalian MITOCHONDRIA during the oxidation of FATTY ACIDS.

Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)

Research Excerpts

ExcerptRelevanceReference
" The present study investigates the effects of ALCAR against the toxicity of 1-methyl-4-phenylpyridinium (MPP(+)), the neurotoxic metabolite of MPTP, in murine brain neuroblastoma cells."7.72Acetyl-L-carnitine cytoprotection against 1-methyl-4-phenylpyridinium toxicity in neuroblastoma cells. ( Mazzio, E; Soliman, KF; Yoon, KJ, 2003)
" The present study investigates the effects of ALCAR against the toxicity of 1-methyl-4-phenylpyridinium (MPP(+)), the neurotoxic metabolite of MPTP, in murine brain neuroblastoma cells."3.72Acetyl-L-carnitine cytoprotection against 1-methyl-4-phenylpyridinium toxicity in neuroblastoma cells. ( Mazzio, E; Soliman, KF; Yoon, KJ, 2003)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's1 (25.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Bae, JE1
Kim, JB1
Jo, DS1
Park, NY1
Kim, YH1
Lee, HJ1
Kim, SH2
Son, M1
Kim, P1
Ryu, HY1
Lee, WH1
Ryoo, ZY1
Lee, HS1
Jung, YK1
Cho, DH1
Altun, ZS1
Güneş, D1
Aktaş, S1
Erbayraktar, Z1
Erbayrktar, Z1
Olgun, N1
Mazzio, E1
Yoon, KJ1
Soliman, KF1
Dhitavat, S1
Ortiz, D1
Rogers, E1
Rivera, E1
Shea, TB1

Other Studies

4 other studies available for acetylcarnitine and Neuroblastoma

ArticleYear
Carnitine Protects against MPP
    Cells, 2022, 09-01, Volume: 11, Issue:17

    Topics: 1-Methyl-4-phenylpyridinium; Acetylcarnitine; Apoptosis; Carnitine; Cell Line, Tumor; Dopaminergic N

2022
Protective effects of acetyl-L-carnitine on cisplatin cytotoxicity and oxidative stress in neuroblastoma.
    Neurochemical research, 2010, Volume: 35, Issue:3

    Topics: Acetylcarnitine; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Prolifera

2010
Acetyl-L-carnitine cytoprotection against 1-methyl-4-phenylpyridinium toxicity in neuroblastoma cells.
    Biochemical pharmacology, 2003, Jul-15, Volume: 66, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Acetylcarnitine; Adenosin

2003
Folate, vitamin E, and acetyl-L-carnitine provide synergistic protection against oxidative stress resulting from exposure of human neuroblastoma cells to amyloid-beta.
    Brain research, 2005, Nov-09, Volume: 1061, Issue:2

    Topics: Acetylcarnitine; Adenosine Triphosphate; Amyloid beta-Peptides; Antioxidants; Brain Neoplasms; Cell

2005