Page last updated: 2024-10-25

ciglitazone and Neuroblastoma

ciglitazone has been researched along with Neuroblastoma in 1 studies

ciglitazone: structure given in second source; PPAR agonist used for type II diabetes
ciglitazone : An aromatic ether that consists of 1,3-thiazolidine-2,4-dione with position 5 substituted by a 4-[(1-methylcyclohexyl)methoxy]benzyl group. A selective PPARgamma agonist.

Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)

Research Excerpts

ExcerptRelevanceReference
"Neuroblastoma is a childhood cancer, which spontaneously regresses."1.32Regulation of cellular processes by PPARgamma ligands in neuroblastoma cells is modulated by the level of retinoblastoma protein expression. ( Emmans, VC; Hunt, AN; Lillycrop, KA; Rodway, HA, 2004)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Emmans, VC1
Rodway, HA1
Hunt, AN1
Lillycrop, KA1

Other Studies

1 other study available for ciglitazone and Neuroblastoma

ArticleYear
Regulation of cellular processes by PPARgamma ligands in neuroblastoma cells is modulated by the level of retinoblastoma protein expression.
    Biochemical Society transactions, 2004, Volume: 32, Issue:Pt 5

    Topics: Carboxy-Lyases; Cell Line, Tumor; Dose-Response Relationship, Drug; Enzyme Inhibitors; Genes, Report

2004