Proteins > Nicotinamide phosphoribosyltransferase
Page last updated: 2024-08-07 18:21:16
Nicotinamide phosphoribosyltransferase
A nicotinamide phosphoribosyltransferase that is encoded in the genome of mouse. [OMA:Q99KQ4, PRO:DNx]
Synonyms
NAmPRTase;
Nampt;
EC 2.4.2.12;
Pre-B-cell colony-enhancing factor 1 homolog;
PBEF;
Visfatin
Research
Bioassay Publications (3)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (3)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| fk 866 | Mus musculus (house mouse) | IC50 | 0.0038 | 2 | 2 |
| gne-618 | Mus musculus (house mouse) | IC50 | 0.0590 | 1 | 1 |
| gne-617 | Mus musculus (house mouse) | IC50 | 0.0240 | 1 | 1 |
Drugs with Activation Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| gne-618 | Mus musculus (house mouse) | EC50 | 0.0700 | 1 | 1 |
| gne-617 | Mus musculus (house mouse) | EC50 | 0.0013 | 1 | 1 |
Identification of potent triazolylpyridine nicotinamide phosphoribosyltransferase (NAMPT) inhibitors bearing a 1,2,3-triazole tail group.European journal of medicinal chemistry, , Nov-01, Volume: 181, 2019
Identification of Novel Triazole-Based Nicotinamide Phosphoribosyltransferase (NAMPT) Inhibitors Endowed with Antiproliferative and Antiinflammatory Activity.Journal of medicinal chemistry, , 03-09, Volume: 60, Issue:5, 2017