Compounds > cauloside c
Page last updated: 2024-11-12

cauloside c

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Cross-References

ID SourceID
PubMed CID13878151
CHEMBL ID537960
CHEBI ID81174
MeSH IDM0069575

Synonyms (28)

Synonym
cauloside c
akeboside std
akebia saponin c
C17547
20853-58-1
chebi:81174 ,
CHEMBL537960
3-((2-0-beta-d-glucopyranosyl-alpha-l-arabinopyranosyl)oxy)-23-hydroxyolean-12-en-28-oic acid
hederoside d2
fatsiaside d1
909ogz2782 ,
alpha-fatsin
unii-909ogz2782
calthoside d
olean-12-en-28-oic acid, 3-((2-o-.beta.-d-glucopyranosyl-.alpha.-l-arabinopyranosyl)oxy)-23-hydroxy-, (3.beta.,4.alpha.)-
3-((2-0-.beta.-d-glucopyranosyl-.alpha.-l-arabinopyranosyl)oxy)-23-hydroxyolean-12-en-28-oic acid
.alpha.-fatsin
hederagenin 3-o-.beta.-d-glucopyranosyl(1->2)-o-.alpha.-l-arabinopyranosid
olean-12-en-28-oic acid, 3.beta.-((2-o-.beta.-d-glucopyranosyl-.alpha.-l-arabinopyranosyl)oxy)-23-hydroxy-
Q27155129
HY-N6919
CS-0092099
MS-31381
(4as,6ar,6as,6br,8ar,9r,10s,12ar,14bs)-10-[(2s,3r,4s,5s)-4,5-dihydroxy-3-[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-9-(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4
olean-12-en-28-oic acid, 3-((2-o-beta-d-glucopyranosyl-alpha-l-arabinopyranosyl)oxy)-23-hydroxy-, (3beta,4alpha)-
olean-12-en-28-oic acid, 3beta-((2-o-beta-d-glucopyranosyl-alpha-l-arabinopyranosyl)oxy)-23-hydroxy-
hederagenin 3-o-beta-d-glucopyranosyl(1->2)-o-alpha-l-arabinopyranosid
AKOS040741511
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
triterpenoidAny terpenoid derived from a triterpene. The term includes compounds in which the C30 skeleton of the parent triterpene has been rearranged or modified by the removal of one or more skeletal atoms (generally methyl groups).
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Bioassays (1)

Assay IDTitleYearJournalArticle
AID429971Cytotoxicity against human HL60 cells after 72 hrs by MTT assay2009Journal of natural products, Jun, Volume: 72, Issue:6
Triterpene glycosides from the underground parts of Caulophyllum thalictroides.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (16.67)18.7374
1990's2 (33.33)18.2507
2000's2 (33.33)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.41

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.41 (24.57)
Research Supply Index2.30 (2.92)
Research Growth Index4.71 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.41)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other9 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
oleanolic acid
[no description available]		3.0950hydroxy monocarboxylic acid;
pentacyclic triterpenoid		plant metabolite
etoposide
[no description available]		2.0510beta-D-glucoside;
furonaphthodioxole;
organic heterotetracyclic compound		antineoplastic agent;
DNA synthesis inhibitor
stichoposide
stichoposide: triterpene glycoside; RN given refers to stichoposide A		1.9610
cussonoside a
cussonoside A: triterpene saponin from Cussonia barteri (Araliaceae) with sedative effect;		2.0510
3-o-(alpha-l-arabinopyranosyl)hederagenin
Akebia saponin PA: isolated from Dipsacus asperoides; structure in first source. hederagenin 3-O-arabinoside : A triterpenoid saponin that is hederagenin attached to an alpha-L-arabinopyranosyl residue at position 3 via a glycosidic linkage.		2.110alpha-L-arabinopyranoside;
hydroxy monocarboxylic acid;
monosaccharide derivative;
pentacyclic triterpenoid;
triterpenoid saponin		plant metabolite
glycosides
[no description available]		2.6730
beta-escin
[no description available]		2.420
cauloside D
[no description available]		2.0510carboxylic ester;
pentacyclic triterpenoid;
triterpenoid saponin		anti-inflammatory agent;
plant metabolite
holothurin a
holothurin A: RN given refers to Na salt (3 beta,12 alpha,22S)-isomer		1.9610
holothurin
Holothurin: A highly toxic saponin occurring in HOLOTHUROIDEA. This marine toxin is an anionic surfactant, hemolyzing ERYTHROCYTES.		1.9610
ConditionIndicatedRelationship StrengthStudiesTrials
Extravascular Hemolysis
[description not available]		01.9910
Hemolysis
The destruction of ERYTHROCYTES by many different causal agents such as antibodies, bacteria, chemicals, temperature, and changes in tonicity.		01.9910
Carcinoma, Ehrlich Tumor
A transplantable, poorly differentiated malignant tumor which appeared originally as a spontaneous breast carcinoma in a mouse. It grows in both solid and ascitic forms.		0210
Neuroblastoma
A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)		0210