glyburide has been researched along with Neuroblastoma in 4 studies
Glyburide: An antidiabetic sulfonylurea derivative with actions like those of chlorpropamide
glyburide : An N-sulfonylurea that is acetohexamide in which the acetyl group is replaced by a 2-(5-chloro-2-methoxybenzamido)ethyl group.
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Insulin and IGF-I binding to neuroblastoma cells (SK-N-MC) was increased by 13% and 7% respectively following a 24hr, incubation with the sulphonylurea glyburide." | 7.67 | Insulin and IGF-I receptors in neuroblastoma cells: increases in mRNA and binding produced by glyburide. ( LeRoith, D; Ota, A; Shen-Orr, Z, 1989) |
| "Insulin and IGF-I binding to neuroblastoma cells (SK-N-MC) was increased by 13% and 7% respectively following a 24hr, incubation with the sulphonylurea glyburide." | 3.67 | Insulin and IGF-I receptors in neuroblastoma cells: increases in mRNA and binding produced by glyburide. ( LeRoith, D; Ota, A; Shen-Orr, Z, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mochizuki-Oda, N | 1 |
| Takeuchi, Y | 1 |
| Matsumura, K | 1 |
| Oosawa, Y | 1 |
| Watanabe, Y | 1 |
| Rosati, B | 1 |
| Rocchetti, M | 1 |
| Zaza, A | 1 |
| Wanke, E | 1 |
| Reeve, HL | 1 |
| Vaughan, PF | 1 |
| Peers, C | 1 |
| Ota, A | 1 |
| Shen-Orr, Z | 1 |
| LeRoith, D | 1 |
4 other studies available for glyburide and Neuroblastoma
| Article | Year |
|---|---|
Hypoxia-induced catecholamine release and intracellular Ca2+ increase via suppression of K+ channels in cultured rat adrenal chromaffin cells.
Topics: Animals; Benzopyrans; Buffers; Calcium; Carotid Body; Catecholamines; Cell Hypoxia; CHO Cells; Chrom | 1997 |
Sulfonylureas blockade of neural and cardiac HERG channels.
Topics: Action Potentials; Animals; Cation Transport Proteins; Chromans; DNA-Binding Proteins; Dose-Response | 1998 |
Glibenclamide inhibits a voltage-gated K+ current in the human neuroblastoma cell line SH-SY5Y.
Topics: 4-Aminopyridine; Adenosine Triphosphate; Cadmium; Cell Line; Glyburide; Humans; Kinetics; Membrane P | 1992 |
Insulin and IGF-I receptors in neuroblastoma cells: increases in mRNA and binding produced by glyburide.
Topics: Deoxyglucose; Glyburide; Humans; Insulin-Like Growth Factor I; Neuroblastoma; Receptor, Insulin; Rec | 1989 |